This is a Validated Antibody Database (VAD) review about mouse Mre11a, based on 36 published articles (read how Labome selects the articles), using Mre11a antibody in all methods. It is aimed to help Labome visitors find the most suited Mre11a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Mre11a synonym: Mre11; Mre11b

GeneTex
mouse monoclonal (12D7)
  • immunocytochemistry; human; 1:500; loading ...; fig 4e
GeneTex Mre11a antibody (GeneTex, GTX70212) was used in immunocytochemistry on human samples at 1:500 (fig 4e). Nucleic Acids Res (2021) ncbi
mouse monoclonal (12D7)
  • western blot; human; loading ...; fig 4c
GeneTex Mre11a antibody (GeneTex, GTX70212) was used in western blot on human samples (fig 4c). Cell Host Microbe (2017) ncbi
mouse monoclonal (12D7)
  • western blot; human; loading ...; fig s2b
In order to test whether the attenuation of non-homologous end joining repair is sufficient to compromise homologous recombination in DEK knockout mice, GeneTex Mre11a antibody (GeneTex, GTX70212) was used in western blot on human samples (fig s2b). Sci Rep (2017) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; fig 2
In order to study how the Fanconi anemia pathway promotes homologous recombination at stalled replication forks, GeneTex Mre11a antibody (GeneTex, GTX70212) was used in immunocytochemistry on human samples (fig 2). Nucleic Acids Res (2016) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; fig 6
GeneTex Mre11a antibody (Genetex, GTX70212) was used in immunocytochemistry on human samples (fig 6). Viruses (2015) ncbi
mouse monoclonal (12D7)
  • western blot; human; fig 5
GeneTex Mre11a antibody (GeneTex, GTX70212) was used in western blot on human samples (fig 5). BMC Biol (2015) ncbi
mouse monoclonal (12D7)
  • western blot; human; fig 4
GeneTex Mre11a antibody (GeneTex, GTX70212) was used in western blot on human samples (fig 4). PLoS ONE (2015) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; 1:200; fig s6c
In order to assess the functionality of BRCA1 in the heterozygous state, GeneTex Mre11a antibody (Genetex, GTX70212) was used in immunocytochemistry on human samples at 1:200 (fig s6c). Nat Commun (2014) ncbi
mouse monoclonal (12D7)
  • western blot; human; fig 3
GeneTex Mre11a antibody (GeneTex, GTX70212) was used in western blot on human samples (fig 3). Oncogene (2015) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; mouse; 1:100; fig s3
GeneTex Mre11a antibody (GeneTex, GTX70212) was used in immunocytochemistry on mouse samples at 1:100 (fig s3). FASEB J (2014) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; fig 2d
  • western blot; human; fig 6a
GeneTex Mre11a antibody (GeneTex, GTX70212) was used in immunocytochemistry on human samples (fig 2d) and in western blot on human samples (fig 6a). Mol Cell (2014) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; 1:1000; fig 5
GeneTex Mre11a antibody (GeneTex, GTX70212) was used in immunocytochemistry on human samples at 1:1000 (fig 5). J Virol (2011) ncbi
mouse monoclonal (12D7)
  • western blot; human
GeneTex Mre11a antibody (GeneTex, #GTX70212) was used in western blot on human samples . Cancer Res (2011) ncbi
mouse monoclonal (12D7)
  • western blot; human
GeneTex Mre11a antibody (Genetex, GTX70212) was used in western blot on human samples . Cell Cycle (2010) ncbi
Abcam
mouse monoclonal (12D7)
  • western blot; human; 1:1000; loading ...; fig 1s1d
Abcam Mre11a antibody (abcam, ab214) was used in western blot on human samples at 1:1000 (fig 1s1d). elife (2020) ncbi
mouse monoclonal (12D7)
  • western blot; human; loading ...; fig s9a
  • western blot; mouse; loading ...; fig 4a
Abcam Mre11a antibody (Abcam, ab214) was used in western blot on human samples (fig s9a) and in western blot on mouse samples (fig 4a). Nat Struct Mol Biol (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
Abcam Mre11a antibody (Abcam, ab33125) was used in western blot on human samples (fig 4). Nucleic Acids Res (2016) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; fig 3
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 1
Abcam Mre11a antibody (Abcam, ab33125) was used in immunoprecipitation on human samples (fig 3), in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 1). BMC Cancer (2016) ncbi
mouse monoclonal (12D7)
  • immunoprecipitation; human; fig 5a
Abcam Mre11a antibody (Abcam, ab214) was used in immunoprecipitation on human samples (fig 5a). Nat Commun (2015) ncbi
mouse monoclonal (12D7)
  • western blot; human; fig s1c
  • western blot; mouse; fig 5a
Abcam Mre11a antibody (Abcam, ab214) was used in western blot on human samples (fig s1c) and in western blot on mouse samples (fig 5a). Cell Death Differ (2016) ncbi
mouse monoclonal (12D7)
  • western blot; human; 1:500; fig s2
Abcam Mre11a antibody (Abcam, ab214) was used in western blot on human samples at 1:500 (fig s2). Nat Cell Biol (2014) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; mouse
Abcam Mre11a antibody (Abcam, ab214) was used in immunocytochemistry on mouse samples . PLoS ONE (2014) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; 1:200 and 1:750
  • western blot; human
Abcam Mre11a antibody (Abcam, ab214) was used in immunocytochemistry on human samples at 1:200 and 1:750 and in western blot on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (12D7)
  • western blot; human
Abcam Mre11a antibody (Abcam, AB214) was used in western blot on human samples . Oncotarget (2014) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; 1:1000
  • western blot; human; 1:500-1:1000
Abcam Mre11a antibody (Abcam, ab214) was used in immunocytochemistry on human samples at 1:1000 and in western blot on human samples at 1:500-1:1000. PLoS ONE (2013) ncbi
mouse monoclonal (12D7)
  • immunohistochemistry - paraffin section; human; 1:200
Abcam Mre11a antibody (Abcam, ab214) was used in immunohistochemistry - paraffin section on human samples at 1:200. World J Gastroenterol (2013) ncbi
Novus Biologicals
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; 1:5000; loading ...; fig s1a
  • ChIP-Seq; mouse; loading ...; fig s3a
  • western blot; mouse; 1:5000; loading ...; fig s1a, s1b
Novus Biologicals Mre11a antibody (Novus, NB100-142) was used in western blot on human samples at 1:5000 (fig s1a), in ChIP-Seq on mouse samples (fig s3a) and in western blot on mouse samples at 1:5000 (fig s1a, s1b). Science (2019) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; 1:1000; loading ...; fig s2f
Novus Biologicals Mre11a antibody (Novus Biological, NB100-C142) was used in western blot on human samples at 1:1000 (fig s2f). Nucleic Acids Res (2019) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunocytochemistry; human; loading ...; fig s5l
  • western blot; human; loading ...; fig s5a
Novus Biologicals Mre11a antibody (Novus, NB 100-142) was used in immunocytochemistry on human samples (fig s5l) and in western blot on human samples (fig s5a). Cell (2019) ncbi
Santa Cruz Biotechnology
mouse monoclonal (18)
  • immunocytochemistry; mouse; 1:500; loading ...; fig s9a
  • western blot; mouse; 1:100; loading ...; fig s13a
  • western blot; human; 1:100; loading ...; fig s12e
Santa Cruz Biotechnology Mre11a antibody (Santa Cruz, SC-135992) was used in immunocytochemistry on mouse samples at 1:500 (fig s9a), in western blot on mouse samples at 1:100 (fig s13a) and in western blot on human samples at 1:100 (fig s12e). Science (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; loading ...
Cell Signaling Technology Mre11a antibody (Cell Signalling Technologies, 4895S) was used in western blot on human samples . elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology Mre11a antibody (Cell Signaling, 4895S) was used in western blot on human samples at 1:1000 (fig 2). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology Mre11a antibody (Cell Signaling, 4895) was used in western blot on human samples (fig 1). Mol Cancer Res (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 6
Cell Signaling Technology Mre11a antibody (Cell Signaling Technology, 4895) was used in western blot on mouse samples (fig 6). Oncogene (2016) ncbi
BD Biosciences
mouse monoclonal (18/MRE11)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences Mre11a antibody (BD, 18) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (18/MRE11)
  • western blot; human; 1:1000; fig 3
BD Biosciences Mre11a antibody (BD Biosciences, 611366) was used in western blot on human samples at 1:1000 (fig 3). Nucleic Acids Res (2016) ncbi
Articles Reviewed
  1. Suzuki R, Murata M, Manguso N, Watanabe T, Mouakkad Montoya L, Igari F, et al. The fragility of a structurally diverse duplication block triggers recurrent genomic amplification. Nucleic Acids Res. 2021;49:244-256 pubmed publisher
  2. Lochab S, Singh Y, Sengupta S, Nandicoori V. Mycobacterium tuberculosis exploits host ATM kinase for survival advantage through SecA2 secretome. elife. 2020;9: pubmed publisher
  3. Onn L, Portillo M, Ilic S, Cleitman G, Stein D, Kaluski S, et al. SIRT6 is a DNA double-strand break sensor. elife. 2020;9: pubmed publisher
  4. Wienert B, Wyman S, Richardson C, Yeh C, Akçakaya P, Porritt M, et al. Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq. Science. 2019;364:286-289 pubmed publisher
  5. Alfano L, Caporaso A, Altieri A, Dell Aquila M, Landi C, Bini L, et al. Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation. Nucleic Acids Res. 2019;47:4068-4085 pubmed publisher
  6. Jachimowicz R, Beleggia F, Isensee J, Velpula B, Goergens J, Bustos M, et al. UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell. 2019;176:505-519.e22 pubmed publisher
  7. Lei L, Chen H, Xue W, Yang B, Hu B, Wei J, et al. APOBEC3 induces mutations during repair of CRISPR-Cas9-generated DNA breaks. Nat Struct Mol Biol. 2018;25:45-52 pubmed publisher
  8. Meyerson N, Zhou L, Guo Y, Zhao C, Tao Y, Krug R, et al. Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation. Cell Host Microbe. 2017;22:627-638.e7 pubmed publisher
  9. Smith E, Gole B, Willis N, Soria R, Starnes L, Krumpelbeck E, et al. DEK is required for homologous recombination repair of DNA breaks. Sci Rep. 2017;7:44662 pubmed publisher
  10. Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
  11. Sun Y, Zheng W, Guo Z, Ju Q, Zhu L, Gao J, et al. A novel TP53 pathway influences the HGS-mediated exosome formation in colorectal cancer. Sci Rep. 2016;6:28083 pubmed publisher
  12. Ahrabi S, Sarkar S, Pfister S, Pirovano G, Higgins G, Porter A, et al. A role for human homologous recombination factors in suppressing microhomology-mediated end joining. Nucleic Acids Res. 2016;44:5743-57 pubmed publisher
  13. Chang L, Huang J, Wang K, Li J, Yan R, Zhu L, et al. Targeting Rad50 sensitizes human nasopharyngeal carcinoma cells to radiotherapy. BMC Cancer. 2016;16:190 pubmed publisher
  14. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  15. Tookman L, Browne A, Connell C, Bridge G, Ingemarsdotter C, Dowson S, et al. RAD51 and BRCA2 Enhance Oncolytic Adenovirus Type 5 Activity in Ovarian Cancer. Mol Cancer Res. 2016;14:44-55 pubmed publisher
  16. Renaud E, Barascu A, Rosselli F. Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells. Nucleic Acids Res. 2016;44:648-56 pubmed publisher
  17. Ortega Atienza S, Wong V, Deloughery Z, Luczak M, Zhitkovich A. ATM and KAT5 safeguard replicating chromatin against formaldehyde damage. Nucleic Acids Res. 2016;44:198-209 pubmed publisher
  18. Clynes D, Jelinska C, Xella B, Ayyub H, Scott C, Mitson M, et al. Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX. Nat Commun. 2015;6:7538 pubmed publisher
  19. Wang J, Chen S, Sun C, Chien T, Chern Y. A central role of TRAX in the ATM-mediated DNA repair. Oncogene. 2016;35:1657-70 pubmed publisher
  20. Petroni M, Sardina F, Heil C, Sahún Roncero M, Colicchia V, Veschi V, et al. The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress. Cell Death Differ. 2016;23:197-206 pubmed publisher
  21. Hollingworth R, Skalka G, Stewart G, Hislop A, Blackbourn D, Grand R. Activation of DNA Damage Response Pathways during Lytic Replication of KSHV. Viruses. 2015;7:2908-27 pubmed publisher
  22. Harten S, Oey H, Bourke L, Bharti V, Isbel L, Daxinger L, et al. The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers. BMC Biol. 2015;13:21 pubmed publisher
  23. Nakajima N, Hagiwara Y, Oike T, Okayasu R, Murakami T, Nakano T, et al. Pre-exposure to ionizing radiation stimulates DNA double strand break end resection, promoting the use of homologous recombination repair. PLoS ONE. 2015;10:e0122582 pubmed publisher
  24. Pathania S, Bade S, Le Guillou M, Burke K, Reed R, Bowman Colin C, et al. BRCA1 haploinsufficiency for replication stress suppression in primary cells. Nat Commun. 2014;5:5496 pubmed publisher
  25. Hühn D, Kousholt A, Sørensen C, Sartori A. miR-19, a component of the oncogenic miR-17∼92 cluster, targets the DNA-end resection factor CtIP. Oncogene. 2015;34:3977-84 pubmed publisher
  26. Larsen D, Hari F, Clapperton J, Gwerder M, Gutsche K, Altmeyer M, et al. The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage. Nat Cell Biol. 2014;16:792-803 pubmed publisher
  27. Clynes D, Jelinska C, Xella B, Ayyub H, Taylor S, Mitson M, et al. ATRX dysfunction induces replication defects in primary mouse cells. PLoS ONE. 2014;9:e92915 pubmed publisher
  28. Becker A, Durante M, Taucher Scholz G, Jakob B. ATM alters the otherwise robust chromatin mobility at sites of DNA double-strand breaks (DSBs) in human cells. PLoS ONE. 2014;9:e92640 pubmed publisher
  29. Martin R, Kerr M, Teo M, Jevons S, Koritzinsky M, Wouters B, et al. Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours. Oncotarget. 2014;5:993-1003 pubmed
  30. Schröder Heurich B, Wieland B, Lavin M, Schindler D, Dork T. Protective role of RAD50 on chromatin bridges during abnormal cytokinesis. FASEB J. 2014;28:1331-41 pubmed publisher
  31. Shibata A, Moiani D, Arvai A, Perry J, Harding S, Genois M, et al. DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities. Mol Cell. 2014;53:7-18 pubmed publisher
  32. Birkenkamp Demtroder K, Hahn S, Mansilla F, Thorsen K, Maghnouj A, Christensen R, et al. Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells. PLoS ONE. 2013;8:e73593 pubmed publisher
  33. Zhang Z, Liu Y, Yin X, Zhan P, Gu Y, Ni X. Loss of BRCA1 expression leads to worse survival in patients with gastric carcinoma. World J Gastroenterol. 2013;19:1968-74 pubmed publisher
  34. Karen K, Hearing P. Adenovirus core protein VII protects the viral genome from a DNA damage response at early times after infection. J Virol. 2011;85:4135-42 pubmed publisher
  35. Anderson V, Walton M, Eve P, Boxall K, Antoni L, Caldwell J, et al. CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors. Cancer Res. 2011;71:463-72 pubmed publisher
  36. Guo Z, Deshpande R, Paull T. ATM activation in the presence of oxidative stress. Cell Cycle. 2010;9:4805-11 pubmed