This is a Validated Antibody Database (VAD) review about mouse Lats1, based on 66 published articles (read how Labome selects the articles), using Lats1 antibody in all methods. It is aimed to help Labome visitors find the most suited Lats1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Lats1 synonym: AW208599

Santa Cruz Biotechnology
mouse monoclonal
  • western blot; human; 1:100; loading ...; fig 4c
Santa Cruz Biotechnology Lats1 antibody (Santa Cruz, sc-398560) was used in western blot on human samples at 1:100 (fig 4c). elife (2020) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3a
Invitrogen Lats1 antibody (Invitrogen, PA5-64591) was used in western blot on mouse samples at 1:1000 (fig 3a). J Clin Invest (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C66B5)
  • western blot; human; 1:1000; loading ...; fig 3h
Cell Signaling Technology Lats1 antibody (CST, 3477) was used in western blot on human samples at 1:1000 (fig 3h). Nat Commun (2022) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 3g
Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 8654) was used in western blot on human samples (fig 3g). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; loading ...; fig 3g
Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 3477) was used in western blot on human samples (fig 3g). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; loading ...
Cell Signaling Technology Lats1 antibody (Cell Signal, 3477) was used in western blot on human samples . Clin Transl Med (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s1b, s3a
Cell Signaling Technology Lats1 antibody (CST, 9157) was used in western blot on mouse samples at 1:1000 (fig s1b, s3a). Aging Cell (2021) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; 1:1000; loading ...; fig s1b, s3a
Cell Signaling Technology Lats1 antibody (CST, 3477) was used in western blot on mouse samples at 1:1000 (fig s1b, s3a). Aging Cell (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 11
Cell Signaling Technology Lats1 antibody (Cell Signaling Technologies, 9157) was used in western blot on human samples at 1:1000 (fig 11). PLoS Pathog (2021) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; loading ...; fig 7a
Cell Signaling Technology Lats1 antibody (CST, 3477 S) was used in western blot on mouse samples (fig 7a). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; 1:1000; loading ...; fig 4g
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on mouse samples at 1:1000 (fig 4g). Cell Death Dis (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4g
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on mouse samples at 1:1000 (fig 4g). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; 1:1000; loading ...; fig 3a
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on mouse samples at 1:1000 (fig 3a). J Clin Invest (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 4i
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on human samples at 1:1000 (fig 4i). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:1000; loading ...; fig 2h
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples at 1:1000 (fig 2h). PLoS Biol (2021) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; 1:1000; loading ...; fig 2h
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on human samples at 1:1000 (fig 2h). PLoS Biol (2021) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:1000; loading ...; fig 6a, 6b
Cell Signaling Technology Lats1 antibody (CST, 8654) was used in western blot on human samples at 1:1000 (fig 6a, 6b). Am J Transl Res (2021) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; 1:1000; loading ...; fig 6a, 6b
Cell Signaling Technology Lats1 antibody (CST, 3477) was used in western blot on human samples at 1:1000 (fig 6a, 6b). Am J Transl Res (2021) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; 1:1000; loading ...; fig 6e
Cell Signaling Technology Lats1 antibody (CST, 3477) was used in western blot on human samples at 1:1000 (fig 6e). Mol Oncol (2021) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:500; loading ...; fig 6a
Cell Signaling Technology Lats1 antibody (CST, 8654) was used in western blot on human samples at 1:500 (fig 6a). Mol Oncol (2021) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; 1:1000; loading ...; fig 5c
Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 3477S) was used in western blot on human samples at 1:1000 (fig 5c). Cell Rep (2020) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:1000; loading ...; fig 5c
Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 8654S) was used in western blot on human samples at 1:1000 (fig 5c). Cell Rep (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 4b
Cell Signaling Technology Lats1 antibody (CST, 9157S) was used in western blot on human samples at 1:1000 (fig 4b). Signal Transduct Target Ther (2020) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; loading ...; fig 4d
Cell Signaling Technology Lats1 antibody (CST, C66B5) was used in western blot on human samples (fig 4d). Theranostics (2020) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 1s2a
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 1s2a). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1s2a, 1s3a
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on human samples (fig 1s2a, 1s3a). elife (2020) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; mouse; 1:1000; loading ...; fig 7b
Cell Signaling Technology Lats1 antibody (CST, 8654) was used in western blot on mouse samples at 1:1000 (fig 7b). elife (2020) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology Lats1 antibody (Cell Signaling, C66B5) was used in western blot on mouse samples (fig 5a). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology Lats1 antibody (Cell Signaling, D57D3) was used in western blot on mouse samples (fig 5a). Nat Commun (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig s9a
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig s9a). Nat Commun (2020) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on human samples (fig 2b). Redox Biol (2020) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 2b). Redox Biol (2020) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 7c
Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 8654S) was used in western blot on human samples (fig 7c). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on human samples (fig 3b). Biomolecules (2019) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:1000; loading ...; fig 3b, 3j
Cell Signaling Technology Lats1 antibody (CST, 8654) was used in western blot on human samples at 1:1000 (fig 3b, 3j). elife (2019) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; 1:1000; loading ...; fig 3b, 3j
Cell Signaling Technology Lats1 antibody (CST, 3477) was used in western blot on human samples at 1:1000 (fig 3b, 3j). elife (2019) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:500; loading ...; fig 3a
Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 8654) was used in western blot on human samples at 1:500 (fig 3a). Cancer Manag Res (2019) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; fig 8a
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 8a). PLoS Biol (2019) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; loading ...; fig 1f
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on human samples (fig 1f). Curr Biol (2019) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; loading ...; fig 2b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on mouse samples (fig 2b). Oncogene (2019) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; 1:500; loading ...; fig 7a
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on human samples at 1:500 (fig 7a). Nat Commun (2018) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; loading ...; fig 1b
Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, C66B5) was used in western blot on mouse samples (fig 1b). Nature (2018) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:1000; loading ...; fig 7b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples at 1:1000 (fig 7b). J Cell Sci (2018) ncbi
domestic rabbit monoclonal (C66B5)
  • immunocytochemistry; human; 1:600; loading ...; fig 5b
  • western blot; human; 1:1000; loading ...; fig 5c
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in immunocytochemistry on human samples at 1:600 (fig 5b) and in western blot on human samples at 1:1000 (fig 5c). J Cell Sci (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5c
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on human samples at 1:1000 (fig 5c). J Cell Sci (2018) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; rat; 1:500; loading ...; fig 2a
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on rat samples at 1:500 (fig 2a). Mol Med Rep (2018) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; rat; 1:5000; loading ...; fig 7c
Cell Signaling Technology Lats1 antibody (Cell Signaling Technologies, 9157) was used in immunoprecipitation on rat samples at 1:5000 (fig 7c). J Cell Biol (2018) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; 1:500; fig 3b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477S) was used in western blot on human samples at 1:500 (fig 3b). Oncotarget (2017) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:500; fig 3b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654S) was used in western blot on human samples at 1:500 (fig 3b). Oncotarget (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1c
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on human samples (fig 1c). Mol Cell (2017) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 8c
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 8c). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; loading ...; fig 8c
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on human samples (fig 8c). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; 1:2000; loading ...; fig 1a
In order to assess structural and biochemical phenotypes of neuronal transcriptional repression-induced atypical cell death in patient brains with Huntington's disease, Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on mouse samples at 1:2000 (fig 1a). Acta Neuropathol Commun (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1b
  • western blot; mouse; 1:5000; loading ...; fig 1a
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 3a
In order to assess structural and biochemical phenotypes of neuronal transcriptional repression-induced atypical cell death in patient brains with Huntington's disease, Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1b), in western blot on mouse samples at 1:5000 (fig 1a) and in immunohistochemistry - paraffin section on human samples at 1:100 (fig 3a). Acta Neuropathol Commun (2017) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 2g
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 2g). EMBO Rep (2017) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; loading ...; fig 2g
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on human samples (fig 2g). EMBO Rep (2017) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; loading ...; fig 3d
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on human samples (fig 3d). Stem Cells Dev (2017) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; 1:1000; loading ...; fig 1b, 4d,ED1f
  • western blot; mouse; 1:1000
In order to define the interaction between LATS1/2 and the estrogen receptor signaling in breast cancer initiation., Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on human samples at 1:1000 (fig 1b, 4d,ED1f) and in western blot on mouse samples at 1:1000. Nature (2017) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig s4a
In order to report that DUB3 family deubiquitylating enzymes regulate Hippo pathway activity, Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig s4a). PLoS ONE (2017) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; mouse; 1:1000; loading ...; fig 3a
Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 8654) was used in western blot on mouse samples at 1:1000 (fig 3a). Nat Commun (2016) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; 1:1000; loading ...; fig 3a
Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 3477) was used in western blot on mouse samples at 1:1000 (fig 3a). Nat Commun (2016) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; fig 1a
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on mouse samples (fig 1a). Cell (2016) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; loading ...; fig 4
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on human samples (fig 4). Mol Clin Oncol (2016) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; mouse; fig 1
  • western blot; human; fig 6
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on mouse samples (fig 1) and in western blot on human samples (fig 6). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; fig 6
  • western blot; mouse; fig 1
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on human samples (fig 6) and in western blot on mouse samples (fig 1). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig s2f
In order to demonstrate that the Hippo, Wnt/beta-catenin, and Notch pathways interact to regulate liver size and inhibit hepatocellular carcinoma, Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig s2f). J Clin Invest (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s5
Cell Signaling Technology Lats1 antibody (cell signalling, 9157) was used in western blot on human samples (fig s5). J Clin Invest (2016) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; 1:200; fig 4
  • western blot; human; 1:200; fig 4
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on mouse samples at 1:200 (fig 4) and in western blot on human samples at 1:200 (fig 4). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; fig s3
In order to investigate the roles of NF2, LATS1/2, and YAP in the branching morphogenesis of the mouse kidney, Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on mouse samples at 1:500 (fig s3). Nat Commun (2016) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; 1:1000; fig s3
In order to investigate the roles of NF2, LATS1/2, and YAP in the branching morphogenesis of the mouse kidney, Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on mouse samples at 1:1000 (fig s3). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 4a
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 4a) and in western blot on mouse samples (fig 4b). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; loading ...; fig 4b
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on mouse samples (fig 4b) and in western blot on human samples (fig 4a). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 4b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 4b). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology Lats1 antibody (Cell signaling, 9157) was used in western blot on human samples (fig 5). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; fig 2f
In order to study GSK3 inhibitor BIS I, YAP-dependent EMT signature in PDAC cell lines, and SMADs expression level, Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on human samples (fig 2f). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 2f
In order to study GSK3 inhibitor BIS I, YAP-dependent EMT signature in PDAC cell lines, and SMADs expression level, Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on human samples (fig 2f). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
  • western blot; mouse; fig 5
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on human samples (fig 4) and in western blot on mouse samples (fig 5). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; fig 5
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 5). Oncotarget (2016) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; fig 5
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on human samples (fig 5). Oncotarget (2016) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; fig 4
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on mouse samples (fig 4). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
In order to study the activation mechanisms of core Hippo pathway components, Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 9157) was used in western blot on human samples (fig 4). EMBO Rep (2016) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; 1:2000; fig 1
Cell Signaling Technology Lats1 antibody (Cell signaling, 3477) was used in western blot on human samples at 1:2000 (fig 1). Nat Commun (2015) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology Lats1 antibody (Cell signaling, 8654) was used in western blot on human samples at 1:1000 (fig 4). Nat Commun (2015) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; 1:1000; fig 5
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on mouse samples at 1:1000 (fig 5). Nat Cell Biol (2015) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; 1:1000; fig 1
Cell Signaling Technology Lats1 antibody (Cell Signaling, 3477) was used in western blot on human samples at 1:1000 (fig 1). Nat Cell Biol (2015) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:500
In order to study CDC26 phosphorylation and its effect on the tetratricopeptide repeat subcomplex of APC/C, Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 8654) was used in western blot on human samples at 1:500. PLoS ONE (2015) ncbi
domestic rabbit monoclonal (C66B5)
  • immunoprecipitation; mouse; 1:300-1:600; fig 5
Cell Signaling Technology Lats1 antibody (Cell Signaling, C66B5) was used in immunoprecipitation on mouse samples at 1:300-1:600 (fig 5). Nat Cell Biol (2015) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; mouse; fig 6j
  • western blot; human; fig 6i
Cell Signaling Technology Lats1 antibody (Cell signaling, 8654) was used in western blot on mouse samples (fig 6j) and in western blot on human samples (fig 6i). Dev Cell (2014) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; mouse; fig 8
In order to investigate if and how mTOR regulates YAP, Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 3477) was used in western blot on mouse samples (fig 8). J Exp Med (2014) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human
In order to investigate the expression and activity of receptor tyrosine kinases, MAP kinase, AKT, or Hippo pathways in human schwannomas, Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 3477) was used in western blot on human samples . Neuro Oncol (2014) ncbi
domestic rabbit monoclonal (C66B5)
  • western blot; human; 1:1000; fig 1
Cell Signaling Technology Lats1 antibody (CST, 3477S) was used in western blot on human samples at 1:1000 (fig 1). Nat Cell Biol (2012) ncbi
Articles Reviewed
  1. Yu B, Su J, Shi Q, Liu Q, Ma J, Ru G, et al. KMT5A-methylated SNIP1 promotes triple-negative breast cancer metastasis by activating YAP signaling. Nat Commun. 2022;13:2192 pubmed publisher
  2. Zhang S, Liang S, Wu D, Guo H, Ma K, Liu L. LncRNA coordinates Hippo and mTORC1 pathway activation in cancer. Cell Death Dis. 2021;12:822 pubmed publisher
  3. Zhang Y, He L, Huang L, Yao S, Lin N, Li P, et al. Oncogenic PAX6 elicits CDK4/6 inhibitor resistance by epigenetically inactivating the LATS2-Hippo signaling pathway. Clin Transl Med. 2021;11:e503 pubmed publisher
  4. Xu X, Shen X, Wang J, Feng W, Wang M, Miao X, et al. YAP prevents premature senescence of astrocytes and cognitive decline of Alzheimer's disease through regulating CDK6 signaling. Aging Cell. 2021;20:e13465 pubmed publisher
  5. Van Sciver N, Ohashi M, Pauly N, Bristol J, Nelson S, JOHANNSEN E, et al. Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells. PLoS Pathog. 2021;17:e1009783 pubmed publisher
  6. Zheng Z, Li C, Shao G, Li J, Xu K, Zhao Z, et al. Hippo-YAP/MCP-1 mediated tubular maladaptive repair promote inflammation in renal failed recovery after ischemic AKI. Cell Death Dis. 2021;12:754 pubmed publisher
  7. Chi X, Luo W, Song J, Li B, Su T, Yu M, et al. Kindlin-2 in Sertoli cells is essential for testis development and male fertility in mice. Cell Death Dis. 2021;12:604 pubmed publisher
  8. Tamura T, Kodama T, Sato K, Murai K, Yoshioka T, Shigekawa M, et al. Dysregulation of PI3K and Hippo signaling pathways synergistically induces chronic pancreatitis via CTGF upregulation. J Clin Invest. 2021;131: pubmed publisher
  9. Dai M, Yan G, Wang N, Daliah G, Edick A, Poulet S, et al. In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy. Nat Commun. 2021;12:3055 pubmed publisher
  10. Zhou R, Wu Q, Wang M, Irani S, Li X, Zhang Q, et al. The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration. PLoS Biol. 2021;19:e3001122 pubmed publisher
  11. Hu Z, Chen Y, Huang M, Tu J, Tu S, Pan Y, et al. PLG inhibits Hippo signaling pathway through SRC in the hepatitis B virus-induced hepatocellular-carcinoma progression. Am J Transl Res. 2021;13:515-531 pubmed
  12. Shields C, Potlapalli S, Cuya Smith S, Chappell S, Chen D, Martinez D, et al. Epigenetic regulator BMI1 promotes alveolar rhabdomyosarcoma proliferation and constitutes a novel therapeutic target. Mol Oncol. 2021;: pubmed publisher
  13. Hao Q, Zong X, Sun Q, Lin Y, Song Y, Hashemikhabir S, et al. The S-phase-induced lncRNA SUNO1 promotes cell proliferation by controlling YAP1/Hippo signaling pathway. elife. 2020;9: pubmed publisher
  14. Seo G, Han H, Vargas R, Yang B, Li X, Wang W. MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation. Cell Rep. 2020;32:107860 pubmed publisher
  15. Wen X, Wan J, He Q, Wang M, Li S, Jiang M, et al. p190A inactivating mutations cause aberrant RhoA activation and promote malignant transformation via the Hippo-YAP pathway in endometrial cancer. Signal Transduct Target Ther. 2020;5:81 pubmed publisher
  16. Guo Q, Quan M, Dong J, Bai J, Wang J, Han R, et al. The WW domains dictate isoform-specific regulation of YAP1 stability and pancreatic cancer cell malignancy. Theranostics. 2020;10:4422-4436 pubmed publisher
  17. Bae S, Ni L, Luo X. STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism. elife. 2020;9: pubmed publisher
  18. Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, et al. Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin. elife. 2020;9: pubmed publisher
  19. Choi S, Bae H, Jeong S, Park I, Cho H, Hong S, et al. YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells. Nat Commun. 2020;11:519 pubmed publisher
  20. Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, et al. YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology. Nat Commun. 2020;11:507 pubmed publisher
  21. Escoll M, Lastra D, Pajares M, Robledinos Antón N, Rojo A, Fernández Ginés R, et al. Transcription factor NRF2 uses the Hippo pathway effector TAZ to induce tumorigenesis in glioblastomas. Redox Biol. 2020;30:101425 pubmed publisher
  22. Kim J, Berrios C, Kim M, SCHADE A, Adelmant G, Yeerna H, et al. STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells. elife. 2020;9: pubmed publisher
  23. Zhou L, Wang Q, Zhang H, Li Y, Xie S, Xu M. YAP Inhibition by Nuciferine via AMPK-Mediated Downregulation of HMGCR Sensitizes Pancreatic Cancer Cells to Gemcitabine. Biomolecules. 2019;9: pubmed publisher
  24. Park M, Kim A, Manandhar S, Oh S, Jang G, Kang L, et al. CCN1 interlinks integrin and hippo pathway to autoregulate tip cell activity. elife. 2019;8: pubmed publisher
  25. Rong X, Han Q, Lin X, Kremerskothen J, Wang E. FRMPD1 activates the Hippo pathway via interaction with WWC3 to suppress the proliferation and invasiveness of lung cancer cells. Cancer Manag Res. 2019;11:3395-3410 pubmed publisher
  26. Miller C, Lou H, Simpson C, van de Kooij B, Ha B, Fisher O, et al. Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output. PLoS Biol. 2019;17:e2006540 pubmed publisher
  27. Rausch V, Bostrom J, Park J, Bravo I, Feng Y, Hay D, et al. The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae. Curr Biol. 2019;29:242-255.e6 pubmed publisher
  28. Pan W, Moroishi T, Koo J, Guan K. Cell type-dependent function of LATS1/2 in cancer cell growth. Oncogene. 2019;38:2595-2610 pubmed publisher
  29. Yao F, Zhou Z, Kim J, Hang Q, Xiao Z, Ton B, et al. SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity. Nat Commun. 2018;9:2269 pubmed publisher
  30. Du X, Wen J, Wang Y, Karmaus P, Khatamian A, Tan H, et al. Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells. Nature. 2018;558:141-145 pubmed publisher
  31. Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci. 2018;131: pubmed publisher
  32. Chen B, Liu G. WWC3 inhibits intimal proliferation following vascular injury via the Hippo signaling pathway. Mol Med Rep. 2018;17:5175-5183 pubmed publisher
  33. Wigerius M, Quinn D, Diab A, Clattenburg L, Kolar A, Qi J, et al. The polarity protein Angiomotin p130 controls dendritic spine maturation. J Cell Biol. 2018;217:715-730 pubmed publisher
  34. Zheng X, Dong Q, Zhang X, Han Q, Han X, Han Y, et al. The coiled-coil domain of oncogene RASSF 7 inhibits hippo signaling and promotes non-small cell lung cancer. Oncotarget. 2017;8:78734-78748 pubmed publisher
  35. Peng C, Zhu Y, Zhang W, Liao Q, Chen Y, Zhao X, et al. Regulation of the Hippo-YAP Pathway by Glucose Sensor O-GlcNAcylation. Mol Cell. 2017;68:591-604.e5 pubmed publisher
  36. Kim J, Kim Y, Kim J, Park D, Bae H, Lee D, et al. YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation. J Clin Invest. 2017;127:3441-3461 pubmed publisher
  37. Yamanishi E, Hasegawa K, Fujita K, Ichinose S, Yagishita S, Murata M, et al. A novel form of necrosis, TRIAD, occurs in human Huntington's disease. Acta Neuropathol Commun. 2017;5:19 pubmed publisher
  38. Heidary Arash E, Shiban A, Song S, Attisano L. MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells. EMBO Rep. 2017;18:420-436 pubmed publisher
  39. Chorzalska A, Kim J, Roder K, Tepper A, Ahsan N, Rao R, et al. Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia. Stem Cells Dev. 2017;26:656-677 pubmed publisher
  40. Britschgi A, Duss S, Kim S, Couto J, Brinkhaus H, Koren S, et al. The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα. Nature. 2017;541:541-545 pubmed publisher
  41. Nguyen H, Kugler J, Cohen S. DUB3 Deubiquitylating Enzymes Regulate Hippo Pathway Activity by Regulating the Stability of ITCH, LATS and AMOT Proteins. PLoS ONE. 2017;12:e0169587 pubmed publisher
  42. Jerić I, Maurer G, Cavallo A, Raguz J, Desideri E, Tarkowski B, et al. A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis. Nat Commun. 2016;7:13781 pubmed publisher
  43. Moroishi T, Hayashi T, Pan W, Fujita Y, Holt M, Qin J, et al. The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity. Cell. 2016;167:1525-1539.e17 pubmed publisher
  44. Galoian K, Luo S, Qureshi A, Patel P, Price R, Morse A, et al. Effect of cytostatic proline rich polypeptide-1 on tumor suppressors of inflammation pathway signaling in chondrosarcoma. Mol Clin Oncol. 2016;5:618-624 pubmed
  45. Boro M, Singh V, Balaji K. Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses. Sci Rep. 2016;6:37695 pubmed publisher
  46. Kim W, Khan S, Gvozdenovic Jeremic J, Kim Y, Dahlman J, Kim H, et al. Hippo signaling interactions with Wnt/?-catenin and Notch signaling repress liver tumorigenesis. J Clin Invest. 2017;127:137-152 pubmed publisher
  47. Matsumoto Y, La Rose J, Kent O, Wagner M, Narimatsu M, Levy A, et al. Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. J Clin Invest. 2016;126:4482-4496 pubmed publisher
  48. Vahid S, Thaper D, Gibson K, Bishop J, Zoubeidi A. Molecular chaperone Hsp27 regulates the Hippo tumor suppressor pathway in cancer. Sci Rep. 2016;6:31842 pubmed publisher
  49. Reginensi A, Enderle L, Gregorieff A, Johnson R, Wrana J, McNeill H. A critical role for NF2 and the Hippo pathway in branching morphogenesis. Nat Commun. 2016;7:12309 pubmed publisher
  50. Sayedyahossein S, Li Z, Hedman A, Morgan C, Sacks D. IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity. J Biol Chem. 2016;291:19261-73 pubmed publisher
  51. Feng X, Liu P, Zhou X, Li M, Li F, Wang Z, et al. Thromboxane A2 Activates YAP/TAZ Protein to Induce Vascular Smooth Muscle Cell Proliferation and Migration. J Biol Chem. 2016;291:18947-58 pubmed publisher
  52. Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;291:14761-72 pubmed publisher
  53. Thongon N, Castiglioni I, Zucal C, Latorre E, D Agostino V, Bauer I, et al. The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level. Oncotarget. 2016;7:26551-66 pubmed publisher
  54. Keyvani Chahi A, Martin C, Jones N. Nephrin Suppresses Hippo Signaling through the Adaptor Proteins Nck and WTIP. J Biol Chem. 2016;291:12799-808 pubmed publisher
  55. Dai X, Zhuang L, Wang D, Zhou T, Chang L, Gai R, et al. Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells. Oncotarget. 2016;7:6933-47 pubmed publisher
  56. Nishio M, Sugimachi K, Goto H, Wang J, Morikawa T, Miyachi Y, et al. Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice. Proc Natl Acad Sci U S A. 2016;113:E71-80 pubmed publisher
  57. Kim M, Kim M, Park S, Lee C, Lim D. Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition. EMBO Rep. 2016;17:64-78 pubmed publisher
  58. Meng Z, Moroishi T, Mottier Pavie V, Plouffe S, Hansen C, Hong A, et al. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nat Commun. 2015;6:8357 pubmed publisher
  59. Iglesias Bartolomé R, Torres D, Marone R, Feng X, Martin D, Simaan M, et al. Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nat Cell Biol. 2015;17:793-803 pubmed publisher
  60. Mo J, Meng Z, Kim Y, Park H, Hansen C, Kim S, et al. Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway. Nat Cell Biol. 2015;17:500-10 pubmed publisher
  61. Masuda K, Chiyoda T, Sugiyama N, Segura Cabrera A, Kabe Y, Ueki A, et al. LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C. PLoS ONE. 2015;10:e0118662 pubmed publisher
  62. Imajo M, Ebisuya M, Nishida E. Dual role of YAP and TAZ in renewal of the intestinal epithelium. Nat Cell Biol. 2015;17:7-19 pubmed publisher
  63. Li Q, Li S, Mana Capelli S, Roth Flach R, Danai L, Amcheslavsky A, et al. The conserved misshapen-warts-Yorkie pathway acts in enteroblasts to regulate intestinal stem cells in Drosophila. Dev Cell. 2014;31:291-304 pubmed publisher
  64. Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, et al. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. J Exp Med. 2014;211:2249-63 pubmed publisher
  65. Boin A, Couvelard A, Couderc C, Brito I, Filipescu D, Kalamarides M, et al. Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas. Neuro Oncol. 2014;16:1196-209 pubmed publisher
  66. Tumaneng K, Schlegelmilch K, Russell R, Yimlamai D, Basnet H, Mahadevan N, et al. YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29. Nat Cell Biol. 2012;14:1322-9 pubmed