This is a Validated Antibody Database (VAD) review about mouse Ncl, based on 39 published articles (read how Labome selects the articles), using Ncl antibody in all methods. It is aimed to help Labome visitors find the most suited Ncl antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ncl synonym: B530004O11Rik; C23; D0Nds28; D1Nds28; Nucl

Abcam
mouse monoclonal (4E2)
  • immunocytochemistry; human; 1:5000; loading ...; fig 4a
Abcam Ncl antibody (Abcam, ab13541) was used in immunocytochemistry on human samples at 1:5000 (fig 4a). Sci Rep (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 7d
Abcam Ncl antibody (Abcam, ab22758) was used in western blot on mouse samples at 1:1000 (fig 7d). J Biol Chem (2019) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 4b
Abcam Ncl antibody (Abcam, ab22758) was used in immunocytochemistry on human samples (fig 4a) and in western blot on human samples (fig 4b). J Am Chem Soc (2019) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; loading ...; fig 6a
Abcam Ncl antibody (Abcam, ab22758) was used in immunoprecipitation on human samples (fig 6a). Proc Natl Acad Sci U S A (2018) ncbi
mouse monoclonal (4E2)
  • immunohistochemistry; human; loading ...; fig 1f
Abcam Ncl antibody (Abcam, Ab13541) was used in immunohistochemistry on human samples (fig 1f). Cell (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 1f
Abcam Ncl antibody (Abcam, ab70493) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 1f). Dis Model Mech (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1c
In order to report the interactome of all dipeptide repeat proteins, Abcam Ncl antibody (Abcam, ab22758) was used in western blot on human samples (fig 1c). Cell (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; fig 1
In order to study how PARylation regulates Top1 nuclear dynamics, Abcam Ncl antibody (Abcam, ab22758) was used in immunocytochemistry on human samples (fig 1). Nucleic Acids Res (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:1000; fig 6a
  • western blot; human; 1:100; fig 7a
In order to examine the composition of mitochondrial proteins in cases of fatal familial insomnia, Abcam Ncl antibody (Abcam, Ab22758) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 6a) and in western blot on human samples at 1:100 (fig 7a). Brain Pathol (2017) ncbi
mouse monoclonal (4E2)
  • western blot; human; fig 5
Abcam Ncl antibody (AbCam, ab13541) was used in western blot on human samples (fig 5). Oncotarget (2016) ncbi
mouse monoclonal (4E2)
  • immunocytochemistry; human; 1:500; fig 9
Abcam Ncl antibody (Abcam, ab13541) was used in immunocytochemistry on human samples at 1:500 (fig 9). elife (2016) ncbi
mouse monoclonal (4E2)
  • western blot; human
Abcam Ncl antibody (Abcam, ab13541) was used in western blot on human samples . Neurobiol Aging (2015) ncbi
mouse monoclonal (4E2)
  • immunocytochemistry; human
In order to study the role of Tn expression and post-translationally modifications in pancreatic ductal adenocarcinoma, Abcam Ncl antibody (Abcam, 4E2) was used in immunocytochemistry on human samples . Mol Cancer (2015) ncbi
mouse monoclonal (4E2)
  • immunocytochemistry; human
In order to report that TopBP1 and ATR inhibit the synthesis of rRNA and activate the nucleolar stress pathway, Abcam Ncl antibody (Abcam, 4E2) was used in immunocytochemistry on human samples . Nucleic Acids Res (2015) ncbi
mouse monoclonal (4E2)
  • immunocytochemistry; human; fig 1
In order to investigate how RNA polymerase I transcription inhibition induces nucleolar disruption and autophagy, Abcam Ncl antibody (Abcam, ab-13541) was used in immunocytochemistry on human samples (fig 1). Sci Rep (2015) ncbi
mouse monoclonal (4E2)
  • immunocytochemistry; human; fig s9
Abcam Ncl antibody (abcam, ab13541) was used in immunocytochemistry on human samples (fig s9). Cell Death Differ (2015) ncbi
mouse monoclonal (4E2)
  • immunohistochemistry - paraffin section; human; 1:2000
Abcam Ncl antibody (Abcam, 4E2) was used in immunohistochemistry - paraffin section on human samples at 1:2000. J Neuroimmunol (2014) ncbi
mouse monoclonal (4E2)
  • immunocytochemistry; human; 1:500
  • immunocytochemistry; African green monkey; 1:500
In order to characterize the newly identified primate T-lymphotropic virus type 3, Abcam Ncl antibody (Abcam, ab13541) was used in immunocytochemistry on human samples at 1:500 and in immunocytochemistry on African green monkey samples at 1:500. J Virol (2015) ncbi
mouse monoclonal (4E2)
  • immunocytochemistry; human
  • western blot; human
In order to identify and characterize several p53-activating small molecules, Abcam Ncl antibody (Abcam, 4E2) was used in immunocytochemistry on human samples and in western blot on human samples . Mol Cancer Ther (2014) ncbi
mouse monoclonal (4E2)
  • western blot; human; 1:1000
Abcam Ncl antibody (Abcam, ab13541) was used in western blot on human samples at 1:1000. Biochim Biophys Acta (2014) ncbi
mouse monoclonal (4E2)
  • western blot; human
Abcam Ncl antibody (Abcam, ab13541) was used in western blot on human samples . PLoS ONE (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (MS-3)
  • immunocytochemistry; human; 1:100; loading ...; fig 2h
Santa Cruz Biotechnology Ncl antibody (SantaCruz, sc-8031) was used in immunocytochemistry on human samples at 1:100 (fig 2h). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (MS-3)
  • western blot; human; loading ...; fig 3a
Santa Cruz Biotechnology Ncl antibody (SantaCruz, sc-8031) was used in western blot on human samples (fig 3a). Open Biol (2016) ncbi
mouse monoclonal (MS-3)
  • western blot; human; loading ...; fig 1a
Santa Cruz Biotechnology Ncl antibody (Santa Cruz, SC-8031) was used in western blot on human samples (fig 1a). Oncotarget (2016) ncbi
mouse monoclonal (MS-3)
  • western blot; human; fig 4
Santa Cruz Biotechnology Ncl antibody (Santa Cruz, sc-8031) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
mouse monoclonal (MS-3)
  • western blot; human; fig 3
Santa Cruz Biotechnology Ncl antibody (Santa Cruz, sc-8031) was used in western blot on human samples (fig 3). IUBMB Life (2016) ncbi
mouse monoclonal (MS-3)
  • immunoprecipitation; human; fig S5
Santa Cruz Biotechnology Ncl antibody (Santacruz, sc-8031) was used in immunoprecipitation on human samples (fig S5). Oncotarget (2016) ncbi
mouse monoclonal (MS-3)
  • western blot; human; fig 2
Santa Cruz Biotechnology Ncl antibody (Santa Cruz, sc-8031) was used in western blot on human samples (fig 2). Oncogene (2016) ncbi
mouse monoclonal (MS-3)
  • western blot; human
Santa Cruz Biotechnology Ncl antibody (Santa Cruz, sc-8031) was used in western blot on human samples . Neurobiol Aging (2015) ncbi
mouse monoclonal (MS-3)
  • western blot; human; 1:1000
In order to study the role of Tn expression and post-translationally modifications in pancreatic ductal adenocarcinoma, Santa Cruz Biotechnology Ncl antibody (Santa Cruz, sc-8031) was used in western blot on human samples at 1:1000. Mol Cancer (2015) ncbi
mouse monoclonal (MS-3)
  • western blot; human; 1:1000; fig 3
Santa Cruz Biotechnology Ncl antibody (Santa Cruz, sc8031) was used in western blot on human samples at 1:1000 (fig 3). J Mol Biol (2015) ncbi
mouse monoclonal (MS-3)
  • immunoprecipitation; human; fig 1
  • western blot; human; fig 1
In order to characterize a potential treatment for glioblastoma by interfering with Erb1, Ras and nucleolin interactions, Santa Cruz Biotechnology Ncl antibody (Santa Cruz, sc-8031) was used in immunoprecipitation on human samples (fig 1) and in western blot on human samples (fig 1). Oncotarget (2014) ncbi
mouse monoclonal (MS-3)
  • immunocytochemistry; mouse
Santa Cruz Biotechnology Ncl antibody (Santa Cruz, sc-8031) was used in immunocytochemistry on mouse samples . Stem Cells Dev (2014) ncbi
mouse monoclonal (MS-3)
  • immunoprecipitation; human; fig s1c
Santa Cruz Biotechnology Ncl antibody (Santa, sc-8031) was used in immunoprecipitation on human samples (fig s1c). Nucleic Acids Res (2014) ncbi
Invitrogen
mouse monoclonal (ZN004)
  • western blot; human; fig 4b
In order to propose that WRN interacts with HDACs to facilitate activity of stalled replication forks under conditions of replication stress, Invitrogen Ncl antibody (Life Technologies, 396400) was used in western blot on human samples (fig 4b). J Biol Chem (2016) ncbi
mouse monoclonal (ZN004)
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 2
In order to characterize viral replication compartments isolated from adenovirus-infected cells for biochemical, morphological, and functional properties, Invitrogen Ncl antibody (Invitrogen, ZN004) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 2). J Virol (2016) ncbi
mouse monoclonal (ZN004)
  • immunocytochemistry; human; 1:100
In order to study allorecognition using Botryllus schlosseri, Invitrogen Ncl antibody (Life Technologies, 39-6400) was used in immunocytochemistry on human samples at 1:100. Immunogenetics (2015) ncbi
mouse monoclonal (ZN004)
  • immunocytochemistry; human; 1:100; fig 2
In order to examine the localization of nucleophosmin in thyroid tumors, Invitrogen Ncl antibody (Zymed Laboratories, Clone ZN004) was used in immunocytochemistry on human samples at 1:100 (fig 2). Endocr Pathol (2011) ncbi
mouse monoclonal (ZN004)
  • immunocytochemistry; human; 1:100
In order to describe a case of a therapy-responder acute myeloid leukemia patient bearing two novel NPM1 mutations, Invitrogen Ncl antibody (Zymed, ZN004) was used in immunocytochemistry on human samples at 1:100. Hematol Oncol (2010) ncbi
mouse monoclonal (ZN004)
  • immunocytochemistry; human
  • western blot; human
In order to identify APE1 partners, Invitrogen Ncl antibody (Zymed Laboratories, Invitrogen, ZN004) was used in immunocytochemistry on human samples and in western blot on human samples . Mol Cell Biol (2009) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • western blot; human; 1:4000; fig 4c
Novus Biologicals Ncl antibody (Novus, NB600-241) was used in western blot on human samples at 1:4000 (fig 4c). Sci Rep (2016) ncbi
Articles Reviewed
  1. Zaja R, Aydin G, Lippok B, Feederle R, Luscher B, Feijs K. Comparative analysis of MACROD1, MACROD2 and TARG1 expression, localisation and interactome. Sci Rep. 2020;10:8286 pubmed publisher
  2. Brody M, Vanhoutte D, Bakshi C, Liu R, Correll R, Sargent M, et al. Disruption of valosin-containing protein activity causes cardiomyopathy and reveals pleiotropic functions in cardiac homeostasis. J Biol Chem. 2019;294:8918-8929 pubmed publisher
  3. Wang F, Zhou S, Qi D, Xiang S, Wong E, Wang X, et al. Nucleolin Is a Functional Binding Protein for Salinomycin in Neuroblastoma Stem Cells. J Am Chem Soc. 2019;141:3613-3622 pubmed publisher
  4. Castanotto D, Zhang X, Alluin J, Zhang X, Rüger J, Armstrong B, et al. A stress-induced response complex (SIRC) shuttles miRNAs, siRNAs, and oligonucleotides to the nucleus. Proc Natl Acad Sci U S A. 2018;115:E5756-E5765 pubmed publisher
  5. Xing Y, Yao R, Zhang Y, Guo C, Jiang S, Xu G, et al. SLERT Regulates DDX21 Rings Associated with Pol I Transcription. Cell. 2017;169:664-678.e16 pubmed publisher
  6. Evsyukov V, Domanskyi A, Bierhoff H, Gispert S, Mustafa R, Schlaudraff F, et al. Genetic mutations linked to Parkinson's disease differentially control nucleolar activity in pre-symptomatic mouse models. Dis Model Mech. 2017;10:633-643 pubmed publisher
  7. Coccia M, Rossi A, Riccio A, Trotta E, Santoro M. Human NF-κB repressing factor acts as a stress-regulated switch for ribosomal RNA processing and nucleolar homeostasis surveillance. Proc Natl Acad Sci U S A. 2017;114:1045-1050 pubmed publisher
  8. Samson A, Ho B, Au A, Schoenwaelder S, Smyth M, Bottomley S, et al. Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells. Open Biol. 2016;6: pubmed
  9. Lee K, Zhang P, Kim H, Mitrea D, Sarkar M, Freibaum B, et al. C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Cell. 2016;167:774-788.e17 pubmed publisher
  10. Kehrli K, Phelps M, Lazarchuk P, Chen E, Monnat R, Sidorova J. Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest. J Biol Chem. 2016;291:24487-24503 pubmed
  11. Das S, Rehman I, Ghosh A, Sengupta S, Majumdar P, Jana B, et al. Poly(ADP-ribose) polymers regulate DNA topoisomerase I (Top1) nuclear dynamics and camptothecin sensitivity in living cells. Nucleic Acids Res. 2016;44:8363-75 pubmed publisher
  12. Robijns J, Molenberghs F, Sieprath T, Corne T, Verschuuren M, De Vos W. In silico synchronization reveals regulators of nuclear ruptures in lamin A/C deficient model cells. Sci Rep. 2016;6:30325 pubmed publisher
  13. Kim Y, Lee M, Kim H, Kim J. Ribosomal protein S3 (rpS3) secreted from various cancer cells is N-linked glycosylated. Oncotarget. 2016;7:80350-80362 pubmed publisher
  14. Terrier O, Carron C, de Chassey B, Dubois J, Traversier A, Julien T, et al. Nucleolin interacts with influenza A nucleoprotein and contributes to viral ribonucleoprotein complexes nuclear trafficking and efficient influenza viral replication. Sci Rep. 2016;6:29006 pubmed publisher
  15. Frau Méndez M, Fernández Vega I, Ansoleaga B, Blanco Tech R, Carmona Tech M, Antonio Del Río J, et al. Fatal familial insomnia: mitochondrial and protein synthesis machinery decline in the mediodorsal thalamus. Brain Pathol. 2017;27:95-106 pubmed publisher
  16. Mori F, Ferraiuolo M, Santoro R, Sacconi A, Goeman F, Pallocca M, et al. Multitargeting activity of miR-24 inhibits long-term melatonin anticancer effects. Oncotarget. 2016;7:20532-48 pubmed publisher
  17. Sobecki M, Mrouj K, Camasses A, Parisis N, Nicolas E, Llères D, et al. The cell proliferation antigen Ki-67 organises heterochromatin. elife. 2016;5:e13722 pubmed publisher
  18. Bober J, Olsnes S, Kostas M, Bogacz M, Zakrzewska M, Otlewski J. Identification of new FGF1 binding partners-Implications for its intracellular function. IUBMB Life. 2016;68:242-51 pubmed publisher
  19. Hidalgo P, Anzures L, Hernández Mendoza A, Guerrero A, Wood C, Valdés M, et al. Morphological, Biochemical, and Functional Study of Viral Replication Compartments Isolated from Adenovirus-Infected Cells. J Virol. 2016;90:3411-27 pubmed publisher
  20. Nogales V, Reinhold W, Varma S, Martinez Cardus A, Moutinho C, Moran S, et al. Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs. Oncotarget. 2016;7:3084-97 pubmed publisher
  21. Felli N, Errico M, Pedini F, Petrini M, Puglisi R, Bellenghi M, et al. AP2α controls the dynamic balance between miR-126&126* and miR-221&222 during melanoma progression. Oncogene. 2016;35:3016-26 pubmed publisher
  22. Taketa D, Nydam M, Langenbacher A, Rodriguez D, Sanders E, De Tomaso A. Molecular evolution and in vitro characterization of Botryllus histocompatibility factor. Immunogenetics. 2015;67:605-23 pubmed publisher
  23. Li M, Pehar M, Liu Y, Bhattacharyya A, Zhang S, O Riordan K, et al. The amyloid precursor protein (APP) intracellular domain regulates translation of p44, a short isoform of p53, through an IRES-dependent mechanism. Neurobiol Aging. 2015;36:2725-36 pubmed publisher
  24. Hofmann B, Schlüter L, Lange P, Mercanoglu B, Ewald F, Fölster A, et al. COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer. Mol Cancer. 2015;14:109 pubmed publisher
  25. Sokka M, Rilla K, Miinalainen I, Pospiech H, Syväoja J. High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar segregation. Nucleic Acids Res. 2015;43:4975-89 pubmed publisher
  26. Katagiri N, Kuroda T, Kishimoto H, Hayashi Y, Kumazawa T, Kimura K. The nucleolar protein nucleophosmin is essential for autophagy induced by inhibiting Pol I transcription. Sci Rep. 2015;5:8903 pubmed publisher
  27. Warren D, Tajsic T, Porter L, Minaisah R, Cobb A, Jacob A, et al. Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing. Cell Death Differ. 2015;22:1540-50 pubmed publisher
  28. Szerlong H, Herman J, Krause C, DeLuca J, Skoultchi A, Winger Q, et al. Proteomic characterization of the nucleolar linker histone H1 interaction network. J Mol Biol. 2015;427:2056-71 pubmed publisher
  29. Kong L, Wei J, Haider A, Liebelt B, Ling X, Conrad C, et al. Therapeutic targets in subependymoma. J Neuroimmunol. 2014;277:168-75 pubmed publisher
  30. Turpin J, Journo C, Ko N, Sinet F, Carpentier A, Galioot A, et al. Discovery and characterization of auxiliary proteins encoded by type 3 simian T-cell lymphotropic viruses. J Virol. 2015;89:931-51 pubmed publisher
  31. Peltonen K, Colis L, Liu H, Jäämaa S, Zhang Z, Af Hällström T, et al. Small molecule BMH-compounds that inhibit RNA polymerase I and cause nucleolar stress. Mol Cancer Ther. 2014;13:2537-46 pubmed publisher
  32. Goldshmit Y, Trangle S, Kloog Y, Pinkas Kramarski R. Interfering with the interaction between ErbB1, nucleolin and Ras as a potential treatment for glioblastoma. Oncotarget. 2014;5:8602-13 pubmed
  33. Su L, Zheng H, Li Z, Qiu J, Chen S, Liu J, et al. Mechanistic studies on the anticancer activity of 2,4-disubstituted quinazoline derivative. Biochim Biophys Acta. 2014;1840:3123-30 pubmed publisher
  34. Lührig S, Siamishi I, Tesmer Wolf M, Zechner U, Engel W, Nolte J. Lrrc34, a novel nucleolar protein, interacts with npm1 and ncl and has an impact on pluripotent stem cells. Stem Cells Dev. 2014;23:2862-74 pubmed publisher
  35. Ullius A, Lüscher Firzlaff J, Costa I, Walsemann G, Forst A, Gusmao E, et al. The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification. Nucleic Acids Res. 2014;42:6901-20 pubmed publisher
  36. Wakai M, Abe S, Kazuki Y, Oshimura M, Ishikawa F. A human artificial chromosome recapitulates the metabolism of native telomeres in mammalian cells. PLoS ONE. 2014;9:e88530 pubmed publisher
  37. Pianta A, Puppin C, Passon N, Franzoni A, Romanello M, Tell G, et al. Nucleophosmin delocalization in thyroid tumour cells. Endocr Pathol. 2011;22:18-23 pubmed publisher
  38. Pianta A, Fabbro D, Damiani D, Tiribelli M, Fanin R, Franzoni A, et al. Two novel NPM1 mutations in a therapy-responder AML patient. Hematol Oncol. 2010;28:151-5 pubmed publisher
  39. Vascotto C, Fantini D, Romanello M, Cesaratto L, Deganuto M, Leonardi A, et al. APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process. Mol Cell Biol. 2009;29:1834-54 pubmed publisher