This is a Validated Antibody Database (VAD) review about mouse Kcnn4, based on 5 published articles (read how Labome selects the articles), using Kcnn4 antibody in all methods. It is aimed to help Labome visitors find the most suited Kcnn4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Kcnn4 synonym: IK1; IKCA1; KCA4; KCa3.1; SK4; SKCas; mIKCa1; intermediate conductance calcium-activated potassium channel protein 4; SKCa 4; SKCa4

Proteintech Group
mouse monoclonal (2A6G5)
  • western blot; rat; fig 3
Proteintech Group Kcnn4 antibody (Proteintech, 60276-1-Ig) was used in western blot on rat samples (fig 3). Acta Cardiol Sin (2017) ncbi
Alomone Labs
mouse monoclonal
  • immunocytochemistry; mouse; 1:100; fig 3
In order to utilize the mechanosensitive TRPV4 channel in the collecting duct system of kidney that is coupled to expression of a diverse array of Ca2+-activated K+ channels (SK1/3, IK1, BK), Alomone Labs Kcnn4 antibody (Alomone, ALM-051) was used in immunocytochemistry on mouse samples at 1:100 (fig 3). PLoS ONE (2016) ncbi
Invitrogen
rabbit polyclonal
  • immunohistochemistry; human; 1:100; fig 3c
In order to measure mRNA expression and functional changes altered in response to edema and increased intracranial pressure in human neurons, Invitrogen Kcnn4 antibody (Thermo, PA5-33875) was used in immunohistochemistry on human samples at 1:100 (fig 3c). Acta Neuropathol Commun (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; fig 5
  • western blot; mouse; 1:1000; fig 1
In order to utilize the mechanosensitive TRPV4 channel in the collecting duct system of kidney that is coupled to expression of a diverse array of Ca2+-activated K+ channels (SK1/3, IK1, BK), Invitrogen Kcnn4 antibody (Thermo Fisher Scientific, PA5-33875) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 5) and in western blot on mouse samples at 1:1000 (fig 1). PLoS ONE (2016) ncbi
Sigma-Aldrich
rabbit polyclonal
  • immunohistochemistry; human; fig s2a
  • western blot; human; 1:1000; fig s1
Sigma-Aldrich Kcnn4 antibody (Sigma, P4997) was used in immunohistochemistry on human samples (fig s2a) and in western blot on human samples at 1:1000 (fig s1). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; mouse
Sigma-Aldrich Kcnn4 antibody (Sigma-Aldrich, P4997) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
Articles Reviewed
  1. Dong P, Liu M, Liu C. Exenatide Inhibits the KCa3.1 Channels of Aortic Vascular Smooth Muscle in Diabetic Rats. Acta Cardiol Sin. 2017;33:648-655 pubmed publisher
  2. Faragó N, Kocsis Ã, Braskó C, Lovas S, Rózsa M, Baka J, et al. Human neuronal changes in brain edema and increased intracranial pressure. Acta Neuropathol Commun. 2016;4:78 pubmed publisher
  3. Li Y, Hu H, Butterworth M, Tian J, Zhu M, O Neil R. Expression of a Diverse Array of Ca2+-Activated K+ Channels (SK1/3, IK1, BK) that Functionally Couple to the Mechanosensitive TRPV4 Channel in the Collecting Duct System of Kidney. PLoS ONE. 2016;11:e0155006 pubmed publisher
  4. Arthur G, Duffy S, Roach K, Hirst R, Shikotra A, Gaillard E, et al. KCa3.1 K+ Channel Expression and Function in Human Bronchial Epithelial Cells. PLoS ONE. 2015;10:e0145259 pubmed publisher
  5. Wandall Frostholm C, Skaarup L, Sadda V, Nielsen G, Hedegaard E, Mogensen S, et al. Pulmonary hypertension in wild type mice and animals with genetic deficit in KCa2.3 and KCa3.1 channels. PLoS ONE. 2014;9:e97687 pubmed publisher