This is a Validated Antibody Database (VAD) review about mouse NFATc2, based on 29 published articles (read how Labome selects the articles), using NFATc2 antibody in all methods. It is aimed to help Labome visitors find the most suited NFATc2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NFATc2 synonym: AI607462; NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp

Santa Cruz Biotechnology
mouse monoclonal (4G6-G5)
  • immunohistochemistry - frozen section; mouse; loading ...; fig s3
  • western blot; mouse; loading ...; fig s2
Santa Cruz Biotechnology NFATc2 antibody (Santa Cruz, sc-7296) was used in immunohistochemistry - frozen section on mouse samples (fig s3) and in western blot on mouse samples (fig s2). iScience (2022) ncbi
mouse monoclonal (4G6-G5)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 6d
Santa Cruz Biotechnology NFATc2 antibody (Santa Cruz Biotech, sc-7296) was used in immunohistochemistry on mouse samples at 1:100 (fig 6d). PLoS Biol (2021) ncbi
mouse monoclonal (4G6-G5)
  • western blot; rat; 1:500; loading ...; fig 4c
Santa Cruz Biotechnology NFATc2 antibody (Santa Cruz Biotechnology, 4G6-G5) was used in western blot on rat samples at 1:500 (fig 4c). Sci Rep (2017) ncbi
mouse monoclonal (4G6-G5)
  • western blot; human; loading ...; fig 3a
In order to show that NFATC3 promotes IRF7-mediated IFN production, Santa Cruz Biotechnology NFATc2 antibody (Santa Cruz, sc-7296) was used in western blot on human samples (fig 3a). J Exp Med (2016) ncbi
mouse monoclonal (4G6-G5)
  • western blot; human; fig 2
Santa Cruz Biotechnology NFATc2 antibody (Santa Cruz, 4G6-G5) was used in western blot on human samples (fig 2). Oncotarget (2016) ncbi
mouse monoclonal (4G6-G5)
  • western blot; mouse; fig 6c
Santa Cruz Biotechnology NFATc2 antibody (Santa Cruz Biotechnology, 4G6-G5) was used in western blot on mouse samples (fig 6c). J Exp Med (2015) ncbi
mouse monoclonal (4G6-G5)
  • chromatin immunoprecipitation; human; fig 5h
Santa Cruz Biotechnology NFATc2 antibody (Santa Cruz, sc-7296) was used in chromatin immunoprecipitation on human samples (fig 5h). Nat Commun (2015) ncbi
mouse monoclonal (4G6-G5)
  • western blot; mouse
In order to determine that SOCE regulates UDP-induced phagocytosis and LPS-stimulated cytokine secretion in microglia, Santa Cruz Biotechnology NFATc2 antibody (Santa Cruz, sc-7296) was used in western blot on mouse samples . Cell Signal (2015) ncbi
mouse monoclonal (4G6-G5)
  • western blot; human; loading ...; fig 4e
Santa Cruz Biotechnology NFATc2 antibody (SantaCruz, sc-7296) was used in western blot on human samples (fig 4e). Cell Death Dis (2014) ncbi
Abcam
mouse monoclonal (25A10.D6.D2)
  • immunohistochemistry - frozen section; rat; fig 2
  • western blot; rat; 1:100
Abcam NFATc2 antibody (Abcam, ab2722) was used in immunohistochemistry - frozen section on rat samples (fig 2) and in western blot on rat samples at 1:100. J Neurosci (2016) ncbi
mouse monoclonal (25A10.D6.D2)
  • immunocytochemistry; human; fig s6a
In order to identify analogs of harmine as a new class of human beta cell mitogenic compounds and identify the pathways they activate, Abcam NFATc2 antibody (Abcam, ab2722) was used in immunocytochemistry on human samples (fig s6a). Nat Med (2015) ncbi
mouse monoclonal (25A10.D6.D2)
  • western blot; human; fig 6
Abcam NFATc2 antibody (Abcam, ab2722) was used in western blot on human samples (fig 6). PLoS ONE (2015) ncbi
mouse monoclonal (25A10.D6.D2)
  • western blot; human; fig 2
Abcam NFATc2 antibody (Abcam, ab2722) was used in western blot on human samples (fig 2). Mol Cell Biol (2015) ncbi
mouse monoclonal (25A10.D6.D2)
  • chromatin immunoprecipitation; human
In order to study the eigenetic role of PARP-1 as a memory marker in mitotic chromatin, Abcam NFATc2 antibody (Abcam, ab2722) was used in chromatin immunoprecipitation on human samples . Nucleic Acids Res (2014) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3a
Invitrogen NFATc2 antibody (Thermo Fisher, 44-944G) was used in western blot on human samples at 1:1000 (fig 3a). World J Surg Oncol (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 7a
Invitrogen NFATc2 antibody (Thermo Fisher, PA5-64484) was used in western blot on human samples (fig 7a). Sci Rep (2021) ncbi
mouse monoclonal (25A10.D6.D2)
  • western blot; human; 1:1000; loading ...; fig 5a
In order to identify factors that contribute to the progression of fibrosis in lung allografts, Invitrogen NFATc2 antibody (Thermo Fisher Scientific, MA1-025) was used in western blot on human samples at 1:1000 (fig 5a). J Clin Invest (2017) ncbi
mouse monoclonal (25A10.D6.D2)
  • immunocytochemistry; mouse; 1:500; fig 5A
In order to evaluate the potential role of the attachment of myristic acid to the N-terminal glycine of proteins on the activation of gamma delta T cells, Invitrogen NFATc2 antibody (Thermo Fisher, MA1-025) was used in immunocytochemistry on mouse samples at 1:500 (fig 5A). J Leukoc Biol (2017) ncbi
domestic rabbit polyclonal
In order to determine that SOCE regulates UDP-induced phagocytosis and LPS-stimulated cytokine secretion in microglia, Invitrogen NFATc2 antibody (Invitrogen, 44944G) was used . Cell Signal (2015) ncbi
Novus Biologicals
mouse monoclonal (25A10.D6.D2)
  • immunocytochemistry; rat; 1:100; fig 3f
Novus Biologicals NFATc2 antibody (Novus Biologicals, NB300-504) was used in immunocytochemistry on rat samples at 1:100 (fig 3f). Exp Ther Med (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D43B1)
  • immunocytochemistry; human; 1:100; loading ...; fig 5e
  • western blot; human; loading ...; fig 6b
Cell Signaling Technology NFATc2 antibody (CST, 5861) was used in immunocytochemistry on human samples at 1:100 (fig 5e) and in western blot on human samples (fig 6b). Theranostics (2021) ncbi
domestic rabbit monoclonal (D43B1)
  • ChIP-Seq; human; loading ...; fig 3b
  • western blot; human; loading ...; fig s5a
Cell Signaling Technology NFATc2 antibody (Cell Signaling, 5861) was used in ChIP-Seq on human samples (fig 3b) and in western blot on human samples (fig s5a). J Exp Med (2020) ncbi
domestic rabbit monoclonal (D43B1)
  • western blot; mouse; 1:1000; loading ...; fig 4a
Cell Signaling Technology NFATc2 antibody (CST, D43B1) was used in western blot on mouse samples at 1:1000 (fig 4a). Transl Psychiatry (2019) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:500; loading ...; fig 1d
Cell Signaling Technology NFATc2 antibody (Cell Signaling, 4389S) was used in immunocytochemistry on mouse samples at 1:500 (fig 1d). Nat Commun (2018) ncbi
domestic rabbit polyclonal
  • flow cytometry; human; loading ...
In order to evaluate the parallel microfluidic cytometer for the analysis of human primary T cells, Cell Signaling Technology NFATc2 antibody (CST, 4389) was used in flow cytometry on human samples . SLAS Discov (2017) ncbi
domestic rabbit monoclonal (D43B1)
  • immunocytochemistry; mouse; 1:100; fig 5e
Cell Signaling Technology NFATc2 antibody (Cell signaling, D43B1) was used in immunocytochemistry on mouse samples at 1:100 (fig 5e). J Exp Med (2017) ncbi
domestic rabbit monoclonal (D43B1)
  • western blot; mouse; loading ...
In order to discuss the role of NFAT in type II diabetes, Cell Signaling Technology NFATc2 antibody (Cell Signaling, 5861S) was used in western blot on mouse samples . PLoS Genet (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; fig 4
  • western blot; mouse; fig 4
Cell Signaling Technology NFATc2 antibody (Cell Signaling, 4389S) was used in immunocytochemistry on mouse samples (fig 4) and in western blot on mouse samples (fig 4). Nature (2016) ncbi
domestic rabbit monoclonal (D43B1)
  • western blot; mouse; fig 5
In order to determine the response threshold of immunoreceptor tyrosine-based activation motifs, Cell Signaling Technology NFATc2 antibody (Cell Signaling, 5861) was used in western blot on mouse samples (fig 5). elife (2015) ncbi
domestic rabbit monoclonal (D43B1)
  • western blot; human; 1:500; fig 5a &i
Cell Signaling Technology NFATc2 antibody (Cell Signaling Technologies, 5861) was used in western blot on human samples at 1:500 (fig 5a &i). Nat Commun (2015) ncbi
domestic rabbit monoclonal (D43B1)
  • immunocytochemistry; mouse; 1:20; fig 5d
  • western blot; mouse; 1:1000; fig 5c
In order to explore a macrophage TLR9-BTK-calcineurin-NFAT signaling pathway involved in impair fungal immunity, Cell Signaling Technology NFATc2 antibody (Cell signaling, 5861) was used in immunocytochemistry on mouse samples at 1:20 (fig 5d) and in western blot on mouse samples at 1:1000 (fig 5c). EMBO Mol Med (2015) ncbi
Articles Reviewed
  1. Du M, Wang C, Yang L, Liu B, Zheng Z, Yang L, et al. The role of long noncoding RNA Nron in atherosclerosis development and plaque stability. iScience. 2022;25:103978 pubmed publisher
  2. Li W, Zheng J, Zhao G, Lyu C, Lu W. Overexpression of DSCR1 prevents proliferation and predicts favorable prognosis in colorectal cancer patients. World J Surg Oncol. 2021;19:100 pubmed publisher
  3. Wang J, Zhao H, Zheng L, Zhou Y, Wu L, Xu Y, et al. FGF19/SOCE/NFATc2 signaling circuit facilitates the self-renewal of liver cancer stem cells. Theranostics. 2021;11:5045-5060 pubmed publisher
  4. Sripada A, Sirohi K, Michalec L, Guo L, McKay J, Yadav S, et al. Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases. PLoS Biol. 2021;19:e3001063 pubmed publisher
  5. Zhang P, Ishikawa M, Doyle A, Nakamura T, He B, Yamada Y. Pannexin 3 regulates skin development via Epiprofin. Sci Rep. 2021;11:1779 pubmed publisher
  6. Yukawa M, Jagannathan S, Vallabh S, Kartashov A, Chen X, Weirauch M, et al. AP-1 activity induced by co-stimulation is required for chromatin opening during T cell activation. J Exp Med. 2020;217: pubmed publisher
  7. Amal H, Gong G, Gjoneska E, Lewis S, Wishnok J, Tsai L, et al. S-nitrosylation of E3 ubiquitin-protein ligase RNF213 alters non-canonical Wnt/Ca+2 signaling in the P301S mouse model of tauopathy. Transl Psychiatry. 2019;9:44 pubmed publisher
  8. Mencarelli A, Khameneh H, Fric J, Vacca M, El Daker S, Janela B, et al. Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis. Nat Commun. 2018;9:1102 pubmed publisher
  9. Wang S, Ehrlich D. Image-Based Phenotypic Screening with Human Primary T Cells Using One-Dimensional Imaging Cytometry with Self-Tuning Statistical-Gating Algorithms. SLAS Discov. 2017;22:985-994 pubmed publisher
  10. Honjoh C, Chihara K, Yoshiki H, Yamauchi S, Takeuchi K, Kato Y, et al. Association of C-Type Lectin Mincle with FcεRIβγ Subunits Leads to Functional Activation of RBL-2H3 Cells through Syk. Sci Rep. 2017;7:46064 pubmed publisher
  11. Cao P, Aoki Y, Badri L, Walker N, Manning C, Lagstein A, et al. Autocrine lysophosphatidic acid signaling activates ?-catenin and promotes lung allograft fibrosis. J Clin Invest. 2017;127:1517-1530 pubmed publisher
  12. Rampoldi F, Brunk F, Bonrouhi M, Federico G, Krunic D, Porubsky S, et al. Deficiency of N-myristoylation reveals calcineurin activity as regulator of IFN-?-producing ?? T cells. J Leukoc Biol. 2017;101:1005-1014 pubmed publisher
  13. von Moltke J, O Leary C, Barrett N, Kanaoka Y, Austen K, Locksley R. Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. J Exp Med. 2017;214:27-37 pubmed publisher
  14. Keller M, Paul P, Rabaglia M, Stapleton D, Schueler K, Broman A, et al. The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets. PLoS Genet. 2016;12:e1006466 pubmed publisher
  15. Bao M, Wang Y, Liu Y, Shi P, Lu H, Sha W, et al. NFATC3 promotes IRF7 transcriptional activity in plasmacy--toid dendritic cells. J Exp Med. 2016;213:2383-2398 pubmed
  16. Eriksson J, Le Joncour V, Nummela P, Jahkola T, Virolainen S, Laakkonen P, et al. Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression. Oncotarget. 2016;7:15065-92 pubmed publisher
  17. Liu J, Han Z, Han Z, He Z. Mesenchymal stem cell-conditioned media suppresses inflammation-associated overproliferation of pulmonary artery smooth muscle cells in a rat model of pulmonary hypertension. Exp Ther Med. 2016;11:467-475 pubmed
  18. Furman J, Sompol P, Kraner S, Pleiss M, Putman E, Dunkerson J, et al. Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury. J Neurosci. 2016;36:1502-15 pubmed publisher
  19. Luchsinger L, de Almeida M, Corrigan D, Mumau M, Snoeck H. Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential. Nature. 2016;529:528-31 pubmed publisher
  20. Freedman T, Tan Y, Skrzypczynska K, Manz B, Sjaastad F, Goodridge H, et al. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. elife. 2015;4: pubmed publisher
  21. Zou Q, Jin J, Xiao Y, Hu H, Zhou X, Jie Z, et al. T cell development involves TRAF3IP3-mediated ERK signaling in the Golgi. J Exp Med. 2015;212:1323-36 pubmed publisher
  22. SCANLON C, Banerjee R, Inglehart R, Liu M, Russo N, Hariharan A, et al. Galanin modulates the neural niche to favour perineural invasion in head and neck cancer. Nat Commun. 2015;6:6885 pubmed publisher
  23. Wang P, Alvarez Perez J, Felsenfeld D, Liu H, Sivendran S, Bender A, et al. A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication. Nat Med. 2015;21:383-8 pubmed publisher
  24. Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed publisher
  25. Yost E, Hynes T, Hartle C, Ott B, Berlot C. Inhibition of G-protein βγ signaling enhances T cell receptor-stimulated interleukin 2 transcription in CD4+ T helper cells. PLoS ONE. 2015;10:e0116575 pubmed publisher
  26. Heo D, Lim H, Nam J, Lee M, Kim J. Regulation of phagocytosis and cytokine secretion by store-operated calcium entry in primary isolated murine microglia. Cell Signal. 2015;27:177-86 pubmed publisher
  27. Makowski S, Wang Z, Pomerantz J. A protease-independent function for SPPL3 in NFAT activation. Mol Cell Biol. 2015;35:451-67 pubmed publisher
  28. Geismann C, Grohmann F, Sebens S, Wirths G, Dreher A, Häsler R, et al. c-Rel is a critical mediator of NF-κB-dependent TRAIL resistance of pancreatic cancer cells. Cell Death Dis. 2014;5:e1455 pubmed publisher
  29. Lodhi N, Kossenkov A, Tulin A. Bookmarking promoters in mitotic chromatin: poly(ADP-ribose)polymerase-1 as an epigenetic mark. Nucleic Acids Res. 2014;42:7028-38 pubmed publisher