This is a Validated Antibody Database (VAD) review about mouse Klrc1, based on 18 published articles (read how Labome selects the articles), using Klrc1 antibody in all methods. It is aimed to help Labome visitors find the most suited Klrc1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Klrc1 synonym: CD159a; NKG2A; NKG2B

Invitrogen
mouse monoclonal (16A11)
  • flow cytometry; mouse; loading ...; fig 2a
Invitrogen Klrc1 antibody (eBioscience, 16a11) was used in flow cytometry on mouse samples (fig 2a). Nature (2020) ncbi
rat monoclonal (20d5)
  • flow cytometry; mouse; 1:100; loading ...; fig 5
Invitrogen Klrc1 antibody (eBioscience, 11-5896-82) was used in flow cytometry on mouse samples at 1:100 (fig 5). elife (2018) ncbi
mouse monoclonal (16A11)
  • flow cytometry; mouse; loading ...; fig 6e
Invitrogen Klrc1 antibody (eBioscience, 16a11) was used in flow cytometry on mouse samples (fig 6e). J Exp Med (2019) ncbi
mouse monoclonal (16A11)
  • flow cytometry; mouse; loading ...; fig 4a
In order to investigate the important of Ly49A ITIM signaling in NK-cell effector inhibition, licensing, and receptor repertoire development, Invitrogen Klrc1 antibody (eBiosciences, 16a11) was used in flow cytometry on mouse samples (fig 4a). Proc Natl Acad Sci U S A (2017) ncbi
rat monoclonal (20d5)
  • flow cytometry; mouse; loading ...; fig 2
In order to determine the function of the SLAM family of proteins in natural killer cells, Invitrogen Klrc1 antibody (eBioscience, 20d5) was used in flow cytometry on mouse samples (fig 2). J Exp Med (2016) ncbi
rat monoclonal (20d5)
  • flow cytometry; mouse; fig s2b
Invitrogen Klrc1 antibody (eBioscience, 20d5) was used in flow cytometry on mouse samples (fig s2b). Immunity (2016) ncbi
rat monoclonal (20d5)
  • flow cytometry; mouse; 1:100; fig s4
In order to assess the role of NLRC5 to NK-T-cell crosstalk, Invitrogen Klrc1 antibody (eBioscience, 20d5) was used in flow cytometry on mouse samples at 1:100 (fig s4). Nat Commun (2016) ncbi
rat monoclonal (20d5)
  • flow cytometry; mouse; fig 5
Invitrogen Klrc1 antibody (eBioscience, 20D5) was used in flow cytometry on mouse samples (fig 5). Nat Immunol (2015) ncbi
BioLegend
mouse monoclonal (16A11)
  • flow cytometry; mouse; 1:100; loading ...; fig 3d
BioLegend Klrc1 antibody (Biolegend, 142809) was used in flow cytometry on mouse samples at 1:100 (fig 3d). Development (2022) ncbi
mouse monoclonal (16A11)
  • flow cytometry; mouse; loading ...; fig 3d
BioLegend Klrc1 antibody (Biolegend, 16A11) was used in flow cytometry on mouse samples (fig 3d). J Immunother Cancer (2021) ncbi
mouse monoclonal (16A11)
  • flow cytometry; mouse; fig 5b
BioLegend Klrc1 antibody (BioLegend, 16A11) was used in flow cytometry on mouse samples (fig 5b). Nat Commun (2016) ncbi
Miltenyi Biotec
rat monoclonal (20d5)
  • immunohistochemistry - frozen section; mouse; loading ...; fig s6
Miltenyi Biotec Klrc1 antibody (Miltenyi Biotec, 130-105-619) was used in immunohistochemistry - frozen section on mouse samples (fig s6). Sci Rep (2022) ncbi
rat monoclonal (20d5)
  • flow cytometry; mouse; loading ...; fig 2a, 3a
Miltenyi Biotec Klrc1 antibody (Miltenyi Biotec, 130-105-566) was used in flow cytometry on mouse samples (fig 2a, 3a). Cell (2018) ncbi
BD Biosciences
rat monoclonal (20d5)
  • flow cytometry; mouse; loading ...; fig 2a
BD Biosciences Klrc1 antibody (BD Biosciences, 20d5) was used in flow cytometry on mouse samples (fig 2a). Nature (2020) ncbi
rat monoclonal (20d5)
  • flow cytometry; mouse; loading ...; fig 6a
BD Biosciences Klrc1 antibody (BD, 20d5) was used in flow cytometry on mouse samples (fig 6a). J Immunol (2018) ncbi
rat monoclonal (20d5)
  • flow cytometry; mouse; 1:100; loading ...; fig 3d
In order to find an alternative pathway of NK-cell development driven by IL-12, BD Biosciences Klrc1 antibody (BD Biosciences, 20d5) was used in flow cytometry on mouse samples at 1:100 (fig 3d). Nat Commun (2016) ncbi
rat monoclonal (20d5)
  • flow cytometry; mouse; loading ...; fig 3d
In order to investigate the ability of PTEN to regulate natural killer cell function, BD Biosciences Klrc1 antibody (BD Biosciences, 20d5) was used in flow cytometry on mouse samples (fig 3d). J Immunol (2015) ncbi
rat monoclonal (20d5)
  • flow cytometry; mouse
BD Biosciences Klrc1 antibody (BD Pharmingen, 20d5) was used in flow cytometry on mouse samples . Eur J Immunol (2014) ncbi
rat monoclonal (20d5)
  • flow cytometry; mouse
BD Biosciences Klrc1 antibody (BD Biosciences, 20d5) was used in flow cytometry on mouse samples . J Immunol (2014) ncbi
Articles Reviewed
  1. Meléndez E, Chondronasiou D, Mosteiro L, Mart xed nez de Villarreal J, Fern xe1 ndez Alfara M, Lynch C, et al. Natural killer cells act as an extrinsic barrier for in vivo reprogramming. Development. 2022;149: pubmed publisher
  2. Kinkhabwala A, Herbel C, Pankratz J, Yushchenko D, R xfc berg S, Praveen P, et al. MACSima imaging cyclic staining (MICS) technology reveals combinatorial target pairs for CAR T cell treatment of solid tumors. Sci Rep. 2022;12:1911 pubmed publisher
  3. Brownlie D, Doughty Shenton D, Yh Soong D, Nixon C, O Carragher N, M Carlin L, et al. Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β. J Immunother Cancer. 2021;9: pubmed publisher
  4. Abadie V, Kim S, Lejeune T, Palanski B, Ernest J, Tastet O, et al. IL-15, gluten and HLA-DQ8 drive tissue destruction in coeliac disease. Nature. 2020;578:600-604 pubmed publisher
  5. Wang X, Piersma S, Nelson C, Dai Y, Christensen T, Lazear E, et al. A herpesvirus encoded Qa-1 mimic inhibits natural killer cell cytotoxicity through CD94/NKG2A receptor engagement. elife. 2018;7: pubmed publisher
  6. Bern M, Parikh B, Yang L, Beckman D, Poursine Laurent J, Yokoyama W. Inducible down-regulation of MHC class I results in natural killer cell tolerance. J Exp Med. 2019;216:99-116 pubmed publisher
  7. Andre P, Denis C, Soulas C, Bourbon Caillet C, Lopez J, Arnoux T, et al. Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells. Cell. 2018;175:1731-1743.e13 pubmed publisher
  8. Tinoco R, Carrette F, Henriquez M, Fujita Y, Bradley L. Fucosyltransferase Induction during Influenza Virus Infection Is Required for the Generation of Functional Memory CD4+ T Cells. J Immunol. 2018;200:2690-2702 pubmed publisher
  9. Bern M, Beckman D, Ebihara T, Taffner S, Poursine Laurent J, White J, et al. Immunoreceptor tyrosine-based inhibitory motif-dependent functions of an MHC class I-specific NK cell receptor. Proc Natl Acad Sci U S A. 2017;114:E8440-E8447 pubmed publisher
  10. Ohs I, Van Den Broek M, Nussbaum K, MUNZ C, Arnold S, Quezada S, et al. Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis. Nat Commun. 2016;7:13708 pubmed publisher
  11. Tripathi D, Venkatasubramanian S, Cheekatla S, Paidipally P, Welch E, Tvinnereim A, et al. A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice. Nat Commun. 2016;7:13896 pubmed publisher
  12. Guo H, Cranert S, Lu Y, Zhong M, Zhang S, Chen J, et al. Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1. J Exp Med. 2016;213:2187-207 pubmed publisher
  13. Wang S, Xia P, Chen Y, Huang G, Xiong Z, Liu J, et al. Natural Killer-like B Cells Prime Innate Lymphocytes against Microbial Infection. Immunity. 2016;45:131-44 pubmed publisher
  14. Ludigs K, Jandus C, Utzschneider D, Staehli F, Bessoles S, Dang A, et al. NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nat Commun. 2016;7:10554 pubmed publisher
  15. Wensveen F, Jelenčić V, Valentić S, Šestan M, Wensveen T, Theurich S, et al. NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nat Immunol. 2015;16:376-85 pubmed publisher
  16. Briercheck E, Trotta R, Chen L, Hartlage A, Cole J, Cole T, et al. PTEN is a negative regulator of NK cell cytolytic function. J Immunol. 2015;194:1832-40 pubmed publisher
  17. Wei H, Nash W, Makrigiannis A, Brown M. Impaired NK-cell education diminishes resistance to murine CMV infection. Eur J Immunol. 2014;44:3273-82 pubmed publisher
  18. Smith T, Verdeil G, Marquardt K, Sherman L. Contribution of TCR signaling strength to CD8+ T cell peripheral tolerance mechanisms. J Immunol. 2014;193:3409-16 pubmed publisher