This is a Validated Antibody Database (VAD) review about mouse Lat, based on 9 published articles (read how Labome selects the articles), using Lat antibody in all methods. It is aimed to help Labome visitors find the most suited Lat antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Lat synonym: p36-38; pp36; linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; linker protein

BioLegend
mouse monoclonal (11B.12)
  • western blot; mouse; fig s1
BioLegend Lat antibody (BioLegend, 11B.12) was used in western blot on mouse samples (fig s1). J Clin Invest (2018) ncbi
Abcam
rabbit polyclonal
  • western blot; human; 1:1000; fig 6
  • western blot; mouse; 1:1000; fig 8
In order to research the drive of early signaling and vesicle dynamics during T-cell activation by Aurora A, Abcam Lat antibody (Abcam, ab4476) was used in western blot on human samples at 1:1000 (fig 6) and in western blot on mouse samples at 1:1000 (fig 8). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 3d
In order to identify and characterize human ZAP-70 mutations associated with autoimmune disease, Abcam Lat antibody (Abcam, ab4476) was used in western blot on human samples (fig 3d). J Exp Med (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • immunocytochemistry; mouse; 1:25; loading ...; fig 3g
  • western blot; mouse; loading ...; fig 3e
Cell Signaling Technology Lat antibody (Cell Signaling, 9166) was used in immunocytochemistry on mouse samples at 1:25 (fig 3g) and in western blot on mouse samples (fig 3e). J Immunol (2016) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology Lat antibody (Cell Signaling Technology, 9166) was used in western blot on human samples . Mol Immunol (2015) ncbi
EMD Millipore
rabbit polyclonal
  • western blot; human; fig 4
In order to study how conformational changes control T cell receptor association and activity of Zap70, EMD Millipore Lat antibody (Millipore, 06-807) was used in western blot on human samples (fig 4). Nat Immunol (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; tbl 4
EMD Millipore Lat antibody (Millipore, 06-807) was used in western blot on human samples at 1:1000 (tbl 4). Methods Mol Biol (2014) ncbi
rabbit polyclonal
  • western blot; human
EMD Millipore Lat antibody (Millipore, 06-807) was used in western blot on human samples . Genes Immun (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
EMD Millipore Lat antibody (Millipore, 06-807) was used in western blot on mouse samples at 1:1000. J Immunol Methods (2013) ncbi
Articles Reviewed
  1. Muro R, Nitta T, Nakano K, Okamura T, Takayanagi H, Suzuki H. γδTCR recruits the Syk/PI3K axis to drive proinflammatory differentiation program. J Clin Invest. 2018;128:415-426 pubmed publisher
  2. Blas Rus N, Bustos Morán E, Perez de Castro I, de Carcer G, Borroto A, Camafeita E, et al. Aurora A drives early signalling and vesicle dynamics during T-cell activation. Nat Commun. 2016;7:11389 pubmed publisher
  3. Naik E, Dixit V. Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity. J Immunol. 2016;196:3438-51 pubmed publisher
  4. Chan A, Punwani D, Kadlecek T, Cowan M, Olson J, Mathes E, et al. A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70. J Exp Med. 2016;213:155-65 pubmed publisher
  5. Klammt C, Novotná L, Li D, Wolf M, Blount A, Zhang K, et al. T cell receptor dwell times control the kinase activity of Zap70. Nat Immunol. 2015;16:961-9 pubmed publisher
  6. Ebsen H, Lettau M, Kabelitz D, Janssen O. Subcellular localization and activation of ADAM proteases in the context of FasL shedding in T lymphocytes. Mol Immunol. 2015;65:416-28 pubmed publisher
  7. Cox S. Intracellular signaling of CTLs. Methods Mol Biol. 2014;1186:49-63 pubmed publisher
  8. Kłossowicz M, Marek Bukowiec K, Arbulo Echevarria M, Scirka B, Majkowski M, Sikorski A, et al. Identification of functional, short-lived isoform of linker for activation of T cells (LAT). Genes Immun. 2014;15:449-56 pubmed publisher
  9. Kłossowicz M, Scirka B, Suchanek J, Marek Bukowiec K, Kisielow P, Aguado E, et al. Assessment of caspase mediated degradation of linker for activation of T cells (LAT) at a single cell level. J Immunol Methods. 2013;389:9-17 pubmed publisher