This is a Validated Antibody Database (VAD) review about mouse Pak2, based on 13 published articles (read how Labome selects the articles), using Pak2 antibody in all methods. It is aimed to help Labome visitors find the most suited Pak2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Pak2 synonym: 5330420P17Rik; A130002K10Rik; AI836325; D16Ertd269e; PAK-2; mKIAA4182

Santa Cruz Biotechnology
mouse monoclonal (A-6)
  • western blot; mouse; loading ...; fig 5D
Santa Cruz Biotechnology Pak2 antibody (Santa Cruz, sc-166887) was used in western blot on mouse samples (fig 5D). elife (2017) ncbi
mouse monoclonal (D-8)
  • immunohistochemistry; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 3b
Santa Cruz Biotechnology Pak2 antibody (Santa Cruz Biotechnology, sc-166174) was used in immunohistochemistry on human samples (fig 2a) and in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
mouse monoclonal (E-9)
  • western blot; human; 1:400
Santa Cruz Biotechnology Pak2 antibody (Santa Cruz, sc-373740) was used in western blot on human samples at 1:400. PLoS ONE (2016) ncbi
mouse monoclonal (A-6)
  • western blot; human; 1:400
Santa Cruz Biotechnology Pak2 antibody (Santa Cruz, sc-166887) was used in western blot on human samples at 1:400. PLoS ONE (2016) ncbi
mouse monoclonal (A-6)
  • immunoprecipitation; human; fig 6
  • western blot; human; fig 5
Santa Cruz Biotechnology Pak2 antibody (Santa Cruz Biotechnologies, sc-166887) was used in immunoprecipitation on human samples (fig 6) and in western blot on human samples (fig 5). Blood (2015) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology Pak2 antibody (Cell Signaling, 2608S) was used in western blot on human samples at 1:1000 (fig 2b). Nat Commun (2022) ncbi
domestic rabbit monoclonal (C17A10)
  • western blot; mouse; 1:500; loading ...; fig 5c
Cell Signaling Technology Pak2 antibody (Cell signaling, 2615) was used in western blot on mouse samples at 1:500 (fig 5c). Front Physiol (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:200; loading ...; fig 6i
  • western blot; mouse; 1:1000; loading ...; fig 6f
Cell Signaling Technology Pak2 antibody (Cell Signaling, 2608) was used in immunocytochemistry on mouse samples at 1:200 (fig 6i) and in western blot on mouse samples at 1:1000 (fig 6f). elife (2019) ncbi
domestic rabbit monoclonal (C17A10)
  • western blot; human; 1:2000; loading ...; fig 2c
Cell Signaling Technology Pak2 antibody (Cell Signaling, 2615) was used in western blot on human samples at 1:2000 (fig 2c). Genes Dev (2017) ncbi
domestic rabbit monoclonal (C17A10)
  • western blot; human; loading ...; fig 9e
Cell Signaling Technology Pak2 antibody (Cell Signaling, 2615) was used in western blot on human samples (fig 9e). J Clin Invest (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology Pak2 antibody (Cell Signaling, 2608) was used in western blot on human samples at 1:1000 (fig st1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (C17A10)
  • western blot; human; 1:2000; fig 4
Cell Signaling Technology Pak2 antibody (Cell Signalling, 2615) was used in western blot on human samples at 1:2000 (fig 4). Nat Commun (2015) ncbi
domestic rabbit monoclonal (C17A10)
  • western blot; human; 1:1000; fig  7
Cell Signaling Technology Pak2 antibody (Cell Signalling Technology, 2615) was used in western blot on human samples at 1:1000 (fig  7). Cell Signal (2015) ncbi
domestic rabbit monoclonal (C17A10)
  • western blot; human
Cell Signaling Technology Pak2 antibody (Cell Signaling, 2615) was used in western blot on human samples . PLoS ONE (2014) ncbi
Articles Reviewed
  1. Esposito D, Pant I, Shen Y, Qiao R, Yang X, Bai Y, et al. ROCK1 mechano-signaling dependency of human malignancies driven by TEAD/YAP activation. Nat Commun. 2022;13:703 pubmed publisher
  2. Barbé C, Loumaye A, Lause P, Ritvos O, Thissen J. p21-Activated Kinase 1 Is Permissive for the Skeletal Muscle Hypertrophy Induced by Myostatin Inhibition. Front Physiol. 2021;12:677746 pubmed publisher
  3. Laurin M, Gomez N, Levorse J, Sendoel A, Sribour M, Fuchs E. An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis. elife. 2019;8: pubmed publisher
  4. Yue X, Zhang C, Zhao Y, Liu J, Lin A, Tan V, et al. Gain-of-function mutant p53 activates small GTPase Rac1 through SUMOylation to promote tumor progression. Genes Dev. 2017;31:1641-1654 pubmed publisher
  5. Kim J, Kim Y, Kim J, Park D, Bae H, Lee D, et al. YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation. J Clin Invest. 2017;127:3441-3461 pubmed publisher
  6. Jeannot P, Nowosad A, Perchey R, Callot C, Bennana E, Katsube T, et al. p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway. elife. 2017;6: pubmed publisher
  7. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  8. Yuan W, Guo Y, Li X, Deng M, Shen Z, Bo C, et al. MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway. Oncotarget. 2016;7:60230-60244 pubmed publisher
  9. Wang Y, Gratzke C, Tamalunas A, Wiemer N, Ciotkowska A, Rutz B, et al. P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate. PLoS ONE. 2016;11:e0153312 pubmed publisher
  10. Whalley H, Porter A, Diamantopoulou Z, White G, Castañeda Saucedo E, Malliri A. Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation. Nat Commun. 2015;6:7437 pubmed publisher
  11. Tanaka T, Iino M. Sec8 regulates cytokeratin8 phosphorylation and cell migration by controlling the ERK and p38 MAPK signalling pathways. Cell Signal. 2015;27:1110-9 pubmed publisher
  12. Badolia R, Manne B, Dangelmaier C, Chernoff J, Kunapuli S. Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets. Blood. 2015;125:175-84 pubmed publisher
  13. Kuzelova K, Grebenová D, Holoubek A, Roselova P, Obr A. Group I PAK inhibitor IPA-3 induces cell death and affects cell adhesivity to fibronectin in human hematopoietic cells. PLoS ONE. 2014;9:e92560 pubmed publisher