This is a Validated Antibody Database (VAD) review about mouse Mcam, based on 40 published articles (read how Labome selects the articles), using Mcam antibody in all methods. It is aimed to help Labome visitors find the most suited Mcam antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Mcam synonym: 1-gicerin; AV025631; CD146; CD149; Muc18; s-endo; s-gicerin

Knockout validation
Abcam
domestic rabbit monoclonal (EPR3208)
  • western blot knockout validation; mouse; loading ...; fig 4e, 7f
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 5k
Abcam Mcam antibody (Abcam, ab75769) was used in western blot knockout validation on mouse samples (fig 4e, 7f) and in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 5k). Lab Invest (2022) ncbi
BioLegend
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; 1:100; loading ...; fig s7-2b
BioLegend Mcam antibody (Biolegend, 134704) was used in flow cytometry on mouse samples at 1:100 (fig s7-2b). elife (2022) ncbi
rat monoclonal (ME-9F1)
  • immunohistochemistry; mouse; 1:300
BioLegend Mcam antibody (Biolegend, 134701) was used in immunohistochemistry on mouse samples at 1:300. Nat Cell Biol (2022) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; loading ...; fig 1c
BioLegend Mcam antibody (Biolegend, ME-9F1) was used in flow cytometry on mouse samples (fig 1c). Cell Mol Gastroenterol Hepatol (2022) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; loading ...; fig 2b
BioLegend Mcam antibody (BioLegend, ME-9F1) was used in flow cytometry on mouse samples (fig 2b). Sci Rep (2021) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; 1:100; loading ...; fig 3c
BioLegend Mcam antibody (BioLegend, 134713) was used in flow cytometry on mouse samples at 1:100 (fig 3c). elife (2021) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; loading ...; fig ex1e
BioLegend Mcam antibody (BioLegend, ME-9F1) was used in flow cytometry on mouse samples (fig ex1e). Nature (2019) ncbi
rat monoclonal (ME-9F1)
BioLegend Mcam antibody (BioLegend, ME-9F1) was used . J Neuroinflammation (2018) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; loading ...; fig 4a
BioLegend Mcam antibody (Biolegend, ME-9F1) was used in flow cytometry on mouse samples (fig 4a). J Immunol (2018) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; 1:25; loading ...; fig s1g
BioLegend Mcam antibody (BioLegend, 134705) was used in flow cytometry on mouse samples at 1:25 (fig s1g). Leukemia (2018) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; loading ...; fig 2j
In order to investigate the similarity between interferon gamma-induced tumor ischemia and physiological blood vessel regression, BioLegend Mcam antibody (BioLegend, 134704) was used in flow cytometry on mouse samples (fig 2j). Nature (2017) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; fig s4a
BioLegend Mcam antibody (BioLegend, 134713) was used in flow cytometry on mouse samples (fig s4a). J Cell Sci (2017) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; tbl s1
In order to report that Tbx18 selectively marks pericytes and vascular smooth muscle cells, BioLegend Mcam antibody (BioLegend, 134704) was used in flow cytometry on mouse samples (tbl s1). Cell Stem Cell (2017) ncbi
rat monoclonal (ME-9F1)
In order to study the role of CD146 in the formation and retention of macrophage foam cells, BioLegend Mcam antibody (Biolegend, 134701) was used . Cell Res (2017) ncbi
rat monoclonal (ME-9F1)
BioLegend Mcam antibody (BioLegend, 134705) was used . Nat Commun (2016) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; loading ...; fig 1b
In order to test if Mincle signaling drives intrahepatic inflammation and liver injury in Con A hepatitis, BioLegend Mcam antibody (BioLegend, ME-9F1) was used in flow cytometry on mouse samples (fig 1b). J Immunol (2016) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; loading ...; fig 2
BioLegend Mcam antibody (Biolegend, ME-9F1) was used in flow cytometry on mouse samples (fig 2). J Immunol (2016) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; fig 1a
In order to identify the origin of activated fibroblasts, BioLegend Mcam antibody (BioLegend, ME-9F1) was used in flow cytometry on mouse samples (fig 1a). Am J Pathol (2015) ncbi
Abcam
domestic rabbit monoclonal (EPR3208)
  • western blot knockout validation; mouse; loading ...; fig 4e, 7f
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 5k
Abcam Mcam antibody (Abcam, ab75769) was used in western blot knockout validation on mouse samples (fig 4e, 7f) and in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 5k). Lab Invest (2022) ncbi
domestic rabbit monoclonal (EPR3208)
  • immunohistochemistry; rat; 1:100; loading ...; fig 2
Abcam Mcam antibody (Abcam, ab75769) was used in immunohistochemistry on rat samples at 1:100 (fig 2). Int J Mol Sci (2021) ncbi
domestic rabbit monoclonal (EPR3208)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s3b
Abcam Mcam antibody (Abcam, ab75769) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig s3b). Sci Signal (2021) ncbi
domestic rabbit monoclonal (EPR3208)
  • immunohistochemistry; human; 1:100
Abcam Mcam antibody (Abcam, ab75769) was used in immunohistochemistry on human samples at 1:100. elife (2020) ncbi
domestic rabbit monoclonal (EPR3208)
  • western blot; mouse; 1:1000; loading ...; fig 1b, 1d
Abcam Mcam antibody (Abcam, ab75769) was used in western blot on mouse samples at 1:1000 (fig 1b, 1d). Front Immunol (2020) ncbi
mouse monoclonal (P1H12)
  • immunocytochemistry; human; loading ...; fig 2a
Abcam Mcam antibody (Abcam, ab78451) was used in immunocytochemistry on human samples (fig 2a). J Clin Med (2020) ncbi
domestic rabbit monoclonal (EPR3208)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2d
Abcam Mcam antibody (Abcam, EPR3208) was used in immunohistochemistry - paraffin section on mouse samples (fig 2d). J Neuroinflammation (2018) ncbi
mouse monoclonal (P1H12)
  • immunohistochemistry; human; loading ...; fig 1c
  • immunohistochemistry; mouse; loading ...; fig 1c
Abcam Mcam antibody (Abcam, ab24577) was used in immunohistochemistry on human samples (fig 1c) and in immunohistochemistry on mouse samples (fig 1c). Nat Commun (2018) ncbi
domestic rabbit monoclonal (EPR3208)
  • western blot; mouse; loading ...; fig 5b
In order to describe the effects of a polyphenol-rich strawberry extract on breast cancer cells, Abcam Mcam antibody (Abcam, ab75769) was used in western blot on mouse samples (fig 5b). Sci Rep (2016) ncbi
mouse monoclonal (P1H12)
  • flow cytometry; human; fig s4
Abcam Mcam antibody (Abcam, ab24577) was used in flow cytometry on human samples (fig s4). Stem Cell Reports (2015) ncbi
mouse monoclonal (P1H12)
  • western blot; human
Abcam Mcam antibody (Abcam, ab24577) was used in western blot on human samples . Cell Signal (2015) ncbi
mouse monoclonal (P1H12)
  • other; human; fig 2
In order to characterize capabilities and potentials of extracellular vesicle (EV) array, Abcam Mcam antibody (Abcam, ab24577) was used in other on human samples (fig 2). J Extracell Vesicles (2015) ncbi
Invitrogen
mouse monoclonal (P1H12)
  • immunocytochemistry; mouse; loading ...; fig 5s2c
Invitrogen Mcam antibody (Thermofisher, P1H12) was used in immunocytochemistry on mouse samples (fig 5s2c). elife (2021) ncbi
mouse monoclonal (P1H12)
  • flow cytometry; mouse; loading ...; fig s1a
Invitrogen Mcam antibody (eBiosciences, P1H12) was used in flow cytometry on mouse samples (fig s1a). EBioMedicine (2018) ncbi
mouse monoclonal (P1H12)
  • flow cytometry; cat; 1:25; tbl 3
Invitrogen Mcam antibody (eBioscience, 14-1469) was used in flow cytometry on cat samples at 1:25 (tbl 3). Cell Reprogram (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (P1H12)
  • flow cytometry; human; fig 4
  • western blot; human; fig 1
Santa Cruz Biotechnology Mcam antibody (Santa Cruz, sc-18837) was used in flow cytometry on human samples (fig 4) and in western blot on human samples (fig 1). Sci Rep (2016) ncbi
mouse monoclonal (A-9)
  • immunohistochemistry - paraffin section; human; loading ...; fig 3a
In order to find predictive markers for patients that will develop gastrointestinal graft-versus-host-disease, Santa Cruz Biotechnology Mcam antibody (SantaCruz, sc-374556) was used in immunohistochemistry - paraffin section on human samples (fig 3a). JCI Insight (2016) ncbi
mouse monoclonal (P1H12)
  • immunocytochemistry; human; 1:200; fig 4
Santa Cruz Biotechnology Mcam antibody (Santa Cruz, sc-18837) was used in immunocytochemistry on human samples at 1:200 (fig 4). Nat Commun (2016) ncbi
mouse monoclonal (P1H12)
  • flow cytometry; human
In order to identify the cell surface markers in synovial mesenchymal stem cells, Santa Cruz Biotechnology Mcam antibody (Santa Cruz, sc-18837) was used in flow cytometry on human samples . Cytometry A (2015) ncbi
mouse monoclonal (P1H12)
  • western blot; mouse
Santa Cruz Biotechnology Mcam antibody (Santa Cruz, sc-18837) was used in western blot on mouse samples . J Biol Chem (2015) ncbi
BD Biosciences
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; 1:100; loading ...
BD Biosciences Mcam antibody (BD Pharmingen, ME-9F1) was used in flow cytometry on mouse samples at 1:100. Sci Transl Med (2021) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; 1:100; loading ...
BD Biosciences Mcam antibody (BD Pharmingen, ME-9F1) was used in flow cytometry on mouse samples at 1:100. BMC Neurol (2021) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; mouse; fig s2b
  • immunocytochemistry; mouse; 5,000 ug/ml; fig st1
In order to discuss the cellular origins of fibroadipocytes in arrhythmogenic cardiomyopathy, BD Biosciences Mcam antibody (BD Pharmingen, 562229) was used in flow cytometry on mouse samples (fig s2b) and in immunocytochemistry on mouse samples at 5,000 ug/ml (fig st1). Circ Res (2016) ncbi
rat monoclonal (ME-9F1)
  • flow cytometry; human
In order to assess using adipose-tissue-derived mesenchymal stem cells for the treatment of glioblastoma in mice, BD Biosciences Mcam antibody (BD Biosciences, 562196) was used in flow cytometry on human samples . PLoS ONE (2015) ncbi
Articles Reviewed
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  2. Chandrakanthan V, Rorimpandey P, Zanini F, Chacon D, Olivier J, Joshi S, et al. Mesoderm-derived PDGFRA+ cells regulate the emergence of hematopoietic stem cells in the dorsal aorta. Nat Cell Biol. 2022;24:1211-1225 pubmed publisher
  3. Jin R, Gao Q, Yin C, Zou M, Lu K, Liu W, et al. The CD146-HIF-1α axis regulates epithelial cell migration and alveolar maturation in a mouse model of bronchopulmonary dysplasia. Lab Invest. 2022;102:794-804 pubmed publisher
  4. Duan J, Zhou Z, Ruan B, Fang Z, Ding J, Liu J, et al. Notch-Regulated c-Kit-Positive Liver Sinusoidal Endothelial Cells Contribute to Liver Zonation and Regeneration. Cell Mol Gastroenterol Hepatol. 2022;13:1741-1756 pubmed publisher
  5. Marr N, Meeson R, Kelly E, Fang Y, Peffers M, Pitsillides A, et al. CD146 Delineates an Interfascicular Cell Sub-Population in Tendon That Is Recruited during Injury through Its Ligand Laminin-α4. Int J Mol Sci. 2021;22: pubmed publisher
  6. Hayakawa M, Sakata A, Hayakawa H, Matsumoto H, Hiramoto T, Kashiwakura Y, et al. Characterization and visualization of murine coagulation factor VIII-producing cells in vivo. Sci Rep. 2021;11:14824 pubmed publisher
  7. Grol M, Haelterman N, Lim J, Munivez E, Archer M, Hudson D, et al. Tendon and motor phenotypes in the Crtap-/- mouse model of recessive osteogenesis imperfecta. elife. 2021;10: pubmed publisher
  8. Wang Y, Yang Y, Wang M, Wang S, Jeong J, Xu L, et al. Eosinophils attenuate hepatic ischemia-reperfusion injury in mice through ST2-dependent IL-13 production. Sci Transl Med. 2021;13: pubmed publisher
  9. Kishk N, Abdelfattah W, Shalaby N, Shehata H, Hassan A, Hegazy M, et al. The aquaporin4-IgG status and how it affects the clinical features and treatment response in NMOSD patients in Egypt. BMC Neurol. 2021;21:53 pubmed publisher
  10. Yang J, Kitami M, Pan H, Nakamura M, Zhang H, Liu F, et al. Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation. Sci Signal. 2021;14: pubmed publisher
  11. Ghoroghi S, Mary B, Larnicol A, Asokan N, Klein A, Osmani N, et al. Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes. elife. 2021;10: pubmed publisher
  12. Xu J, Wang Y, Hsu C, Negri S, Tower R, Gao Y, et al. Lysosomal protein surface expression discriminates fat- from bone-forming human mesenchymal precursor cells. elife. 2020;9: pubmed publisher
  13. Sun Z, Ji N, Ma Q, Zhu R, Chen Z, Wang Z, et al. Epithelial-Mesenchymal Transition in Asthma Airway Remodeling Is Regulated by the IL-33/CD146 Axis. Front Immunol. 2020;11:1598 pubmed publisher
  14. Evdokiou A, Kanisicak O, Gierek S, BARRY A, Ivey M, Zhang X, et al. Characterization of Burn Eschar Pericytes. J Clin Med. 2020;9: pubmed publisher
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  16. Breuer J, Korpos E, Hannocks M, Schneider Hohendorf T, Song J, Zondler L, et al. Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus. J Neuroinflammation. 2018;15:236 pubmed publisher
  17. Yang R, Yu T, Kou X, Gao X, Chen C, Liu D, et al. Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter. Nat Commun. 2018;9:2143 pubmed publisher
  18. Chen Y, Qin X, An Q, Yi J, Feng F, Yin D, et al. Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes. EBioMedicine. 2018;32:31-42 pubmed publisher
  19. Thomson C, van de Pavert S, Stakenborg M, Labeeuw E, Matteoli G, Mowat A, et al. Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators. J Immunol. 2018;201:215-229 pubmed publisher
  20. Kumar B, Garcia M, Weng L, Jung X, Murakami J, Hu X, et al. Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion. Leukemia. 2018;32:575-587 pubmed publisher
  21. Kammertoens T, Friese C, Arina A, Idel C, Briesemeister D, Rothe M, et al. Tumour ischaemia by interferon-? resembles physiological blood vessel regression. Nature. 2017;545:98-102 pubmed publisher
  22. Reynolds L, D Amico G, Lechertier T, Papachristodoulou A, Muñoz Félix J, De Arcangelis A, et al. Dual role of pericyte ?6?1-integrin in tumour blood vessels. J Cell Sci. 2017;130:1583-1595 pubmed publisher
  23. Guimarães Camboa N, Cattaneo P, Sun Y, Moore Morris T, Gu Y, Dalton N, et al. Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo. Cell Stem Cell. 2017;20:345-359.e5 pubmed publisher
  24. Luo Y, Duan H, Qian Y, Feng L, Wu Z, Wang F, et al. Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis. Cell Res. 2017;27:352-372 pubmed publisher
  25. Hu X, García M, Weng L, Jung X, Murakami J, Kumar B, et al. Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche. Nat Commun. 2016;7:13095 pubmed publisher
  26. Greco S, Torres Hernandez A, Kalabin A, Whiteman C, Rokosh R, Ravirala S, et al. Mincle Signaling Promotes Con A Hepatitis. J Immunol. 2016;197:2816-27 pubmed publisher
  27. Amatori S, Mazzoni L, Alvarez Suarez J, Giampieri F, Gasparrini M, Forbes Hernández T, et al. Polyphenol-rich strawberry extract (PRSE) shows in vitro and in vivo biological activity against invasive breast cancer cells. Sci Rep. 2016;6:30917 pubmed publisher
  28. Kurg R, Reinsalu O, Jagur S, Ounap K, Võsa L, Kasvandik S, et al. Biochemical and proteomic characterization of retrovirus Gag based microparticles carrying melanoma antigens. Sci Rep. 2016;6:29425 pubmed publisher
  29. Li W, Liu L, Gomez A, Zhang J, Ramadan A, Zhang Q, et al. Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease. JCI Insight. 2016;1: pubmed publisher
  30. Patenaude J, Perreault C. Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile. J Immunol. 2016;196:4760-70 pubmed publisher
  31. Lombardi R, Chen S, Ruggiero A, Gurha P, Czernuszewicz G, Willerson J, et al. Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene. Circ Res. 2016;119:41-54 pubmed publisher
  32. Guye P, Ebrahimkhani M, Kipniss N, Velazquez J, Schoenfeld E, Kiani S, et al. Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6. Nat Commun. 2016;7:10243 pubmed publisher
  33. Tsukui T, Ueha S, Shichino S, Inagaki Y, Matsushima K. Intratracheal cell transfer demonstrates the profibrotic potential of resident fibroblasts in pulmonary fibrosis. Am J Pathol. 2015;185:2939-48 pubmed publisher
  34. Denkovskij J, Rudys R, Bernotiene E, Minderis M, Bagdonas S, Kirdaite G. Cell surface markers and exogenously induced PpIX in synovial mesenchymal stem cells. Cytometry A. 2015;87:1001-11 pubmed publisher
  35. Gómez M, Qin Q, Biancardi M, Galiguis J, Dumas C, MacLean R, et al. Characterization and Multilineage Differentiation of Domestic and Black-Footed Cat Mesenchymal Stromal/Stem Cells from Abdominal and Subcutaneous Adipose Tissue. Cell Reprogram. 2015;17:376-92 pubmed publisher
  36. James S, Fox J, Afsari F, Lee J, Clough S, Knight C, et al. Multiparameter Analysis of Human Bone Marrow Stromal Cells Identifies Distinct Immunomodulatory and Differentiation-Competent Subtypes. Stem Cell Reports. 2015;4:1004-15 pubmed publisher
  37. de Melo S, Bittencourt S, Ferrazoli E, da Silva C, da Cunha F, da Silva F, et al. The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-Driven Brain Tumor. PLoS ONE. 2015;10:e0128922 pubmed publisher
  38. Tang X, Chen X, Xu Y, Qiao Y, Zhang X, Wang Y, et al. CD166 positively regulates MCAM via inhibition to ubiquitin E3 ligases Smurf1 and βTrCP through PI3K/AKT and c-Raf/MEK/ERK signaling in Bel-7402 hepatocellular carcinoma cells. Cell Signal. 2015;27:1694-702 pubmed publisher
  39. Wang W, Runkle K, Terkowski S, Ekaireb R, Witze E. Protein Depalmitoylation Is Induced by Wnt5a and Promotes Polarized Cell Behavior. J Biol Chem. 2015;290:15707-16 pubmed publisher
  40. Jørgensen M, Bæk R, Varming K. Potentials and capabilities of the Extracellular Vesicle (EV) Array. J Extracell Vesicles. 2015;4:26048 pubmed publisher