This is a Validated Antibody Database (VAD) review about mouse Pak1, based on 16 published articles (read how Labome selects the articles), using Pak1 antibody in all methods. It is aimed to help Labome visitors find the most suited Pak1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Pak1 synonym: AW045634; PAK-1; Paka

Knockout validation
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 2a
Cell Signaling Technology Pak1 antibody (Cell signaling, 2602) was used in western blot knockout validation on mouse samples at 1:1000 (fig 2a). Front Physiol (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-6)
  • western blot; mouse; loading ...; fig 5D
Santa Cruz Biotechnology Pak1 antibody (Santa Cruz, sc-166887) was used in western blot on mouse samples (fig 5D). elife (2017) ncbi
mouse monoclonal (D-8)
  • immunohistochemistry; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 3b
Santa Cruz Biotechnology Pak1 antibody (Santa Cruz Biotechnology, sc-166174) was used in immunohistochemistry on human samples (fig 2a) and in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
mouse monoclonal (A-6)
  • western blot; human; 1:400
Santa Cruz Biotechnology Pak1 antibody (Santa Cruz, sc-166887) was used in western blot on human samples at 1:400. PLoS ONE (2016) ncbi
mouse monoclonal (A-6)
  • immunoprecipitation; human; fig 6
  • western blot; human; fig 5
Santa Cruz Biotechnology Pak1 antibody (Santa Cruz Biotechnologies, sc-166887) was used in immunoprecipitation on human samples (fig 6) and in western blot on human samples (fig 5). Blood (2015) ncbi
Abcam
domestic rabbit monoclonal (EP656Y)
  • western blot; rat; 1:1000; loading ...; fig 4a
  • western blot; mouse; 1:1000; loading ...; fig 4c
Abcam Pak1 antibody (Abcam, ab40795) was used in western blot on rat samples at 1:1000 (fig 4a) and in western blot on mouse samples at 1:1000 (fig 4c). J Biol Chem (2017) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 2a
Cell Signaling Technology Pak1 antibody (Cell signaling, 2602) was used in western blot knockout validation on mouse samples at 1:1000 (fig 2a). Front Physiol (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 4e
Cell Signaling Technology Pak1 antibody (Cell Signaling, 2602) was used in western blot on human samples at 1:1000 (fig 4e). Front Cell Dev Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 6e
Cell Signaling Technology Pak1 antibody (Cell Signaling, 2602) was used in western blot on mouse samples at 1:1000 (fig 6e). elife (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 6e
Cell Signaling Technology Pak1 antibody (Cell Signaling, 2604) was used in western blot on mouse samples at 1:1000 (fig 6e). elife (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; fig 3g
Cell Signaling Technology Pak1 antibody (Cell Signaling, 2604) was used in western blot on human samples at 1:500 (fig 3g). Nat Commun (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4d
Cell Signaling Technology Pak1 antibody (Cell Signaling, 2604) was used in western blot on mouse samples at 1:1000 (fig 4d). Aging Cell (2018) ncbi
domestic rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology Pak1 antibody (Cell Signaling, 2602) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 2c
Cell Signaling Technology Pak1 antibody (Cell Signaling, 2602) was used in western blot on human samples at 1:2000 (fig 2c). Genes Dev (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:200; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology Pak1 antibody (Cell Signaling, 2604) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000
Cell Signaling Technology Pak1 antibody (Cell Signalling, 2604) was used in western blot on mouse samples at 1:1000. Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 5
Cell Signaling Technology Pak1 antibody (Cell Signalling, 2602) was used in western blot on mouse samples at 1:1000 (fig 5). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 3a
In order to investigate the interaction between MUC13 and HER2, Cell Signaling Technology Pak1 antibody (Cell Signaling, 2602) was used in western blot on human samples (fig 3a). Oncogene (2017) ncbi
MilliporeSigma
mouse monoclonal (PK-18)
  • immunohistochemistry; mouse; 1:500; fig 6
MilliporeSigma Pak1 antibody (Sigma, P3237) was used in immunohistochemistry on mouse samples at 1:500 (fig 6). J Cell Sci (2016) ncbi
Articles Reviewed
  1. Barbé C, Loumaye A, Lause P, Ritvos O, Thissen J. p21-Activated Kinase 1 Is Permissive for the Skeletal Muscle Hypertrophy Induced by Myostatin Inhibition. Front Physiol. 2021;12:677746 pubmed publisher
  2. Shi X, Wen Z, Wang Y, Liu Y, Shi K, Jiu Y. Feedback-Driven Mechanisms Between Phosphorylated Caveolin-1 and Contractile Actin Assemblies Instruct Persistent Cell Migration. Front Cell Dev Biol. 2021;9:665919 pubmed publisher
  3. Laurin M, Gomez N, Levorse J, Sendoel A, Sribour M, Fuchs E. An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis. elife. 2019;8: pubmed publisher
  4. Genet G, Boyé K, Mathivet T, Ola R, Zhang F, Dubrac A, et al. Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis. Nat Commun. 2019;10:2350 pubmed publisher
  5. Baglietto Vargas D, Prieto G, Limon A, Forner S, Rodriguez Ortiz C, Ikemura K, et al. Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease. Aging Cell. 2018;17:e12791 pubmed publisher
  6. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  7. Yue X, Zhang C, Zhao Y, Liu J, Lin A, Tan V, et al. Gain-of-function mutant p53 activates small GTPase Rac1 through SUMOylation to promote tumor progression. Genes Dev. 2017;31:1641-1654 pubmed publisher
  8. Chang J, Ni Y, Han L, Sinnett Smith J, Jacamo R, Rey O, et al. Protein kinase D1 (PKD1) phosphorylation on Ser203 by type I p21-activated kinase (PAK) regulates PKD1 localization. J Biol Chem. 2017;292:9523-9539 pubmed publisher
  9. Jeannot P, Nowosad A, Perchey R, Callot C, Bennana E, Katsube T, et al. p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway. elife. 2017;6: pubmed publisher
  10. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  11. Martin K, Pritchett J, Llewellyn J, Mullan A, Athwal V, Dobie R, et al. PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis. Nat Commun. 2016;7:12502 pubmed publisher
  12. Yuan W, Guo Y, Li X, Deng M, Shen Z, Bo C, et al. MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway. Oncotarget. 2016;7:60230-60244 pubmed publisher
  13. Khan S, Sikander M, Ebeling M, Ganju A, Kumari S, Yallapu M, et al. MUC13 interaction with receptor tyrosine kinase HER2 drives pancreatic ductal adenocarcinoma progression. Oncogene. 2017;36:491-500 pubmed publisher
  14. Wang Y, Gratzke C, Tamalunas A, Wiemer N, Ciotkowska A, Rutz B, et al. P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate. PLoS ONE. 2016;11:e0153312 pubmed publisher
  15. Jimeno D, Gómez C, Calzada N, de la Villa P, Lillo C, Santos E. RASGRF2 controls nuclear migration in postnatal retinal cone photoreceptors. J Cell Sci. 2016;129:729-42 pubmed publisher
  16. Badolia R, Manne B, Dangelmaier C, Chernoff J, Kunapuli S. Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets. Blood. 2015;125:175-84 pubmed publisher