This is a Validated Antibody Database (VAD) review about mouse Ncstn, based on 13 published articles (read how Labome selects the articles), using Ncstn antibody in all methods. It is aimed to help Labome visitors find the most suited Ncstn antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ncstn synonym: 9430068N19Rik; AA727311; Aph2; D1Dau13e; Kiaa0253; Nct; mKIAA0253

Invitrogen
domestic rabbit polyclonal
In order to investigate presenilin assembly and catalytic activity, Invitrogen Ncstn antibody (Affinity BioReagents, PA1-758) was used . J Biol Chem (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D38F9)
  • western blot; mouse; 1:1000; loading ...; fig 4i
Cell Signaling Technology Ncstn antibody (Cell Signaling, 5665) was used in western blot on mouse samples at 1:1000 (fig 4i). EMBO Rep (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3e
Cell Signaling Technology Ncstn antibody (Cell Signaling, 3632) was used in western blot on mouse samples (fig 3e). Mol Neurodegener (2020) ncbi
domestic rabbit monoclonal (D65G7)
  • western blot; mouse; 1:1000; loading ...; fig s3d
Cell Signaling Technology Ncstn antibody (Cell Signaling Technology, 9447) was used in western blot on mouse samples at 1:1000 (fig s3d). J Clin Invest (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 3d
In order to show that ALOX5 upregulation results in homocysteine-dependent worsening of the Alzheimer's disease phenotype, Cell Signaling Technology Ncstn antibody (Cell Signaling, 3632) was used in western blot on mouse samples (fig 3d). Sci Rep (2017) ncbi
domestic rabbit monoclonal (D65G7)
  • immunocytochemistry; mouse; 1:1000; loading ...; fig s3a
Cell Signaling Technology Ncstn antibody (Cell Signaling, 9447) was used in immunocytochemistry on mouse samples at 1:1000 (fig s3a). Science (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 5c
Cell Signaling Technology Ncstn antibody (Cell Signaling, 3632S) was used in western blot on human samples (fig 5c). elife (2016) ncbi
domestic rabbit monoclonal (D65G7)
  • western blot; human; fig s2
Cell Signaling Technology Ncstn antibody (Cell Signaling Tech, 9447) was used in western blot on human samples (fig s2). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D38F9)
  • western blot; mouse; fig 2
In order to characterize postmortem behavior and the rapid alteration of protein phosphorylation, Cell Signaling Technology Ncstn antibody (Cell signaling, 5665) was used in western blot on mouse samples (fig 2). Sci Rep (2015) ncbi
domestic rabbit monoclonal (D38F9)
  • western blot; mouse; fig 3c
In order to assess the efficiency and potential safety of miRNA replacement therapy for Alzheimer's disease, Cell Signaling Technology Ncstn antibody (Cell Signaling, 5665) was used in western blot on mouse samples (fig 3c). Mol Ther Nucleic Acids (2015) ncbi
domestic rabbit monoclonal (D65G7)
Cell Signaling Technology Ncstn antibody (Cell Signaling Tech, 9447) was used . Autophagy (2015) ncbi
domestic rabbit monoclonal (D65G7)
  • immunohistochemistry - frozen section; mouse; fig 5g
In order to study the effect of bisecting N-acetylglucosamine on beta-site amyloid precursor protein cleaving enzyme-1 (BACE1) activity, Cell Signaling Technology Ncstn antibody (Cell Signaling Technology, 9447S) was used in immunohistochemistry - frozen section on mouse samples (fig 5g). EMBO Mol Med (2015) ncbi
domestic rabbit monoclonal (D38F9)
  • western blot; human; loading ...; fig 6b
Cell Signaling Technology Ncstn antibody (Cell Signaling Technology Inc., 5665) was used in western blot on human samples (fig 6b). Mol Carcinog (2015) ncbi
Articles Reviewed
  1. Bera S, Camblor Perujo S, Calleja Barca E, Negrete Hurtado A, Racho J, de Bruyckere E, et al. AP-2 reduces amyloidogenesis by promoting BACE1 trafficking and degradation in neurons. EMBO Rep. 2020;21:e47954 pubmed publisher
  2. Li J, Chiu J, Ramanjulu M, Blass B, Pratico D. A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles. Mol Neurodegener. 2020;15:1 pubmed publisher
  3. Beckelman B, Yang W, Kasica N, Zimmermann H, Zhou X, Keene C, et al. Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer's disease model mice. J Clin Invest. 2019;129:820-833 pubmed publisher
  4. Li J, Barrero C, Merali S, Pratico D. Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer's phenotype. Sci Rep. 2017;7:46002 pubmed publisher
  5. Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
  6. Bolduc D, Montagna D, Seghers M, Wolfe M, Selkoe D. The amyloid-beta forming tripeptide cleavage mechanism of ?-secretase. elife. 2016;5: pubmed publisher
  7. Noh H, Hah Y, Ha J, Kang M, Zada S, Rha S, et al. Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. Oncotarget. 2016;7:4632-46 pubmed publisher
  8. Wang Y, Zhang Y, Hu W, Xie S, Gong C, Iqbal K, et al. Rapid alteration of protein phosphorylation during postmortem: implication in the study of protein phosphorylation. Sci Rep. 2015;5:15709 pubmed publisher
  9. Parsi S, Smith P, Goupil C, Dorval V, Hébert S. Preclinical Evaluation of miR-15/107 Family Members as Multifactorial Drug Targets for Alzheimer's Disease. Mol Ther Nucleic Acids. 2015;4:e256 pubmed publisher
  10. Polletta L, Vernucci E, Carnevale I, Arcangeli T, Rotili D, Palmerio S, et al. SIRT5 regulation of ammonia-induced autophagy and mitophagy. Autophagy. 2015;11:253-70 pubmed publisher
  11. Marinangeli C, Tasiaux B, Opsomer R, Hage S, Sodero A, Dewachter I, et al. Presenilin transmembrane domain 8 conserved AXXXAXXXG motifs are required for the activity of the γ-secretase complex. J Biol Chem. 2015;290:7169-84 pubmed publisher
  12. Kizuka Y, Kitazume S, Fujinawa R, Saito T, Iwata N, Saido T, et al. An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease. EMBO Mol Med. 2015;7:175-89 pubmed publisher
  13. Kaushik G, Venugopal A, Ramamoorthy P, Standing D, Subramaniam D, Umar S, et al. Honokiol inhibits melanoma stem cells by targeting notch signaling. Mol Carcinog. 2015;54:1710-21 pubmed publisher