This is a Validated Antibody Database (VAD) review about mouse Pdx1, based on 27 published articles (read how Labome selects the articles), using Pdx1 antibody in all methods. It is aimed to help Labome visitors find the most suited Pdx1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Pdx1 synonym: IDX-1; IPF-1; Ipf1; Mody4; STF-1; pdx-1

Abcam
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5e
Abcam Pdx1 antibody (Abcam, ab47267) was used in immunohistochemistry - paraffin section on mouse samples (fig 5e). Oncogene (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 6c
Abcam Pdx1 antibody (Abcam, ab47267) was used in immunohistochemistry - paraffin section on mouse samples at 1:400 (fig 6c). Int J Mol Sci (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig s4b
Abcam Pdx1 antibody (Abcam, 47267) was used in immunohistochemistry on mouse samples (fig s4b). Cell Rep (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:5000; loading ...; fig 6b
Abcam Pdx1 antibody (Abcam, ab47267) was used in immunohistochemistry - frozen section on mouse samples at 1:5000 (fig 6b). Cell Death Discov (2021) ncbi
domestic rabbit monoclonal (EPR22002)
  • immunocytochemistry; mouse; loading ...; fig 5b
  • western blot; mouse; loading ...; fig 5c
Abcam Pdx1 antibody (Abcam, ab219207) was used in immunocytochemistry on mouse samples (fig 5b) and in western blot on mouse samples (fig 5c). Cell Rep (2021) ncbi
guinea-pigs polyclonal
  • immunohistochemistry; mouse; loading ...; fig 2o
Abcam Pdx1 antibody (Abcam, ab47308) was used in immunohistochemistry on mouse samples (fig 2o). Cell Rep (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 8a
Abcam Pdx1 antibody (Abcam, ab47267) was used in immunohistochemistry - paraffin section on mouse samples at 1:300 (fig 8a). Cells (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 5c
Abcam Pdx1 antibody (Abcam, ab47267) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 5c). Nat Commun (2020) ncbi
domestic goat polyclonal
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 1a
Abcam Pdx1 antibody (Abcam, ab47383) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 1a). Stem Cells Transl Med (2019) ncbi
domestic goat polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:5000; loading ...; fig e5h
Abcam Pdx1 antibody (Abcam, ab47383) was used in immunohistochemistry - paraffin section on mouse samples at 1:5000 (fig e5h). Nature (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 7f
Abcam Pdx1 antibody (Abcam, ab47267) was used in western blot on human samples (fig 7f). Nucleic Acids Res (2019) ncbi
domestic goat polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:5000; loading ...; fig s1a
Abcam Pdx1 antibody (Abcam, ab47383) was used in immunohistochemistry - paraffin section on mouse samples at 1:5000 (fig s1a). Nature (2017) ncbi
domestic goat polyclonal
  • immunohistochemistry; mouse; loading ...; fig 2
In order to compare the effects of losartan and telmisartan on pancreatic islets remodeling and glucose homeostasis in diet-induced obese mice, Abcam Pdx1 antibody (Abcam, ab47383) was used in immunohistochemistry on mouse samples (fig 2). Mol Cell Endocrinol (2017) ncbi
guinea-pigs polyclonal
  • flow cytometry; human; 1:10,000; loading ...; tbl 1
  • immunocytochemistry; human; 1:10,000; loading ...; tbl 1
In order to describe a method to produce human embryonic stem cell-derived Beta-like cells, Abcam Pdx1 antibody (Abcam, ab47308) was used in flow cytometry on human samples at 1:10,000 (tbl 1) and in immunocytochemistry on human samples at 1:10,000 (tbl 1). PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; hamsters; fig 4
  • western blot; hamsters; fig 5
  • western blot; rat; fig 1
Abcam Pdx1 antibody (Abcam, ab47267) was used in chromatin immunoprecipitation on hamsters samples (fig 4), in western blot on hamsters samples (fig 5) and in western blot on rat samples (fig 1). Mol Cell Endocrinol (2016) ncbi
domestic rabbit polyclonal
In order to examine the role of the LIM homeodomain transcription factor Isl1 in pyloric development, Abcam Pdx1 antibody (Abcam, ab47267) was used . BMC Biol (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-11)
  • western blot; mouse; 1:200; loading ...; fig 2g
Santa Cruz Biotechnology Pdx1 antibody (Santa Cruz, sc-390792) was used in western blot on mouse samples at 1:200 (fig 2g). FASEB J (2017) ncbi
mouse monoclonal (E-5)
  • immunocytochemistry; human; fig 6g
  • western blot; human; fig 6d
Santa Cruz Biotechnology Pdx1 antibody (SantaCruz, sc-390808) was used in immunocytochemistry on human samples (fig 6g) and in western blot on human samples (fig 6d). Sci Rep (2014) ncbi
BD Biosciences
mouse monoclonal (658A5)
  • flow cytometry; human; fig 3b
BD Biosciences Pdx1 antibody (BD Biosciences, 562161) was used in flow cytometry on human samples (fig 3b). Dev Cell (2022) ncbi
mouse monoclonal (658A5)
  • flow cytometry; human; 1:10; loading ...; fig 4s1c
BD Biosciences Pdx1 antibody (BD Biosciences, 562161) was used in flow cytometry on human samples at 1:10 (fig 4s1c). elife (2021) ncbi
mouse monoclonal (658A5)
  • flow cytometry; human; 1:80; fig 2b, s3a
BD Biosciences Pdx1 antibody (BD Biosciences, 562161) was used in flow cytometry on human samples at 1:80 (fig 2b, s3a). Diabetes (2021) ncbi
mouse monoclonal (658A5)
  • flow cytometry; human; 1:40; fig s1
In order to assess the impact of thyroid dysregulation on the development of human embryonic stem cells-derived progenitor cells in vivo, BD Biosciences Pdx1 antibody (BD, 562161) was used in flow cytometry on human samples at 1:40 (fig s1). Diabetes (2016) ncbi
Developmental Studies Hybridoma Bank
mouse monoclonal (F6A11)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2d
Developmental Studies Hybridoma Bank Pdx1 antibody (DSHB, F6A11) was used in immunohistochemistry - paraffin section on mouse samples (fig 2d). Dev Cell (2022) ncbi
mouse monoclonal (F109-D12)
  • immunohistochemistry; mouse; 1:20; loading ...; fig 1a
Developmental Studies Hybridoma Bank Pdx1 antibody (DSHB, F109-D12) was used in immunohistochemistry on mouse samples at 1:20 (fig 1a). elife (2021) ncbi
mouse monoclonal (F109-D12)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 2c
Developmental Studies Hybridoma Bank Pdx1 antibody (Developmental Studies Hybridoma Bank, F109-D12) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 2c). Sci Adv (2019) ncbi
mouse monoclonal (F109-D12)
  • immunohistochemistry; mouse; 1:200; loading ...; fig 3a, s9e
Developmental Studies Hybridoma Bank Pdx1 antibody (DSHB, F109-D12) was used in immunohistochemistry on mouse samples at 1:200 (fig 3a, s9e). Nat Commun (2019) ncbi
mouse monoclonal (F6A11)
  • immunocytochemistry; rat; loading ...; fig 2a
Developmental Studies Hybridoma Bank Pdx1 antibody (DHSB, F6A11) was used in immunocytochemistry on rat samples (fig 2a). PLoS ONE (2019) ncbi
mouse monoclonal (F109-D12)
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 2a
Developmental Studies Hybridoma Bank Pdx1 antibody (DSHB, F109-D12) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 2a). Dev Cell (2017) ncbi
Articles Reviewed
  1. Miguel Escalada I, Maestro M, Balboa D, Elek A, Bernal A, Bernardo E, et al. Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster. Dev Cell. 2022;57:1922-1936.e9 pubmed publisher
  2. Kidger A, Saville M, Rushworth L, Davidson J, Stellzig J, Ono M, et al. Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6. Oncogene. 2022;41:2811-2823 pubmed publisher
  3. Nahle A, Joseph Y, Pereira S, Mori Y, Poon F, Ghadieh H, et al. Nicotinamide Mononucleotide Prevents Free Fatty Acid-Induced Reduction in Glucose Tolerance by Decreasing Insulin Clearance. Int J Mol Sci. 2021;22: pubmed publisher
  4. Lupse B, Annamalai K, Ibrahim H, Kaur S, Geravandi S, Sarma B, et al. Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes. Cell Rep. 2021;36:109490 pubmed publisher
  5. Lasierra Losada M, Pauler M, Vandamme N, Goossens S, Berx G, Leppkes M, et al. Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells. Cell Death Discov. 2021;7:138 pubmed publisher
  6. Zewdu R, Mehrabad E, Ingram K, Fang P, Gillis K, Camolotto S, et al. An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. elife. 2021;10: pubmed publisher
  7. Zhang X, Wang X, Yuan Z, Radford S, Liu C, Libutti S, et al. Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis. Cell Rep. 2021;34:108830 pubmed publisher
  8. Geusz R, Wang A, Chiou J, Lancman J, Wetton N, Kefalopoulou S, et al. Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development. elife. 2021;10: pubmed publisher
  9. Montaser H, Patel K, Balboa D, Ibrahim H, Lithovius V, Näätänen A, et al. Loss of MANF Causes Childhood-Onset Syndromic Diabetes Due to Increased Endoplasmic Reticulum Stress. Diabetes. 2021;70:1006-1018 pubmed publisher
  10. Viloria K, Nasteska D, Briant L, Heising S, Larner D, Fine N, et al. Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion. Cell Rep. 2020;31:107761 pubmed publisher
  11. Pittala S, Levy I, De S, Kumar Pandey S, Melnikov N, Hyman T, et al. The VDAC1-based R-Tf-D-LP4 Peptide as a Potential Treatment for Diabetes Mellitus. Cells. 2020;9: pubmed publisher
  12. Zhu K, Lai Y, Cao H, Bai X, Liu C, Yan Q, et al. Kindlin-2 modulates MafA and β-catenin expression to regulate β-cell function and mass in mice. Nat Commun. 2020;11:484 pubmed publisher
  13. Francis R, Guo H, Streutker C, Ahmed M, Yung T, Dirks P, et al. Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer. Sci Adv. 2019;5:eaax8898 pubmed publisher
  14. Villani V, Thornton M, Zook H, Crook C, Grubbs B, Orlando G, et al. SOX9+/PTF1A+ Cells Define the Tip Progenitor Cells of the Human Fetal Pancreas of the Second Trimester. Stem Cells Transl Med. 2019;8:1249-1264 pubmed publisher
  15. Yung T, Poon F, Liang M, Coquenlorge S, McGaugh E, Hui C, et al. Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals. Nat Commun. 2019;10:4647 pubmed publisher
  16. Alsaeedi F, Wilson R, Candlish C, Ibrahim I, Leitch A, Abdelghany T, et al. Expression of serine/threonine protein kinase SGK1F promotes an hepatoblast state in stem cells directed to differentiate into hepatocytes. PLoS ONE. 2019;14:e0218135 pubmed publisher
  17. Shi Y, Gao W, Lytle N, Huang P, Yuan X, Dann A, et al. Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring. Nature. 2019;569:131-135 pubmed publisher
  18. Haldeman J, Conway A, Arlotto M, Slentz D, Muoio D, Becker T, et al. Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing. Nucleic Acids Res. 2019;47:e23 pubmed publisher
  19. Wei J, Ding D, Wang T, Liu Q, Lin Y. MiR-338 controls BPA-triggered pancreatic islet insulin secretory dysfunction from compensation to decompensation by targeting Pdx-1. FASEB J. 2017;31:5184-5195 pubmed publisher
  20. Krentz N, Van Hoof D, Li Z, Watanabe A, Tang M, Nian C, et al. Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors. Dev Cell. 2017;41:129-142.e6 pubmed publisher
  21. McCracken K, Aihara E, Martin B, Crawford C, Broda T, Treguier J, et al. Wnt/β-catenin promotes gastric fundus specification in mice and humans. Nature. 2017;541:182-187 pubmed publisher
  22. Graus Nunes F, Marinho T, Barbosa da Silva S, Aguila M, Mandarim de Lacerda C, Souza Mello V. Differential effects of angiotensin receptor blockers on pancreatic islet remodelling and glucose homeostasis in diet-induced obese mice. Mol Cell Endocrinol. 2017;439:54-64 pubmed publisher
  23. Massumi M, Pourasgari F, Nalla A, Batchuluun B, Nagy K, Neely E, et al. An Abbreviated Protocol for In Vitro Generation of Functional Human Embryonic Stem Cell-Derived Beta-Like Cells. PLoS ONE. 2016;11:e0164457 pubmed publisher
  24. Wang W, Shi Q, Guo T, Yang Z, Jia Z, Chen P, et al. PDX1 and ISL1 differentially coordinate with epigenetic modifications to regulate insulin gene expression in varied glucose concentrations. Mol Cell Endocrinol. 2016;428:38-48 pubmed publisher
  25. Bruin J, Saber N, O Dwyer S, Fox J, Mojibian M, Arora P, et al. Hypothyroidism Impairs Human Stem Cell-Derived Pancreatic Progenitor Cell Maturation in Mice. Diabetes. 2016;65:1297-309 pubmed publisher
  26. Pettinato G, Wen X, Zhang N. Formation of well-defined embryoid bodies from dissociated human induced pluripotent stem cells using microfabricated cell-repellent microwell arrays. Sci Rep. 2014;4:7402 pubmed publisher
  27. Li Y, Pan J, Wei C, Chen J, Liu Y, Liu J, et al. LIM homeodomain transcription factor Isl1 directs normal pyloric development by targeting Gata3. BMC Biol. 2014;12:25 pubmed publisher