This is a Validated Antibody Database (VAD) review about mouse Mbnl1, based on 4 published articles (read how Labome selects the articles), using Mbnl1 antibody in all methods. It is aimed to help Labome visitors find the most suited Mbnl1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Mbnl1 synonym: Mbnl; mKIAA0428; muscleblind-like protein 1; muscleblind-like 1; triplet-expansion RNA-binding protein

Abcam
rabbit monoclonal (EPR4565)
  • immunohistochemistry - paraffin section; human; 1:500; fig 8
In order to study recapitulation of SCA7 pathology and promotion of accumulation of the FUS/TLS and MBNL1 RNA-binding proteins by lentiviral vector-mediated overexpression of mutant ataxin-7, Abcam Mbnl1 antibody (Abcam, ab108519) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 8). Mol Neurodegener (2016) ncbi
rabbit monoclonal (EPR4565)
  • western blot; mouse; 1:1000; fig 4
Abcam Mbnl1 antibody (Abcam, ab108519) was used in western blot on mouse samples at 1:1000 (fig 4). Int J Mol Sci (2016) ncbi
rabbit monoclonal (EPR4565)
  • western blot; human; 1:1000
Abcam Mbnl1 antibody (Abcam, ab108519) was used in western blot on human samples at 1:1000. Am J Pathol (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (3A4)
  • immunohistochemistry - frozen section; mouse; 1:500; fig 7
  • western blot; mouse; 1:1000; fig 7
  • immunohistochemistry - paraffin section; human; 1:500; fig 8
In order to study recapitulation of SCA7 pathology and promotion of accumulation of the FUS/TLS and MBNL1 RNA-binding proteins by lentiviral vector-mediated overexpression of mutant ataxin-7, Santa Cruz Biotechnology Mbnl1 antibody (Santa Cruz, sc-47740) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 7), in western blot on mouse samples at 1:1000 (fig 7) and in immunohistochemistry - paraffin section on human samples at 1:500 (fig 8). Mol Neurodegener (2016) ncbi
mouse monoclonal (3A4)
  • immunocytochemistry; human; 1:100; fig 4
Santa Cruz Biotechnology Mbnl1 antibody (Santa Cruz, sc-47740) was used in immunocytochemistry on human samples at 1:100 (fig 4). J Biol Chem (2015) ncbi
Articles Reviewed
  1. Alves S, Marais T, Biferi M, Furling D, Marinello M, El Hachimi K, et al. Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins. Mol Neurodegener. 2016;11:58 pubmed publisher
  2. Zhang B, Cai H, Wei X, Sun J, Lan X, Lei C, et al. miR-30-5p Regulates Muscle Differentiation and Alternative Splicing of Muscle-Related Genes by Targeting MBNL. Int J Mol Sci. 2016;17: pubmed publisher
  3. Du J, Aleff R, Soragni E, Kalari K, Nie J, Tang X, et al. RNA toxicity and missplicing in the common eye disease fuchs endothelial corneal dystrophy. J Biol Chem. 2015;290:5979-90 pubmed publisher
  4. Screen M, Jonson P, Raheem O, Palmio J, Laaksonen R, Lehtimaki T, et al. Abnormal splicing of NEDD4 in myotonic dystrophy type 2: possible link to statin adverse reactions. Am J Pathol. 2014;184:2322-32 pubmed publisher