This is a Validated Antibody Database (VAD) review about mouse Lig1, based on 5 published articles (read how Labome selects the articles), using Lig1 antibody in all methods. It is aimed to help Labome visitors find the most suited Lig1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Lig1 synonym: AL033288; LigI; DNA ligase 1; DNA ligase I; polydeoxyribonucleotide synthase [ATP] 1

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (C-5)
  • western blot knockout validation; human; fig 4a
Santa Cruz Biotechnology Lig1 antibody (Santa Cruz, sc-271678) was used in western blot knockout validation on human samples (fig 4a). PLoS Pathog (2017) ncbi
Proteintech Group
rabbit polyclonal
  • western blot knockout validation; mouse; fig s2
Proteintech Group Lig1 antibody (Proteintech, 18051-1-AP) was used in western blot knockout validation on mouse samples (fig s2). Proc Natl Acad Sci U S A (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-5)
  • western blot knockout validation; human; fig 4a
Santa Cruz Biotechnology Lig1 antibody (Santa Cruz, sc-271678) was used in western blot knockout validation on human samples (fig 4a). PLoS Pathog (2017) ncbi
mouse monoclonal (1A9)
  • western blot; human; loading ...; fig 1b
Santa Cruz Biotechnology Lig1 antibody (Santa Cruz, sc-47703) was used in western blot on human samples (fig 1b). Mol Cell (2017) ncbi
Proteintech Group
rabbit polyclonal
  • western blot knockout validation; mouse; fig s2
Proteintech Group Lig1 antibody (Proteintech, 18051-1-AP) was used in western blot knockout validation on mouse samples (fig s2). Proc Natl Acad Sci U S A (2016) ncbi
rabbit polyclonal
  • western blot; human
Proteintech Group Lig1 antibody (Proteintech Group, 18051-1-AP) was used in western blot on human samples . Cell Rep (2014) ncbi
GeneTex
mouse monoclonal (10H5)
  • western blot; human; fig s2
In order to study the functional significance of the DNA polymerase-beta interaction with BRCA1, GeneTex Lig1 antibody (GeneTex Inc, GTX70141) was used in western blot on human samples (fig s2). PLoS ONE (2013) ncbi
Articles Reviewed
  1. Long Q, Yan R, Hu J, Cai D, Mitra B, Kim E, et al. The role of host DNA ligases in hepadnavirus covalently closed circular DNA formation. PLoS Pathog. 2017;13:e1006784 pubmed publisher
  2. Biehs R, Steinlage M, Barton O, Juhasz S, Künzel J, Spies J, et al. DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination. Mol Cell. 2017;65:671-684.e5 pubmed publisher
  3. Lu G, Duan J, Shu S, Wang X, Gao L, Guo J, et al. Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining. Proc Natl Acad Sci U S A. 2016;113:1256-60 pubmed publisher
  4. Han L, Masani S, Hsieh C, Yu K. DNA ligase I is not essential for mammalian cell viability. Cell Rep. 2014;7:316-20 pubmed publisher
  5. Masaoka A, Gassman N, Horton J, Kedar P, Witt K, Hobbs C, et al. Interaction between DNA Polymerase ? and BRCA1. PLoS ONE. 2013;8:e66801 pubmed publisher