This is a Validated Antibody Database (VAD) review about mouse Lamtor2, based on 7 published articles (read how Labome selects the articles), using Lamtor2 antibody in all methods. It is aimed to help Labome visitors find the most suited Lamtor2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Lamtor2 synonym: 2010111E04Rik; AL022628; Mapbpip; P14; Rab25; Robld3

Cell Signaling Technology
domestic rabbit monoclonal (D7C10)
  • western blot; mouse; loading ...; fig s2d
Cell Signaling Technology Lamtor2 antibody (Cell Signaling, 8145) was used in western blot on mouse samples (fig s2d). EMBO J (2022) ncbi
domestic rabbit monoclonal (D7C10)
  • western blot; mouse; loading ...; fig s6a
  • western blot; human; loading ...; fig s5c, s6b
Cell Signaling Technology Lamtor2 antibody (Cell Signaling, 8145) was used in western blot on mouse samples (fig s6a) and in western blot on human samples (fig s5c, s6b). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D7C10)
  • western blot; mouse; loading ...; fig 4d
Cell Signaling Technology Lamtor2 antibody (Cell Signaling, 8145) was used in western blot on mouse samples (fig 4d). Front Immunol (2020) ncbi
domestic rabbit monoclonal (D7C10)
  • western blot; mouse; loading ...; fig s2g
Cell Signaling Technology Lamtor2 antibody (Cell Signaling, 8145) was used in western blot on mouse samples (fig s2g). Science (2019) ncbi
domestic rabbit monoclonal (D7C10)
  • western blot; mouse; loading ...; fig 3c
In order to research the role of vacuolar-type H+-ATPase complex in liver in the accumulation of autophagic vacuoles and lysosomes, Cell Signaling Technology Lamtor2 antibody (Cell Signaling, 8145) was used in western blot on mouse samples (fig 3c). Autophagy (2017) ncbi
domestic rabbit monoclonal (D7C10)
  • western blot; mouse; 1:2000; loading ...; fig s1c
In order to describe how amino acids and Lamtor1 regulate macrophage polarization, Cell Signaling Technology Lamtor2 antibody (Cell Signaling, 8145) was used in western blot on mouse samples at 1:2000 (fig s1c). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D7C10)
  • western blot; human; 1:1000; fig s2
In order to elucidate the mechanisms by which mutant IDH1/2 contributes to oncogenesis, Cell Signaling Technology Lamtor2 antibody (Cell signaling, D7C10) was used in western blot on human samples at 1:1000 (fig s2). Nat Commun (2016) ncbi
Articles Reviewed
  1. Sun J, Liu Y, Hao X, Lin W, Su W, Chiang E, et al. LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function. EMBO J. 2022;41:e108119 pubmed publisher
  2. Nakatani T, Tsujimoto K, Park J, Jo T, Kimura T, Hayama Y, et al. The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II. Nat Commun. 2021;12:3333 pubmed publisher
  3. Ma C, Hunt J, Selenica M, Sanneh A, Sandusky Beltran L, Watler M, et al. Arginase 1 Insufficiency Precipitates Amyloid-β Deposition and Hastens Behavioral Impairment in a Mouse Model of Amyloidosis. Front Immunol. 2020;11:582998 pubmed publisher
  4. He M, Chaurushiya M, Webster J, Kummerfeld S, Reja R, Chaudhuri S, et al. Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1. Science. 2019;364:283-285 pubmed publisher
  5. Kissing S, Rudnik S, Damme M, Lüllmann Rauch R, Ichihara A, Kornak U, et al. Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes. Autophagy. 2017;13:670-685 pubmed publisher
  6. Kimura T, Nada S, Takegahara N, Okuno T, Nojima S, Kang S, et al. Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals. Nat Commun. 2016;7:13130 pubmed publisher
  7. Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher