This is a Validated Antibody Database (VAD) review about mouse Irf4, based on 26 published articles (read how Labome selects the articles), using Irf4 antibody in all methods. It is aimed to help Labome visitors find the most suited Irf4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Irf4 synonym: AI385587; IRF-4; LSIRF; NF-EM5; Spip

Invitrogen
rat monoclonal (3E4)
  • flow cytometry; mouse; 1:200; loading ...; fig 3b
Invitrogen Irf4 antibody (Ebioscience, 3E4) was used in flow cytometry on mouse samples at 1:200 (fig 3b). elife (2020) ncbi
rat monoclonal (3E4)
  • flow cytometry; mouse; loading ...; fig 1g
Invitrogen Irf4 antibody (ThermoFisher, 3E4) was used in flow cytometry on mouse samples (fig 1g). Blood Adv (2020) ncbi
rat monoclonal (3E4)
  • flow cytometry; mouse; 1:200; loading ...; fig 1h
Invitrogen Irf4 antibody (eBioscience, 46-9858-80) was used in flow cytometry on mouse samples at 1:200 (fig 1h). elife (2020) ncbi
rat monoclonal (3E4)
  • flow cytometry; mouse; 1:2000; loading ...; fig 7e
Invitrogen Irf4 antibody (eBioscience, 3E4) was used in flow cytometry on mouse samples at 1:2000 (fig 7e). elife (2019) ncbi
rat monoclonal (3E4)
  • flow cytometry; mouse; 1:300; loading ...; fig 2a
Invitrogen Irf4 antibody (ThermoFisher, 12-9858-80) was used in flow cytometry on mouse samples at 1:300 (fig 2a). Nat Commun (2019) ncbi
rat monoclonal (3E4)
  • flow cytometry; mouse; fig 3g
In order to study the involvement of RANKL in decidual M2 macrophage polarization, Invitrogen Irf4 antibody (ebioscience, 25-9858) was used in flow cytometry on mouse samples (fig 3g). Cell Death Dis (2017) ncbi
rat monoclonal (3E4)
  • flow cytometry; mouse; loading ...
In order to study the regulatory mechanism for the sex-dependent stroke mortality, Invitrogen Irf4 antibody (eBioscience, 3E4) was used in flow cytometry on mouse samples . Cell Immunol (2017) ncbi
rat monoclonal (3E4)
  • flow cytometry; human; loading ...; fig s14c
In order to map the lineage of human dendritic cells, Invitrogen Irf4 antibody (eBiosciences, 3E4) was used in flow cytometry on human samples (fig s14c). Science (2017) ncbi
rat monoclonal (3E4)
  • flow cytometry; mouse; loading ...; fig 3a
Invitrogen Irf4 antibody (eBioscience, 3E4) was used in flow cytometry on mouse samples (fig 3a). Immunology (2017) ncbi
rat monoclonal (3E4)
  • flow cytometry; human; loading ...; fig st12
In order to identify new types of human blood dendritic cells, monocytes, and progenitors through single-cell RNA-seq, Invitrogen Irf4 antibody (eBioscience, 3E4) was used in flow cytometry on human samples (fig st12). Science (2017) ncbi
rat monoclonal (3E4)
  • flow cytometry; mouse; loading ...
In order to demonstrate that DNMT3a directs early CD8 positive T-cell effector and memory fate decisions, Invitrogen Irf4 antibody (eBioscience, 3E4) was used in flow cytometry on mouse samples . Proc Natl Acad Sci U S A (2016) ncbi
rat monoclonal (3E4)
  • flow cytometry; mouse; loading ...; fig 2g
In order to propose that the ERK-AP-1 axis is important for translating TCR signal strength into proportional activation of downstream events, Invitrogen Irf4 antibody (eBiosciences, 46-9858-80) was used in flow cytometry on mouse samples (fig 2g). elife (2016) ncbi
rat monoclonal (3E4)
  • flow cytometry; mouse; fig s5
In order to show that the PTEN-mTORC2 axis maintains T regulatory cell stability and coordinates their control of effector responses, Invitrogen Irf4 antibody (eBioscience, 3E4) was used in flow cytometry on mouse samples (fig s5). Nat Immunol (2015) ncbi
rat monoclonal (3E4)
  • flow cytometry; mouse; 1:200
Invitrogen Irf4 antibody (eBiosciences, 3E4) was used in flow cytometry on mouse samples at 1:200. Cancer Res (2014) ncbi
rat monoclonal (3E4)
  • flow cytometry; rhesus macaque
Invitrogen Irf4 antibody (eBioscience, 3E4) was used in flow cytometry on rhesus macaque samples . Clin Immunol (2014) ncbi
BioLegend
rat monoclonal (IRF4.3E4)
  • flow cytometry; human; loading ...; fig 4
  • flow cytometry; mouse; fig 4i
BioLegend Irf4 antibody (BioLegend, IRF4.3F4) was used in flow cytometry on human samples (fig 4) and in flow cytometry on mouse samples (fig 4i). Aging Cell (2021) ncbi
rat monoclonal (IRF4.3E4)
  • flow cytometry; mouse; loading ...; fig 4b
  • flow cytometry; human; loading ...; fig 4b
BioLegend Irf4 antibody (Biolegend, 646404) was used in flow cytometry on mouse samples (fig 4b) and in flow cytometry on human samples (fig 4b). Cell Rep (2019) ncbi
rat monoclonal (IRF4.3E4)
  • flow cytometry; human; 1:600; loading ...; fig 1f
BioLegend Irf4 antibody (Biolegend, 646403) was used in flow cytometry on human samples at 1:600 (fig 1f). elife (2019) ncbi
rat monoclonal (IRF4.3E4)
  • flow cytometry; mouse; 1:400; loading ...; fig ex2c
BioLegend Irf4 antibody (BioLegend, IRF4.3E4) was used in flow cytometry on mouse samples at 1:400 (fig ex2c). Nat Med (2019) ncbi
rat monoclonal (IRF4.3E4)
  • flow cytometry; mouse; loading ...; fig 8d
BioLegend Irf4 antibody (BioLegend, IRF4.3E4) was used in flow cytometry on mouse samples (fig 8d). Nat Commun (2018) ncbi
rat monoclonal (IRF4.3E4)
  • flow cytometry; mouse; loading ...; fig s9f
In order to investigate the similarity between interferon gamma-induced tumor ischemia and physiological blood vessel regression, BioLegend Irf4 antibody (BioLegend, 646408) was used in flow cytometry on mouse samples (fig s9f). Nature (2017) ncbi
rat monoclonal (IRF4.3E4)
  • flow cytometry; human; fig 7e
In order to assess the effects of lenalidomide on normal human plasma cell generation, BioLegend Irf4 antibody (BioLegend, IRF4.3E4) was used in flow cytometry on human samples (fig 7e). Oncotarget (2016) ncbi
rat monoclonal (IRF4.3E4)
  • flow cytometry; mouse; loading ...; fig 3a
  • immunocytochemistry; mouse; loading ...; fig 2e
In order to study the effect of atypical protein kinase C i on asymmetric division and CD8(+) T Lymphocyte, BioLegend Irf4 antibody (Biolegend, IRF4.3E4) was used in flow cytometry on mouse samples (fig 3a) and in immunocytochemistry on mouse samples (fig 2e). Sci Rep (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (E-7)
  • chromatin immunoprecipitation; human; fig 3
Santa Cruz Biotechnology Irf4 antibody (Santa Cruz, sc-377383) was used in chromatin immunoprecipitation on human samples (fig 3). Ann Rheum Dis (2016) ncbi
rat monoclonal (3E4)
  • flow cytometry; mouse; fig 5
Santa Cruz Biotechnology Irf4 antibody (Santa Cruz Biotechnology, sc-130921) was used in flow cytometry on mouse samples (fig 5). Reprod Fertil Dev (2015) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; fig 5
In order to determine a therapeutic strategy to target the IRF4 network in multiple myeloma by using the bromodomain inhibition of the transcriptional coactivators CBP/EP300, Cell Signaling Technology Irf4 antibody (Cell Signaling Technology, 4948) was used in western blot on human samples (fig 5). elife (2016) ncbi
Articles Reviewed
  1. Webb L, Fra Bido S, Innocentin S, Matheson L, Attaf N, Bignon A, et al. Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ. Aging Cell. 2021;20:e13295 pubmed publisher
  2. Xu A, Barbosa R, Calado D. Genetic timestamping of plasma cells in vivo reveals tissue-specific homeostatic population turnover. elife. 2020;9: pubmed publisher
  3. Witalis M, Chang J, Zhong M, Bouklouch Y, Panneton V, Li J, et al. Progression of AITL-like tumors in mice is driven by Tfh signature proteins and T-B cross talk. Blood Adv. 2020;4:868-879 pubmed publisher
  4. Lee J, Zhang J, Chung Y, Kim J, Kook C, Gonzalez Navajas J, et al. Inhibition of IRF4 in dendritic cells by PRR-independent and -dependent signals inhibit Th2 and promote Th17 responses. elife. 2020;9: pubmed publisher
  5. Leylek R, Alcántara Hernández M, Lanzar Z, Lüdtke A, Perez O, Reizis B, et al. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019;29:3736-3750.e8 pubmed publisher
  6. Koike T, Harada K, Horiuchi S, Kitamura D. The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets. elife. 2019;8: pubmed publisher
  7. Zumaquero E, Stone S, Scharer C, Jenks S, Nellore A, Mousseau B, et al. IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation. elife. 2019;8: pubmed publisher
  8. Hammerich L, Marron T, Upadhyay R, Svensson Arvelund J, Dhainaut M, Hussein S, et al. Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination. Nat Med. 2019;25:814-824 pubmed publisher
  9. Zhu H, Bhatt B, Sivaprakasam S, Cai Y, Liu S, Kodeboyina S, et al. Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR. Nat Commun. 2019;10:1084 pubmed publisher
  10. Li F, Zeng Z, Xing S, Gullicksrud J, Shan Q, Choi J, et al. Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf. Nat Commun. 2018;9:5452 pubmed publisher
  11. Meng Y, Zhou W, Jin L, Liu L, Chang K, Mei J, et al. RANKL-mediated harmonious dialogue between fetus and mother guarantees smooth gestation by inducing decidual M2 macrophage polarization. Cell Death Dis. 2017;8:e3105 pubmed publisher
  12. Seifert H, Benedek G, Liang J, Nguyen H, Kent G, Vandenbark A, et al. Sex differences in regulatory cells in experimental stroke. Cell Immunol. 2017;318:49-54 pubmed publisher
  13. See P, Dutertre C, Chen J, Günther P, McGovern N, Irac S, et al. Mapping the human DC lineage through the integration of high-dimensional techniques. Science. 2017;356: pubmed publisher
  14. Kammertoens T, Friese C, Arina A, Idel C, Briesemeister D, Rothe M, et al. Tumour ischaemia by interferon-? resembles physiological blood vessel regression. Nature. 2017;545:98-102 pubmed publisher
  15. Meinicke H, Bremser A, Brack M, Akeus P, Pearson C, Bullers S, et al. Tumour-associated changes in intestinal epithelial cells cause local accumulation of KLRG1+ GATA3+ regulatory T cells in mice. Immunology. 2017;152:74-88 pubmed publisher
  16. Villani A, Satija R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, et al. Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. Science. 2017;356: pubmed publisher
  17. Ladle B, Li K, Phillips M, Pucsek A, Haile A, Powell J, et al. De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation. Proc Natl Acad Sci U S A. 2016;113:10631-6 pubmed publisher
  18. Allison K, Sajti E, Collier J, Gosselin D, Troutman T, Stone E, et al. Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells. elife. 2016;5: pubmed publisher
  19. Jourdan M, Cren M, Schafer P, Robert N, Duperray C, Vincent L, et al. Differential effects of lenalidomide during plasma cell differentiation. Oncotarget. 2016;7:28096-111 pubmed publisher
  20. Metz P, Lopez J, Kim S, Akimoto K, Ohno S, Chang J. Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8(+) T Lymphocyte Fates. Sci Rep. 2016;6:19182 pubmed publisher
  21. Conery A, Centore R, Neiss A, Keller P, Joshi S, Spillane K, et al. Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma. elife. 2016;5: pubmed publisher
  22. Vecellio M, Roberts A, Cohen C, Cortes A, Knight J, Bowness P, et al. The genetic association of RUNX3 with ankylosing spondylitis can be explained by allele-specific effects on IRF4 recruitment that alter gene expression. Ann Rheum Dis. 2016;75:1534-40 pubmed publisher
  23. Wang J, Yin T, Wen Y, Tian F, He X, Zhou D, et al. Potential effects of interferon regulatory factor 4 in a murine model of polyinosinic-polycytidylic acid-induced embryo resorption. Reprod Fertil Dev. 2015;: pubmed publisher
  24. Shrestha S, Yang K, Guy C, Vogel P, Neale G, Chi H. Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. Nat Immunol. 2015;16:178-87 pubmed publisher
  25. Chatterjee S, Thyagarajan K, Kesarwani P, Song J, Soloshchenko M, Fu J, et al. Reducing CD73 expression by IL1?-Programmed Th17 cells improves immunotherapeutic control of tumors. Cancer Res. 2014;74:6048-59 pubmed publisher
  26. Demberg T, Mohanram V, Venzon D, Robert Guroff M. Phenotypes and distribution of mucosal memory B-cell populations in the SIV/SHIV rhesus macaque model. Clin Immunol. 2014;153:264-76 pubmed publisher