This is a Validated Antibody Database (VAD) review about mouse Park2, based on 63 published articles (read how Labome selects the articles), using Park2 antibody in all methods. It is aimed to help Labome visitors find the most suited Park2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Park2 synonym: PRKN; E3 ubiquitin-protein ligase parkin; parkin RBR E3 ubiquitin-protein ligase; parkin protein

Knockout validation
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; rat; 1:1000; fig 1a
Cell Signaling Technology Park2 antibody (Cell Signaling, 2132) was used in western blot knockout validation on rat samples at 1:1000 (fig 1a). Sci Rep (2018) ncbi
Cell Signaling Technology
mouse monoclonal (PRK8)
  • western blot knockout validation; rat; 1:1000; fig 1a
Cell Signaling Technology Park2 antibody (Cell Signaling, 4211S) was used in western blot knockout validation on rat samples at 1:1000 (fig 1a). Sci Rep (2018) ncbi
Cell Signaling Technology
rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; 1:400; loading ...; fig 4a
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 4b
Cell Signaling Technology Park2 antibody (Cell Signaling, 2132S) was used in immunohistochemistry knockout validation on mouse samples at 1:400 (fig 4a) and in western blot knockout validation on mouse samples at 1:1000 (fig 4b). Autophagy (2017) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; fig 4
In order to investigate PINK1-Mfn2-Parkin-mediated mitophagy in mouse hearts, Cell Signaling Technology Park2 antibody (Cell Signaling, 2132) was used in western blot knockout validation on mouse samples at 1:1000 (fig 4). Science (2015) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000
Cell Signaling Technology Park2 antibody (Cell Signaling, 2132) was used in western blot knockout validation on mouse samples at 1:1000. Circ Res (2015) ncbi
Cell Signaling Technology
mouse monoclonal (PRK8)
  • immunohistochemistry knockout validation; mouse; fig 3
  • western blot knockout validation; mouse; fig 3
Cell Signaling Technology Park2 antibody (Cell Signaling Tech, 4211) was used in immunohistochemistry knockout validation on mouse samples (fig 3) and in western blot knockout validation on mouse samples (fig 3). Autophagy (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal
  • western blot; human; 1:1000; loading ...; fig 7a
Santa Cruz Biotechnology Park2 antibody (Santa, Prk8) was used in western blot on human samples at 1:1000 (fig 7a). BMC Biol (2018) ncbi
mouse monoclonal (PRK8)
  • western blot; human; 1:1000; loading ...; fig 7a
Santa Cruz Biotechnology Park2 antibody (Santa, Prk8) was used in western blot on human samples at 1:1000 (fig 7a). BMC Biol (2018) ncbi
mouse monoclonal (PRK8)
  • western blot; human; loading ...; fig 2a, 4a
Santa Cruz Biotechnology Park2 antibody (Santa Cruz, sc-32282) was used in western blot on human samples (fig 2a, 4a). Mol Cell (2017) ncbi
mouse monoclonal (PRK8)
  • immunocytochemistry; human; 1:500; loading ...; fig 7d
In order to analyze the impact of alpha-synuclein on mitochondrial responses to oxidative stress in neural cells, Santa Cruz Biotechnology Park2 antibody (Santa Cruz Biotechnology, sc-32282) was used in immunocytochemistry on human samples at 1:500 (fig 7d). Sci Rep (2017) ncbi
mouse monoclonal (PRK8)
  • western blot; human; 1:1000; loading ...; fig 6a
In order to characterize muscle biopsy specimens derived from patients with spinal and bulbar muscular atrophy, Santa Cruz Biotechnology Park2 antibody (Santa Cruz, Sc-32282) was used in western blot on human samples at 1:1000 (fig 6a). Hum Mol Genet (2017) ncbi
mouse monoclonal (PRK8)
  • immunocytochemistry; human; loading ...; fig 3b
  • western blot; human; loading ...; fig 3a
Santa Cruz Biotechnology Park2 antibody (Santa Cruz, sc-32282) was used in immunocytochemistry on human samples (fig 3b) and in western blot on human samples (fig 3a). Oncotarget (2017) ncbi
mouse monoclonal (PRK8)
  • immunocytochemistry; mouse; 1:100; fig 6C
In order to show that follicle-stimulating hormone promotes granulosa cell survival by suppressing oxidative stress-induced mitophagy, Santa Cruz Biotechnology Park2 antibody (Santa Cruz, sc-32282) was used in immunocytochemistry on mouse samples at 1:100 (fig 6C). Sci Rep (2016) ncbi
mouse monoclonal (PRK8)
  • immunocytochemistry; rat; 1:500; loading ...; fig 2b
In order to study the role of Miro phosphorylation in Parkin-dependent mitochondrial arrest, Santa Cruz Biotechnology Park2 antibody (Santa Cruz Biotechnology, SC-32282) was used in immunocytochemistry on rat samples at 1:500 (fig 2b). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (PRK8)
  • western blot; human; 1:1000; loading ...; fig s7g
Santa Cruz Biotechnology Park2 antibody (SantaCruz, sc-32282) was used in western blot on human samples at 1:1000 (fig s7g). Nat Commun (2016) ncbi
mouse monoclonal (PRK8)
  • western blot; African green monkey; loading ...; fig 3b
  • western blot; mouse; loading ...; fig 1b
In order to show that syntaxin-17 is required for the delivery of stress-induced PINK1/parkin-dependent mitochondrial-derived vesicles to the late endosome/lysosome, Santa Cruz Biotechnology Park2 antibody (Santa Cruz, sc-32282) was used in western blot on African green monkey samples (fig 3b) and in western blot on mouse samples (fig 1b). J Cell Biol (2016) ncbi
mouse monoclonal (PRK8)
  • western blot; human; loading ...; fig 1c
In order to investigate the contribution of PINK1 and PARKIN to cell death, Santa Cruz Biotechnology Park2 antibody (Santa Cruz, PRK8) was used in western blot on human samples (fig 1c). J Biol Chem (2016) ncbi
mouse monoclonal (PRK8)
  • proximity ligation assay; human; 1:200; fig 2
  • immunohistochemistry - paraffin section; human; fig 5
  • immunoprecipitation; human; fig 2
  • western blot; human; fig 1
In order to study how Parkin is responsible for polyubiquitination of apurinic/apyrimidinic endonuclease 1, Santa Cruz Biotechnology Park2 antibody (Santa Cruz, sc-32282) was used in proximity ligation assay on human samples at 1:200 (fig 2), in immunohistochemistry - paraffin section on human samples (fig 5), in immunoprecipitation on human samples (fig 2) and in western blot on human samples (fig 1). Mol Carcinog (2017) ncbi
mouse monoclonal (PRK8)
  • western blot; rat; fig 5
Santa Cruz Biotechnology Park2 antibody (Santa Cruz, 32282) was used in western blot on rat samples (fig 5). J Biol Chem (2016) ncbi
mouse monoclonal (PRK8)
  • western blot; human; fig s1c
Santa Cruz Biotechnology Park2 antibody (Santa Cruz, sc-32282) was used in western blot on human samples (fig s1c). J Cell Biol (2016) ncbi
mouse monoclonal (PRK8)
  • western blot; human; fig 3
Santa Cruz Biotechnology Park2 antibody (Santa Cruz, sc-32282) was used in western blot on human samples (fig 3). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (PRK8)
  • western blot; human; fig 1d
Santa Cruz Biotechnology Park2 antibody (Santa Cruz Biotechnology, PRK8) was used in western blot on human samples (fig 1d). Nat Commun (2015) ncbi
mouse monoclonal (PRK8)
  • western blot; human; fig s4c
Santa Cruz Biotechnology Park2 antibody (Santa Cruz Biotechnology, PRK8) was used in western blot on human samples (fig s4c). J Cell Biol (2015) ncbi
mouse monoclonal (PRK8)
  • immunohistochemistry; human; fig 12
  • western blot; human; fig 8
In order to investigate the contribution of the Trib3 signaling pathway to neuron death, Santa Cruz Biotechnology Park2 antibody (Santa Cruz Biotechnology, sc-32282) was used in immunohistochemistry on human samples (fig 12) and in western blot on human samples (fig 8). J Neurosci (2015) ncbi
mouse monoclonal (PRK8)
  • immunocytochemistry; human; 1:1000; fig 4
  • western blot; human; 1:5000; fig 2
Santa Cruz Biotechnology Park2 antibody (Santa Cruz, sc-32282) was used in immunocytochemistry on human samples at 1:1000 (fig 4) and in western blot on human samples at 1:5000 (fig 2). EMBO Rep (2015) ncbi
mouse monoclonal (PRK8)
  • western blot; rat; 1:1000; fig 1
In order to study alpha-synuclein tetramers, Santa Cruz Biotechnology Park2 antibody (Santa Cruz, PRK8) was used in western blot on rat samples at 1:1000 (fig 1). Nat Commun (2015) ncbi
mouse monoclonal (PRK8)
  • western blot; Rhesus monkey
Santa Cruz Biotechnology Park2 antibody (Santa Cruz Biotechnology, sc-32282) was used in western blot on Rhesus monkey samples . J Neurosci (2015) ncbi
mouse monoclonal (PRK8)
  • western blot; mouse
In order to study the effect of parkin deletion and acute knockdown on acetaminophen-induced mitophagy and liver injury in mice, Santa Cruz Biotechnology Park2 antibody (Santa Cruz Biotechnology, SC-32282) was used in western blot on mouse samples . J Biol Chem (2015) ncbi
mouse monoclonal (PRK8)
  • western blot; mouse; 1:250; loading ...; fig 4d
Santa Cruz Biotechnology Park2 antibody (Santa Cruz Biotechnology, sc32282) was used in western blot on mouse samples at 1:250 (fig 4d). Sci Rep (2015) ncbi
mouse monoclonal (PRK8)
  • western blot; human; fig 7
Santa Cruz Biotechnology Park2 antibody (santa Cruz, sc-32282) was used in western blot on human samples (fig 7). Autophagy (2015) ncbi
mouse monoclonal (PRK8)
  • immunocytochemistry; rat; 1:20
  • western blot; rat; 1:200
Santa Cruz Biotechnology Park2 antibody (Santa Cruz, sc-32282) was used in immunocytochemistry on rat samples at 1:20 and in western blot on rat samples at 1:200. Neurobiol Dis (2015) ncbi
mouse monoclonal (PRK8)
  • western blot; human
In order to explore the parkin-dependent regulation of apoptosis and the turnover of damaged mitochondria in various cell types, Santa Cruz Biotechnology Park2 antibody (Santa Cruz Biotechnology, sc-32282) was used in western blot on human samples . Cell Death Dis (2014) ncbi
mouse monoclonal (PRK8)
  • western blot; human; fig 4
Santa Cruz Biotechnology Park2 antibody (Santa Cruz Biotechnology, sc32282) was used in western blot on human samples (fig 4). FASEB J (2014) ncbi
mouse monoclonal (PRK8)
  • western blot; rat
  • western blot; human; fig 2
In order to study the existance of alpha- and beta-synuclein predomonantly as oligomers in normal neuronal and non-neuronal cells, Santa Cruz Biotechnology Park2 antibody (Santa Cruz, PRK8) was used in western blot on rat samples and in western blot on human samples (fig 2). J Biol Chem (2013) ncbi
Abcam
mouse monoclonal (PRK8)
  • western blot; human; loading ...; fig 7b
Abcam Park2 antibody (Abcam, ab77924) was used in western blot on human samples (fig 7b). Cell Syst (2017) ncbi
mouse monoclonal (PRK8)
  • immunocytochemistry; human; 1:500; fig 5
Abcam Park2 antibody (Abcam, ab77924) was used in immunocytochemistry on human samples at 1:500 (fig 5). Sci Rep (2016) ncbi
mouse monoclonal (PRK8)
  • western blot; mouse; loading ...; fig 3a
Abcam Park2 antibody (Abcam, ab77924) was used in western blot on mouse samples (fig 3a). J Gerontol A Biol Sci Med Sci (2017) ncbi
mouse monoclonal (PRK8)
  • immunoprecipitation; human; fig 2b
  • western blot; human; 1:1000; fig 1c
In order to report and characterize the interaction between BECN1 and PARK2, Abcam Park2 antibody (Abcam, ab77924) was used in immunoprecipitation on human samples (fig 2b) and in western blot on human samples at 1:1000 (fig 1c). Autophagy (2014) ncbi
mouse monoclonal (PRK8)
  • immunoprecipitation; human
  • western blot; human
Abcam Park2 antibody (abcam, ab77924) was used in immunoprecipitation on human samples and in western blot on human samples . PLoS ONE (2014) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; 1:500; fig 5
Proteintech Group Park2 antibody (Proteintech, 14060-1-AP) was used in western blot on human samples at 1:500 (fig 5). Autophagy (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; rat; 1:1000; fig 1a
Cell Signaling Technology Park2 antibody (Cell Signaling, 2132) was used in western blot knockout validation on rat samples at 1:1000 (fig 1a). Sci Rep (2018) ncbi
mouse monoclonal (PRK8)
  • western blot knockout validation; rat; 1:1000; fig 1a
Cell Signaling Technology Park2 antibody (Cell Signaling, 4211S) was used in western blot knockout validation on rat samples at 1:1000 (fig 1a). Sci Rep (2018) ncbi
mouse monoclonal (PRK8)
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology Park2 antibody (Cell Signaling Technology, PRK8) was used in western blot on human samples at 1:1000 (fig 4). Hum Mol Genet (2017) ncbi
mouse monoclonal (PRK8)
  • western blot; mouse; 1:1000; loading ...; fig s6c
In order to elucidate the mechanism by which the I4895T mutation in the type 1 ryanodine receptor/Ca(2+) release channel results in disease, Cell Signaling Technology Park2 antibody (Cell Signaling, 4211) was used in western blot on mouse samples at 1:1000 (fig s6c). Nat Commun (2017) ncbi
mouse monoclonal (PRK8)
  • western blot; mouse; loading ...; fig 2a
In order to elucidate the contribution of the Sac phosphatase domain of Synaptojanin 1 to neurological symptoms, Cell Signaling Technology Park2 antibody (Cell Signaling, 4211) was used in western blot on mouse samples (fig 2a). Neuron (2017) ncbi
rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; 1:400; loading ...; fig 4a
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 4b
Cell Signaling Technology Park2 antibody (Cell Signaling, 2132S) was used in immunohistochemistry knockout validation on mouse samples at 1:400 (fig 4a) and in western blot knockout validation on mouse samples at 1:1000 (fig 4b). Autophagy (2017) ncbi
mouse monoclonal (PRK8)
  • western blot; mouse; loading ...; fig 7a
Cell Signaling Technology Park2 antibody (Cell Signaling, 4211) was used in western blot on mouse samples (fig 7a). Neurobiol Dis (2017) ncbi
mouse monoclonal (PRK8)
  • western blot; mouse; fig 3a
In order to find that continued 26S proteasome dysfunction in mouse brain cortical neurons causes paranuclear accumulation of fragmented dysfunctional mitochondria, associated with earlier recruitment of Parkin and lysine 48-linked ubiquitination of mitochond, Cell Signaling Technology Park2 antibody (Cell Signaling, 4211) was used in western blot on mouse samples (fig 3a). Cell Death Dis (2017) ncbi
mouse monoclonal (PRK8)
  • western blot; human; 1:1000; loading ...; fig 1b
In order to recognize the inner mitochondrial membrane protein, prohibitin 2, as a crucial mitophagy receptor involved in targeting mitochondria for autophagic degradation, Cell Signaling Technology Park2 antibody (Cell signaling, mAb4211) was used in western blot on human samples at 1:1000 (fig 1b). Cell (2017) ncbi
mouse monoclonal (PRK8)
  • immunocytochemistry; human; 1:1000; fig 2a
In order to study the role of PEX13 in autophagy, Cell Signaling Technology Park2 antibody (Cell signaling, 4211) was used in immunocytochemistry on human samples at 1:1000 (fig 2a). EMBO Rep (2017) ncbi
mouse monoclonal (PRK8)
  • western blot; human; 1:1000; loading ...; fig 2a
Cell Signaling Technology Park2 antibody (Cell Signaling Technology, 4211) was used in western blot on human samples at 1:1000 (fig 2a). Brain (2017) ncbi
mouse monoclonal (PRK8)
  • western blot; human; loading ...; fig 5b
In order to demonstrate that miR-181a inhibits mitophagy, Cell Signaling Technology Park2 antibody (Cell Signaling, 4211) was used in western blot on human samples (fig 5b). Oncotarget (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; human; fig 2
  • western blot; human; fig 2
Cell Signaling Technology Park2 antibody (Cell Signaling, 2132) was used in immunohistochemistry on human samples (fig 2) and in western blot on human samples (fig 2). J Immunol (2016) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; fig 4
In order to investigate PINK1-Mfn2-Parkin-mediated mitophagy in mouse hearts, Cell Signaling Technology Park2 antibody (Cell Signaling, 2132) was used in western blot knockout validation on mouse samples at 1:1000 (fig 4). Science (2015) ncbi
mouse monoclonal (PRK8)
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 1
Cell Signaling Technology Park2 antibody (Cell signaling, 4211) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 1). Cell Death Dis (2015) ncbi
mouse monoclonal (PRK8)
  • immunoprecipitation; human
  • immunocytochemistry; human; fig 9
In order to investigate the contribution of the Trib3 signaling pathway to neuron death, Cell Signaling Technology Park2 antibody (Cell Signaling Technology, 4211) was used in immunoprecipitation on human samples and in immunocytochemistry on human samples (fig 9). J Neurosci (2015) ncbi
mouse monoclonal (PRK8)
  • western blot; scFv; 1:1000; fig 3
Cell Signaling Technology Park2 antibody (Cell Signaling Tech, 4211S) was used in western blot on scFv samples at 1:1000 (fig 3). Sci Rep (2015) ncbi
mouse monoclonal (PRK8)
  • western blot; mouse; 1:1000
In order to assess the effect of PINK1-deficiency on mitochondrial quality control in myocytes, Cell Signaling Technology Park2 antibody (Cell Signaling, 4211) was used in western blot on mouse samples at 1:1000. PLoS ONE (2015) ncbi
mouse monoclonal (PRK8)
  • western blot; human; 1:1000; loading ...; fig 7
Cell Signaling Technology Park2 antibody (Cell Signaling, 4211) was used in western blot on human samples at 1:1000 (fig 7). Mol Neurodegener (2015) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000
Cell Signaling Technology Park2 antibody (Cell Signaling, 2132) was used in western blot knockout validation on mouse samples at 1:1000. Circ Res (2015) ncbi
rabbit polyclonal
  • immunoprecipitation; mouse; 1:800; loading ...; fig 3
  • western blot; mouse; 1:800; loading ...; fig 3b
  • immunoprecipitation; human; 1:800; loading ...; fig 3
  • western blot; human; 1:800; loading ...; fig 3a
Cell Signaling Technology Park2 antibody (Cell Signaling, 2132S) was used in immunoprecipitation on mouse samples at 1:800 (fig 3), in western blot on mouse samples at 1:800 (fig 3b), in immunoprecipitation on human samples at 1:800 (fig 3) and in western blot on human samples at 1:800 (fig 3a). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:500; fig 2
Cell Signaling Technology Park2 antibody (Cell Signaling, #2132) was used in western blot on human samples at 1:500 (fig 2). Biochim Biophys Acta (2014) ncbi
mouse monoclonal (PRK8)
  • immunohistochemistry knockout validation; mouse; fig 3
  • western blot knockout validation; mouse; fig 3
Cell Signaling Technology Park2 antibody (Cell Signaling Tech, 4211) was used in immunohistochemistry knockout validation on mouse samples (fig 3) and in western blot knockout validation on mouse samples (fig 3). Autophagy (2014) ncbi
mouse monoclonal (PRK8)
  • western blot; rat; 1:1000
Cell Signaling Technology Park2 antibody (Cell Signaling, Prk8) was used in western blot on rat samples at 1:1000. J Neurochem (2014) ncbi
Sigma-Aldrich
mouse monoclonal (PRK8)
  • immunocytochemistry; human; fig 6
  • western blot; human; 1:2000; fig 7
In order to investigate how PINK1 recruits Parkin, Sigma-Aldrich Park2 antibody (Sigma-Aldrich, PRK8) was used in immunocytochemistry on human samples (fig 6) and in western blot on human samples at 1:2000 (fig 7). J Cell Biol (2015) ncbi
mouse monoclonal (PRK8)
  • immunocytochemistry; mouse; loading ...; fig 3b
  • western blot; mouse; loading ...; fig 2c
Sigma-Aldrich Park2 antibody (Sigma, P6248) was used in immunocytochemistry on mouse samples (fig 3b) and in western blot on mouse samples (fig 2c). Hum Mol Genet (2015) ncbi
mouse monoclonal (PRK8)
  • western blot; mouse; 1:5000; fig 1
Sigma-Aldrich Park2 antibody (Sigma, PRK8) was used in western blot on mouse samples at 1:5000 (fig 1). Cell Res (2015) ncbi
mouse monoclonal (PRK8)
  • immunoprecipitation; mouse; 1:6000; fig 2
  • western blot; mouse; 1:6000; fig 2
  • immunoprecipitation; human; 1:6000; fig 2
  • western blot; human; 1:6000; fig 2
In order to elucidate how mutations in parkin result in autosomal recessive juvenile parkinsonism, Sigma-Aldrich Park2 antibody (Sigma, P6248) was used in immunoprecipitation on mouse samples at 1:6000 (fig 2), in western blot on mouse samples at 1:6000 (fig 2), in immunoprecipitation on human samples at 1:6000 (fig 2) and in western blot on human samples at 1:6000 (fig 2). Nat Commun (2014) ncbi
mouse monoclonal (PRK8)
  • western blot; human; 1:2000
In order to report PINK1 phosphorylates ubiquitin which results in parkin activation, Sigma-Aldrich Park2 antibody (Sigma, PRK8) was used in western blot on human samples at 1:2000. Nature (2014) ncbi
mouse monoclonal (PRK8)
  • western blot; mouse
  • immunocytochemistry; African green monkey
Sigma-Aldrich Park2 antibody (Sigma-Aldrich, PRK8) was used in western blot on mouse samples and in immunocytochemistry on African green monkey samples . J Biol Chem (2014) ncbi
EMD Millipore
mouse monoclonal (PRK8)
  • immunocytochemistry; human; loading ...; fig 4a
EMD Millipore Park2 antibody (Millipore, Park8) was used in immunocytochemistry on human samples (fig 4a). Cell Death Differ (2015) ncbi
mouse monoclonal (PRK8)
  • western blot; mouse
EMD Millipore Park2 antibody (Millipore, MAB5512) was used in western blot on mouse samples . Diabetologia (2013) ncbi
Articles Reviewed
  1. Zhu M, Cortese G, Waites C. Parkinson's disease-linked Parkin mutations impair glutamatergic signaling in hippocampal neurons. BMC Biol. 2018;16:100 pubmed publisher
  2. Gemechu J, Sharma A, Yu D, Xie Y, Merkel O, Moszczynska A. Characterization of Dopaminergic System in the Striatum of Young Adult Park2-/- Knockout Rats. Sci Rep. 2018;8:1517 pubmed publisher
  3. Malty R, Aoki H, Kumar A, Phanse S, Amin S, Zhang Q, et al. A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling. Cell Syst. 2017;5:564-577.e12 pubmed publisher
  4. Shiba Fukushima K, Ishikawa K, Inoshita T, Izawa N, Takanashi M, Sato S, et al. Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson's disease. Hum Mol Genet. 2017;26:3172-3185 pubmed publisher
  5. Lee C, Hanna A, Wang H, Dagnino Acosta A, Joshi A, Knoblauch M, et al. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017;8:14659 pubmed publisher
  6. Gupta A, Anjomani Virmouni S, Koundouros N, Dimitriadi M, Choo Wing R, Valle A, et al. PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation. Mol Cell. 2017;65:999-1013.e7 pubmed publisher
  7. Cao M, Wu Y, Ashrafi G, McCartney A, Wheeler H, Bushong E, et al. Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons. Neuron. 2017;93:882-896.e5 pubmed publisher
  8. Menges S, Minakaki G, Schaefer P, Meixner H, Prots I, Schlötzer Schrehardt U, et al. Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress. Sci Rep. 2017;7:42942 pubmed publisher
  9. Shen Z, Zheng Y, Wu J, Chen Y, Wu X, Zhou Y, et al. PARK2-dependent mitophagy induced by acidic postconditioning protects against focal cerebral ischemia and extends the reperfusion window. Autophagy. 2017;13:473-485 pubmed publisher
  10. Borgia D, Malena A, Spinazzi M, Desbats M, Salviati L, Russell A, et al. Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients. Hum Mol Genet. 2017;26:1087-1103 pubmed publisher
  11. Upadhyay M, Agarwal S, Bhadauriya P, Ganesh S. Loss of laforin or malin results in increased Drp1 level and concomitant mitochondrial fragmentation in Lafora disease mouse models. Neurobiol Dis. 2017;100:39-51 pubmed publisher
  12. Li G, Fu R, Shen H, Zhou J, Hu X, Liu Y, et al. Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Oncotarget. 2017;8:10359-10374 pubmed publisher
  13. Ugun Klusek A, Tatham M, Elkharaz J, Constantin Teodosiu D, Lawler K, Mohamed H, et al. Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway. Cell Death Dis. 2017;8:e2531 pubmed publisher
  14. Wei Y, Chiang W, Sumpter R, Mishra P, Levine B. Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor. Cell. 2017;168:224-238.e10 pubmed publisher
  15. Shen M, Jiang Y, Guan Z, Cao Y, Sun S, Liu H. FSH protects mouse granulosa cells from oxidative damage by repressing mitophagy. Sci Rep. 2016;6:38090 pubmed publisher
  16. Lee M, Sumpter R, Zou Z, Sirasanagandla S, Wei Y, Mishra P, et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 2017;18:48-60 pubmed publisher
  17. Puschmann A, Fiesel F, Caulfield T, Hudec R, Ando M, Truban D, et al. Heterozygous PINK1 p.G411S increases risk of Parkinson's disease via a dominant-negative mechanism. Brain. 2017;140:98-117 pubmed publisher
  18. Shlevkov E, Kramer T, Schapansky J, LaVoie M, Schwarz T. Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility. Proc Natl Acad Sci U S A. 2016;113:E6097-E6106 pubmed
  19. Guo X, Sun X, Hu D, Wang Y, Fujioka H, Vyas R, et al. VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease. Nat Commun. 2016;7:12646 pubmed publisher
  20. McLelland G, Lee S, McBride H, Fon E. Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system. J Cell Biol. 2016;214:275-91 pubmed publisher
  21. Akabane S, Matsuzaki K, Yamashita S, Arai K, Okatsu K, Kanki T, et al. Constitutive Activation of PINK1 Protein Leads to Proteasome-mediated and Non-apoptotic Cell Death Independently of Mitochondrial Autophagy. J Biol Chem. 2016;291:16162-74 pubmed publisher
  22. Cheng M, Liu L, Lao Y, Liao W, Liao M, Luo X, et al. MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis. Oncotarget. 2016;7:42274-42287 pubmed publisher
  23. Kobayashi K, Araya J, Minagawa S, Hara H, Saito N, Kadota T, et al. Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis. J Immunol. 2016;197:504-16 pubmed publisher
  24. Scott T, Wicker C, Suganya R, Dhar B, Pittman T, Horbinski C, et al. Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin. Mol Carcinog. 2017;56:325-336 pubmed publisher
  25. Qvit N, Joshi A, Cunningham A, Ferreira J, Mochly Rosen D. Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death. J Biol Chem. 2016;291:13608-21 pubmed publisher
  26. Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, et al. Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways. Autophagy. 2016;12:999-1014 pubmed publisher
  27. Pryde K, Smith H, Chau K, Schapira A. PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy. J Cell Biol. 2016;213:163-71 pubmed publisher
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