This is a Validated Antibody Database (VAD) review about mouse Lcp2, based on 6 published articles (read how Labome selects the articles), using Lcp2 antibody in all methods. It is aimed to help Labome visitors find the most suited Lcp2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Lcp2 synonym: AI323664; BB161688; SLP-76; SLP76; m1Khoe; twm; lymphocyte cytosolic protein 2; SH2 domain-containing leukocyte protein of 76 kDa; SLP-76 tyrosine phosphoprotein

Abcam
rabbit monoclonal (EP2853Y)
  • western blot; human; loading ...; fig s6b
In order to demonstrate that PD-1 inhibits T cell function primarily by inactivating CD28 signaling, Abcam Lcp2 antibody (Abcam, ab75829) was used in western blot on human samples (fig s6b). Science (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-7)
  • immunoprecipitation; human; fig 2
  • western blot; human; fig 2
Santa Cruz Biotechnology Lcp2 antibody (Santa Cruz, F-7) was used in immunoprecipitation on human samples (fig 2) and in western blot on human samples (fig 2). Cell Signal (2015) ncbi
Bio-Rad
mouse monoclonal (SLP-76/03)
  • western blot; human
Bio-Rad Lcp2 antibody (AbD Serotec, SLP76/03) was used in western blot on human samples . J Immunol (2013) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; loading ...; fig 5c
In order to explore signaling pathways regulated by RLTPR in T and B cells, Cell Signaling Technology Lcp2 antibody (Cell Signaling Technology, 4958) was used in western blot on human samples (fig 5c). J Exp Med (2016) ncbi
rabbit polyclonal
  • western blot; human
In order to study the molecular signaling responsible for retinoic acid-induced differentiation, Cell Signaling Technology Lcp2 antibody (Cell Signaling, 4958) was used in western blot on human samples . PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; tbl 4
Cell Signaling Technology Lcp2 antibody (Cell Signaling, 4958) was used in western blot on human samples at 1:1000 (tbl 4). Methods Mol Biol (2014) ncbi
Articles Reviewed
  1. Hui E, Cheung J, Zhu J, Su X, Taylor M, Wallweber H, et al. T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition. Science. 2017;355:1428-1433 pubmed publisher
  2. Roncagalli R, Cucchetti M, Jarmuzynski N, Gregoire C, Bergot E, Audebert S, et al. The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells. J Exp Med. 2016;213:2437-2457 pubmed
  3. Bunaciu R, Jensen H, Macdonald R, Latocha D, Varner J, Yen A. 6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells. PLoS ONE. 2015;10:e0135668 pubmed publisher
  4. Bilal M, Zhang E, Dinkel B, Hardy D, Yankee T, Houtman J. GADS is required for TCR-mediated calcium influx and cytokine release, but not cellular adhesion, in human T cells. Cell Signal. 2015;27:841-50 pubmed publisher
  5. Cox S. Intracellular signaling of CTLs. Methods Mol Biol. 2014;1186:49-63 pubmed publisher
  6. Paster W, Brockmeyer C, Fu G, Simister P, de Wet B, Martinez Riaño A, et al. GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development. J Immunol. 2013;190:3749-56 pubmed publisher