This is a Validated Antibody Database (VAD) review about mouse Numb, based on 11 published articles (read how Labome selects the articles), using Numb antibody in all methods. It is aimed to help Labome visitors find the most suited Numb antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Numb synonym: Nb

Santa Cruz Biotechnology
mouse monoclonal (48)
  • western blot; human; 1:1000; loading ...; fig 4a
Santa Cruz Biotechnology Numb antibody (Santa Cruz, sc-136554) was used in western blot on human samples at 1:1000 (fig 4a). Apoptosis (2017) ncbi
mouse monoclonal (48)
  • immunocytochemistry; dogs; 1:200; loading ...; fig 6b
In order to find and characterize the interaction between Eps15 and pS227-FIP2, Santa Cruz Biotechnology Numb antibody (Santa Cruz Biotechnology, SC-136554) was used in immunocytochemistry on dogs samples at 1:200 (fig 6b). Mol Biol Cell (2017) ncbi
Abcam
domestic goat polyclonal
  • western blot; mouse; loading ...; fig s3a
In order to study NaV1.7 trafficking, Abcam Numb antibody (Abcam, ab4147) was used in western blot on mouse samples (fig s3a). Proc Natl Acad Sci U S A (2016) ncbi
domestic goat polyclonal
  • immunohistochemistry - frozen section; mouse; 1:400; fig 1s2
In order to determine the contribution of TBC1D3 to cortical folding, Abcam Numb antibody (Abcam, ab4147) was used in immunohistochemistry - frozen section on mouse samples at 1:400 (fig 1s2). elife (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C29G11)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2e
  • immunoprecipitation; mouse; loading ...; fig 4d
  • western blot; mouse; loading ...; fig 1a
Cell Signaling Technology Numb antibody (Cell Signaling, 2756) was used in immunohistochemistry - frozen section on mouse samples (fig 2e), in immunoprecipitation on mouse samples (fig 4d) and in western blot on mouse samples (fig 1a). Front Cell Dev Biol (2021) ncbi
domestic rabbit monoclonal (C29G11)
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 8a
Cell Signaling Technology Numb antibody (Cell Signaling, 2756) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 8a). Mol Biol Cell (2021) ncbi
domestic rabbit monoclonal (C29G11)
  • western blot; human; loading ...; fig 3e
Cell Signaling Technology Numb antibody (Cell Signaling Technology, 2756) was used in western blot on human samples (fig 3e). Cancer Res (2017) ncbi
domestic rabbit monoclonal (C29G11)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s1b
  • western blot; mouse; 1:250; loading ...; fig 3c
Cell Signaling Technology Numb antibody (Cell Signaling Technology, C29G11) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig s1b) and in western blot on mouse samples at 1:250 (fig 3c). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (C29G11)
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...
Cell Signaling Technology Numb antibody (Cell Signaling, C29G11) was used in immunohistochemistry - frozen section on mouse samples at 1:400. Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (C29G11)
  • western blot; mouse; loading ...; fig 1f
Cell Signaling Technology Numb antibody (Cell signaling, 2756) was used in western blot on mouse samples (fig 1f). Cell Death Dis (2016) ncbi
domestic rabbit monoclonal (C29G11)
  • western blot; human
Cell Signaling Technology Numb antibody (Cell Signaling Technology, C29G11) was used in western blot on human samples . Cancer Res (2013) ncbi
Articles Reviewed
  1. Ianni A, Hofmann M, Kumari P, Tarighi S, Al tamari H, Görgens A, et al. Depletion of Numb and Numblike in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway. Front Cell Dev Biol. 2021;9:639162 pubmed publisher
  2. Chiremba T, Neufeld K. Constitutive Musashi1 expression impairs mouse postnatal development and intestinal homeostasis. Mol Biol Cell. 2021;32:28-44 pubmed publisher
  3. Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed publisher
  4. Lian W, Zhang L, Yang L, Chen W. AP-2α reverses vincristine-induced multidrug resistance of SGC7901 gastric cancer cells by inhibiting the Notch pathway. Apoptosis. 2017;22:933-941 pubmed publisher
  5. Lapierre L, Manning E, Mitchell K, Caldwell C, Goldenring J. Interaction of phosphorylated Rab11-FIP2 with Eps15 regulates apical junction composition. Mol Biol Cell. 2017;28:1088-1100 pubmed publisher
  6. Hirai M, Arita Y, McGlade C, Lee K, Chen J, Evans S. Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. J Clin Invest. 2017;127:569-582 pubmed publisher
  7. Dustrude E, Moutal A, Yang X, Wang Y, Khanna M, Khanna R. Hierarchical CRMP2 posttranslational modifications control NaV1.7 function. Proc Natl Acad Sci U S A. 2016;113:E8443-E8452 pubmed publisher
  8. Kuzmanov U, Guo H, Buchsbaum D, Cosme J, Abbasi C, Isserlin R, et al. Global phosphoproteomic profiling reveals perturbed signaling in a mouse model of dilated cardiomyopathy. Proc Natl Acad Sci U S A. 2016;113:12592-12597 pubmed
  9. Ju X, Hou Q, Sheng A, Wu K, Zhou Y, Jin Y, et al. The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice. elife. 2016;5: pubmed publisher
  10. Fujiwara T, Zhou J, Ye S, Zhao H. RNA-binding protein Musashi2 induced by RANKL is critical for osteoclast survival. Cell Death Dis. 2016;7:e2300 pubmed publisher
  11. Camps J, Pitt J, Emons G, Hummon A, Case C, Grade M, et al. Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer. Cancer Res. 2013;73:2003-13 pubmed publisher