This is a Validated Antibody Database (VAD) review about mouse Nr5a1, based on 10 published articles (read how Labome selects the articles), using Nr5a1 antibody in all methods. It is aimed to help Labome visitors find the most suited Nr5a1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Nr5a1 synonym: Ad4BP; ELP; ELP-3; Ftz-F1; Ftzf1; SF-1; SF1; STF-1

Invitrogen
mouse monoclonal (N1665)
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 1a
Invitrogen Nr5a1 antibody (Thermo Fisher Scientific, 434200) was used in immunohistochemistry - paraffin section on mouse samples at 1:300 (fig 1a). elife (2021) ncbi
mouse monoclonal (N1665)
  • immunohistochemistry; mouse; 1:200; loading ...; fig 5b
Invitrogen Nr5a1 antibody (Thermo Fisher Scientific, 434200) was used in immunohistochemistry on mouse samples at 1:200 (fig 5b). Development (2017) ncbi
mouse monoclonal (N1665)
  • immunohistochemistry; human; 1:200; fig 2a
In order to identify SAMD9 mutations in children with MIRAGE syndrome, Invitrogen Nr5a1 antibody (Invitrogen, N1665) was used in immunohistochemistry on human samples at 1:200 (fig 2a). J Clin Invest (2017) ncbi
mouse monoclonal (N1665)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...
In order to report the expression of senescence-associated lysosomal beta-galactosidase, p16, and p21 in different types of pituitary adenomas, Invitrogen Nr5a1 antibody (Invitrogen, N1665) was used in immunohistochemistry - paraffin section on human samples at 1:200. Endocr Pathol (2016) ncbi
mouse monoclonal (N1665)
  • immunohistochemistry - paraffin section; human; fig 6
In order to test if steroidogenic factor 1 is expressed in castration-resistant prostate cancer and determine if it stimulates aberrant steroidogenesis and fuels aggressive growth, Invitrogen Nr5a1 antibody (Invitrogen, N1665) was used in immunohistochemistry - paraffin section on human samples (fig 6). Endocrinology (2014) ncbi
mouse monoclonal (N1665)
  • immunohistochemistry - paraffin section; human; 1:100
In order to identify the origin of ovarian Brenner tumour, Invitrogen Nr5a1 antibody (Invitrogen, 434200) was used in immunohistochemistry - paraffin section on human samples at 1:100. Eur J Cancer (2013) ncbi
mouse monoclonal (N1665)
  • immunohistochemistry - paraffin section; human; fig 6
In order to study CYP19 over-expression in testicular Leydig cell tumors, Invitrogen Nr5a1 antibody (Invitrogen, MAB 434200) was used in immunohistochemistry - paraffin section on human samples (fig 6). Eur J Endocrinol (2012) ncbi
mouse monoclonal (N1665)
  • immunohistochemistry - frozen section; human; 1:200; fig 5
In order to identify Ang2 as a novel target of the nuclear receptor steroidogenic factor-1 in the adrenal gland, Invitrogen Nr5a1 antibody (Invitrogen, 434200) was used in immunohistochemistry - frozen section on human samples at 1:200 (fig 5). FASEB J (2011) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:300; loading ...; fig 3e
Abcam Nr5a1 antibody (Abcam, ab65815) was used in immunohistochemistry on mouse samples at 1:300 (fig 3e). Oncogene (2020) ncbi
domestic rabbit monoclonal
  • western blot; human; 1:2000; loading ...; fig 3d
Abcam Nr5a1 antibody (Abcam, ab168380) was used in western blot on human samples at 1:2000 (fig 3d). J Cell Mol Med (2019) ncbi
Articles Reviewed
  1. Russell J, Lim X, Santambrogio A, Yianni V, Kemkem Y, Wang B, et al. Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells. elife. 2021;10: pubmed publisher
  2. Borges K, Pignatti E, Leng S, Kariyawasam D, Ruiz Babot G, Ramalho F, et al. Wnt/β-catenin activation cooperates with loss of p53 to cause adrenocortical carcinoma in mice. Oncogene. 2020;39:5282-5291 pubmed publisher
  3. Huang H, Zou X, Zhong L, Hou Y, Zhou J, Zhang Z, et al. CRISPR/dCas9-mediated activation of multiple endogenous target genes directly converts human foreskin fibroblasts into Leydig-like cells. J Cell Mol Med. 2019;: pubmed publisher
  4. Haston S, Pozzi S, Carreno G, Manshaei S, Panousopoulos L, González Meljem J, et al. MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma. Development. 2017;144:2141-2152 pubmed publisher
  5. Buonocore F, Kühnen P, Suntharalingham J, Del Valle I, Digweed M, Stachelscheid H, et al. Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans. J Clin Invest. 2017;127:1700-1713 pubmed publisher
  6. Manojlović Gacić E, Skender Gazibara M, Popovic V, Soldatovic I, Boricic N, Raičević S, et al. Oncogene-Induced Senescence in Pituitary Adenomas--an Immunohistochemical Study. Endocr Pathol. 2016;27:1-11 pubmed publisher
  7. Lewis S, Hedman C, Ziegler T, Ricke W, Jorgensen J. Steroidogenic factor 1 promotes aggressive growth of castration-resistant prostate cancer cells by stimulating steroid synthesis and cell proliferation. Endocrinology. 2014;155:358-69 pubmed publisher
  8. Kuhn E, Ayhan A, Shih I, Seidman J, Kurman R. Ovarian Brenner tumour: a morphologic and immunohistochemical analysis suggesting an origin from fallopian tube epithelium. Eur J Cancer. 2013;49:3839-49 pubmed publisher
  9. Straume A, Løvås K, Miletic H, Gravdal K, Lønning P, Knappskog S. Elevated levels of the steroidogenic factor 1 are associated with over-expression of CYP19 in an oestrogen-producing testicular Leydig cell tumour. Eur J Endocrinol. 2012;166:941-9 pubmed publisher
  10. Ferraz de Souza B, Lin L, Shah S, Jina N, Hubank M, Dattani M, et al. ChIP-on-chip analysis reveals angiopoietin 2 (Ang2, ANGPT2) as a novel target of steroidogenic factor-1 (SF-1, NR5A1) in the human adrenal gland. FASEB J. 2011;25:1166-75 pubmed publisher