This is a Validated Antibody Database (VAD) review about mouse Nlrp3, based on 47 published articles (read how Labome selects the articles), using Nlrp3 antibody in all methods. It is aimed to help Labome visitors find the most suited Nlrp3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Nlrp3 synonym: AGTAVPRL; AII/AVP; Cias1; FCAS; FCU; MWS; Mmig1; NALP3; Pypaf1

Knockout validation
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 5d
Abcam Nlrp3 antibody (Abcam, ab214185) was used in western blot knockout validation on mouse samples at 1:1000 (fig 5d). Int J Mol Med (2021) ncbi
Abcam
domestic goat polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 4a
Abcam Nlrp3 antibody (Abcam, ab4207) was used in western blot knockout validation on mouse samples at 1:1000 (fig 4a). Behav Brain Res (2017) ncbi
Adipogen
mouse monoclonal (Cryo-2)
  • western blot knockout validation; mouse; fig 4
Adipogen Nlrp3 antibody (AdipoGen, cryo-2) was used in western blot knockout validation on mouse samples (fig 4). Nat Immunol (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR23094-1)
  • western blot; rat; 1:1000; loading ...; fig 4b
Abcam Nlrp3 antibody (Abcam, ab263899) was used in western blot on rat samples at 1:1000 (fig 4b). Front Pharmacol (2021) ncbi
domestic rabbit monoclonal (EPR23094-1)
  • western blot; mouse; 1:1000; loading ...; fig 4d
Abcam Nlrp3 antibody (Abcam, 263899) was used in western blot on mouse samples at 1:1000 (fig 4d). J Neuroinflammation (2021) ncbi
domestic rabbit monoclonal (EPR23094-1)
  • immunohistochemistry; mouse; 1:200; fig 5c
Abcam Nlrp3 antibody (Abcam, Ab263899) was used in immunohistochemistry on mouse samples at 1:200 (fig 5c). J Cell Mol Med (2021) ncbi
domestic goat polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 2c
Abcam Nlrp3 antibody (Abcam, ab4207) was used in immunohistochemistry on mouse samples at 1:200 (fig 2c). J Inflamm Res (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 5d
Abcam Nlrp3 antibody (Abcam, ab214185) was used in western blot knockout validation on mouse samples at 1:1000 (fig 5d). Int J Mol Med (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200
Abcam Nlrp3 antibody (Abcam, ab214185) was used in immunohistochemistry on mouse samples at 1:200. Aging Cell (2021) ncbi
domestic goat polyclonal
  • immunocytochemistry; human; 1:100; loading ...; fig 1b
Abcam Nlrp3 antibody (Abcam, ab4207) was used in immunocytochemistry on human samples at 1:100 (fig 1b). Science (2020) ncbi
domestic goat polyclonal
  • immunocytochemistry; rat; 1:200; loading ...; fig 3i
Abcam Nlrp3 antibody (Abcam, ab4207) was used in immunocytochemistry on rat samples at 1:200 (fig 3i). Bone Res (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 8
  • western blot; mouse; 1:1000; loading ...; fig 7a
Abcam Nlrp3 antibody (Abcam, ab214185) was used in immunohistochemistry on mouse samples at 1:200 (fig 8) and in western blot on mouse samples at 1:1000 (fig 7a). J Transl Med (2020) ncbi
domestic goat polyclonal
  • immunohistochemistry - frozen section; rat; 1:200; loading ...; fig 2d
Abcam Nlrp3 antibody (Abcam, ab4207) was used in immunohistochemistry - frozen section on rat samples at 1:200 (fig 2d). Front Neurosci (2019) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:500; loading ...; fig 7a
Abcam Nlrp3 antibody (Abcam, ab214185) was used in western blot on rat samples at 1:500 (fig 7a). Oxid Med Cell Longev (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 1c
Abcam Nlrp3 antibody (abcam, ab214185) was used in western blot on human samples at 1:500 (fig 1c). BMC Cardiovasc Disord (2019) ncbi
domestic goat polyclonal
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3d
Abcam Nlrp3 antibody (Abcam, ab4207) was used in immunohistochemistry - paraffin section on mouse samples (fig 3d). Front Immunol (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4h
Abcam Nlrp3 antibody (Abcam, ab214185) was used in western blot on human samples (fig 4h). Aging (Albany NY) (2019) ncbi
domestic goat polyclonal
  • proximity ligation assay; mouse; loading ...; fig 3b
Abcam Nlrp3 antibody (Abcam, ab4207) was used in proximity ligation assay on mouse samples (fig 3b). Cell Death Dis (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 11b
Abcam Nlrp3 antibody (Abcam, ab214185) was used in western blot on mouse samples at 1:1000 (fig 11b). Int J Mol Med (2018) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:500; loading ...; fig 5c
Abcam Nlrp3 antibody (Abcam, ab214185) was used in western blot on rat samples at 1:500 (fig 5c). Stroke (2018) ncbi
domestic goat polyclonal
  • western blot; mouse; 1:500; loading ...; fig 4c
Abcam Nlrp3 antibody (Abcam, ab4207) was used in western blot on mouse samples at 1:500 (fig 4c). Clin Sci (Lond) (2017) ncbi
domestic goat polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 4a
Abcam Nlrp3 antibody (Abcam, ab4207) was used in western blot knockout validation on mouse samples at 1:1000 (fig 4a). Behav Brain Res (2017) ncbi
domestic goat polyclonal
  • immunocytochemistry; human; 1:100; loading ...; fig 5a
  • western blot; human; loading ...; fig 1a
Abcam Nlrp3 antibody (Abcam, ab4207) was used in immunocytochemistry on human samples at 1:100 (fig 5a) and in western blot on human samples (fig 1a). Pharmacol Res (2017) ncbi
domestic goat polyclonal
  • western blot; mouse; loading ...; fig 8
Abcam Nlrp3 antibody (Abcam, ab4207) was used in western blot on mouse samples (fig 8). Cell Death Dis (2016) ncbi
domestic goat polyclonal
  • western blot; mouse; loading ...; fig 4C
In order to examine the thymic microenvironment using a model of paracoccidioidomycosis, Abcam Nlrp3 antibody (Abcam, ab4207) was used in western blot on mouse samples (fig 4C). PLoS ONE (2016) ncbi
domestic goat polyclonal
  • western blot; mouse; loading ...; fig 6a
In order to investigate the contribution of NLRP3 inflammasome activity to the T helper cell 1 response, Abcam Nlrp3 antibody (Abcam, ab4207) was used in western blot on mouse samples (fig 6a). Science (2016) ncbi
Novus Biologicals
domestic rabbit polyclonal (14C8)
Novus Biologicals Nlrp3 antibody (Novus, NBP1-77080) was used . J Neuroinflammation (2015) ncbi
Adipogen
mouse monoclonal (Cryo-2)
  • western blot; mouse; fig 1k
  • western blot; human; loading ...; fig 2e
Adipogen Nlrp3 antibody (AdipoGen Life Sciences, AG-20B-0014-C100) was used in western blot on mouse samples (fig 1k) and in western blot on human samples (fig 2e). Cell Death Dis (2021) ncbi
mouse monoclonal (Cryo-2)
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig s1a
Adipogen Nlrp3 antibody (AdipoGen, AG-20B-0014-C100) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig s1a). Sci Adv (2020) ncbi
mouse monoclonal (Cryo-2)
  • western blot; mouse; loading ...; fig 3e
Adipogen Nlrp3 antibody (AdipoGen, Cryo-2) was used in western blot on mouse samples (fig 3e). Sci Rep (2020) ncbi
mouse monoclonal (Cryo-2)
  • western blot; mouse; 1:1000; loading ...; fig 2f
Adipogen Nlrp3 antibody (AdipoGen Life Sciences, AG-20B-0014-C100) was used in western blot on mouse samples at 1:1000 (fig 2f). Sci Rep (2020) ncbi
mouse monoclonal (Cryo-2)
  • western blot; mouse; 1:1000; loading ...; fig st6
Adipogen Nlrp3 antibody (Adipogen, AG-20B-0014-C100) was used in western blot on mouse samples at 1:1000 (fig st6). Sci Rep (2020) ncbi
mouse monoclonal (Cryo-2)
  • western blot; human; 1:1000; loading ...; fig 1b
  • western blot; mouse; 1:1000; loading ...; fig 2c
Adipogen Nlrp3 antibody (AdipoGen, AG-20B-0014-C100) was used in western blot on human samples at 1:1000 (fig 1b) and in western blot on mouse samples at 1:1000 (fig 2c). Cell Mol Gastroenterol Hepatol (2020) ncbi
mouse monoclonal (Cryo-2)
  • proximity ligation assay; mouse; loading ...; fig 3b
  • western blot; mouse; loading ...; fig s3e
Adipogen Nlrp3 antibody (Adipogen, Cryo-2) was used in proximity ligation assay on mouse samples (fig 3b) and in western blot on mouse samples (fig s3e). Cell Death Dis (2019) ncbi
mouse monoclonal (Cryo-2)
  • western blot; human; loading ...; fig 1d
Adipogen Nlrp3 antibody (Adipogen, AG-20B-0014-C100) was used in western blot on human samples (fig 1d). Nature (2019) ncbi
mouse monoclonal (Cryo-2)
  • western blot; human; loading ...; fig s3f
Adipogen Nlrp3 antibody (Adipogen, Cryo-2) was used in western blot on human samples (fig s3f). Nat Immunol (2019) ncbi
mouse monoclonal (Cryo-2)
  • western blot; mouse; loading ...; fig 1b
Adipogen Nlrp3 antibody (Adipogen, AG-20B-0014-C100) was used in western blot on mouse samples (fig 1b). Sci Adv (2019) ncbi
mouse monoclonal (Cryo-2)
  • western blot; mouse; loading ...; fig 2k
Adipogen Nlrp3 antibody (AdipoGen, AG-20B-0014-C100) was used in western blot on mouse samples (fig 2k). Cell Mol Gastroenterol Hepatol (2019) ncbi
mouse monoclonal (Cryo-2)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 7a
  • western blot; mouse; 1:2000; loading ...; fig 1d
Adipogen Nlrp3 antibody (AdipoGen, AG-20B-0014-C100) was used in immunohistochemistry on mouse samples at 1:1000 (fig 7a) and in western blot on mouse samples at 1:2000 (fig 1d). J Cell Biol (2018) ncbi
mouse monoclonal (Cryo-2)
  • western blot; human; loading ...; fig s16b
Adipogen Nlrp3 antibody (Adipogen, CRYO-2) was used in western blot on human samples (fig s16b). J Clin Invest (2018) ncbi
mouse monoclonal (Cryo-2)
  • western blot; human; 1:500; fig 2b
Adipogen Nlrp3 antibody (Adipogen, Cryo-2) was used in western blot on human samples at 1:500 (fig 2b). Nat Commun (2018) ncbi
mouse monoclonal (Cryo-2)
  • western blot; mouse; loading ...; fig s17b
Adipogen Nlrp3 antibody (AdipoGen Life Sciences, Cryo-2) was used in western blot on mouse samples (fig s17b). Science (2017) ncbi
mouse monoclonal (Cryo-2)
  • immunoprecipitation; human; loading ...; fig 3c
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6c
  • immunoprecipitation; mouse; loading ...; fig 3g
  • western blot; mouse; loading ...; fig 5c
Adipogen Nlrp3 antibody (Adipogen, (AG-20B-0014-C100) was used in immunoprecipitation on human samples (fig 3c), in immunohistochemistry - paraffin section on mouse samples (fig 6c), in immunoprecipitation on mouse samples (fig 3g) and in western blot on mouse samples (fig 5c). Cell Death Dis (2016) ncbi
mouse monoclonal (Cryo-2)
  • immunocytochemistry; human; fig s5
In order to investigate the role of IL-1beta/caspase-1 signaling in bleomycin lung toxicity and in pleural mesothelial cell transformation, Adipogen Nlrp3 antibody (Adipogen, Cryo-2) was used in immunocytochemistry on human samples (fig s5). Respir Res (2016) ncbi
mouse monoclonal (Cryo-2)
  • EMSA; human; fig 5g
  • immunoprecipitation; human; fig s8c
  • immunocytochemistry; human; 1:100; fig 5a
  • western blot; human; 1:1000; fig 5e
In order to discuss clinical studies approved by the Human Ethics Committee at Lund University, Adipogen Nlrp3 antibody (Adipogen, AG-20B-0014-C100) was used in EMSA on human samples (fig 5g), in immunoprecipitation on human samples (fig s8c), in immunocytochemistry on human samples at 1:100 (fig 5a) and in western blot on human samples at 1:1000 (fig 5e). PLoS Pathog (2016) ncbi
mouse monoclonal (Cryo-2)
  • western blot; mouse; 1:1000; loading ...; fig 1d
  • western blot; human; 1:1000; loading ...; fig 6i
Adipogen Nlrp3 antibody (Adipogen, Cryo-2) was used in western blot on mouse samples at 1:1000 (fig 1d) and in western blot on human samples at 1:1000 (fig 6i). Nat Immunol (2016) ncbi
mouse monoclonal (Cryo-2)
  • flow cytometry; human; loading ...; fig 2d
  • immunocytochemistry; human; loading ...; fig 1e
In order to investigate the contribution of NLRP3 inflammasome activity to the T helper cell 1 response, Adipogen Nlrp3 antibody (Adipogen, AG-20B-0014-C100) was used in flow cytometry on human samples (fig 2d) and in immunocytochemistry on human samples (fig 1e). Science (2016) ncbi
mouse monoclonal (Cryo-2)
  • immunoprecipitation; human; fig 1
  • western blot; human; fig 1
Adipogen Nlrp3 antibody (AdipoGen2, Cryo-2) was used in immunoprecipitation on human samples (fig 1) and in western blot on human samples (fig 1). Nature (2016) ncbi
mouse monoclonal (Cryo-2)
  • western blot knockout validation; mouse; fig 4
Adipogen Nlrp3 antibody (AdipoGen, cryo-2) was used in western blot knockout validation on mouse samples (fig 4). Nat Immunol (2016) ncbi
mouse monoclonal (Cryo-2)
  • western blot; mouse; loading ...; fig s6a
Adipogen Nlrp3 antibody (AdipoGen, Cryo-2) was used in western blot on mouse samples (fig s6a). Nature (2015) ncbi
mouse monoclonal (Cryo-2)
  • immunoprecipitation; human; loading ...; fig 1e
  • western blot; human; loading ...; fig 1e
Adipogen Nlrp3 antibody (Adipogen, cryo-2) was used in immunoprecipitation on human samples (fig 1e) and in western blot on human samples (fig 1e). J Biol Chem (2014) ncbi
mouse monoclonal (Cryo-2)
  • western blot; human; loading ...; fig 3a
Adipogen Nlrp3 antibody (AdipoGen, Cryo-2) was used in western blot on human samples (fig 3a). Innate Immun (2015) ncbi
Articles Reviewed
  1. Zheng J, Yao L, Zhou Y, Gu X, Wang C, Bao K, et al. A novel function of NLRP3 independent of inflammasome as a key transcription factor of IL-33 in epithelial cells of atopic dermatitis. Cell Death Dis. 2021;12:871 pubmed publisher
  2. Kong L, Zhang H, Lu C, Shi K, Huang H, Zheng Y, et al. AICAR, an AMP-Activated Protein Kinase Activator, Ameliorates Acute Pancreatitis-Associated Liver Injury Partially Through Nrf2-Mediated Antioxidant Effects and Inhibition of NLRP3 Inflammasome Activation. Front Pharmacol. 2021;12:724514 pubmed publisher
  3. Zeng H, Chen H, Li M, Zhuang J, Peng Y, Zhou H, et al. Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH. J Neuroinflammation. 2021;18:210 pubmed publisher
  4. Cheng C, Xue F, Sui W, Meng L, Xie L, Zhang C, et al. Deletion of natriuretic peptide receptor C alleviates adipose tissue inflammation in hypercholesterolemic Apolipoprotein E knockout mice. J Cell Mol Med. 2021;25:9837-9850 pubmed publisher
  5. Zou Y, Bhat O, Yuan X, Li G, Huang D, Guo Y, et al. Release and Actions of Inflammatory Exosomes in Pulmonary Emphysema: Potential Therapeutic Target of Acupuncture. J Inflamm Res. 2021;14:3501-3521 pubmed publisher
  6. Zhao J, Chen J, Li Y, Xia L, Wu Y. Bruton's tyrosine kinase regulates macrophage‑induced inflammation in the diabetic kidney via NLRP3 inflammasome activation. Int J Mol Med. 2021;48: pubmed publisher
  7. Poudel S, Dixit M, Yildirim G, Cordoba Chacon J, Gahete M, Yuji I, et al. Sexual dimorphic impact of adult-onset somatopause on life span and age-induced osteoarthritis. Aging Cell. 2021;20:e13427 pubmed publisher
  8. Zhang X, Wang R, Hu D, Sun X, Fujioka H, Lundberg K, et al. Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease. Sci Adv. 2020;6: pubmed publisher
  9. Magupalli V, Negro R, Tian Y, Hauenstein A, Di Caprio G, Skillern W, et al. HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation. Science. 2020;369: pubmed publisher
  10. Kim Y, Kim J, Gu S, Jo S, Kim S, Young Kim S, et al. Identification of highly potent and selective inhibitor, TIPTP, of the p22phox-Rubicon axis as a therapeutic agent for rheumatoid arthritis. Sci Rep. 2020;10:4570 pubmed publisher
  11. Chen F, Jiang G, Liu H, Li Z, Pei Y, Wang H, et al. Melatonin alleviates intervertebral disc degeneration by disrupting the IL-1β/NF-κB-NLRP3 inflammasome positive feedback loop. Bone Res. 2020;8:10 pubmed publisher
  12. Gao Y, Dai X, Li Y, Li G, Lin X, Ai C, et al. Role of Parkin-mediated mitophagy in the protective effect of polydatin in sepsis-induced acute kidney injury. J Transl Med. 2020;18:114 pubmed publisher
  13. Wooff Y, Fernando N, Wong J, Dietrich C, Aggio Bruce R, Chu Tan J, et al. Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration. Sci Rep. 2020;10:2263 pubmed publisher
  14. Zhuang K, Zuo Y, Sherchan P, Wang J, Yan X, Liu F. Hydrogen Inhalation Attenuates Oxidative Stress Related Endothelial Cells Injury After Subarachnoid Hemorrhage in Rats. Front Neurosci. 2019;13:1441 pubmed publisher
  15. Yu J, Wang W, Matei N, Li X, Pang J, Mo J, et al. Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats. Oxid Med Cell Longev. 2020;2020:4717258 pubmed publisher
  16. Svensson M, Andersson E, Manouchehrian O, Yang Y, Deierborg T. Voluntary running does not reduce neuroinflammation or improve non-cognitive behavior in the 5xFAD mouse model of Alzheimer's disease. Sci Rep. 2020;10:1346 pubmed publisher
  17. Cai S, Ge M, Mennone A, Hoque R, Ouyang X, Boyer J. Inflammasome Is Activated in the Liver of Cholestatic Patients and Aggravates Hepatic Injury in Bile Duct-Ligated Mouse. Cell Mol Gastroenterol Hepatol. 2020;9:679-688 pubmed publisher
  18. Liu Y, Tie L. Apolipoprotein M and sphingosine-1-phosphate complex alleviates TNF-α-induced endothelial cell injury and inflammation through PI3K/AKT signaling pathway. BMC Cardiovasc Disord. 2019;19:279 pubmed publisher
  19. Borghi M, Pariano M, Solito V, Puccetti M, Bellet M, Stincardini C, et al. Targeting the Aryl Hydrocarbon Receptor With Indole-3-Aldehyde Protects From Vulvovaginal Candidiasis via the IL-22-IL-18 Cross-Talk. Front Immunol. 2019;10:2364 pubmed publisher
  20. Liu J, Yao L, Zhang M, Jiang J, Yang M, Wang Y. Downregulation of LncRNA-XIST inhibited development of non-small cell lung cancer by activating miR-335/SOD2/ROS signal pathway mediated pyroptotic cell death. Aging (Albany NY). 2019;11:7830-7846 pubmed publisher
  21. Dumont A, de Rosny C, Kieu T, Perrey S, Berger H, Fluckiger A, et al. Docosahexaenoic acid inhibits both NLRP3 inflammasome assembly and JNK-mediated mature IL-1β secretion in 5-fluorouracil-treated MDSC: implication in cancer treatment. Cell Death Dis. 2019;10:485 pubmed publisher
  22. Sharif H, Wang L, Wang W, Magupalli V, Andreeva L, Qiao Q, et al. Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome. Nature. 2019;: pubmed publisher
  23. Choi Y, Kim S, Choi Y, Nielsen T, Yan J, Lu A, et al. SERPINB1-mediated checkpoint of inflammatory caspase activation. Nat Immunol. 2019;20:276-287 pubmed publisher
  24. Huang X, Feng Z, Jiang Y, Li J, Xiang Q, Guo S, et al. VSIG4 mediates transcriptional inhibition of Nlrp3 and Il-1β in macrophages. Sci Adv. 2019;5:eaau7426 pubmed publisher
  25. Kiyohara H, Sujino T, Teratani T, Miyamoto K, Arai M, Nomura E, et al. Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells. Cell Mol Gastroenterol Hepatol. 2019;7:135-156 pubmed publisher
  26. de la Roche M, Hamilton C, Mortensen R, Jeyaprakash A, Ghosh S, Anand P. Trafficking of cholesterol to the ER is required for NLRP3 inflammasome activation. J Cell Biol. 2018;217:3560-3576 pubmed publisher
  27. Lau A, Chung H, Komada T, Platnich J, Sandall C, Choudhury S, et al. Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury. J Clin Invest. 2018;128:2894-2913 pubmed publisher
  28. Song H, Li X, Liu Y, Lu W, Cui Z, Zhou L, et al. Carnosic acid protects mice from high-fat diet-induced NAFLD by regulating MARCKS. Int J Mol Med. 2018;42:193-207 pubmed publisher
  29. Lagrange B, Benaoudia S, Wallet P, Magnotti F, Provost A, Michal F, et al. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11. Nat Commun. 2018;9:242 pubmed publisher
  30. Zhou K, Enkhjargal B, Xie Z, Sun C, Wu L, Malaguit J, et al. Dihydrolipoic Acid Inhibits Lysosomal Rupture and NLRP3 Through Lysosome-Associated Membrane Protein-1/Calcium/Calmodulin-Dependent Protein Kinase II/TAK1 Pathways After Subarachnoid Hemorrhage in Rat. Stroke. 2018;49:175-183 pubmed publisher
  31. Fuster J, MacLauchlan S, Zuriaga M, Polackal M, Ostriker A, Chakraborty R, et al. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice. Science. 2017;355:842-847 pubmed publisher
  32. Irrera N, Vaccaro M, Bitto A, Pallio G, Pizzino G, Lentini M, et al. BAY 11-7082 inhibits the NF-?B and NLRP3 inflammasome pathways and protects against IMQ-induced psoriasis. Clin Sci (Lond). 2017;131:487-498 pubmed publisher
  33. Su W, Zhang Y, Chen Y, Gong H, Lian Y, Peng W, et al. NLRP3 gene knockout blocks NF-?B and MAPK signaling pathway in CUMS-induced depression mouse model. Behav Brain Res. 2017;322:1-8 pubmed publisher
  34. Jiang S, Zhang Y, Zheng J, Li X, Yao Y, Wu Y, et al. Potentiation of hepatic stellate cell activation by extracellular ATP is dependent on P2X7R-mediated NLRP3 inflammasome activation. Pharmacol Res. 2017;117:82-93 pubmed publisher
  35. Wei C, Wang Y, Du Z, Guan K, Cao Y, Yang H, et al. The Yersinia Type III secretion effector YopM Is an E3 ubiquitin ligase that induced necrotic cell death by targeting NLRP3. Cell Death Dis. 2016;7:e2519 pubmed publisher
  36. Burgy O, Bellaye P, Causse S, Beltramo G, Wettstein G, Boutanquoi P, et al. Pleural inhibition of the caspase-1/IL-1? pathway diminishes profibrotic lung toxicity of bleomycin. Respir Res. 2016;17:162 pubmed
  37. Hu Z, Zhang Y, Wang J, Mao P, Lv X, Yuan S, et al. Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light. Cell Death Dis. 2016;7:e2468 pubmed publisher
  38. Alves da Costa T, Di Gangi R, Thomé R, Barreto Felisbino M, Pires Bonfanti A, Lumi Watanabe Ishikawa L, et al. Severe Changes in Thymic Microenvironment in a Chronic Experimental Model of Paracoccidioidomycosis. PLoS ONE. 2016;11:e0164745 pubmed publisher
  39. Ambite I, Puthia M, Nagy K, Cafaro C, Nadeem A, Butler D, et al. Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets. PLoS Pathog. 2016;12:e1005848 pubmed publisher
  40. Mortimer L, Moreau F, MacDonald J, Chadee K. NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations. Nat Immunol. 2016;17:1176-86 pubmed publisher
  41. Arbore G, West E, Spolski R, Robertson A, Klos A, Rheinheimer C, et al. T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells. Science. 2016;352:aad1210 pubmed publisher
  42. He Y, Zeng M, Yang D, Motro B, Núñez G. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux. Nature. 2016;530:354-7 pubmed publisher
  43. Shi H, Wang Y, Li X, Zhan X, Tang M, Fina M, et al. NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component. Nat Immunol. 2016;17:250-8 pubmed publisher
  44. Kayagaki N, Stowe I, Lee B, O Rourke K, Anderson K, Warming S, et al. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature. 2015;526:666-71 pubmed publisher
  45. Chi W, Chen H, Li F, Zhu Y, Yin W, Zhuo Y. HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma. J Neuroinflammation. 2015;12:137 pubmed publisher
  46. Giguère P, Gall B, Ezekwe E, Laroche G, Buckley B, Kebaier C, et al. G Protein signaling modulator-3 inhibits the inflammasome activity of NLRP3. J Biol Chem. 2014;289:33245-57 pubmed publisher
  47. Huck O, Elkaim R, Davideau J, Tenenbaum H. Porphyromonas gingivalis-impaired innate immune response via NLRP3 proteolysis in endothelial cells. Innate Immun. 2015;21:65-72 pubmed publisher