This is a Validated Antibody Database (VAD) review about mouse Msh2, based on 42 published articles (read how Labome selects the articles), using Msh2 antibody in all methods. It is aimed to help Labome visitors find the most suited Msh2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Msh2 synonym: AI788990
Knockout validation
| Invitrogen mouse monoclonal (FE11) |
| Invitrogen Msh2 antibody (Invitrogen, FE11) was used in western blot knockout validation on mouse samples (fig s2a). Science (2019) ncbi |
| Abcam domestic rabbit polyclonal |
| Abcam Msh2 antibody (Abcam, ab70270) was used in western blot knockout validation on mouse samples at 1:10,000 (fig 4). PLoS Genet (2016) ncbi |
Invitrogen
| mouse monoclonal (FE11) |
| Invitrogen Msh2 antibody (Thermo Fisher, 33-7900) was used in western blot on human samples (fig 1s1c). elife (2019) ncbi |
| mouse monoclonal (FE11) |
| Invitrogen Msh2 antibody (Invitrogen, FE11) was used in western blot knockout validation on mouse samples (fig s2a). Science (2019) ncbi |
| mouse monoclonal (FE11) |
| In order to determine the prognostic impact of parameters in peritoneal carcinomatosis from colorectal cancer, Invitrogen Msh2 antibody (Invitrogen, FE11) was used in immunohistochemistry - paraffin section on human samples (tbl 2). Am J Surg (2017) ncbi |
| mouse monoclonal (FE11) |
| In order to utilize ovarian cancer xenograft models to study dynamic modulation of phosphoprotein expression, Invitrogen Msh2 antibody (Invitrogen, 33-7900) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig s1). BMC Cancer (2016) ncbi |
| mouse monoclonal (FE11) |
| In order to assess how proportional balance of tumor associated macrophages and tumor infiltrating lymphocytes in microsatellite-unstable gastric carcinoma is a prognostic indicator of M2 macrophages, Invitrogen Msh2 antibody (Invitrogen, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:200. PLoS ONE (2015) ncbi |
| mouse monoclonal (FE11) |
| In order to elucidate the clinicopathologic characteristics of hereditary nonpolyposis colorectal cancer patients who had both endometrial and colorectal cancers, Invitrogen Msh2 antibody (Life Technologies, FE11) was used in immunohistochemistry - paraffin section on human samples . Obstet Gynecol Sci (2015) ncbi |
| mouse monoclonal (FE11) |
| In order to assess the detection of the BRAF mutation by immunohistochemistry on tissue microarray, Invitrogen Msh2 antibody (Invitrogen, FE11) was used in immunohistochemistry on human samples at 1:100. Appl Immunohistochem Mol Morphol (2016) ncbi |
| mouse monoclonal (FE11) |
| In order to determine the association of microsatellite instability with mismatch repair proteins in epithelial cancer samples, Invitrogen Msh2 antibody (Zymed/Invitrogen, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:200. Genet Test Mol Biomarkers (2014) ncbi |
| mouse monoclonal (FE11) |
| In order to identify and characterize BRAF mutation from patients with metanephric adenomas, Invitrogen Msh2 antibody (Invitrogen, FE11) was used in immunohistochemistry on human samples at 1:100 (fig 1). Cancer Genet (2013) ncbi |
| mouse monoclonal (FE11) |
| In order to report the first case of filiform polyposis associated with adenomas developed on filiform polyps and invasive colonic adenocarcinoma in a patient without history of inflammatory bowel disease, Invitrogen Msh2 antibody (Invitrogen, FE11) was used in immunohistochemistry - paraffin section on human samples (fig 2). Pathol Res Pract (2014) ncbi |
| mouse monoclonal (FE11) |
| In order to study the elevated hMLH1 expression observed in EGFR-mutated non-small cell lung cancer, Invitrogen Msh2 antibody (Invitrogen, clone FE11) was used in immunohistochemistry on human samples at 1:250 (tbl 1). PLoS ONE (2013) ncbi |
| mouse monoclonal (FE11) |
| In order to assess the effects of fermentation products produced by the human gut flora on human adenocarcinoma colon cancer cells, Invitrogen Msh2 antibody (Invitrogen, 33-7900) was used in western blot on human samples (fig 7). J Agric Food Chem (2012) ncbi |
| mouse monoclonal (FE11) |
| In order to examine mismatch repair protein expression in epithelial ovarian cancer samples, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:200 (tbl 2). Anticancer Res (2012) ncbi |
| mouse monoclonal (FE11) |
| In order to elucidate the pathogenesis of diffuse large B-cell lymphoma, Invitrogen Msh2 antibody (ZYMED, FE11) was used in immunohistochemistry - paraffin section on human samples (fig 3). Leuk Lymphoma (2013) ncbi |
| mouse monoclonal (FE11) |
| In order to determine the roles of p53 and hMSH2 proteins in oral squamous cell carcinoma and oral dysplastic lesions, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples (fig 3). Oral Oncol (2012) ncbi |
| mouse monoclonal (FE11) |
| In order to examine patients with renal medullary carcinoma with and without sickle cell anemia, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples . Hum Pathol (2011) ncbi |
| mouse monoclonal (FE11) |
| In order to elucidate how synthetic sickness/lethality affects cancer cells, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 4). Cancer Cell (2010) ncbi |
| mouse monoclonal (FE11) |
| In order to measure the frequency of mismatch repair deficiencies in women diagnosed with endometrial cancer who are at-risk for Lynch syndrome, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples . Fam Cancer (2010) ncbi |
| mouse monoclonal (FE11) |
| In order to discuss biomarkers for insulinomas, Invitrogen Msh2 antibody (Zymed Laboratories, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:100. J Clin Endocrinol Metab (2009) ncbi |
| mouse monoclonal (FE11) |
| In order to assess the relationship between clinicopathological features and expression of hMLH1 and hMSH2 proteins in pleomorphic adenoma of minor salivary glands, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 2). Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) ncbi |
| mouse monoclonal (FE11) |
| In order to correlate microstellite instability and other clinicopathologic markers with survival of patients with high grade endometrial carcinoma, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:150. Gynecol Oncol (2009) ncbi |
| mouse monoclonal (FE11) |
| In order to discuss the use of microarrays to study ovarian cancer, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:200. Cancer Epidemiol Biomarkers Prev (2009) ncbi |
| mouse monoclonal (FE11) |
| In order to determine the expression of Bcl-2, hMLH1, and hMSH2 in patients with advanced colorectal cancer and correlate their expression with therapeutic response and disease outcome, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples (fig 1). Oncol Rep (2008) ncbi |
| mouse monoclonal (FE11) |
| In order to detect expression of MMR gene products hMSH2 and hMSH6 in urothelial carcinoma of the bladder, Invitrogen Msh2 antibody (Zymed Laboratories, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:140. APMIS (2008) ncbi |
| mouse monoclonal (FE11) |
| In order to quantify expression levels of mismatch repair proteins hMSH2, hMLH1, PCNA and Ki67 in the mucosae collected from the patients with gastric cancer, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:250 (fig 1). Oncol Rep (2008) ncbi |
| mouse monoclonal (FE11) |
| In order to identify the number of hereditary nonpolyposis colorectal cancer patients that exist among endometrial cancer patients, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples . Int J Cancer (2008) ncbi |
| mouse monoclonal (FE11) |
| In order to evaluate thymidylate synthase and microsatellite instability in colorectal cancer, Invitrogen Msh2 antibody (Zymed Laboratories, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:100. Acta Oncol (2008) ncbi |
| mouse monoclonal (FE11) |
| In order to provide evidence that carcinosarcomas are clonal malignancies, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 1). Mod Pathol (2006) ncbi |
| mouse monoclonal (FE11) |
| In order to assess patients with pure squamous cell carcinoma of the uterine cervix for loss of heterozygosity and microsatellite instability, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples . Int J Gynecol Cancer (2006) ncbi |
| mouse monoclonal (FE11) |
| In order to discuss the numbers of colorectal cancer cases based on Amsterdam I and II criteria, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry on human samples at 1:100. Fam Cancer (2005) ncbi |
| mouse monoclonal (FE11) |
| In order to compare alpha-methylacyl coenzyme A racemase expression in primary small intestinal adenocarcinomas and colorectal adenocarcinomas, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples . Am J Surg Pathol (2005) ncbi |
| mouse monoclonal (FE11) |
| In order to study the role of high thymidylate synthase expression in colorectal cancer with microsatellite instability, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples . Clin Cancer Res (2005) ncbi |
| mouse monoclonal (FE11) |
| In order to determine the function of BRAF in ulcerative colitis-related colorectal carcinogenesis, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry on human samples at 1:20. Int J Cancer (2005) ncbi |
| mouse monoclonal (FE11) |
| In order to identify the molecular profiles of patients with rectal cancers treated with neoadjuvant chemotherapy, radiotherapy, and surgery that correlate therapeutic responses, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:400. Anticancer Res (2004) ncbi |
| mouse monoclonal (FE11) |
| In order to elucidate how crypt stem cells contribute to the development of colon cancer, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:400. Am J Pathol (2004) ncbi |
| mouse monoclonal (FE11) |
| In order to assess the number and types of malignancies in patients with endometrial carcinoma with and without microsatellite instability, Invitrogen Msh2 antibody (Zymed, FE11) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 4). Clin Cancer Res (2004) ncbi |
Abcam
| domestic rabbit polyclonal |
| Abcam Msh2 antibody (Abcam, ab70270) was used in western blot knockout validation on mouse samples at 1:10,000 (fig 4). PLoS Genet (2016) ncbi |
Cell Signaling Technology
| domestic rabbit monoclonal (D24B5) |
| Cell Signaling Technology Msh2 antibody (Cell Signaling, 2017) was used in western blot on human samples at 1:1000 (fig 4b) and in western blot on mouse samples at 1:1000 (fig 3d). Adv Sci (Weinh) (2022) ncbi |
| domestic rabbit monoclonal (D24B5) |
| Cell Signaling Technology Msh2 antibody (Cell Signaling Technology, 2017) was used in immunohistochemistry on mouse samples at 1:500. JCI Insight (2020) ncbi |
| domestic rabbit monoclonal (D24B5) |
| Cell Signaling Technology Msh2 antibody (Signaling Technology, 2017) was used in western blot on human samples (fig s3). J Cell Mol Med (2016) ncbi |
| domestic rabbit monoclonal (D24B5) |
| In order to elucidate the function of TRIM29 in double stranded break repair, Cell Signaling Technology Msh2 antibody (Cell signalling, 2,017) was used in western blot on human samples at 1:1000 (fig 1g). Nat Commun (2015) ncbi |
| domestic rabbit monoclonal (D24B5) |
| In order to evaluate the effect of NVP-BEZ235 and MEK inhibitor ADZ4266 on murine mismatch repair deficient tumors, Cell Signaling Technology Msh2 antibody (Cell Signaling Technologies, 2017S) was used in immunohistochemistry - paraffin section on human samples at 1:200 and in western blot on human samples . PLoS ONE (2013) ncbi |
Articles Reviewed
- Boulagnon C, Dudez O, Beaudoux O, Dalstein V, Kianmanesh R, Bouché O, et al. BRAFV600E Gene Mutation in Colonic Adenocarcinomas. Immunohistochemical Detection Using Tissue Microarray and Clinicopathologic Characteristics: An 86 Case Series. Appl Immunohistochem Mol Morphol. 2016;24:88-96 pubmed publisher
- Dadone B, Ambrosetti D, Carpentier X, Duranton Tanneur V, Burel Vandenbos F, Amiel J, et al. A renal metanephric adenoma showing both a 2p16e24 deletion and BRAF V600E mutation: a synergistic role for a tumor suppressor gene on chromosome 2p and BRAF activation?. Cancer Genet. 2013;206:347-52 pubmed
- Campos Vega R, García Gasca T, Guevara González R, Ramos Gomez M, Oomah B, Loarca Pina G. Human gut flora-fermented nondigestible fraction from cooked bean ( Phaseolus vulgaris L.) modifies protein expression associated with apoptosis, cell cycle arrest, and proliferation in human adenocarcinoma colon cancer cells. J Agric Food Chem. 2012;60:12443-50 pubmed publisher
- Coppola D, Nicosia S, Doty A, Sellers T, Lee J, Fulp J, et al. Uncertainty in the utility of immunohistochemistry in mismatch repair protein expression in epithelial ovarian cancer. Anticancer Res. 2012;32:4963-9 pubmed
- Tobón Arroyave S, Flórez Moreno G, Jaramillo Cárdenas J, Arango Uribe J, Isaza Guzmán D, Rendón Henao J. Expression of hMLH1 and hMSH2 proteins in pleomorphic adenoma of minor salivary glands: relationship with clinical and histologic findings. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108:227-36 pubmed publisher
- Bendardaf R, Lamlum H, Ristamaki R, Syrjanen K, Pyrhonen S. Oncoprotein Bcl-2 and microsatellite instability are associated with disease-free survival and treatment response in colorectal cancer. Oncol Rep. 2008;20:999-1004 pubmed
- Li M, Liu L, Wang Z, Wang L, Liu Z, Xu G, et al. Overexpression of hMSH2 and hMLH1 protein in certain gastric cancers and their surrounding mucosae. Oncol Rep. 2008;19:401-6 pubmed
- Yoon S, Ku J, Shin Y, Kim K, Choi J, Jang E, et al. Hereditary nonpolyposis colorectal cancer in endometrial cancer patients. Int J Cancer. 2008;122:1077-81 pubmed
- Bendardaf R, Lamlum H, Ristamaki R, Korkeila E, Syrjanen K, Pyrhonen S. Thymidylate synthase and microsatellite instability in colorectal cancer: implications for disease free survival, treatment response and survival with metastases. Acta Oncol. 2008;47:1046-53 pubmed
- Taylor N, Zighelboim I, Huettner P, Powell M, Gibb R, Rader J, et al. DNA mismatch repair and TP53 defects are early events in uterine carcinosarcoma tumorigenesis. Mod Pathol. 2006;19:1333-8 pubmed
- Edelmann J, Richter K, Hanel C, Hering S, Horn L. X chromosomal and autosomal loss of heterozygosity and microsatellite instability in human cervical carcinoma. Int J Gynecol Cancer. 2006;16:1248-53 pubmed
- Kerber R, Neklason D, Samowitz W, Burt R. Frequency of familial colon cancer and hereditary nonpolyposis colorectal cancer (Lynch syndrome) in a large population database. Fam Cancer. 2005;4:239-44 pubmed
- Chen Z, Ritter J, Wang H. Differential expression of alpha-methylacyl coenzyme A racemase in adenocarcinomas of the small and large intestines. Am J Surg Pathol. 2005;29:890-6 pubmed
- Ricciardiello L, Ceccarelli C, Angiolini G, Pariali M, Chieco P, Paterini P, et al. High thymidylate synthase expression in colorectal cancer with microsatellite instability: implications for chemotherapeutic strategies. Clin Cancer Res. 2005;11:4234-40 pubmed
- Aust D, Haase M, Dobryden L, Markwarth A, Löhrs U, Wittekind C, et al. Mutations of the BRAF gene in ulcerative colitis-related colorectal carcinoma. Int J Cancer. 2005;115:673-7 pubmed
- Charara M, Edmonston T, Burkholder S, Walters R, Anne P, Mitchell E, et al. Microsatellite status and cell cycle associated markers in rectal cancer patients undergoing a combined regimen of 5-FU and CPT-11 chemotherapy and radiotherapy. Anticancer Res. 2004;24:3161-7 pubmed
- Boman B, Walters R, Fields J, Kovatich A, Zhang T, Isenberg G, et al. Colonic crypt changes during adenoma development in familial adenomatous polyposis: immunohistochemical evidence for expansion of the crypt base cell population. Am J Pathol. 2004;165:1489-98 pubmed
- Buttin B, Powell M, Mutch D, Rader J, Herzog T, Gibb R, et al. Increased risk for hereditary nonpolyposis colorectal cancer-associated synchronous and metachronous malignancies in patients with microsatellite instability-positive endometrial carcinoma lacking MLH1 promoter methylation. Clin Cancer Res. 2004;10:481-90 pubmed
articles
contribute
- If you are aware of any publication with knockout studies validating a monoclonal or recombinant antibody, either purchased from a supplier or developed by the author(s), please notify us through feedback.
questions and comments