This is a Validated Antibody Database (VAD) review about mouse Klra6, based on 17 published articles (read how Labome selects the articles), using Klra6 antibody in all methods. It is aimed to help Labome visitors find the most suited Klra6 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Klra6 synonym: Ly49f; ly-49f

Invitrogen
mouse monoclonal (3D10)
  • flow cytometry; mouse; 1:100; loading ...
Invitrogen Klra6 antibody (Thermo Fisher Scientific, 3D10) was used in flow cytometry on mouse samples at 1:100. elife (2020) ncbi
mouse monoclonal (3D10)
  • flow cytometry; mouse; loading ...; fig 6e
Invitrogen Klra6 antibody (eBioscience, 3D10) was used in flow cytometry on mouse samples (fig 6e). J Exp Med (2019) ncbi
mouse monoclonal (3D10)
  • flow cytometry; mouse; loading ...; fig 5b
Invitrogen Klra6 antibody (eBioscience, 3D10) was used in flow cytometry on mouse samples (fig 5b). PLoS Pathog (2018) ncbi
mouse monoclonal (A1 (Ly49A))
  • flow cytometry; mouse; loading ...; fig s1a
Invitrogen Klra6 antibody (eBioscience, A1) was used in flow cytometry on mouse samples (fig s1a). Front Immunol (2018) ncbi
mouse monoclonal (3D10)
  • flow cytometry; mouse; loading ...; fig s1a
Invitrogen Klra6 antibody (eBioscience, 3D10) was used in flow cytometry on mouse samples (fig s1a). Front Immunol (2018) ncbi
rat monoclonal (eBio4D11 (4D11))
  • flow cytometry; mouse; loading ...; fig s1a
Invitrogen Klra6 antibody (eBioscience, 4D11) was used in flow cytometry on mouse samples (fig s1a). Front Immunol (2018) ncbi
rat monoclonal (eBio4E5 (4E5))
  • flow cytometry; mouse; loading ...; fig s1a
Invitrogen Klra6 antibody (eBioscience, 4E5) was used in flow cytometry on mouse samples (fig s1a). Front Immunol (2018) ncbi
rat monoclonal (eBio4E5 (4E5))
  • flow cytometry; mouse; loading ...; fig 6b
In order to investigate the important of Ly49A ITIM signaling in NK-cell effector inhibition, licensing, and receptor repertoire development, Invitrogen Klra6 antibody (eBiosciences, eBio4E5) was used in flow cytometry on mouse samples (fig 6b). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (YLI-90)
  • flow cytometry; mouse; loading ...; fig 6b
In order to investigate the important of Ly49A ITIM signaling in NK-cell effector inhibition, licensing, and receptor repertoire development, Invitrogen Klra6 antibody (eBiosciences, YLI-90) was used in flow cytometry on mouse samples (fig 6b). Proc Natl Acad Sci U S A (2017) ncbi
rat monoclonal (CM4)
  • flow cytometry; mouse; loading ...; fig 6b
In order to investigate the important of Ly49A ITIM signaling in NK-cell effector inhibition, licensing, and receptor repertoire development, Invitrogen Klra6 antibody (eBiosciences, CM4) was used in flow cytometry on mouse samples (fig 6b). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (3D10)
  • flow cytometry; mouse; loading ...; fig 6b
In order to investigate the important of Ly49A ITIM signaling in NK-cell effector inhibition, licensing, and receptor repertoire development, Invitrogen Klra6 antibody (eBiosciences, 3D10) was used in flow cytometry on mouse samples (fig 6b). Proc Natl Acad Sci U S A (2017) ncbi
rat monoclonal (eBio4D11 (4D11))
  • flow cytometry; mouse; 1:100; loading ...; fig 3d
In order to find an alternative pathway of NK-cell development driven by IL-12, Invitrogen Klra6 antibody (eBioscience, eBio4D1) was used in flow cytometry on mouse samples at 1:100 (fig 3d). Nat Commun (2016) ncbi
mouse monoclonal (A1 (Ly49A))
  • flow cytometry; mouse; 1:100; loading ...; fig 3d
In order to find an alternative pathway of NK-cell development driven by IL-12, Invitrogen Klra6 antibody (eBioscience, A1) was used in flow cytometry on mouse samples at 1:100 (fig 3d). Nat Commun (2016) ncbi
mouse monoclonal (YLI-90)
  • flow cytometry; mouse; 1:100; loading ...; fig 3d
In order to find an alternative pathway of NK-cell development driven by IL-12, Invitrogen Klra6 antibody (eBioscience, YLI-90) was used in flow cytometry on mouse samples at 1:100 (fig 3d). Nat Commun (2016) ncbi
Syrian golden hamster monoclonal (14B11)
  • flow cytometry; mouse; loading ...; fig 2
In order to determine the function of the SLAM family of proteins in natural killer cells, Invitrogen Klra6 antibody (eBioscience, 14B11) was used in flow cytometry on mouse samples (fig 2). J Exp Med (2016) ncbi
mouse monoclonal (YLI-90)
  • flow cytometry; human; loading ...; fig 2d
Invitrogen Klra6 antibody (eBioscience, 15-414) was used in flow cytometry on human samples (fig 2d). Sci Rep (2016) ncbi
Syrian golden hamster monoclonal (14B11)
  • flow cytometry; mouse; fig 3
In order to study murine nasal passages to identify and analyze natural killer cells, Invitrogen Klra6 antibody (eBiosciences, 14B11) was used in flow cytometry on mouse samples (fig 3). PLoS ONE (2015) ncbi
Syrian golden hamster monoclonal (14B11)
  • flow cytometry; mouse; fig 3
In order to study how DNAM-1 controls NK cell-mediated cytotoxicity and cytokine production, Invitrogen Klra6 antibody (eBioscience, 14B11) was used in flow cytometry on mouse samples (fig 3). J Exp Med (2015) ncbi
mouse monoclonal (YLI-90)
  • flow cytometry; mouse; fig s1
Invitrogen Klra6 antibody (eBioscience, YLI-90) was used in flow cytometry on mouse samples (fig s1). Nat Immunol (2015) ncbi
mouse monoclonal (3D10)
  • flow cytometry; mouse; fig s1
Invitrogen Klra6 antibody (eBioscience, 3D10) was used in flow cytometry on mouse samples (fig s1). Nat Immunol (2015) ncbi
BioLegend
rat monoclonal (YE1/48.10.6)
  • blocking or activating experiments; mouse; fig 2d
  • flow cytometry; mouse; loading ...; fig 3d
BioLegend Klra6 antibody (BioLegend, YE1/48.10.6) was used in blocking or activating experiments on mouse samples (fig 2d) and in flow cytometry on mouse samples (fig 3d). J Immunother Cancer (2021) ncbi
Syrian golden hamster monoclonal (14B11)
  • flow cytometry; mouse; loading ...; fig 3d
BioLegend Klra6 antibody (Biolegend, 14B11) was used in flow cytometry on mouse samples (fig 3d). J Immunother Cancer (2021) ncbi
mouse monoclonal (3D10)
  • flow cytometry; mouse; loading ...; fig 1b
BioLegend Klra6 antibody (BioLegend, 3D10) was used in flow cytometry on mouse samples (fig 1b). J Immunol (2019) ncbi
rat monoclonal (4E5)
  • flow cytometry; mouse; loading ...; fig s6d
BioLegend Klra6 antibody (Biolegend, 4E5) was used in flow cytometry on mouse samples (fig s6d). Science (2018) ncbi
rat monoclonal (4E5)
  • flow cytometry; mouse; loading ...; fig 1f
BioLegend Klra6 antibody (BioLegend, 4E5) was used in flow cytometry on mouse samples (fig 1f). Am J Transplant (2019) ncbi
rat monoclonal (4E5)
  • flow cytometry; mouse; 1:100; loading ...; fig 3d
In order to find an alternative pathway of NK-cell development driven by IL-12, BioLegend Klra6 antibody (Biolegend, 4E5) was used in flow cytometry on mouse samples at 1:100 (fig 3d). Nat Commun (2016) ncbi
rat monoclonal (YE1/48.10.6)
  • flow cytometry; mouse; fig 3
In order to study the functions of WASp knock out natural killer cells, BioLegend Klra6 antibody (Biolegend, YEI/48) was used in flow cytometry on mouse samples (fig 3). Sci Rep (2016) ncbi
mouse monoclonal (3D10)
  • flow cytometry; mouse; 1:100; fig s4
In order to assess the role of NLRC5 to NK-T-cell crosstalk, BioLegend Klra6 antibody (BioLegend, 3D10) was used in flow cytometry on mouse samples at 1:100 (fig s4). Nat Commun (2016) ncbi
BD Biosciences
mouse monoclonal (HBF-719)
  • flow cytometry; mouse; loading ...; fig 6b
In order to investigate the important of Ly49A ITIM signaling in NK-cell effector inhibition, licensing, and receptor repertoire development, BD Biosciences Klra6 antibody (BD Biosciences, HBF-719) was used in flow cytometry on mouse samples (fig 6b). Proc Natl Acad Sci U S A (2017) ncbi
Articles Reviewed
  1. Brownlie D, Doughty Shenton D, Yh Soong D, Nixon C, O Carragher N, M Carlin L, et al. Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β. J Immunother Cancer. 2021;9: pubmed publisher
  2. Piersma S, Poursine Laurent J, Yang L, Barber G, Parikh B, Yokoyama W. Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING. elife. 2020;9: pubmed publisher
  3. McLaren J, Clement M, Marsden M, Miners K, Llewellyn Lacey S, Grant E, et al. IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine. J Immunol. 2019;202:943-955 pubmed publisher
  4. Ruscetti M, Leibold J, Bott M, Fennell M, Kulick A, Salgado N, et al. NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination. Science. 2018;362:1416-1422 pubmed publisher
  5. Bern M, Parikh B, Yang L, Beckman D, Poursine Laurent J, Yokoyama W. Inducible down-regulation of MHC class I results in natural killer cell tolerance. J Exp Med. 2019;216:99-116 pubmed publisher
  6. Jensen I, Winborn C, Fosdick M, Shao P, Tremblay M, Shan Q, et al. Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections. PLoS Pathog. 2018;14:e1007405 pubmed publisher
  7. Mahr B, Pilat N, Granofszky N, Wiletel M, Muckenhuber M, Maschke S, et al. Hybrid resistance to parental bone marrow grafts in nonlethally irradiated mice. Am J Transplant. 2019;19:591-596 pubmed publisher
  8. Abel A, Tiwari A, Gerbec Z, Siebert J, Yang C, Schloemer N, et al. IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells. Front Immunol. 2018;9:1168 pubmed publisher
  9. Bern M, Beckman D, Ebihara T, Taffner S, Poursine Laurent J, White J, et al. Immunoreceptor tyrosine-based inhibitory motif-dependent functions of an MHC class I-specific NK cell receptor. Proc Natl Acad Sci U S A. 2017;114:E8440-E8447 pubmed publisher
  10. Ohs I, Van Den Broek M, Nussbaum K, MUNZ C, Arnold S, Quezada S, et al. Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis. Nat Commun. 2016;7:13708 pubmed publisher
  11. Guo H, Cranert S, Lu Y, Zhong M, Zhang S, Chen J, et al. Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1. J Exp Med. 2016;213:2187-207 pubmed publisher
  12. Kritikou J, Dahlberg C, Baptista M, Wagner A, Banerjee P, Gwalani L, et al. IL-2 in the tumor microenvironment is necessary for Wiskott-Aldrich syndrome protein deficient NK cells to respond to tumors in vivo. Sci Rep. 2016;6:30636 pubmed publisher
  13. Harfuddin Z, Dharmadhikari B, Wong S, Duan K, Poidinger M, Kwajah S, et al. Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype. Sci Rep. 2016;6:29712 pubmed publisher
  14. Ludigs K, Jandus C, Utzschneider D, Staehli F, Bessoles S, Dang A, et al. NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nat Commun. 2016;7:10554 pubmed publisher
  15. Okada K, Sato S, Sato A, Mandelboim O, Yamasoba T, Kiyono H. Identification and Analysis of Natural Killer Cells in Murine Nasal Passages. PLoS ONE. 2015;10:e0142920 pubmed publisher
  16. Zhang Z, Wu N, Lu Y, Davidson D, Colonna M, Veillette A. DNAM-1 controls NK cell activation via an ITT-like motif. J Exp Med. 2015;212:2165-82 pubmed publisher
  17. Wensveen F, Jelenčić V, Valentić S, Šestan M, Wensveen T, Theurich S, et al. NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nat Immunol. 2015;16:376-85 pubmed publisher