This is a Validated Antibody Database (VAD) review about mouse Mfge8, based on 4 published articles (read how Labome selects the articles), using Mfge8 antibody in all methods. It is aimed to help Labome visitors find the most suited Mfge8 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Mfge8 synonym: AA408458; AI325141; MFG-E8; MP47; Mfgm; P47; SED1; lactadherin

Knockout validation
MBL International
(18A2-G10)
  • immunohistochemistry knockout validation; mouse; 1:200; loading ...; fig 7a
  • western blot; mouse; 1:2000; loading ...; fig 3b
In order to observe that cardiac myofibroblasts efficiently engulf dead cells, MBL International Mfge8 antibody (MBL, 18A2-G10) was used in immunohistochemistry knockout validation on mouse samples at 1:200 (fig 7a) and in western blot on mouse samples at 1:2000 (fig 3b). J Clin Invest (2017) ncbi
R&D Systems
rat monoclonal (340614)
  • flow cytometry; mouse; 1:500; loading ...; fig 1g
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 1f, 1h
R&D Systems Mfge8 antibody (R&D, MAB2805) was used in flow cytometry on mouse samples at 1:500 (fig 1g) and in immunohistochemistry on mouse samples at 1:1000 (fig 1f, 1h). elife (2019) ncbi
MBL International
(18A2-G10)
  • western blot; mouse; fig 2a
In order to describe extracellular vesicle subpopulations secreted by fat cells, MBL International Mfge8 antibody (MBL, D199-3) was used in western blot on mouse samples (fig 2a). J Extracell Vesicles (2017) ncbi
(18A2-G10)
  • immunohistochemistry knockout validation; mouse; 1:200; loading ...; fig 7a
  • western blot; mouse; 1:2000; loading ...; fig 3b
In order to observe that cardiac myofibroblasts efficiently engulf dead cells, MBL International Mfge8 antibody (MBL, 18A2-G10) was used in immunohistochemistry knockout validation on mouse samples at 1:200 (fig 7a) and in western blot on mouse samples at 1:2000 (fig 3b). J Clin Invest (2017) ncbi
(18A2-G10)
  • immunohistochemistry; mouse; 1:250; fig 2
In order to study the role of microglial phagocytosis of living photoreceptors in retinal degeneration, MBL International Mfge8 antibody (MBL, D199-3) was used in immunohistochemistry on mouse samples at 1:250 (fig 2). EMBO Mol Med (2015) ncbi
Articles Reviewed
  1. Park C, Kehrl J. An integrin/MFG-E8 shuttle loads HIV-1 viral-like particles onto follicular dendritic cells in mouse lymph node. elife. 2019;8: pubmed publisher
  2. Durcin M, Fleury A, Taillebois E, Hilairet G, Krupova Z, Henry C, et al. Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles. J Extracell Vesicles. 2017;6:1305677 pubmed publisher
  3. Nakaya M, Watari K, Tajima M, Nakaya T, Matsuda S, Ohara H, et al. Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction. J Clin Invest. 2017;127:383-401 pubmed publisher
  4. Zhao L, Zabel M, Wang X, Ma W, Shah P, Fariss R, et al. Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration. EMBO Mol Med. 2015;7:1179-97 pubmed publisher