This is a Validated Antibody Database (VAD) review about mouse Lgr5, based on 12 published articles (read how Labome selects the articles), using Lgr5 antibody in all methods. It is aimed to help Labome visitors find the most suited Lgr5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Lgr5 synonym: FEX; Gpr49

Abcam
domestic rabbit monoclonal (EPR3065Y)
  • immunohistochemistry; mouse; loading ...; fig 1e
  • western blot; mouse; 1:1000; loading ...; fig 1c
Abcam Lgr5 antibody (Abcam, AB75850) was used in immunohistochemistry on mouse samples (fig 1e) and in western blot on mouse samples at 1:1000 (fig 1c). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (EPR3065Y)
  • immunohistochemistry - paraffin section; human; loading ...; fig 3a
  • immunocytochemistry; human; loading ...; fig 3b
  • western blot; human; loading ...; fig 4a, s2a
Abcam Lgr5 antibody (Abcam, ab199335) was used in immunohistochemistry - paraffin section on human samples (fig 3a), in immunocytochemistry on human samples (fig 3b) and in western blot on human samples (fig 4a, s2a). BMC Cancer (2019) ncbi
domestic rabbit monoclonal (EPR3065Y)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1a
Abcam Lgr5 antibody (Abcam, ab75850) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1a). Gastric Cancer (2018) ncbi
domestic rabbit monoclonal (EPR3065Y)
  • flow cytometry; mouse; loading ...; fig st2
In order to identify a role for Sca-1 in mouse gastric cancer, Abcam Lgr5 antibody (Abcam, ab75850) was used in flow cytometry on mouse samples (fig st2). Stem Cells (2016) ncbi
domestic rabbit monoclonal (EPR3065Y)
  • immunohistochemistry - paraffin section; human; fig s12
  • immunohistochemistry - paraffin section; mouse; fig 1
  • western blot; mouse; fig 3
Abcam Lgr5 antibody (Abcam, EPR3065Y) was used in immunohistochemistry - paraffin section on human samples (fig s12), in immunohistochemistry - paraffin section on mouse samples (fig 1) and in western blot on mouse samples (fig 3). Sci Rep (2015) ncbi
domestic rabbit monoclonal (EPR3065Y)
  • western blot; human; loading ...; fig 2c
Abcam Lgr5 antibody (Abcam, ab75850) was used in western blot on human samples (fig 2c). Br J Cancer (2015) ncbi
domestic rabbit monoclonal (EPR3065Y)
  • immunohistochemistry - paraffin section; rat; 1:250
Abcam Lgr5 antibody (Abcam, ab75850) was used in immunohistochemistry - paraffin section on rat samples at 1:250. BMC Cancer (2013) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3c
Invitrogen Lgr5 antibody (Thermo Fisher Scientific, PA5-49691) was used in western blot on mouse samples at 1:1000 (fig 3c). JCI Insight (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3a
Invitrogen Lgr5 antibody (ThermoFisher Scientific, PA5-49691) was used in western blot on human samples (fig 3a). Mol Cancer (2020) ncbi
Miltenyi Biotec
rat monoclonal (DA04-10E8.9)
  • flow cytometry; human; 1:50; loading ...; fig 1b
Miltenyi Biotec Lgr5 antibody (Miltenyi Biotech, 130-111-393) was used in flow cytometry on human samples at 1:50 (fig 1b). J Hematol Oncol (2019) ncbi
Novus Biologicals
domestic rabbit polyclonal (2G10)
Novus Biologicals Lgr5 antibody (novus Biologicals, NBP128904) was used . J Clin Endocrinol Metab (2015) ncbi
Abcepta
domestic rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 5a
Abcepta Lgr5 antibody (ABGENT, AP2745d) was used in western blot on human samples at 1:2000 (fig 5a). iScience (2022) ncbi
Articles Reviewed
  1. Pan R, Yu Y, Zhu H, Zhang W, Qin Y, Ye L, et al. RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation. iScience. 2022;25:105184 pubmed publisher
  2. Russo A, Colina J, Moy J, Baligod S, Czarnecki A, Varughese P, et al. Silencing PTEN in the fallopian tube promotes enrichment of cancer stem cell-like function through loss of PAX2. Cell Death Dis. 2021;12:375 pubmed publisher
  3. Li W, Zhang N, Jin C, Long M, Rajabi H, Yasumizu Y, et al. MUC1-C drives stemness in progression of colitis to colorectal cancer. JCI Insight. 2020;5: pubmed publisher
  4. Pothuraju R, Rachagani S, Krishn S, Chaudhary S, Nimmakayala R, Siddiqui J, et al. Molecular implications of MUC5AC-CD44 axis in colorectal cancer progression and chemoresistance. Mol Cancer. 2020;19:37 pubmed publisher
  5. Piao L, Yang Z, Feng Y, Zhang C, Cui C, Xuan Y. LETM1 is a potential biomarker of prognosis in lung non-small cell carcinoma. BMC Cancer. 2019;19:898 pubmed publisher
  6. Hwang W, Lan H, Cheng W, Huang S, Yang M. Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer. J Hematol Oncol. 2019;12:10 pubmed publisher
  7. Walker R, Poleszczuk J, Mejia J, Lee J, Pimiento J, Malafa M, et al. Toward early detection of Helicobacter pylori-associated gastric cancer. Gastric Cancer. 2018;21:196-203 pubmed publisher
  8. Park J, Park J, Park D, Kim D, Kim H. Stem Cells Antigen-1 Enriches for a Cancer Stem Cell-Like Subpopulation in Mouse Gastric Cancer. Stem Cells. 2016;34:1177-87 pubmed publisher
  9. Su X, Yan H, Huang Y, Yun H, Zeng B, Wang E, et al. Expression of FABP4, adipsin and adiponectin in Paneth cells is modulated by gut Lactobacillus. Sci Rep. 2015;5:18588 pubmed publisher
  10. Shaikh L, Zhou J, Teo A, Garg S, Neogi S, Figg N, et al. LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal. J Clin Endocrinol Metab. 2015;100:E836-44 pubmed publisher
  11. Morgan R, Molnár E, Jones R, Collard T, Lane J, Greenhough A, et al. Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells. Br J Cancer. 2015;112:714-9 pubmed publisher
  12. Femia A, Dolara P, Salvadori M, Caderni G. Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear ?-catenin. BMC Cancer. 2013;13:48 pubmed publisher