This is a Validated Antibody Database (VAD) review about mouse Mertk, based on 21 published articles (read how Labome selects the articles), using Mertk antibody in all methods. It is aimed to help Labome visitors find the most suited Mertk antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Mertk synonym: Eyk; Mer; Nyk; nmf12

Knockout validation
Invitrogen
rat monoclonal (DS5MMER)
  • western blot knockout validation; mouse; loading ...; fig 2c
Invitrogen Mertk antibody (Invitrogen, 16-5751-85) was used in western blot knockout validation on mouse samples (fig 2c). Cell Death Dis (2021) ncbi
Invitrogen
rat monoclonal (DS5MMER)
  • flow cytometry; mouse; loading ...; fig s3d
Invitrogen Mertk antibody (Thermo Fisher, DS5MMER) was used in flow cytometry on mouse samples (fig s3d). Front Immunol (2021) ncbi
rat monoclonal (DS5MMER)
  • western blot knockout validation; mouse; loading ...; fig 2c
Invitrogen Mertk antibody (Invitrogen, 16-5751-85) was used in western blot knockout validation on mouse samples (fig 2c). Cell Death Dis (2021) ncbi
rat monoclonal (DS5MMER)
  • immunohistochemistry; human; 1:200; loading ...; fig 1c
Invitrogen Mertk antibody (eBioscience, DS5MMER) was used in immunohistochemistry on human samples at 1:200 (fig 1c). Nat Immunol (2021) ncbi
rat monoclonal (DS5MMER)
  • flow cytometry; mouse; loading ...; fig 4c
Invitrogen Mertk antibody (eBioscience, DS5MMER) was used in flow cytometry on mouse samples (fig 4c). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig s7b
Invitrogen Mertk antibody (ThermoFisher, PA5-40270) was used in western blot on mouse samples at 1:2000 (fig s7b). Nat Commun (2020) ncbi
rat monoclonal (DS5MMER)
  • flow cytometry; mouse; loading ...
Invitrogen Mertk antibody (Thermo Fisher Scientific, DS5MMER) was used in flow cytometry on mouse samples . Sci Adv (2020) ncbi
rat monoclonal (DS5MMER)
  • flow cytometry; mouse; loading ...
Invitrogen Mertk antibody (Thermo Fisher Scientific, DS5MMER) was used in flow cytometry on mouse samples . BMC Pulm Med (2020) ncbi
rat monoclonal (DS5MMER)
  • flow cytometry; mouse; loading ...
Invitrogen Mertk antibody (Thermo Fisher Scientific, DS5MMER) was used in flow cytometry on mouse samples . Arthritis Res Ther (2020) ncbi
rat monoclonal (DS5MMER)
  • flow cytometry; mouse; loading ...
Invitrogen Mertk antibody (Thermo Fisher Scientific, DS5MMER) was used in flow cytometry on mouse samples . Antioxidants (Basel) (2020) ncbi
rat monoclonal (DS5MMER)
  • flow cytometry; mouse; 1:200; loading ...; fig s4, s5a-c
Invitrogen Mertk antibody (eBioscience, 25-5751-82) was used in flow cytometry on mouse samples at 1:200 (fig s4, s5a-c). Nat Commun (2020) ncbi
rat monoclonal (DS5MMER)
  • flow cytometry; mouse; loading ...; fig 1a
Invitrogen Mertk antibody (eBioscience, 12-5751-80) was used in flow cytometry on mouse samples (fig 1a). Cell Commun Signal (2018) ncbi
rat monoclonal (DS5MMER)
  • flow cytometry; mouse; loading ...; fig 1b
Invitrogen Mertk antibody (eBioscience, DS5MMER) was used in flow cytometry on mouse samples (fig 1b). J Exp Med (2018) ncbi
rat monoclonal (DS5MMER)
  • flow cytometry; mouse; loading ...; fig 5a
In order to show that the MEK1/2 pathway is a key regulator of macrophage reparative properties, Invitrogen Mertk antibody (eBioscience, DS5MMER) was used in flow cytometry on mouse samples (fig 5a). J Immunol (2017) ncbi
rat monoclonal (DS5MMER)
  • flow cytometry; mouse; 1:100; fig s3
Invitrogen Mertk antibody (eBioscience, 12-5751-82) was used in flow cytometry on mouse samples at 1:100 (fig s3). PLoS Pathog (2016) ncbi
rat monoclonal (DS5MMER)
  • flow cytometry; mouse; loading ...; fig s1a
In order to report that monocytes and natural killer cells via the DNAM-1-PVR pathway control mouse cytomegalovirus infection, Invitrogen Mertk antibody (eBiosciences, DS5MMER) was used in flow cytometry on mouse samples (fig s1a). J Exp Med (2016) ncbi
BioLegend
rat monoclonal (2B10C42)
  • mass cytometry; mouse; loading ...; fig s2
BioLegend Mertk antibody (BioLegend, 151503) was used in mass cytometry on mouse samples (fig s2). Front Immunol (2021) ncbi
rat monoclonal (2B10C42)
  • flow cytometry; mouse; 1:100; loading ...; fig 1l
BioLegend Mertk antibody (BioLegend, 151504) was used in flow cytometry on mouse samples at 1:100 (fig 1l). elife (2021) ncbi
rat monoclonal (2B10C42)
  • flow cytometry; mouse; loading ...; fig 2a
BioLegend Mertk antibody (BioLegend, 151506) was used in flow cytometry on mouse samples (fig 2a). J Clin Invest (2018) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-1)
  • western blot; human; 1:2000; loading ...; fig 7d
Santa Cruz Biotechnology Mertk antibody (Santa Cruz Biotechnology, sc-365499) was used in western blot on human samples at 1:2000 (fig 7d). elife (2019) ncbi
mouse monoclonal (B-1)
  • western blot; human; 1:1000; loading ...; fig 6b
In order to identify conditions in which low-passage ARPE-19 cells express genes specific to native human RPE cells, Santa Cruz Biotechnology Mertk antibody (Santa Cruz, SC-365499) was used in western blot on human samples at 1:1000 (fig 6b). Mol Vis (2017) ncbi
R&D Systems
domestic goat polyclonal
  • immunohistochemistry; human; 1:200; loading ...; fig 1c
R&D Systems Mertk antibody (R&D, AF591) was used in immunohistochemistry on human samples at 1:200 (fig 1c). Nat Immunol (2021) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4d
In order to engineer and characterize a second-generation, high-affinity AXL decoy receptor, Abcam Mertk antibody (Abcam, ab14921) was used in western blot on mouse samples (fig 4d). J Clin Invest (2017) ncbi
Articles Reviewed
  1. Bhattacharjee O, Ayyangar U, Kurbet A, Lakshmanan V, Palakodeti D, Ginhoux F, et al. Epithelial-Macrophage Crosstalk Initiates Sterile Inflammation in Embryonic Skin. Front Immunol. 2021;12:718005 pubmed publisher
  2. Félix I, Jokela H, Karhula J, Kotaja N, Savontaus E, Salmi M, et al. Single-Cell Proteomics Reveals the Defined Heterogeneity of Resident Macrophages in White Adipose Tissue. Front Immunol. 2021;12:719979 pubmed publisher
  3. Ryu S, Shchukina I, Youm Y, Qing H, Hilliard B, Dlugos T, et al. Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice. elife. 2021;10: pubmed publisher
  4. Al Zaeed N, Budai Z, Szondy Z, Sarang Z. TAM kinase signaling is indispensable for proper skeletal muscle regeneration in mice. Cell Death Dis. 2021;12:611 pubmed publisher
  5. Huang Y, Happonen K, Burrola P, O Connor C, Hah N, Huang L, et al. Microglia use TAM receptors to detect and engulf amyloid β plaques. Nat Immunol. 2021;22:586-594 pubmed publisher
  6. Manils J, Webb L, Howes A, Janzen J, Boeing S, Bowcock A, et al. CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation. elife. 2020;9: pubmed publisher
  7. Lechertier T, Reynolds L, Kim H, Pedrosa A, Gómez Escudero J, Muñoz Félix J, et al. Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth. Nat Commun. 2020;11:2810 pubmed publisher
  8. Wang S, Li R, Ng T, Luthria G, Oudin M, Prytyskach M, et al. Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy. Sci Adv. 2020;6:eaaz8521 pubmed publisher
  9. Te H, Perlman D, Shenoy C, Steinberger D, Cogswell R, Roukoz H, et al. Clinical characteristics and organ system involvement in sarcoidosis: comparison of the University of Minnesota Cohort with other cohorts. BMC Pulm Med. 2020;20:155 pubmed publisher
  10. Lee K, Zhang Z, Achuthan A, Fleetwood A, Smith J, Hamilton J, et al. IL-23 in arthritic and inflammatory pain development in mice. Arthritis Res Ther. 2020;22:123 pubmed publisher
  11. Woo Y, Lim J, Oh J, Lee J, Kim J. Neuroprotective Effects of Euonymus alatus Extract on Scopolamine-Induced Memory Deficits in Mice. Antioxidants (Basel). 2020;9: pubmed publisher
  12. Aslan K, Turco V, Blobner J, Sonner J, Liuzzi A, Núñez N, et al. Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas. Nat Commun. 2020;11:931 pubmed publisher
  13. Xu H, Xu S, Xie S, Zhang Y, Yang J, Zhang W, et al. MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathway. elife. 2019;8: pubmed publisher
  14. Zhou J, Yang A, Wang Y, Chen F, Zhao Z, Davra V, et al. Tyro3, Axl, and Mertk receptors differentially participate in platelet activation and thrombus formation. Cell Commun Signal. 2018;16:98 pubmed publisher
  15. Ubil E, Caskey L, Holtzhausen A, Hunter D, Story C, Earp H. Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response. J Clin Invest. 2018;128:2356-2369 pubmed publisher
  16. Huang L, Nazarova E, Tan S, Liu Y, Russell D. Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogeny. J Exp Med. 2018;215:1135-1152 pubmed publisher
  17. Samuel W, Jaworski C, Postnikova O, Kutty R, Duncan T, Tan L, et al. Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. Mol Vis. 2017;23:60-89 pubmed
  18. Long M, Eddy W, Gong K, Lovelace Macon L, McMahan R, Charron J, et al. MEK1/2 Inhibition Promotes Macrophage Reparative Properties. J Immunol. 2017;198:862-872 pubmed publisher
  19. Kariolis M, Miao Y, Diep A, Nash S, Olcina M, Jiang D, et al. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest. 2017;127:183-198 pubmed publisher
  20. Meliopoulos V, Van De Velde L, Van De Velde N, Karlsson E, Neale G, Vogel P, et al. An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens. PLoS Pathog. 2016;12:e1005804 pubmed publisher
  21. Lenac Rovis T, Kucan Brlic P, Kaynan N, Juranic Lisnic V, Brizic I, Jordan S, et al. Inflammatory monocytes and NK cells play a crucial role in DNAM-1-dependent control of cytomegalovirus infection. J Exp Med. 2016;213:1835-50 pubmed publisher