mouse Irf3 antibody | antibody review based on formal publications

This is a Validated Antibody Database (VAD) review about mouse Irf3, based on 134 published articles (read how Labome selects the articles), using Irf3 antibody in all methods. It is aimed to help Labome visitors find the most suited Irf3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.

Irf3 synonym: C920001K05Rik; IRF-3

Knockout validation

Santa Cruz Biotechnology mouse monoclonal (D-3) sc-376455	western blot knockout validation; human; 1:1000; loading ...; fig 3a	Santa Cruz Biotechnology Irf3 antibody (Santa, sc-376455) was used in western blot knockout validation on human samples at 1:1000 (fig 3a). Viruses (2019) ncbi
Cell Signaling Technology domestic rabbit monoclonal (D83B9) 4302	western blot knockout validation; human; fig 3a	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot knockout validation on human samples (fig 3a). MBio (2019) ncbi

Santa Cruz Biotechnology

mouse monoclonal (SL-12) sc-33641	western blot; human; loading ...; fig 4b	Santa Cruz Biotechnology Irf3 antibody (Santa Cruz, sc-33641) was used in western blot on human samples (fig 4b). Pathol Oncol Res (2022) ncbi
mouse monoclonal (D-3) sc-376455	western blot knockout validation; human; 1:1000; loading ...; fig 3a	Santa Cruz Biotechnology Irf3 antibody (Santa, sc-376455) was used in western blot knockout validation on human samples at 1:1000 (fig 3a). Viruses (2019) ncbi
mouse monoclonal (SL-12) sc-33641	western blot; human; 1:1000; fig s5	Santa Cruz Biotechnology Irf3 antibody (Santa Cruz, sc-33641) was used in western blot on human samples at 1:1000 (fig s5). Nat Commun (2016) ncbi
mouse monoclonal (D-3) sc-376455	immunocytochemistry; mouse; fig 5	In order to study the relationship between aging and neomycin-induced deafness due to expression of NLRX1 in C57BL/6 mice cochlear hair cells, Santa Cruz Biotechnology Irf3 antibody (Santa Cruz, sc-3764552) was used in immunocytochemistry on mouse samples (fig 5). Neurosci Lett (2016) ncbi
mouse monoclonal (D-3) sc-376455 sc-376455 X	western blot; mouse; fig 2	Santa Cruz Biotechnology Irf3 antibody (Santa Cruz Biotechnology, D-3) was used in western blot on mouse samples (fig 2). Nat Immunol (2016) ncbi
mouse monoclonal (SL-12) sc-33641	western blot; human; 1:2000	Santa Cruz Biotechnology Irf3 antibody (Santa Cruz, Sc-33641) was used in western blot on human samples at 1:2000. J Virol (2014) ncbi

Abcam

domestic rabbit monoclonal (EPR2418Y) ab68481	western blot; human; loading ...; fig 5e immunohistochemistry - paraffin section; mouse; loading ...; fig 5h	Abcam Irf3 antibody (Abcam, ab68481) was used in western blot on human samples (fig 5e) and in immunohistochemistry - paraffin section on mouse samples (fig 5h). PLoS Pathog (2022) ncbi
domestic rabbit monoclonal (EPR2418Y) ab68481	western blot; human; loading ...; fig 2a	Abcam Irf3 antibody (Abcam, ab68481) was used in western blot on human samples (fig 2a). Cell (2019) ncbi
domestic rabbit monoclonal (EPR2418Y) ab68481	western blot; human; loading ...; fig 7a	Abcam Irf3 antibody (Abcam, ab68481) was used in western blot on human samples (fig 7a). PLoS Pathog (2019) ncbi
domestic rabbit monoclonal (EPR2418Y) ab68481	western blot; human; loading ...; fig 1a	Abcam Irf3 antibody (Abcam, ab68481) was used in western blot on human samples (fig 1a). Cell (2019) ncbi
domestic rabbit monoclonal (EPR2418Y) ab68481	immunocytochemistry; human; loading ...; fig 4a western blot; human; loading ...; fig 4b	Abcam Irf3 antibody (Abcam, ab68481) was used in immunocytochemistry on human samples (fig 4a) and in western blot on human samples (fig 4b). J Autoimmun (2018) ncbi
domestic rabbit monoclonal (EPR2418Y) ab68481	flow cytometry; human; loading ...; fig 2a	Abcam Irf3 antibody (Abcam, ab68481) was used in flow cytometry on human samples (fig 2a). Methods Mol Biol (2018) ncbi
domestic rabbit monoclonal (EPR2418Y) ab68481	western blot; human; loading ...; fig 4c	Abcam Irf3 antibody (Abcam, ab68481) was used in western blot on human samples (fig 4c). J Virol (2017) ncbi

Invitrogen

domestic rabbit polyclonal PA5-36775	western blot; mouse; 1:500; loading ...; fig 4b, s12a	Invitrogen Irf3 antibody (ThermoFisher, PA5-36775) was used in western blot on mouse samples at 1:500 (fig 4b, s12a). Nat Commun (2020) ncbi
domestic rabbit monoclonal (E.875.8) MA5-14947	western blot; human; 1:1000; fig s1	In order to investigate regulatory mechanisms of MAVS activity, Invitrogen Irf3 antibody (Pierce, 5?C14917) was used in western blot on human samples at 1:1000 (fig s1). Nat Commun (2015) ncbi

Cell Signaling Technology

domestic rabbit monoclonal (D83B9) 4302	western blot; human; 1:1000; loading ...	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on human samples at 1:1000. Nat Commun (2022) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 3b	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947S) was used in western blot on mouse samples (fig 3b). J Immunother Cancer (2022) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 3b	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302S) was used in western blot on mouse samples (fig 3b). J Immunother Cancer (2022) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; fig 5e	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on mouse samples (fig 5e). iScience (2022) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 2k	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 2k). iScience (2022) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:200; loading ...; fig 4i	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:200 (fig 4i). PLoS Pathog (2021) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; 1:400; loading ...; fig 4i	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples at 1:400 (fig 4i). PLoS Pathog (2021) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; pigs ; loading ...; fig 1i	Cell Signaling Technology Irf3 antibody (CST, 4947) was used in western blot on pigs samples (fig 1i). PLoS Pathog (2021) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; pigs ; loading ...; fig 1i	Cell Signaling Technology Irf3 antibody (CST, 4302) was used in western blot on pigs samples (fig 1i). PLoS Pathog (2021) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 3c western blot; human; loading ...; fig 3a	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on mouse samples (fig 3c) and in western blot on human samples (fig 3a). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; loading ...; fig 1d	Cell Signaling Technology Irf3 antibody (Cell Signalling, 4302) was used in western blot on human samples (fig 1d). Cancers (Basel) (2021) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; 1:500; loading ...; fig 1i	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947S) was used in western blot on human samples at 1:500 (fig 1i). Cell Rep (2021) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 5g	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on mouse samples (fig 5g). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 2g	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947S) was used in western blot on mouse samples (fig 2g). Cell Rep (2021) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 2g	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302S) was used in western blot on mouse samples (fig 2g). Cell Rep (2021) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 5h	Cell Signaling Technology Irf3 antibody (CST, 4947) was used in western blot on mouse samples (fig 5h). J Nutr Biochem (2021) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 5h	Cell Signaling Technology Irf3 antibody (CST, 4302) was used in western blot on mouse samples (fig 5h). J Nutr Biochem (2021) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; 1:2000	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on human samples at 1:2000. Cell Syst (2021) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; 1:2000	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples at 1:2000. Cell Syst (2021) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; 1:1000; loading ...	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples at 1:1000. Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; 1:1000; loading ...	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on human samples at 1:1000. Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 3f	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 3f). Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 3f	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig 3f). Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (4D4G) 4947		Cell Signaling Technology Irf3 antibody (Cell Signaling Technologies, 4947) was used . Cell Death Discov (2021) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 3h	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302S) was used in western blot on mouse samples (fig 3h). Cancer Res (2021) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; 1:1000; loading ...; fig 4a	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302S) was used in western blot on mouse samples at 1:1000 (fig 4a). elife (2020) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:1000; loading ...; fig 4a	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947S) was used in western blot on mouse samples at 1:1000 (fig 4a). elife (2020) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:1000; loading ...; fig 8b	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on mouse samples at 1:1000 (fig 8b). Nat Commun (2020) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:2000; loading ...; fig 3f western blot; human; 1:2000; loading ...; fig 1i, 2c	Cell Signaling Technology Irf3 antibody (CST, 4947) was used in western blot on mouse samples at 1:2000 (fig 3f) and in western blot on human samples at 1:2000 (fig 1i, 2c). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 1d, 4b western blot; human; loading ...; fig 1d	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302S) was used in western blot on mouse samples (fig 1d, 4b) and in western blot on human samples (fig 1d). J Immunother Cancer (2020) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; 1:1000; fig 4d	Cell Signaling Technology Irf3 antibody (CST, 4302) was used in western blot on mouse samples at 1:1000 (fig 4d). MBio (2020) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:1000; loading ...; fig 2h	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:1000 (fig 2h). elife (2020) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; 1:1000; loading ...; fig 2h	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples at 1:1000 (fig 2h). elife (2020) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 4a	Cell Signaling Technology Irf3 antibody (CST, 4947) was used in western blot on human samples (fig 4a). Biomed Pharmacother (2020) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; loading ...; fig 4c	Cell Signaling Technology Irf3 antibody (CST, 4302) was used in western blot on human samples (fig 4c). Biomed Pharmacother (2020) ncbi
domestic rabbit monoclonal (4D4G) 4947	proximity ligation assay; human; 1:1000; loading ...; fig 3a	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4D4G) was used in proximity ligation assay on human samples at 1:1000 (fig 3a). Nature (2019) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig s4f	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947S) was used in western blot on mouse samples (fig s4f). Science (2019) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig s4f	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302S) was used in western blot on mouse samples (fig s4f). Science (2019) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples . PLoS Pathog (2019) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 2c	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples (fig 2c). Cell (2019) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 2f	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 2f). J Immunol (2019) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 4f	Cell Signaling Technology Irf3 antibody (Cell Signaling Technologies, 4302) was used in western blot on mouse samples (fig 4f). Cell (2019) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 2c	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 2c). Cell (2019) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 7d	Cell Signaling Technology Irf3 antibody (Cell Signaling, D83B9) was used in western blot on mouse samples (fig 7d). J Exp Med (2019) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; 1:1000; loading ...; fig 1b	Cell Signaling Technology Irf3 antibody (Cell signaling, 4302) was used in western blot on human samples at 1:1000 (fig 1b). Nature (2019) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 5f	Cell Signaling Technology Irf3 antibody (CST, 4947) was used in western blot on human samples (fig 5f). Cell (2019) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; loading ...; fig 5f	Cell Signaling Technology Irf3 antibody (CST, 4302) was used in western blot on human samples (fig 5f). Cell (2019) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 7a	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4D4G) was used in western blot on human samples (fig 7a). PLoS Pathog (2019) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 5b	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947S) was used in western blot on human samples (fig 5b). Front Immunol (2019) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 3d	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947s) was used in western blot on mouse samples (fig 3d). Cell (2019) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 3d	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig 3d). Cell (2019) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:1000; loading ...; fig 3a, 3c, s3d	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:1000 (fig 3a, 3c, s3d). Sci Adv (2019) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 3e	Cell Signaling Technology Irf3 antibody (CST, 4947) was used in western blot on human samples (fig 3e). Cell Death Dis (2019) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 6c	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on mouse samples (fig 6c). Immunity (2019) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot knockout validation; human; fig 3a	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot knockout validation on human samples (fig 3a). MBio (2019) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 2d	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302S) was used in western blot on mouse samples (fig 2d). Nat Immunol (2019) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; 1:1000; loading ...; fig 7a western blot; human; 1:1000; loading ...; fig 5a	Cell Signaling Technology Irf3 antibody (CST, D83B9) was used in western blot on mouse samples at 1:1000 (fig 7a) and in western blot on human samples at 1:1000 (fig 5a). Front Immunol (2018) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 1a	Cell Signaling Technology Irf3 antibody (Biosciences, 4302) was used in western blot on mouse samples (fig 1a). Cell Death Differ (2018) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 1a	Cell Signaling Technology Irf3 antibody (Biosciences, 4947) was used in western blot on mouse samples (fig 1a). Cell Death Differ (2018) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; 1:500; loading ...; fig 2d, 2l western blot; mouse; 1:500; loading ...; fig 1p, 5g, 6f	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4D4G) was used in western blot on human samples at 1:500 (fig 2d, 2l) and in western blot on mouse samples at 1:500 (fig 1p, 5g, 6f). Nat Commun (2018) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; 1:1000; loading ...; fig 2d, 2l western blot; mouse; 1:1000; loading ...; fig 1p, 5g, 6f	Cell Signaling Technology Irf3 antibody (Cell Signaling, D83B9) was used in western blot on human samples at 1:1000 (fig 2d, 2l) and in western blot on mouse samples at 1:1000 (fig 1p, 5g, 6f). Nat Commun (2018) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 4b	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 4b). J Virol (2018) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:1000; loading ...; fig s4a	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:1000 (fig s4a). Nat Commun (2018) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; fig 4d	Cell Signaling Technology Irf3 antibody ((Cell Signaling Technology, 4947) was used in western blot on mouse samples (fig 4d). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; fig 4d	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on mouse samples (fig 4d). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:500; loading ...; fig 4b	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:500 (fig 4b). Nat Commun (2018) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 5f	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 5f). J Immunol (2018) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; loading ...; fig 5f	Cell Signaling Technology Irf3 antibody (Cell Signaling, D83B9) was used in western blot on human samples (fig 5f). J Immunol (2018) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 9d	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 9d). J Cell Biol (2018) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 5b	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples (fig 5b). Cell (2017) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 6d	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 6d). Immunity (2017) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 2c	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig 2c). Proc Natl Acad Sci U S A (2017) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig s17c	In order to study the effects of interleukin-10 on macrophages and inflammation, Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig s17c). Science (2017) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:5000; loading ...; fig 3a	In order to describe the mechanism by which FBXW7 stabilizes RigI, Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:5000 (fig 3a). Nat Commun (2017) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:1000; loading ...; fig 3a	In order to analyze the effects of dopamine related metabolite concentrations in M1 and M2 microglia phenotypes, Cell Signaling Technology Irf3 antibody (Cell Signaling, 4,947) was used in western blot on mouse samples at 1:1000 (fig 3a). Front Cell Neurosci (2017) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; 1:1000; loading ...; fig 7b	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4D4G) was used in western blot on human samples at 1:1000 (fig 7b). Nat Commun (2017) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 2b western blot; mouse; loading ...; fig 2a, 3a	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 2b) and in western blot on mouse samples (fig 2a, 3a). J Biol Chem (2017) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; loading ...; fig 2b western blot; mouse; loading ...; fig 2a, 3a	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on human samples (fig 2b) and in western blot on mouse samples (fig 2a, 3a). J Biol Chem (2017) ncbi
domestic rabbit monoclonal (D83B9) 4302	immunohistochemistry; human; loading ...; fig 5e	In order to find interferon-gamma inducible factor 16 functions in the cyclic GMP-AMP synthase-stimulator of interferon genes pathway, Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in immunohistochemistry on human samples (fig 5e). Nat Commun (2017) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 2d	In order to find interferon-gamma inducible factor 16 functions in the cyclic GMP-AMP synthase-stimulator of interferon genes pathway, Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947s) was used in western blot on human samples (fig 2d). Nat Commun (2017) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 5A western blot; mouse; loading ...; fig 2A	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 5A) and in western blot on mouse samples (fig 2A). Biochem J (2017) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 5a	In order to describe factors regulating RIG-I/IRF3 signaling activity, Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 5a). Mol Cell (2017) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 4a	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 4a). Nucleic Acids Res (2017) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 4a	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 4a). MBio (2017) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; fig 6 western blot; mouse; fig 6	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on human samples (fig 6) and in western blot on mouse samples (fig 6). Sci Rep (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; fig 6 western blot; human; fig 6	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 6) and in western blot on human samples (fig 6). Sci Rep (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 4a	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4D4G) was used in western blot on mouse samples (fig 4a). Immunology (2017) ncbi
domestic rabbit monoclonal (D83B9) 4302	immunocytochemistry; mouse; loading ...; fig 4b western blot; mouse; loading ...; fig 4a	Cell Signaling Technology Irf3 antibody (Cell Signaling, D83B9) was used in immunocytochemistry on mouse samples (fig 4b) and in western blot on mouse samples (fig 4a). Immunology (2017) ncbi
domestic rabbit monoclonal (4D4G) 4947	immunocytochemistry; human; 1:50; loading ...; fig 4f	In order to research the effect of intracellular STING inactivation on the drug sensitivity of breast cancer cells, Cell Signaling Technology Irf3 antibody (Cell signaling, 4947) was used in immunocytochemistry on human samples at 1:50 (fig 4f). Oncotarget (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; fig 4	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 3d	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 3d). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 3d	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig 3d). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:200; loading ...; fig 3f	In order to develop and characterize a murine model of hepatitis A virus, Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:200 (fig 3f). Science (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; Chinese tree shrew; fig 5d	In order to investigate the evolution of RIG-I-like receptors, Cell Signaling Technology Irf3 antibody (Cell signaling, 4302) was used in western blot on Chinese tree shrew samples (fig 5d). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; Chinese tree shrew; fig 5d	In order to investigate the evolution of RIG-I-like receptors, Cell Signaling Technology Irf3 antibody (Cell signaling, 4947) was used in western blot on Chinese tree shrew samples (fig 5d). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 7c	Cell Signaling Technology Irf3 antibody (Cell signaling, 4947) was used in western blot on human samples (fig 7c). J Neuroinflammation (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; 1:5000; fig 5 immunocytochemistry; mouse; 1:500; fig 3 western blot; mouse; 1:5000; fig 5	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302S) was used in western blot on human samples at 1:5000 (fig 5), in immunocytochemistry on mouse samples at 1:500 (fig 3) and in western blot on mouse samples at 1:5000 (fig 5). BMC Biol (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:2000; fig 5 western blot; human; 1:2000; fig 5	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947S) was used in western blot on mouse samples at 1:2000 (fig 5) and in western blot on human samples at 1:2000 (fig 5). BMC Biol (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; fig 6	In order to demonstrate that OTULIN is essential for preventing TNF-associated systemic inflammation in humans and mice, Cell Signaling Technology Irf3 antibody (Cell Signaling Tech, 4947) was used in western blot on mouse samples (fig 6). Cell (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 3d	Cell Signaling Technology Irf3 antibody (Cell Signaling, D83B9) was used in western blot on mouse samples (fig 3d). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 3d	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4D4G) was used in western blot on mouse samples (fig 3d). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; fig 8	Cell Signaling Technology Irf3 antibody (Cell signaling, 4302S) was used in western blot on mouse samples (fig 8). PLoS Pathog (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; fig 8	Cell Signaling Technology Irf3 antibody (Cell signaling, 4947S) was used in western blot on mouse samples (fig 8). PLoS Pathog (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; fig 4c	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 4c). BMC Complement Altern Med (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:1000; loading ...; fig 2e western blot; human; 1:1000; loading ...; fig 1g	In order to explore the anti-viral effects of iRhom2, Cell Signaling Technology Irf3 antibody (Cell Signaling, 4D4G) was used in western blot on mouse samples at 1:1000 (fig 2e) and in western blot on human samples at 1:1000 (fig 1g). Nat Immunol (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig s9	In order to study the impact of p21 signaling on monocyte reprogramming, Cell Signaling Technology Irf3 antibody (cell signalling, 4947) was used in western blot on mouse samples (fig s9). J Clin Invest (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 6c	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4D4G) was used in western blot on mouse samples (fig 6c). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig s2a	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig s2a). J Clin Invest (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; fig 6	In order to utilize CRISPR/Cas9 knock-out cell lines and vaccinia virus mutants to elucidate opposing roles of double-stranded RNA effector pathways and viral defense proteins, Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples (fig 6). J Virol (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:1000; fig 3 western blot; African green monkey; 1:1000; fig 1	In order to learn the requirement of palmitoylation at the Golgi by activation of STING, Cell Signaling Technology Irf3 antibody (Cell Signalling, 4D4G) was used in western blot on mouse samples at 1:1000 (fig 3) and in western blot on African green monkey samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; 1:1000; fig s5	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302S) was used in western blot on human samples at 1:1000 (fig s5). Nat Commun (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; 1:1000; fig s13	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947S) was used in western blot on human samples at 1:1000 (fig s13). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; fig 2a	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig 2a). J Virol (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; fig 1a	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 1a). J Virol (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; 1:1000; fig 1	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:1000; fig 1	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 4a	Cell Signaling Technology Irf3 antibody (Cell signaling, 4947) was used in western blot on mouse samples (fig 4a). elife (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; loading ...; fig 4a	Cell Signaling Technology Irf3 antibody (Cell signaling, 4302) was used in western blot on mouse samples (fig 4a). elife (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; fig 5	In order to characterize promotion of an effective anti-tumor immune response by enhancing the production of type 1 interferons by 2'-5' oligoadenylate synthetase-like 1 (OASL1) deficiency in mice, Cell Signaling Technology Irf3 antibody (Cell signaling, 4302) was used in western blot on mouse samples (fig 5). Cancer Immunol Immunother (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; fig 3 western blot; mouse; fig 3	Cell Signaling Technology Irf3 antibody (Cell Signaling Tech, 4302) was used in western blot on human samples (fig 3) and in western blot on mouse samples (fig 3). Sci Rep (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; fig 3 western blot; human; fig 3	Cell Signaling Technology Irf3 antibody (Cell Signaling Tech, 4947) was used in western blot on mouse samples (fig 3) and in western blot on human samples (fig 3). Sci Rep (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; fig 4	Cell Signaling Technology Irf3 antibody (Cell signaling, 4947S) was used in western blot on human samples (fig 4). Nat Immunol (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; fig 4	Cell Signaling Technology Irf3 antibody (Cell signaling, 4302S) was used in western blot on human samples (fig 4). Nat Immunol (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; loading ...; fig 2b	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947S) was used in western blot on human samples (fig 2b). Cell Res (2016) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; fig s10b	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, D83B9) was used in western blot on human samples (fig s10b). BMC Biotechnol (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; fig s2	Cell Signaling Technology Irf3 antibody (Cell Signaling Tech, 4947S) was used in western blot on human samples (fig s2). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; fig 11	In order to identify small molecules that activate the type I interferon response via IFN regulatory factor 3, Cell Signaling Technology Irf3 antibody (cell Signaling, 4947) was used in western blot on mouse samples (fig 11). PLoS Pathog (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; fig 1	Cell Signaling Technology Irf3 antibody (CST, 4947S) was used in western blot on mouse samples (fig 1). Proc Natl Acad Sci U S A (2015) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; fig 3	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on human samples (fig 3). Proc Natl Acad Sci U S A (2015) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse	In order to study mechanisms that regulate TLR-induced IL-12 expression and the Th1 response, Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on mouse samples . Virol Sin (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; fig 1	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947s) was used in western blot on mouse samples (fig 1). PLoS Pathog (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; fig 4 western blot; mouse; fig 4	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 4) and in western blot on mouse samples (fig 4). Mol Cell Biol (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig S9	In order to generate mathematical models of the host inflammatory response induced by virulent influenza strains, Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig S9). PLoS Pathog (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples . J Virol (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; fig 1	In order to study inhibitors of bromodomain and extra-terminal (BET) family members by suppression of interferon beta gene transcription, Cell Signaling Technology Irf3 antibody (Cell Signaling Technologies, 4947) was used in western blot on mouse samples (fig 1). Biochem J (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:1000; fig s2	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples at 1:1000 (fig s2). Nat Commun (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; fig 4 western blot; human; fig 4	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples (fig 4) and in western blot on human samples (fig 4). PLoS Pathog (2015) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; fig 5 western blot; human; fig 5	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig 5) and in western blot on human samples (fig 5). PLoS Pathog (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; 1:1000; fig 3c	In order to identify gene variants that contribute to amyotrophic lateral sclerosis, Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples at 1:1000 (fig 3c). Nat Neurosci (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; fig 1	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; loading ...; fig 4a	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4D4G) was used in western blot on mouse samples (fig 4a). J Immunol (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; 1:500; loading ...; fig 4	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples at 1:500 (fig 4). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; fig 1	In order to analyze the antiviral innate immune response due to mitochondrial DNA stress, Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, D83B9) was used in western blot on mouse samples (fig 1). Nature (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4D4G) was used in western blot on mouse samples . J Biol Chem (2015) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, D83B9) was used in western blot on mouse samples . J Biol Chem (2015) ncbi
domestic rabbit monoclonal (4D4G) 4947	chromatin immunoprecipitation; human; fig 4	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in chromatin immunoprecipitation on human samples (fig 4). Nucleic Acids Res (2014) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; fig 2	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on human samples (fig 2). Basic Res Cardiol (2014) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; fig 2	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 2). Basic Res Cardiol (2014) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse	In order to study the relationship between adenosine deaminase acting on RNA 1 (ADAR1) and type I IFNs, Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on mouse samples . J Immunol (2014) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples . J Virol (2014) ncbi
domestic rabbit monoclonal (4D4G) 4947	immunohistochemistry - frozen section; mouse; 1:500	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in immunohistochemistry - frozen section on mouse samples at 1:500. J Neurosci Res (2014) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; fig 4f	In order to elucidate type I interferon-independent viral immune responses, Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on human samples (fig 4f). Nat Immunol (2014) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4947) was used in western blot on mouse samples . PLoS Pathog (2014) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; 1:1000	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples at 1:1000. PLoS ONE (2014) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; human; 1:1000	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on human samples at 1:1000. PLoS ONE (2014) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; 1:1,000	In order to study the mechanism for the oncolytic measles virus replication, Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947S) was used in western blot on human samples at 1:1,000. J Virol (2014) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; human; 1:1000	Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4947) was used in western blot on human samples at 1:1000. J Virol (2014) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse; 1:3000	Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples at 1:3000. J Virol (2014) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse; 1:1000	Cell Signaling Technology Irf3 antibody (cst, 4947) was used in western blot on mouse samples at 1:1000. Mol Cell Endocrinol (2013) ncbi
domestic rabbit monoclonal (D83B9) 4302	western blot; mouse	Cell Signaling Technology Irf3 antibody (CST, 4302) was used in western blot on mouse samples . Immunity (2012) ncbi
domestic rabbit monoclonal (4D4G) 4947	western blot; mouse	Cell Signaling Technology Irf3 antibody (CST, 4947) was used in western blot on mouse samples . Immunity (2012) ncbi

Articles Reviewed

Zimmerli D, Brambillasca C, Talens F, Bhin J, Linstra R, Romanens L, et al. MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling. Nat Commun. 2022;13:6579 pubmed publisher
Ni H, Zhang H, Li L, Huang H, Guo H, Zhang L, et al. T cell-intrinsic STING signaling promotes regulatory T cell induction and immunosuppression by upregulating FOXP3 transcription in cervical cancer. J Immunother Cancer. 2022;10: pubmed publisher
Jiang L, Li D, Wang C, Liao J, Liu J, Wei Q, et al. Decreased Expression of Karyopherin-α 1 is Related to the Malignant Degree of Cervical Cancer and is Critical for the Proliferation of Hela Cells. Pathol Oncol Res. 2022;28:1610518 pubmed publisher
Zhao X, Hu S, Zeng L, Liu X, Song Y, Zhang Y, et al. Irradiation combined with PD-L1-/- and autophagy inhibition enhances the antitumor effect of lung cancer via cGAS-STING-mediated T cell activation. iScience. 2022;25:104690 pubmed publisher
Tan H, Yong Y, Xue Y, Liu H, Furihata T, Shankar E, et al. cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model. iScience. 2022;25:104404 pubmed publisher
Ma C, Li Y, Zong Y, Velkov T, Wang C, Yang X, et al. p21 restricts influenza A virus by perturbing the viral polymerase complex and upregulating type I interferon signaling. PLoS Pathog. 2022;18:e1010295 pubmed publisher
Sun L, Li Y, Misumi I, Gonzalez Lopez O, Hensley L, Cullen J, et al. IRF3-mediated pathogenicity in a murine model of human hepatitis A. PLoS Pathog. 2021;17:e1009960 pubmed publisher
Wang Z, Chen J, Wu X, Ma D, Zhang X, Li R, et al. PCV2 targets cGAS to inhibit type I interferon induction to promote other DNA virus infection. PLoS Pathog. 2021;17:e1009940 pubmed publisher
Zhao F, Zheng T, Gong W, Wu J, Xie H, Li W, et al. Extracellular vesicles package dsDNA to aggravate Crohn's disease by activating the STING pathway. Cell Death Dis. 2021;12:815 pubmed publisher
Proctor M, Gonzalez Cruz J, Daignault Mill S, Veitch M, Zeng B, Ehmann A, et al. Targeting Replication Stress Using CHK1 Inhibitor Promotes Innate and NKT Cell Immune Responses and Tumour Regression. Cancers (Basel). 2021;13: pubmed publisher
Bruand M, Barras D, Mina M, Ghisoni E, Morotti M, Lanitis E, et al. Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING. Cell Rep. 2021;36:109412 pubmed publisher
Liu Q, Wu J, Zhang X, Li X, Wu X, Zhao Y, et al. Circulating mitochondrial DNA-triggered autophagy dysfunction via STING underlies sepsis-related acute lung injury. Cell Death Dis. 2021;12:673 pubmed publisher
Shen Y, Tang K, Chen D, Hong M, Sun F, Wang S, et al. Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation. Cell Rep. 2021;35:109272 pubmed publisher
Zhang G, Li R, Li W, Yang S, Sun Q, Yin H, et al. Toll-like receptor 3 ablation prevented high-fat diet-induced obesity and metabolic disorder. J Nutr Biochem. 2021;95:108761 pubmed publisher
Lopacinski A, Sweatt A, Smolko C, Gray Gaillard E, Borgman C, Shah M, et al. Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback. Cell Syst. 2021;12:304-323.e13 pubmed publisher
Guo G, Gao M, Gao X, Zhu B, Huang J, Luo K, et al. SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response. Signal Transduct Target Ther. 2021;6:119 pubmed publisher
Yu Z, Li X, Yang M, Huang J, Fang Q, Jia J, et al. TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO. Signal Transduct Target Ther. 2021;6:90 pubmed publisher
Lee J, Park I, Kwak M, Rhee W, Kim S, Shin J. HMGB1 orchestrates STING-mediated senescence via TRIM30α modulation in cancer cells. Cell Death Discov. 2021;7:28 pubmed publisher
Wang Y, Luo M, Chen Y, Wang Y, Zhang B, Ren Z, et al. ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth. Cancer Res. 2021;81:174-186 pubmed publisher
Tao L, Lemoff A, Wang G, Zarek C, Lowe A, Yan N, et al. Reactive oxygen species oxidize STING and suppress interferon production. elife. 2020;9: pubmed publisher
Kang L, Yu H, Yang X, Zhu Y, Bai X, Wang R, et al. Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke. Nat Commun. 2020;11:2488 pubmed publisher
Deng M, Tam J, Wang L, Liang K, Li S, Zhang L, et al. TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination. Nat Commun. 2020;11:2193 pubmed publisher
von Roemeling C, Wang Y, Qie Y, Yuan H, Zhao H, Liu X, et al. Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity. Nat Commun. 2020;11:1508 pubmed publisher
Wang Bishop L, Wehbe M, Shae D, James J, Hacker B, Garland K, et al. Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma. J Immunother Cancer. 2020;8: pubmed publisher
Ma H, Qian W, Bambousková M, Collins P, Porter S, Byrum A, et al. Barrier-to-Autointegration Factor 1 Protects against a Basal cGAS-STING Response. MBio. 2020;11: pubmed publisher
Weindel C, Bell S, Vail K, West K, Patrick K, Watson R. LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to Mycobacterium tuberculosis. elife. 2020;9: pubmed publisher
Cai H, Yan L, Liu N, Xu M, Cai H. IFI16 promotes cervical cancer progression by upregulating PD-L1 in immunomicroenvironment through STING-TBK1-NF-kB pathway. Biomed Pharmacother. 2020;123:109790 pubmed publisher
Luteijn R, Zaver S, Gowen B, Wyman S, Garelis N, Onia L, et al. SLC19A1 transports immunoreactive cyclic dinucleotides. Nature. 2019;573:434-438 pubmed publisher
Liu Y, You Y, Lu Z, Yang J, Li P, Liu L, et al. N6-methyladenosine RNA modification-mediated cellular metabolism rewiring inhibits viral replication. Science. 2019;365:1171-1176 pubmed publisher
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, et al. Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex. PLoS Pathog. 2019;15:e1008002 pubmed publisher
Zierhut C, Yamaguchi N, Paredes M, Luo J, Carroll T, Funabiki H. The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death. Cell. 2019;178:302-315.e23 pubmed publisher
Xia Z, Xu G, Nie L, Liu L, Peng N, He Q, et al. NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1. J Immunol. 2019;: pubmed publisher
Ergun S, Fernandez D, Weiss T, Li L. STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition. Cell. 2019;: pubmed publisher
Zhang W, Wang G, Xu Z, Tu H, Hu F, Dai J, et al. Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS. Cell. 2019;: pubmed publisher
von Gamm M, Schaub A, Jones A, Wolf C, Behrens G, Lichti J, et al. Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3. J Exp Med. 2019;: pubmed publisher
Zhao B, Du F, Xu P, Shu C, Sankaran B, Bell S, et al. A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1. Nature. 2019;: pubmed publisher
Liu C, Li X, Nan F, Jiang S, Gao X, Guo S, et al. Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity. Cell. 2019;177:865-880.e21 pubmed publisher
Skjesol A, Yurchenko M, Bösl K, Gravastrand C, Nilsen K, Grøvdal L, et al. The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2. PLoS Pathog. 2019;15:e1007684 pubmed publisher
Ashley C, Abendroth A, McSharry B, Slobedman B. Interferon-Independent Upregulation of Interferon-Stimulated Genes during Human Cytomegalovirus Infection is Dependent on IRF3 Expression. Viruses. 2019;11: pubmed publisher
Guan X, Zhang M, Fu M, Luo S, Hu Q. Herpes Simplex Virus Type 2 Immediate Early Protein ICP27 Inhibits IFN-β Production in Mucosal Epithelial Cells by Antagonizing IRF3 Activation. Front Immunol. 2019;10:290 pubmed publisher
Tan Y, Kagan J. Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility. Cell. 2019;: pubmed publisher
Dai J, Huang Y, He X, Zhao M, Wang X, Liu Z, et al. Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity. Cell. 2019;: pubmed publisher
Liu Z, Wu C, Pan Y, Liu H, Wang X, Yang Y, et al. NDR2 promotes the antiviral immune response via facilitating TRIM25-mediated RIG-I activation in macrophages. Sci Adv. 2019;5:eaav0163 pubmed publisher
Majumdar T, Sharma S, Kumar M, Hussain M, Chauhan N, Kalia I, et al. Tryptophan-kynurenine pathway attenuates β-catenin-dependent pro-parasitic role of STING-TICAM2-IRF3-IDO1 signalosome in Toxoplasma gondii infection. Cell Death Dis. 2019;10:161 pubmed publisher
Arora H, Wilcox S, Johnson L, Munro L, Eyford B, Pfeifer C, et al. The ATP-Binding Cassette Gene ABCF1 Functions as an E2 Ubiquitin-Conjugating Enzyme Controlling Macrophage Polarization to Dampen Lethal Septic Shock. Immunity. 2019;50:418-431.e6 pubmed publisher
Botto S, Abraham J, Mizuno N, Pryke K, Gall B, Landais I, et al. Human Cytomegalovirus Immediate Early 86-kDa Protein Blocks Transcription and Induces Degradation of the Immature Interleukin-1β Protein during Virion-Mediated Activation of the AIM2 Inflammasome. MBio. 2019;10: pubmed publisher
Srikanth S, Woo J, Wu B, El Sherbiny Y, Leung J, Chupradit K, et al. The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum. Nat Immunol. 2019;20:152-162 pubmed publisher
Alam M, Yang D, Trivett A, Meyer T, Oppenheim J. HMGN1 and R848 Synergistically Activate Dendritic Cells Using Multiple Signaling Pathways. Front Immunol. 2018;9:2982 pubmed publisher
Liu D, Wu H, Wang C, Li Y, Tian H, Siraj S, et al. STING directly activates autophagy to tune the innate immune response. Cell Death Differ. 2018;: pubmed publisher
Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, et al. STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nat Commun. 2018;9:5226 pubmed publisher
Lu D, Song J, Sun Y, Qi F, Liu L, Jin Y, et al. Mutations of deubiquitinase OTUD1 are associated with autoimmune disorders. J Autoimmun. 2018;94:156-165 pubmed publisher
Qi D, Hu L, Jiao T, Zhang T, Tong X, Ye X. Phosphatase Cdc25A Negatively Regulates the Antiviral Immune Response by Inhibiting TBK1 Activity. J Virol. 2018;92: pubmed publisher
Liu Z, Qin Q, Wu C, Li H, Shou J, Yang Y, et al. Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop. Nat Commun. 2018;9:2789 pubmed publisher
Li F, Li Y, Liang H, Xu T, Kong Y, Huang M, et al. HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infection. J Clin Invest. 2018;128:4148-4162 pubmed publisher
Yang L, Wang L, Ketkar H, Ma J, Yang G, Cui S, et al. UBXN3B positively regulates STING-mediated antiviral immune responses. Nat Commun. 2018;9:2329 pubmed publisher
Ahmad R, Al Roub A, Kochumon S, Akther N, Thomas R, Kumari M, et al. The Synergy between Palmitate and TNF-α for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation. J Immunol. 2018;200:3599-3611 pubmed publisher
Trifonova R, Barteneva N. Quantitation of IRF3 Nuclear Translocation in Heterogeneous Cellular Populations from Cervical Tissue Using Imaging Flow Cytometry. Methods Mol Biol. 2018;1745:125-153 pubmed publisher
Yurchenko M, Skjesol A, Ryan L, Richard G, Kandasamy R, Wang N, et al. SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages. J Cell Biol. 2018;217:1411-1429 pubmed publisher
Gaidt M, Ebert T, Chauhan D, Ramshorn K, Pinci F, Zuber S, et al. The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3. Cell. 2017;171:1110-1124.e18 pubmed publisher
Nguyen T, Smith B, Tate M, Belz G, Barrios M, Elgass K, et al. SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition. Immunity. 2017;47:498-509.e6 pubmed publisher
Kazak L, Chouchani E, Stavrovskaya I, Lu G, Jedrychowski M, Egan D, et al. UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction. Proc Natl Acad Sci U S A. 2017;114:7981-7986 pubmed publisher
Ip W, Hoshi N, Shouval D, Snapper S, Medzhitov R. Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages. Science. 2017;356:513-519 pubmed publisher
Song Y, Lai L, Chong Z, He J, Zhang Y, Xue Y, et al. E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses. Nat Commun. 2017;8:14654 pubmed publisher
Shan M, Lin S, Li S, Du Y, Zhao H, Hong H, et al. TIR-Domain-Containing Adapter-Inducing Interferon-? (TRIF) Is Essential for MPTP-Induced Dopaminergic Neuroprotection via Microglial Cell M1/M2 Modulation. Front Cell Neurosci. 2017;11:35 pubmed publisher
Almine J, O Hare C, Dunphy G, Haga I, Naik R, Atrih A, et al. IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes. Nat Commun. 2017;8:14392 pubmed publisher
Hsia H, Hutti J, Baldwin A. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity. J Biol Chem. 2017;292:5405-5417 pubmed publisher
Jønsson K, Laustsen A, Krapp C, Skipper K, Thavachelvam K, Hotter D, et al. IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP. Nat Commun. 2017;8:14391 pubmed publisher
Bakshi S, Taylor J, Strickson S, McCartney T, Cohen P. Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon ?. Biochem J. 2017;474:1163-1174 pubmed publisher
Hu Y, Li W, Gao T, Cui Y, Jin Y, Li P, et al. The Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Inhibits Type I Interferon Production by Interfering with TRIM25-Mediated RIG-I Ubiquitination. J Virol. 2017;91: pubmed publisher
Willemsen J, Wicht O, Wolanski J, Baur N, Bastian S, Haas D, et al. Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening. Mol Cell. 2017;65:403-415.e8 pubmed publisher
Suspène R, Mussil B, Laude H, Caval V, Berry N, Bouzidi M, et al. Self-cytoplasmic DNA upregulates the mutator enzyme APOBEC3A leading to chromosomal DNA damage. Nucleic Acids Res. 2017;45:3231-3241 pubmed publisher
Cai B, Wu J, Yu X, Su X, Wang R. FOSL1 Inhibits Type I Interferon Responses to Malaria and Viral Infections by Blocking TBK1 and TRAF3/TRIF Interactions. MBio. 2017;8: pubmed publisher
Boro M, Singh V, Balaji K. Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses. Sci Rep. 2016;6:37695 pubmed publisher
Klaska I, Muckersie E, Martin Granados C, Christofi M, Forrester J. Lipopolysaccharide-primed heterotolerant dendritic cells suppress experimental autoimmune uveoretinitis by multiple mechanisms. Immunology. 2017;150:364-377 pubmed publisher
Gaston J, Cheradame L, Yvonnet V, Déas O, Poupon M, Judde J, et al. Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents. Oncotarget. 2016;7:77205-77224 pubmed publisher
Omura H, Oikawa D, Nakane T, Kato M, Ishii R, Ishitani R, et al. Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide. Sci Rep. 2016;6:34756 pubmed publisher
Huai W, Song H, Yu Z, Wang W, Han L, Sakamoto T, et al. Mint3 potentiates TLR3/4- and RIG-I-induced IFN-? expression and antiviral immune responses. Proc Natl Acad Sci U S A. 2016;113:11925-11930 pubmed
Hirai Yuki A, Hensley L, McGivern D, Gonzalez Lopez O, Das A, Feng H, et al. MAVS-dependent host species range and pathogenicity of human hepatitis A virus. Science. 2016;353:1541-1545 pubmed
Xu L, Yu D, Fan Y, Peng L, Wu Y, Yao Y. Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew. Proc Natl Acad Sci U S A. 2016;113:10950-5 pubmed publisher
Zhang X, Zheng Z, Liu X, Shu B, Mao P, Bai B, et al. Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway. J Neuroinflammation. 2016;13:209 pubmed publisher
Pourcelot M, Zemirli N, Silva da Costa L, Loyant R, Garcin D, Vitour D, et al. The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing. BMC Biol. 2016;14:69 pubmed publisher
Damgaard R, Walker J, Marco Casanova P, Morgan N, Titheradge H, Elliott P, et al. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. Cell. 2016;166:1215-1230.e20 pubmed publisher
Wang W, Jiang M, Liu S, Zhang S, Liu W, Ma Y, et al. RNF122 suppresses antiviral type I interferon production by targeting RIG-I CARDs to mediate RIG-I degradation. Proc Natl Acad Sci U S A. 2016;113:9581-6 pubmed publisher
Meliopoulos V, Van De Velde L, Van De Velde N, Karlsson E, Neale G, Vogel P, et al. An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens. PLoS Pathog. 2016;12:e1005804 pubmed publisher
Kim J, Weeratunga P, Kim M, Nikapitiya C, Lee B, Uddin M, et al. Inhibitory effects of an aqueous extract from Cortex Phellodendri on the growth and replication of broad-spectrum of viruses in vitro and in vivo. BMC Complement Altern Med. 2016;16:265 pubmed publisher
Luo W, Li S, Li C, Lian H, Yang Q, Zhong B, et al. iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING. Nat Immunol. 2016;17:1057-66 pubmed publisher
Rackov G, Hernandez Jimenez E, Shokri R, Carmona Rodríguez L, Manes S, Alvarez Mon M, et al. p21 mediates macrophage reprogramming through regulation of p50-p50 NF-?B and IFN-?. J Clin Invest. 2016;126:3089-103 pubmed publisher
Liu C, Yue R, Yang Y, Cui Y, Yang L, Zhao D, et al. AIM2 inhibits autophagy and IFN-? production during M. bovis infection. Oncotarget. 2016;7:46972-46987 pubmed publisher
Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, et al. IRF3 promotes adipose inflammation and insulin resistance and represses browning. J Clin Invest. 2016;126:2839-54 pubmed publisher
Liu R, Moss B. Opposing Roles of Double-Stranded RNA Effector Pathways and Viral Defense Proteins Revealed with CRISPR-Cas9 Knockout Cell Lines and Vaccinia Virus Mutants. J Virol. 2016;90:7864-79 pubmed publisher
Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed publisher
Lin W, Zhang J, Lin H, Li Z, Sun X, Xin D, et al. Syndecan-4 negatively regulates antiviral signalling by mediating RIG-I deubiquitination via CYLD. Nat Commun. 2016;7:11848 pubmed publisher
Anghelina D, Lam E, Falck Pedersen E. Diminished Innate Antiviral Response to Adenovirus Vectors in cGAS/STING-Deficient Mice Minimally Impacts Adaptive Immunity. J Virol. 2016;90:5915-27 pubmed publisher
Uto T, Fukaya T, Takagi H, Arimura K, Nakamura T, Kojima N, et al. Clec4A4 is a regulatory receptor for dendritic cells that impairs inflammation and T-cell immunity. Nat Commun. 2016;7:11273 pubmed publisher
Yu Z, Chen T, Li X, Yang M, Tang S, Zhu X, et al. Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response. elife. 2016;5: pubmed publisher
Sim C, Cho Y, Kim B, Baek I, Kim Y, Lee M. 2'-5' Oligoadenylate synthetase-like 1 (OASL1) deficiency in mice promotes an effective anti-tumor immune response by enhancing the production of type I interferons. Cancer Immunol Immunother. 2016;65:663-75 pubmed publisher
Zhao K, Zhang M, Zhang L, Wang P, Song G, Liu B, et al. Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response. Sci Rep. 2016;6:23771 pubmed publisher
Starokadomskyy P, Gemelli T, Rios J, Xing C, Wang R, Li H, et al. DNA polymerase-? regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol. 2016;17:495-504 pubmed publisher
Qin Y, Liu Q, Tian S, Xie W, Cui J, Wang R. TRIM9 short isoform preferentially promotes DNA and RNA virus-induced production of type I interferon by recruiting GSK3? to TBK1. Cell Res. 2016;26:613-28 pubmed publisher
Liesche C, Venkatraman L, Aschenbrenner S, Grosse S, Grimm D, Eils R, et al. Death receptor-based enrichment of Cas9-expressing cells. BMC Biotechnol. 2016;16:17 pubmed publisher
Yang Q, Sun G, Cao Z, Yin H, Qi Q, Wang J, et al. The expression of NLRX1 in C57BL/6 mice cochlear hair cells: Possible relation to aging- and neomycin-induced deafness. Neurosci Lett. 2016;616:138-46 pubmed publisher
Xia P, Ye B, Wang S, Zhu X, Du Y, Xiong Z, et al. Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity. Nat Immunol. 2016;17:369-78 pubmed publisher
Zhang G, Chan B, Samarina N, Abere B, Weidner Glunde M, Buch A, et al. Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS. Proc Natl Acad Sci U S A. 2016;113:E1034-43 pubmed publisher
Sali T, Pryke K, Abraham J, Liu A, Archer I, Broeckel R, et al. Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses. PLoS Pathog. 2015;11:e1005324 pubmed publisher
Lin D, Zhang M, Zhang M, Ren Y, Jin J, Zhao Q, et al. Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6. Proc Natl Acad Sci U S A. 2015;112:11324-9 pubmed publisher
Ma Z, Jacobs S, West J, Stopford C, Zhang Z, Davis Z, et al. Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses. Proc Natl Acad Sci U S A. 2015;112:E4306-15 pubmed publisher
Shi Y, Yuan B, Qi N, Zhu W, Su J, Li X, et al. An autoinhibitory mechanism modulates MAVS activity in antiviral innate immune response. Nat Commun. 2015;6:7811 pubmed publisher
He L, Zang A, Du M, Ma D, Yuan C, Zhou C, et al. mTOR regulates TLR-induced c-fos and Th1 responses to HBV and HCV vaccines. Virol Sin. 2015;30:174-89 pubmed publisher
Wang Y, Lian Q, Yang B, Yan S, Zhou H, He L, et al. TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING. PLoS Pathog. 2015;11:e1005012 pubmed publisher
Khan K, DÃ´ F, Marineau A, Doyon P, ClÃ©ment J, Woodgett J, et al. Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/Î²-Catenin Pathway. Mol Cell Biol. 2015;35:3029-43 pubmed publisher
Shoemaker J, Fukuyama S, Eisfeld A, Zhao D, Kawakami E, Sakabe S, et al. An Ultrasensitive Mechanism Regulates Influenza Virus-Induced Inflammation. PLoS Pathog. 2015;11:e1004856 pubmed publisher
Guo X, Liu T, Shi H, Wang J, Ji P, Wang H, et al. Respiratory Syncytial Virus Infection Upregulates NLRC5 and Major Histocompatibility Complex Class I Expression through RIG-I Induction in Airway Epithelial Cells. J Virol. 2015;89:7636-45 pubmed publisher
Malik N, Vollmer S, Nanda S, López Pelaéz M, Prescott A, Gray N, et al. Suppression of interferon Î² gene transcription by inhibitors of bromodomain and extra-terminal (BET) family members. Biochem J. 2015;468:363-72 pubmed publisher
Dong T, Li C, Wang X, Dian L, Zhang X, Li L, et al. Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine. Nat Commun. 2015;6:6522 pubmed publisher
Majumdar T, Chattopadhyay S, Ozhegov E, Dhar J, Goswami R, Sen G, et al. Induction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondii. PLoS Pathog. 2015;11:e1004779 pubmed publisher
Freischmidt A, Wieland T, Richter B, Ruf W, Schaeffer V, MÃ¼ller K, et al. Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nat Neurosci. 2015;18:631-6 pubmed publisher
Kemp M, Lindsey Boltz L, Sancar A. UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1). J Biol Chem. 2015;290:12184-94 pubmed publisher
Liu Y, Zhang Q, Ding Y, Li X, Zhao D, Zhao K, et al. Histone lysine methyltransferase Ezh1 promotes TLR-triggered inflammatory cytokine production by suppressing Tollip. J Immunol. 2015;194:2838-46 pubmed publisher
Kodigepalli K, Nanjundan M. Induction of PLSCR1 in a STING/IRF3-dependent manner upon vector transfection in ovarian epithelial cells. PLoS ONE. 2015;10:e0117464 pubmed publisher
West A, Khoury Hanold W, Staron M, Tal M, Pineda C, Lang S, et al. Mitochondrial DNA stress primes the antiviral innate immune response. Nature. 2015;520:553-7 pubmed publisher
Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, et al. Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B. J Biol Chem. 2015;290:1269-80 pubmed publisher
Banerjee A, Kim Y, Kim T. A novel virus-inducible enhancer of the interferon-Î² gene with tightly linked promoter and enhancer activities. Nucleic Acids Res. 2014;42:12537-54 pubmed publisher
Fork C, Hitzel J, Nichols B, Tikkanen R, Brandes R. Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells. Basic Res Cardiol. 2014;109:439 pubmed publisher
Yang S, Deng P, Zhu Z, Zhu J, Wang G, Zhang L, et al. Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs. J Immunol. 2014;193:3436-45 pubmed publisher
Yen B, Mulder L, Martinez O, Basler C. Molecular basis for ebolavirus VP35 suppression of human dendritic cell maturation. J Virol. 2014;88:12500-10 pubmed publisher
Hayakawa K, Okazaki R, Morioka K, Nakamura K, Tanaka S, Ogata T. Lipopolysaccharide preconditioning facilitates M2 activation of resident microglia after spinal cord injury. J Neurosci Res. 2014;92:1647-58 pubmed publisher
Odendall C, Dixit E, Stavru F, Bierne H, Franz K, Durbin A, et al. Diverse intracellular pathogens activate type III interferon expression from peroxisomes. Nat Immunol. 2014;15:717-26 pubmed publisher
Huang Y, Liu H, Li S, Tang Y, Wei B, Yu H, et al. MAVS-MKK7-JNK2 defines a novel apoptotic signaling pathway during viral infection. PLoS Pathog. 2014;10:e1004020 pubmed publisher
Nandi S, Chanda S, Bagchi P, Nayak M, Bhowmick R, Chawla Sarkar M. MAVS protein is attenuated by rotavirus nonstructural protein 1. PLoS ONE. 2014;9:e92126 pubmed publisher
Xia M, Gonzalez P, Li C, Meng G, Jiang A, Wang H, et al. Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling. J Virol. 2014;88:5152-64 pubmed publisher
Das A, Dinh P, Panda D, Pattnaik A. Interferon-inducible protein IFI35 negatively regulates RIG-I antiviral signaling and supports vesicular stomatitis virus replication. J Virol. 2014;88:3103-13 pubmed publisher
Lam E, Stein S, Falck Pedersen E. Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade. J Virol. 2014;88:974-81 pubmed publisher
Yan K, Zhu W, Yu L, Li N, Zhang X, Liu P, et al. Toll-like receptor 3 and RIG-I-like receptor activation induces innate antiviral responses in mouse ovarian granulosa cells. Mol Cell Endocrinol. 2013;372:73-85 pubmed publisher
Austenaa L, Barozzi I, Chronowska A, Termanini A, Ostuni R, Prosperini E, et al. The histone methyltransferase Wbp7 controls macrophage function through GPI glycolipid anchor synthesis. Immunity. 2012;36:572-85 pubmed publisher

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