This is a Validated Antibody Database (VAD) review about mouse Npc2, based on 2 published articles (read how Labome selects the articles), using Npc2 antibody in all methods. It is aimed to help Labome visitors find the most suited Npc2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Npc2 synonym: 2700012J19Rik; AA408070; AU045843; HE1; NPC intracellular cholesterol transporter 2; Niemann-Pick type C2; epididymal secretory protein E1; mE1; niemann Pick type C2 protein homolog

Santa Cruz Biotechnology
mouse monoclonal (D-3)
  • immunocytochemistry; mouse; 1:50; fig 2
  • western blot; mouse; fig 2
In order to study a phosphoinositide-based mechanism that Arf6 uses to control retromer traffic and intracellular cholesterol distribution, Santa Cruz Biotechnology Npc2 antibody (Santa Cruz, sc-166449) was used in immunocytochemistry on mouse samples at 1:50 (fig 2) and in western blot on mouse samples (fig 2). Nat Commun (2016) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; loading ...; fig s10b
In order to discuss how signal peptidase complex proteins affect flaviviruses, Proteintech Group Npc2 antibody (Proteintech, 19888-1-AP) was used in western blot on human samples (fig s10b). Nature (2016) ncbi
Articles Reviewed
  1. Zhang R, Miner J, Gorman M, Rausch K, Ramage H, White J, et al. A CRISPR screen defines a signal peptide processing pathway required by flaviviruses. Nature. 2016;535:164-8 pubmed
  2. Marquer C, Tian H, Yi J, Bastien J, Dall Armi C, Yang Klingler Y, et al. Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism. Nat Commun. 2016;7:11919 pubmed publisher