This is a Validated Antibody Database (VAD) review about mouse Itgb3, based on 37 published articles (read how Labome selects the articles), using Itgb3 antibody in all methods. It is aimed to help Labome visitors find the most suited Itgb3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Itgb3 synonym: CD61; GP3A; INGRB3

Knockout validation
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:300; loading ...; fig 1c
Cell Signaling Technology Itgb3 antibody (Cell Signaling, 4702) was used in western blot knockout validation on human samples at 1:300 (fig 1c). elife (2021) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; mouse; fig s1b
Cell Signaling Technology Itgb3 antibody (CST, 4702) was used in western blot knockout validation on mouse samples (fig s1b). Mol Med Rep (2021) ncbi
BioLegend
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • flow cytometry; mouse
BioLegend Itgb3 antibody (Biolegend, 104302) was used in flow cytometry on mouse samples . Cancer Cell (2021) ncbi
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • flow cytometry; mouse; loading ...; fig 4a
BioLegend Itgb3 antibody (Biolegend, 2C9G2) was used in flow cytometry on mouse samples (fig 4a). J Exp Med (2018) ncbi
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • flow cytometry; mouse; fig 3
BioLegend Itgb3 antibody (Biolegend, 2C9.G2) was used in flow cytometry on mouse samples (fig 3). PLoS ONE (2016) ncbi
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • flow cytometry; mouse; 1:100; fig 2
BioLegend Itgb3 antibody (Biolegend, 104308) was used in flow cytometry on mouse samples at 1:100 (fig 2). J Hematol Oncol (2016) ncbi
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • flow cytometry; mouse; 1:10
BioLegend Itgb3 antibody (Biolegend, 104308) was used in flow cytometry on mouse samples at 1:10. Nature (2016) ncbi
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • blocking or activating experiments; mouse; 10 ug/ml; fig 5
In order to report that Thy-1 is a regulator of fibroblast rigidity sensing, BioLegend Itgb3 antibody (BioLegend, 2C9.G2) was used in blocking or activating experiments on mouse samples at 10 ug/ml (fig 5). J Cell Biol (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-11)
  • western blot; mouse; loading ...; fig 1a
Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz Technology, sc-365679) was used in western blot on mouse samples (fig 1a). Brain Res (2018) ncbi
mouse monoclonal (B-7)
  • western blot; human; 1:200; loading ...; fig 5a
Santa Cruz Biotechnology Itgb3 antibody (SantaCruz, sc-46655) was used in western blot on human samples at 1:200 (fig 5a). Oncotarget (2016) ncbi
mouse monoclonal (23C6)
  • immunocytochemistry; human; fig 3
In order to study inhibition of the FAK/PI3K/Akt/mTOR signaling pathway through av-beta-3 integrin interaction by the anti-tumor NC1 domain of collagen XIX, Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz, sc7312) was used in immunocytochemistry on human samples (fig 3). Oncotarget (2016) ncbi
mouse monoclonal (SAP)
  • western blot; human
In order to determine the role of growth factors in EMT, Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz, SAP) was used in western blot on human samples . PLoS ONE (2015) ncbi
mouse monoclonal (B-7)
  • western blot; human
Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz Biotechnology, sc-46655) was used in western blot on human samples . Colloids Surf B Biointerfaces (2015) ncbi
mouse monoclonal (23C6)
  • immunoprecipitation; human; 1:200
  • western blot; human; 1:200; fig 1
In order to test if integrin alphavbeta3 signaling promotes the release of intracellular calcium and contributes to viral entry and spread, Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz Biotechnology, sc7312) was used in immunoprecipitation on human samples at 1:200 and in western blot on human samples at 1:200 (fig 1). J Virol (2014) ncbi
mouse monoclonal (BV4)
  • flow cytometry; human
Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz, sc-52685) was used in flow cytometry on human samples . Biomaterials (2014) ncbi
mouse monoclonal (23C6)
  • western blot; mouse
In order to study the role of the Rac1 GTPase the shaping of the ocular lens, Santa Cruz Biotechnology Itgb3 antibody (Santa, SC-7312) was used in western blot on mouse samples . Dev Biol (2011) ncbi
Novus Biologicals
domestic rabbit monoclonal (SJ19-09)
  • western blot; mouse; 1:1000; loading ...; fig 5d
Novus Biologicals Itgb3 antibody (Novus Biologicals, SJ19-09) was used in western blot on mouse samples at 1:1000 (fig 5d). Theranostics (2021) ncbi
mouse monoclonal (BV4)
  • western blot; human; 1:1000; fig 5s1b
Novus Biologicals Itgb3 antibody (Novus, NB600-1342) was used in western blot on human samples at 1:1000 (fig 5s1b). elife (2019) ncbi
Abcam
domestic rabbit monoclonal (EPR2342)
  • western blot; human; 1:1000; loading ...; fig 1s1a
  • western blot; mouse; 1:1000; fig 1s1a
Abcam Itgb3 antibody (Abcam, ab119992) was used in western blot on human samples at 1:1000 (fig 1s1a) and in western blot on mouse samples at 1:1000 (fig 1s1a). elife (2019) ncbi
domestic rabbit monoclonal (EPR2342)
  • western blot; human; 1:1000; loading ...; fig 4d
In order to determine if the extracellular matrix components of human skin fibroblasts change under non-stretch, static stretch, or cyclic stretch conditions, Abcam Itgb3 antibody (Abcam, ab119992) was used in western blot on human samples at 1:1000 (fig 4d). Exp Ther Med (2016) ncbi
domestic rabbit monoclonal (EPR2342)
  • western blot; human
Abcam Itgb3 antibody (Abcam, ab119992) was used in western blot on human samples . Int J Mol Sci (2014) ncbi
Invitrogen
hamsters monoclonal (2C9.G3)
  • flow cytometry; human; 1:50; fig 2a
Invitrogen Itgb3 antibody (eBioscience/Thermo, 12-0611-82) was used in flow cytometry on human samples at 1:50 (fig 2a). Stem Cells (2019) ncbi
hamsters monoclonal (2C9.G3)
  • flow cytometry; mouse; loading ...; fig 1c
Invitrogen Itgb3 antibody (Thermofisher, 2C9.G2) was used in flow cytometry on mouse samples (fig 1c). J Leukoc Biol (2019) ncbi
Miltenyi Biotec
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • flow cytometry; rat; fig 5a
In order to study the role of exosomes in acute lung injury and the macrophage activation, Miltenyi Biotec Itgb3 antibody (Miltenyi Biotec, 2C9.G2) was used in flow cytometry on rat samples (fig 5a). FASEB J (2018) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:300; loading ...; fig 1c
Cell Signaling Technology Itgb3 antibody (Cell Signaling, 4702) was used in western blot knockout validation on human samples at 1:300 (fig 1c). elife (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; fig s1b
Cell Signaling Technology Itgb3 antibody (CST, 4702) was used in western blot knockout validation on mouse samples (fig s1b). Mol Med Rep (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig s6
Cell Signaling Technology Itgb3 antibody (Cell Signaling, 4702) was used in western blot on mouse samples (fig s6). J Clin Invest (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2j
  • western blot; human; 1:1000; loading ...; fig 2c
Cell Signaling Technology Itgb3 antibody (Cell Signaling, 4702) was used in western blot on mouse samples at 1:1000 (fig 2j) and in western blot on human samples at 1:1000 (fig 2c). Nature (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 3
Cell Signaling Technology Itgb3 antibody (Cell signaling, 4702) was used in western blot on human samples (fig 3). Sci Rep (2016) ncbi
BD Biosciences
hamsters monoclonal (2C9.G2)
  • flow cytometry; mouse; loading ...; fig 4a
BD Biosciences Itgb3 antibody (BD, 561910) was used in flow cytometry on mouse samples (fig 4a). Front Cell Dev Biol (2021) ncbi
hamsters monoclonal (2C9.G2)
  • flow cytometry; mouse; loading ...; fig 1a
BD Biosciences Itgb3 antibody (BD Pharmingen, 553347) was used in flow cytometry on mouse samples (fig 1a). Am J Cancer Res (2021) ncbi
hamsters monoclonal (2C9.G2)
  • flow cytometry; mouse; fig s1e
BD Biosciences Itgb3 antibody (BD Pharmingen, 553347) was used in flow cytometry on mouse samples (fig s1e). Mol Med Rep (2021) ncbi
hamsters monoclonal (2C9.G2)
  • flow cytometry; mouse; fig st2
BD Biosciences Itgb3 antibody (BD Pharmingen, 561911) was used in flow cytometry on mouse samples (fig st2). Nat Commun (2018) ncbi
rat monoclonal (FIB504)
  • flow cytometry; human; loading ...; fig s4b
BD Biosciences Itgb3 antibody (BD Biosciences, 564283) was used in flow cytometry on human samples (fig s4b). Eur J Immunol (2018) ncbi
hamsters monoclonal (2C9.G2)
  • flow cytometry; mouse; 1:200; fig 1s2
In order to determine the role of Kindlin-2 tp activate integrins by cooperating with talin and induction of cell spreading by directly binding paxillin, BD Biosciences Itgb3 antibody (PharMingen, 553345) was used in flow cytometry on mouse samples at 1:200 (fig 1s2). elife (2016) ncbi
hamsters monoclonal (2C9.G2)
  • flow cytometry; mouse
BD Biosciences Itgb3 antibody (BD Biosciences, 553347) was used in flow cytometry on mouse samples . Liver Int (2015) ncbi
hamsters monoclonal (2C9.G2)
  • flow cytometry; mouse; 1:50; fig 2a
BD Biosciences Itgb3 antibody (BD, 2C9.G2) was used in flow cytometry on mouse samples at 1:50 (fig 2a). Nature (2015) ncbi
hamsters monoclonal (2C9.G2)
  • flow cytometry; mouse
BD Biosciences Itgb3 antibody (BD Pharmingen, 553343) was used in flow cytometry on mouse samples . Cancer Res (2014) ncbi
hamsters monoclonal (2C9.G2)
  • flow cytometry; mouse
BD Biosciences Itgb3 antibody (BD, 553347) was used in flow cytometry on mouse samples . J Biol Chem (2014) ncbi
hamsters monoclonal (2C9.G2)
  • flow cytometry; mouse
BD Biosciences Itgb3 antibody (Becton-Dickinson, 2C9.G2) was used in flow cytometry on mouse samples . Biochim Biophys Acta (2013) ncbi
Articles Reviewed
  1. Shao C, Lou P, Liu R, Bi X, Li G, Yang X, et al. Hormone-Responsive BMP Signaling Expands Myoepithelial Cell Lineages and Prevents Alveolar Precocity in Mammary Gland. Front Cell Dev Biol. 2021;9:691050 pubmed publisher
  2. Zheleznyak A, Mixdorf M, Marsala L, Prior J, Yang X, Cui G, et al. Orthogonal targeting of osteoclasts and myeloma cells for radionuclide stimulated dynamic therapy induces multidimensional cell death pathways. Theranostics. 2021;11:7735-7754 pubmed publisher
  3. Hutton C, Heider F, Blanco Gómez A, Banyard A, Kononov A, Zhang X, et al. Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity. Cancer Cell. 2021;: pubmed publisher
  4. Sribenja S, Maguire O, Attwood K, Buas M, Palmer J, Ambrosone C, et al. Deletion of Foxa1 in the mouse mammary gland results in abnormal accumulation of luminal progenitor cells: a link between reproductive factors and ER-/TNBC breast cancer?. Am J Cancer Res. 2021;11:3263-3270 pubmed
  5. Dieterle M, Solà Riera C, Ye C, Goodfellow S, Mittler E, Kasikci E, et al. Genetic depletion studies inform receptor usage by virulent hantaviruses in human endothelial cells. elife. 2021;10: pubmed publisher
  6. Li D, Peng J, Li T, Liu Y, Chen M, Shi X. Itgb3-integrin-deficient mice may not be a sufficient model for patients with Glanzmann thrombasthenia. Mol Med Rep. 2021;23: pubmed publisher
  7. Park M, Kim A, Manandhar S, Oh S, Jang G, Kang L, et al. CCN1 interlinks integrin and hippo pathway to autoregulate tip cell activity. elife. 2019;8: pubmed publisher
  8. Menon V, Thomas R, Elgueta C, Horl M, Osborn T, Hallett P, et al. Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells. Stem Cells. 2019;37:1293-1306 pubmed publisher
  9. Li Y, Li K, Hu W, Ojcius D, Fang J, Li S, et al. Endocytic recycling and vesicular transport systems mediate transcytosis of Leptospira interrogans across cell monolayer. elife. 2019;8: pubmed publisher
  10. Chu J, Mccormick B, Mazelyte G, Michael M, Vermeren S. HoxB8 neutrophils replicate Fcγ receptor and integrin-induced neutrophil signaling and functions. J Leukoc Biol. 2019;105:93-100 pubmed publisher
  11. Abe A, Hashimoto K, Akiyama A, Iida M, Ikeda N, Hamano A, et al. αvβ5 integrin mediates the effect of vitronectin on the initial stage of differentiation in mouse cerebellar granule cell precursors. Brain Res. 2018;1691:94-104 pubmed publisher
  12. Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, et al. Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation. Nat Commun. 2018;9:1523 pubmed publisher
  13. Harly C, Cam M, Kaye J, Bhandoola A. Development and differentiation of early innate lymphoid progenitors. J Exp Med. 2018;215:249-262 pubmed publisher
  14. den Hartog G, van Osch T, Vos M, Meijer B, Savelkoul H, van Neerven R, et al. BAFF augments IgA2 and IL-10 production by TLR7/8 stimulated total peripheral blood B cells. Eur J Immunol. 2018;48:283-292 pubmed publisher
  15. Kojima M, Gimenes Júnior J, Chan T, Eliceiri B, Baird A, Costantini T, et al. Exosomes in postshock mesenteric lymph are key mediators of acute lung injury triggering the macrophage activation via Toll-like receptor 4. FASEB J. 2018;32:97-110 pubmed publisher
  16. Bae S, Lee M, Mun S, Giannopoulou E, Yong Gonzalez V, Cross J, et al. MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERR?. J Clin Invest. 2017;127:2555-2568 pubmed publisher
  17. Wang L, Luo J, Li B, Tian X, Chen L, Huang Y, et al. Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow. Nature. 2016;540:579-582 pubmed publisher
  18. Jiang M, Qiu J, Zhang L, Lu D, Long M, Chen L, et al. Changes in tension regulates proliferation and migration of fibroblasts by remodeling expression of ECM proteins. Exp Ther Med. 2016;12:1542-1550 pubmed
  19. Ferraro F, Mafalda Lopes da S, GRIMES W, Lee H, Ketteler R, Kriston Vizi J, et al. Weibel-Palade body size modulates the adhesive activity of its von Willebrand Factor cargo in cultured endothelial cells. Sci Rep. 2016;6:32473 pubmed publisher
  20. Liu S, Zhou F, Shen Y, Zhang Y, Yin H, Zeng Y, et al. Fluid shear stress induces epithelial-mesenchymal transition (EMT) in Hep-2 cells. Oncotarget. 2016;7:32876-92 pubmed publisher
  21. Cordeiro O, Chypre M, Brouard N, Rauber S, Alloush F, Romera Hernandez M, et al. Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL. PLoS ONE. 2016;11:e0151848 pubmed publisher
  22. Liu H, Zhang A, Xu J, Chen Y, Zhu Y. H2S protects against fatal myelosuppression by promoting the generation of megakaryocytes/platelets. J Hematol Oncol. 2016;9:13 pubmed publisher
  23. Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed publisher
  24. Murakami K, Günesdogan U, Zylicz J, Tang W, Sengupta R, Kobayashi T, et al. NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers. Nature. 2016;529:403-407 pubmed publisher
  25. Oudart J, Doué M, Vautrin A, Brassart B, Sellier C, Dupont Deshorgue A, et al. The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction. Oncotarget. 2016;7:1516-28 pubmed publisher
  26. Fiore V, Strane P, Bryksin A, White E, Hagood J, Barker T. Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction. J Cell Biol. 2015;211:173-90 pubmed publisher
  27. Mori S, Kodaira M, Ito A, Okazaki M, Kawaguchi N, Hamada Y, et al. Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial Cells. PLoS ONE. 2015;10:e0137486 pubmed publisher
  28. Qiao J, Qi K, Chu P, Mi H, Yang N, Yao H, et al. Infusion of endothelial progenitor cells ameliorates liver injury in mice after haematopoietic stem cell transplantation. Liver Int. 2015;35:2611-20 pubmed publisher
  29. Lujan E, Zunder E, Ng Y, Goronzy I, Nolan G, Wernig M. Early reprogramming regulators identified by prospective isolation and mass cytometry. Nature. 2015;521:352-6 pubmed publisher
  30. Shen Y, Gao M, Ma Y, Yu H, Cui F, Gregersen H, et al. Effect of surface chemistry on the integrin induced pathway in regulating vascular endothelial cells migration. Colloids Surf B Biointerfaces. 2015;126:188-97 pubmed publisher
  31. Inaba J, McConnell E, Davis K. Lunasin sensitivity in non-small cell lung cancer cells is linked to suppression of integrin signaling and changes in histone acetylation. Int J Mol Sci. 2014;15:23705-24 pubmed publisher
  32. Cao Y, Slaney C, Bidwell B, Parker B, Johnstone C, Rautela J, et al. BMP4 inhibits breast cancer metastasis by blocking myeloid-derived suppressor cell activity. Cancer Res. 2014;74:5091-102 pubmed publisher
  33. Cheshenko N, Trepanier J, González P, Eugenin E, Jacobs W, Herold B. Herpes simplex virus type 2 glycoprotein H interacts with integrin ?v?3 to facilitate viral entry and calcium signaling in human genital tract epithelial cells. J Virol. 2014;88:10026-38 pubmed publisher
  34. Zou M, Cao J, Liu Z, Huh S, Polyak K, Yan Q. Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes. J Biol Chem. 2014;289:17620-33 pubmed publisher
  35. Ahn E, Kim Y, Kshitiz -, An S, Afzal J, Lee S, et al. Spatial control of adult stem cell fate using nanotopographic cues. Biomaterials. 2014;35:2401-2410 pubmed publisher
  36. Erlandsson M, Svensson M, Jonsson I, Bian L, Ambartsumian N, Andersson S, et al. Expression of metastasin S100A4 is essential for bone resorption and regulates osteoclast function. Biochim Biophys Acta. 2013;1833:2653-2663 pubmed publisher
  37. Maddala R, Chauhan B, Walker C, Zheng Y, Robinson M, Lang R, et al. Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival. Dev Biol. 2011;360:30-43 pubmed publisher