This is a Validated Antibody Database (VAD) review about mouse Mdc1, based on 5 published articles (read how Labome selects the articles), using Mdc1 antibody in all methods. It is aimed to help Labome visitors find the most suited Mdc1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Mdc1 synonym: 6820401C03; AA413496; Nfbd1; mKIAA0170; mediator of DNA damage checkpoint protein 1; mediation of DNA damage checkpoint 1

Knockout validation
EMD Millipore
mouse monoclonal (P2B11)
  • western blot knockout validation; human; 1:1000; loading ...; fig 1g
  • immunocytochemistry; human; 1:1000; loading ...; fig 1f
EMD Millipore Mdc1 antibody (Millipore, 05-1572) was used in western blot knockout validation on human samples at 1:1000 (fig 1g) and in immunocytochemistry on human samples at 1:1000 (fig 1f). Nat Commun (2018) ncbi
Novus Biologicals
rabbit polyclonal
  • immunohistochemistry; human; fig 5
  • western blot; human; fig 6
Novus Biologicals Mdc1 antibody (Novus, NB100-395) was used in immunohistochemistry on human samples (fig 5) and in western blot on human samples (fig 6). PLoS ONE (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human; fig 5
Novus Biologicals Mdc1 antibody (Novus Biologicals, NB100-395) was used in immunocytochemistry on human samples (fig 5). Nucleic Acids Res (2016) ncbi
EMD Millipore
mouse monoclonal (P2B11)
  • western blot knockout validation; human; 1:1000; loading ...; fig 1g
  • immunocytochemistry; human; 1:1000; loading ...; fig 1f
EMD Millipore Mdc1 antibody (Millipore, 05-1572) was used in western blot knockout validation on human samples at 1:1000 (fig 1g) and in immunocytochemistry on human samples at 1:1000 (fig 1f). Nat Commun (2018) ncbi
mouse monoclonal (P2B11)
  • immunocytochemistry; mouse; loading ...; fig 2d
EMD Millipore Mdc1 antibody (Millipore, P2B11) was used in immunocytochemistry on mouse samples (fig 2d). Genes Dev (2017) ncbi
mouse monoclonal (P2B11)
  • immunocytochemistry; human; 1:500; fig s1
EMD Millipore Mdc1 antibody (Millipore, 05-1572) was used in immunocytochemistry on human samples at 1:500 (fig s1). Mol Biol Cell (2015) ncbi
Articles Reviewed
  1. Nowsheen S, Aziz K, Luo K, Deng M, Qin B, Yuan J, et al. ZNF506-dependent positive feedback loop regulates H2AX signaling after DNA damage. Nat Commun. 2018;9:2736 pubmed publisher
  2. Gong Y, Handa N, Kowalczykowski S, de Lange T. PHF11 promotes DSB resection, ATR signaling, and HR. Genes Dev. 2017;31:46-58 pubmed publisher
  3. Ge C, Che L, Du C. The UBC Domain Is Required for BRUCE to Promote BRIT1/MCPH1 Function in DSB Signaling and Repair Post Formation of BRUCE-USP8-BRIT1 Complex. PLoS ONE. 2015;10:e0144957 pubmed publisher
  4. Saquilabon Cruz G, Kong X, Silva B, Khatibzadeh N, Thai R, Berns M, et al. Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites. Nucleic Acids Res. 2016;44:e27 pubmed publisher
  5. Mackay D, Ullman K. ATR and a Chk1-Aurora B pathway coordinate postmitotic genome surveillance with cytokinetic abscission. Mol Biol Cell. 2015;26:2217-26 pubmed publisher