This is a Validated Antibody Database (VAD) review about mouse Pak3, based on 11 published articles (read how Labome selects the articles), using Pak3 antibody in all methods. It is aimed to help Labome visitors find the most suited Pak3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Pak3 synonym: PAK-3; Pak65alpha; Pak65beta; Stk4; serine/threonine-protein kinase PAK 3; CDC42/RAC effector kinase PAK-B; beta-PAK; p21 protein (Cdc42/Rac)-activated kinase 3; p21-activated kinase 3

Santa Cruz Biotechnology
mouse monoclonal (A-6)
  • western blot; mouse; loading ...; fig 5D
Santa Cruz Biotechnology Pak3 antibody (Santa Cruz, sc-166887) was used in western blot on mouse samples (fig 5D). elife (2017) ncbi
mouse monoclonal (D-8)
  • immunohistochemistry; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 3b
Santa Cruz Biotechnology Pak3 antibody (Santa Cruz Biotechnology, sc-166174) was used in immunohistochemistry on human samples (fig 2a) and in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
mouse monoclonal (A-6)
  • western blot; human; 1:400
Santa Cruz Biotechnology Pak3 antibody (Santa Cruz, sc-166887) was used in western blot on human samples at 1:400. PLoS ONE (2016) ncbi
mouse monoclonal (A-6)
  • immunoprecipitation; human; fig 6
  • western blot; human; fig 5
Santa Cruz Biotechnology Pak3 antibody (Santa Cruz Biotechnologies, sc-166887) was used in immunoprecipitation on human samples (fig 6) and in western blot on human samples (fig 5). Blood (2015) ncbi
Abnova
mouse monoclonal (3A12)
  • western blot; human; 1:400; fig 1
Abnova Pak3 antibody (Abnova, H00005063-M08) was used in western blot on human samples at 1:400 (fig 1). PLoS ONE (2016) ncbi
R&D Systems
sheep polyclonal
  • immunohistochemistry - paraffin section; hamsters; 1:80
  • immunocytochemistry; hamsters; 1:50
  • western blot; hamsters
R&D Systems Pak3 antibody (R&D Systems, AF6897) was used in immunohistochemistry - paraffin section on hamsters samples at 1:80, in immunocytochemistry on hamsters samples at 1:50 and in western blot on hamsters samples . Med Microbiol Immunol (2014) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; mouse; 1:1000; fig s8
Cell Signaling Technology Pak3 antibody (Cell Signalling, 2609) was used in western blot on mouse samples at 1:1000 (fig s8). Nat Commun (2016) ncbi
rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig 1
  • western blot; mouse; 1:1000; loading ...; fig 1
Cell Signaling Technology Pak3 antibody (Cell Signaling, 2609) was used in immunoprecipitation on mouse samples (fig 1) and in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; mouse
In order to study the molecular mechanisms underlying malignant changes of meningioma cells, Cell Signaling Technology Pak3 antibody (Cell Signaling Technology, 2609) was used in western blot on mouse samples . Oncotarget (2015) ncbi
Sigma-Aldrich
mouse monoclonal (3A12)
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 5a
Sigma-Aldrich Pak3 antibody (Sigma-Aldrich, WH0005063M8) was used in immunohistochemistry - frozen section on mouse samples at 1:50 (fig 5a). J Neurosci (2017) ncbi
EMD Millipore
rabbit polyclonal
  • western blot; rat; 1:500
In order to study the temporal and spatial relationship between dendritic protein synthesis and actin cytoskeleton reorganization, EMD Millipore Pak3 antibody (Millipore, 06-902) was used in western blot on rat samples at 1:500. J Neurosci (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
In order to study 5-HT7R in a mouse model of Rett syndrome, EMD Millipore Pak3 antibody (Upstate, 06902) was used in western blot on mouse samples at 1:1000. Neuropsychopharmacology (2014) ncbi
Articles Reviewed
  1. Jeannot P, Nowosad A, Perchey R, Callot C, Bennana E, Katsube T, et al. p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway. elife. 2017;6: pubmed publisher
  2. Hickox A, Wong A, Pak K, Strojny C, Ramirez M, Yates J, et al. Global Analysis of Protein Expression of Inner Ear Hair Cells. J Neurosci. 2017;37:1320-1339 pubmed publisher
  3. Martin K, Pritchett J, Llewellyn J, Mullan A, Athwal V, Dobie R, et al. PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis. Nat Commun. 2016;7:12502 pubmed publisher
  4. Yuan W, Guo Y, Li X, Deng M, Shen Z, Bo C, et al. MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway. Oncotarget. 2016;7:60230-60244 pubmed publisher
  5. Wang Y, Gratzke C, Tamalunas A, Wiemer N, Ciotkowska A, Rutz B, et al. P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate. PLoS ONE. 2016;11:e0153312 pubmed publisher
  6. Singh N, Kotla S, Dyukova E, Traylor J, Orr A, Chernoff J, et al. Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice. Nat Commun. 2015;6:7450 pubmed publisher
  7. Briz V, Zhu G, Wang Y, Liu Y, Avetisyan M, Bi X, et al. Activity-dependent rapid local RhoA synthesis is required for hippocampal synaptic plasticity. J Neurosci. 2015;35:2269-82 pubmed publisher
  8. Chow H, Dong B, Duron S, Campbell D, Ong C, Hoeflich K, et al. Group I Paks as therapeutic targets in NF2-deficient meningioma. Oncotarget. 2015;6:1981-94 pubmed
  9. Badolia R, Manne B, Dangelmaier C, Chernoff J, Kunapuli S. Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets. Blood. 2015;125:175-84 pubmed publisher
  10. Meng G, Tian C, Wang H, Xu Y, Zhang B, Shi Q, et al. Remarkable reductions of PAKs in the brain tissues of scrapie-infected rodent possibly linked closely with neuron loss. Med Microbiol Immunol. 2014;203:291-302 pubmed publisher
  11. De Filippis B, Nativio P, Fabbri A, Ricceri L, Adriani W, Lacivita E, et al. Pharmacological stimulation of the brain serotonin receptor 7 as a novel therapeutic approach for Rett syndrome. Neuropsychopharmacology. 2014;39:2506-18 pubmed publisher