This is a Validated Antibody Database (VAD) review about mouse Mgmt, based on 5 published articles (read how Labome selects the articles), using Mgmt antibody in all methods. It is aimed to help Labome visitors find the most suited Mgmt antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Mgmt synonym: AGT; AI267024; Agat; methylated-DNA--protein-cysteine methyltransferase; 6-O-methylguanine-DNA methyltransferase; O-6-alkylguanine-DNA alkyltransferase; O-6-methylguanine-DNA-alkyltransferase

Novus Biologicals
mouse monoclonal (MT 23.2)
  • immunohistochemistry; human; loading ...; fig s1b
In order to describe the mechanism behind the association between single nucleotide polymorphism rs55705857 and glioma development., Novus Biologicals Mgmt antibody (Novus Biologicals, NB100-168) was used in immunohistochemistry on human samples (fig s1b). Sci Rep (2016) ncbi
mouse monoclonal (MT 23.2)
  • western blot; human; fig 6
In order to determine the promotion of genomic and phenotypic changes in glioblastoma cells by temozolomide, Novus Biologicals Mgmt antibody (Novus Biologicals, NB100-168) was used in western blot on human samples (fig 6). Cancer Cell Int (2016) ncbi
mouse monoclonal (MT 23.2)
  • western blot; human; 1:1000; fig s1d
In order to investigate the role of protein stability in the choice of DNA repair mechanism, Novus Biologicals Mgmt antibody (Novus, NB100-168) was used in western blot on human samples at 1:1000 (fig s1d). Nat Commun (2014) ncbi
Abcam
mouse monoclonal (MT3.1)
  • immunohistochemistry; human; loading ...; fig s2
Abcam Mgmt antibody (Abcam, ab39253) was used in immunohistochemistry on human samples (fig s2). Cancer Lett (2015) ncbi
mouse monoclonal (MT3.1)
  • western blot; human; fig 3d, 3e, 3f
Abcam Mgmt antibody (Abcam, ab39253) was used in western blot on human samples (fig 3d, 3e, 3f). Int J Oncol (2014) ncbi
Articles Reviewed
  1. Oktay Y, Ãœlgen E, Can Ã, Akyerli C, Yüksel Å, Erdemgil Y, et al. IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. Sci Rep. 2016;6:27569 pubmed publisher
  2. Stepanenko A, Andreieva S, Korets K, Mykytenko D, Baklaushev V, Huleyuk N, et al. Temozolomide promotes genomic and phenotypic changes in glioblastoma cells. Cancer Cell Int. 2016;16:36 pubmed publisher
  3. Chen T, Cho H, Wang W, Nguyen J, Jhaveri N, Rosenstein Sisson R, et al. A novel temozolomide analog, NEO212, with enhanced activity against MGMT-positive melanoma in vitro and in vivo. Cancer Lett. 2015;358:144-51 pubmed publisher
  4. Fang Q, Inanç B, Schamus S, Wang X, Wei L, Brown A, et al. HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β. Nat Commun. 2014;5:5513 pubmed publisher
  5. Okada M, Sato A, Shibuya K, Watanabe E, Seino S, Suzuki S, et al. JNK contributes to temozolomide resistance of stem-like glioblastoma cells via regulation of MGMT expression. Int J Oncol. 2014;44:591-9 pubmed publisher