This is a Validated Antibody Database (VAD) review about mouse Nkx2-1, based on 36 published articles (read how Labome selects the articles), using Nkx2-1 antibody in all methods. It is aimed to help Labome visitors find the most suited Nkx2-1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Nkx2-1 synonym: AV026640; Nkx2.1; T/EBP; Titf1; Ttf-1

Abcam
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s5d
Abcam Nkx2-1 antibody (Abcam, 76013) was used in immunohistochemistry - paraffin section on mouse samples (fig s5d). Sci Adv (2022) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 4b
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry - frozen section on mouse samples (fig 4b). Sci Adv (2022) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - frozen section; African green monkey; 1:200-1:2000; loading ...; fig 4b
Abcam Nkx2-1 antibody (Abcam, AB76013) was used in immunohistochemistry - frozen section on African green monkey samples at 1:200-1:2000 (fig 4b). Sci Adv (2022) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s1b
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s1b). Nat Commun (2021) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry; mouse; 1:250; loading ...; fig 4e
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry on mouse samples at 1:250 (fig 4e). Genes Dev (2021) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry; human; 1:250; loading ...; fig s7c
Abcam Nkx2-1 antibody (abcam, ab76013) was used in immunohistochemistry on human samples at 1:250 (fig s7c). Genome Biol (2021) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry; mouse; 1:2000; loading ...; fig 1a
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry on mouse samples at 1:2000 (fig 1a). elife (2021) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig e2f
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig e2f). Nature (2021) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig s2a
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig s2a). Nat Commun (2020) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 1f, 4c
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 1f, 4c). Nat Commun (2020) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 6d
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry - paraffin section on mouse samples at 1:300 (fig 6d). Nat Commun (2019) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - paraffin section; mouse; 1:250; loading ...; fig 7b
  • immunoprecipitation; mouse; ; loading ...; fig 7f
  • western blot; mouse; 1:1000; loading ...; fig 7e
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry - paraffin section on mouse samples at 1:250 (fig 7b), in immunoprecipitation on mouse samples at (fig 7f) and in western blot on mouse samples at 1:1000 (fig 7e). elife (2019) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s1l
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s1l). Cell (2019) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry; mouse; loading ...; fig 4d
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry on mouse samples (fig 4d). Nature (2019) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry; mouse; 1:250
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry on mouse samples at 1:250. elife (2019) ncbi
domestic rabbit monoclonal (EP1584Y)
  • western blot; human; 1:2000; loading ...; fig s4h
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in western blot on human samples at 1:2000 (fig s4h). Immunity (2018) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry; mouse; loading ...; fig 2c
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry on mouse samples (fig 2c). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (EP1584Y)
  • other; human; loading ...; fig 4c
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s3e
Abcam Nkx2-1 antibody (Abcam, EP1584Y) was used in immunohistochemistry - paraffin section on mouse samples (fig s3e). Cell (2017) ncbi
domestic rabbit monoclonal (EP1584Y)
  • western blot; mouse; loading ...; fig 8i
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in western blot on mouse samples (fig 8i). J Cell Biol (2017) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig s5a
Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry - paraffin section on mouse samples at 1:400 (fig s5a). Proc Natl Acad Sci U S A (2017) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunocytochemistry; human; fig 2e
In order to study the contribution of Wnt signaling to the development of functional proximal airway organoids, Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunocytochemistry on human samples (fig 2e). Cell Stem Cell (2017) ncbi
domestic rabbit monoclonal (EP1584Y)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Abcam Nkx2-1 antibody (Abcam, ab76013) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig st14
In order to outline the protocols for antibodies used for immunohistochemical studies, Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig st14). J Toxicol Pathol (2017) ncbi
domestic rabbit monoclonal (EP1584Y)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Abcam Nkx2-1 antibody (Abcam, ab76013) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry - free floating section; mouse; 1:2000; loading ...; fig 1e
In order to develop a recombinant adeno-associated virus that restricts gene expression to GABAergic interneurons within the telencephalon, Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry - free floating section on mouse samples at 1:2000 (fig 1e). Nat Neurosci (2016) ncbi
domestic rabbit monoclonal (EP1584Y)
  • immunohistochemistry; human; 1:200; fig 3S2A
In order to find that human lung organoids require a bioartificial microporous poly(lactide-co-glycolide) scaffold niche for successful engraftment, long-term survival, and maturation of lung epithelium in vivo, Abcam Nkx2-1 antibody (Abcam, ab76013) was used in immunohistochemistry on human samples at 1:200 (fig 3S2A). elife (2016) ncbi
domestic rabbit monoclonal (EPR8190-6)
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig 1
In order to characterize the spontaneous peripheral squamous cell lung cancer in mice by ablation of liver X receptors alpha and beta, Abcam Nkx2-1 antibody (Abcam, ab133638) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 1). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (EPR8190-6)
  • immunohistochemistry - frozen section; domestic rabbit
Abcam Nkx2-1 antibody (Abcam, ab133638) was used in immunohistochemistry - frozen section on domestic rabbit samples . Neuroscience (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (8G7G3/1)
  • western blot; human; loading ...; fig 4d
Santa Cruz Biotechnology Nkx2-1 antibody (Santa Cruz, sc-53136) was used in western blot on human samples (fig 4d). J Pathol Clin Res (2021) ncbi
mouse monoclonal (8G7G3/1)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1f
Santa Cruz Biotechnology Nkx2-1 antibody (Santa Cruz, sc-53136) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1f). Nat Commun (2021) ncbi
mouse monoclonal (8G7G3/1)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 3a
Santa Cruz Biotechnology Nkx2-1 antibody (Santa Cruz, sc-53136) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 3a). Medicine (Baltimore) (2020) ncbi
mouse monoclonal (8G7G3/1)
  • chromatin immunoprecipitation; human; fig 2
  • western blot; human; fig 1
Santa Cruz Biotechnology Nkx2-1 antibody (Santa Cruz, sc-53136) was used in chromatin immunoprecipitation on human samples (fig 2) and in western blot on human samples (fig 1). Oncotarget (2015) ncbi
mouse monoclonal (8G7G3/1)
  • immunohistochemistry - paraffin section; human
In order to develop a 3D lung model using human bronchial epithelial cells, Santa Cruz Biotechnology Nkx2-1 antibody (Santa Cruz, 8G7G3/1) was used in immunohistochemistry - paraffin section on human samples . Differentiation (2014) ncbi
mouse monoclonal (8G7G3/1)
  • immunohistochemistry - paraffin section; mouse; 1:200
Santa Cruz Biotechnology Nkx2-1 antibody (Santa Cruz Biotechnology, SC-53136) was used in immunohistochemistry - paraffin section on mouse samples at 1:200. Stem Cells Transl Med (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D2E8)
  • immunohistochemistry; mouse; 1:50; fig 3
In order to study the role of Cdc42 in foregut development and organ bud formation, Cell Signaling Technology Nkx2-1 antibody (Cell Signaling, 12373) was used in immunohistochemistry on mouse samples at 1:50 (fig 3). Biol Open (2016) ncbi
Articles Reviewed
  1. Werder R, Liu T, Abo K, Lindstrom Vautrin J, Villacorta Martin C, Huang J, et al. CRISPR interference interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells. Sci Adv. 2022;8:eabo6566 pubmed publisher
  2. Yu D, Li T, Delpech J, Zhu B, Kishore P, Koshi T, et al. Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits. Sci Adv. 2022;8:eabm2545 pubmed publisher
  3. Zhu X, Guo Y, Chu C, Liu D, Duan K, Yin Y, et al. BRN2 as a key gene drives the early primate telencephalon development. Sci Adv. 2022;8:eabl7263 pubmed publisher
  4. Tan X, Tong L, Li L, Xu J, Xie S, Ji L, et al. Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation. Nat Commun. 2021;12:4853 pubmed publisher
  5. Olsen R, Ireland A, Kastner D, Groves S, Spainhower K, Pozo K, et al. ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer. Genes Dev. 2021;35:847-869 pubmed publisher
  6. Sano K, Hayashi T, Suehara Y, Hosoya M, Takamochi K, Kohsaka S, et al. Transcription start site-level expression of thyroid transcription factor 1 isoforms in lung adenocarcinoma and its clinicopathological significance. J Pathol Clin Res. 2021;7:361-374 pubmed publisher
  7. Yuan C, Chen H, Tu S, Huang H, Pan Y, Gui X, et al. A systematic dissection of the epigenomic heterogeneity of lung adenocarcinoma reveals two different subclasses with distinct prognosis and core regulatory networks. Genome Biol. 2021;22:156 pubmed publisher
  8. Zewdu R, Mehrabad E, Ingram K, Fang P, Gillis K, Camolotto S, et al. An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. elife. 2021;10: pubmed publisher
  9. Yuan G, Flores N, Hausmann S, Lofgren S, Kharchenko V, Angulo Ibáñez M, et al. Elevated NSD3 histone methylation activity drives squamous cell lung cancer. Nature. 2021;590:504-508 pubmed publisher
  10. Vaughan C, Singh S, Subler M, Windle J, Inoue K, Fry E, et al. The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3. Nat Commun. 2021;12:704 pubmed publisher
  11. Soleilhavoup C, Travaglio M, Patrick K, Garção P, Boobalan E, Adolfs Y, et al. Nolz1 expression is required in dopaminergic axon guidance and striatal innervation. Nat Commun. 2020;11:3111 pubmed publisher
  12. Liu Z, Chen S, Xu Y, Liu X, Xiong P, Fu Y. Surfactant protein A expression and distribution in human lung samples from smokers with or without chronic obstructive pulmonary disease in China. Medicine (Baltimore). 2020;99:e19118 pubmed publisher
  13. Ikonomou L, Herriges M, Lewandowski S, Marsland R, Villacorta Martin C, Caballero I, et al. The in vivo genetic program of murine primordial lung epithelial progenitors. Nat Commun. 2020;11:635 pubmed publisher
  14. Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, et al. A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice. Nat Commun. 2019;10:5681 pubmed publisher
  15. van Veen J, Scherzer M, Boshuizen J, Chu M, Liu A, Landman A, et al. Mutationally-activated PI3'-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase. elife. 2019;8: pubmed publisher
  16. Wiel C, Le Gal K, Ibrahim M, Jahangir C, Kashif M, Yao H, et al. BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis. Cell. 2019;: pubmed publisher
  17. Walter D, Yates T, Ruiz Torres M, Kim Kiselak C, Gudiel A, Deshpande C, et al. RB constrains lineage fidelity and multiple stages of tumour progression and metastasis. Nature. 2019;569:423-427 pubmed publisher
  18. Lesch B, Tothova Z, Morgan E, Liao Z, Bronson R, Ebert B, et al. Intergenerational epigenetic inheritance of cancer susceptibility in mammals. elife. 2019;8: pubmed publisher
  19. Mollaoglu G, Jones A, Wait S, Mukhopadhyay A, Jeong S, Arya R, et al. The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment. Immunity. 2018;49:764-779.e9 pubmed publisher
  20. Wang B, Joo J, Mount R, Teubner B, Krenzer A, Ward A, et al. The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018;128:3319-3332 pubmed publisher
  21. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  22. Kortlever R, Sodir N, Wilson C, Burkhart D, Pellegrinet L, Brown Swigart L, et al. Myc Cooperates with Ras by Programming Inflammation and Immune Suppression. Cell. 2017;171:1301-1315.e14 pubmed publisher
  23. Yao J, Guihard P, Wu X, Blázquez Medela A, Spencer M, Jumabay M, et al. Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. J Cell Biol. 2017;216:3369-3385 pubmed publisher
  24. Gocheva V, Naba A, Bhutkar A, Guardia T, Miller K, Li C, et al. Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival. Proc Natl Acad Sci U S A. 2017;114:E5625-E5634 pubmed publisher
  25. McCauley K, Hawkins F, Serra M, Thomas D, JACOB A, Kotton D. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling. Cell Stem Cell. 2017;20:844-857.e6 pubmed publisher
  26. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  27. Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  28. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  29. Dimidschstein J, Chen Q, Tremblay R, Rogers S, Saldi G, Guo L, et al. A viral strategy for targeting and manipulating interneurons across vertebrate species. Nat Neurosci. 2016;19:1743-1749 pubmed publisher
  30. Dye B, Dedhia P, Miller A, Nagy M, White E, Shea L, et al. A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids. elife. 2016;5: pubmed publisher
  31. Dai Y, Miao Y, Wu W, Li Y, D Errico F, Su W, et al. Ablation of Liver X receptors ? and ? leads to spontaneous peripheral squamous cell lung cancer in mice. Proc Natl Acad Sci U S A. 2016;113:7614-9 pubmed publisher
  32. Loebel D, Plageman T, Tang T, Jones V, Muccioli M, Tam P. Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction. Biol Open. 2016;5:130-9 pubmed publisher
  33. Chen P, Wu T, Cheng Y, Chen C, Lee H. NKX2-1-mediated p53 expression modulates lung adenocarcinoma progression via modulating IKKβ/NF-κB activation. Oncotarget. 2015;6:14274-89 pubmed
  34. Kaisani A, Delgado O, Fasciani G, Kim S, Wright W, Minna J, et al. Branching morphogenesis of immortalized human bronchial epithelial cells in three-dimensional culture. Differentiation. 2014;87:119-26 pubmed publisher
  35. Vose L, Vinukonda G, Diamond D, Korumilli R, Hu F, Zia M, et al. Prenatal betamethasone does not affect glutamatergic or GABAergic neurogenesis in preterm newborns. Neuroscience. 2014;270:148-57 pubmed publisher
  36. McIntyre B, Alev C, Mechael R, Salci K, Lee J, Fiebig Comyn A, et al. Expansive generation of functional airway epithelium from human embryonic stem cells. Stem Cells Transl Med. 2014;3:7-17 pubmed publisher