This is a Validated Antibody Database (VAD) review about mouse Il2rb, based on 33 published articles (read how Labome selects the articles), using Il2rb antibody in all methods. It is aimed to help Labome visitors find the most suited Il2rb antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Il2rb synonym: CD122; IL-15Rbeta; IL15Rbeta; Il-2/15Rbeta; Il-2Rbeta; p70

Invitrogen
rat monoclonal (TM-b1 (TM-beta1))
  • flow cytometry; mouse; 1:200; loading ...
Invitrogen Il2rb antibody (eBioscience, 12-1222-83) was used in flow cytometry on mouse samples at 1:200. Nat Commun (2021) ncbi
rat monoclonal (TM-b1 (TM-beta1))
  • flow cytometry; mouse; loading ...; fig s2c
Invitrogen Il2rb antibody (eBioscience, 46-1222-82) was used in flow cytometry on mouse samples (fig s2c). Cell (2019) ncbi
rat monoclonal (TM-b1 (TM-beta1))
  • flow cytometry; mouse; loading ...; fig 3a, 3b
Invitrogen Il2rb antibody (eBioscience, TM-beta1) was used in flow cytometry on mouse samples (fig 3a, 3b). Nat Commun (2018) ncbi
rat monoclonal (TM-b1 (TM-beta1))
  • flow cytometry; mouse; fig 1h
Invitrogen Il2rb antibody (eBiosciences, 46-1222-82) was used in flow cytometry on mouse samples (fig 1h). Cell (2018) ncbi
rat monoclonal (TM-b1 (TM-beta1))
  • flow cytometry; mouse; loading ...; fig 5a
Invitrogen Il2rb antibody (eBioscience, TM-beta1) was used in flow cytometry on mouse samples (fig 5a). J Immunol (2017) ncbi
rat monoclonal (TM-b1 (TM-beta1))
  • flow cytometry; mouse; 1:200; loading ...; fig 1a
In order to find genes that alter invariant natural killer T cell development, migration, or function, Invitrogen Il2rb antibody (eBiosciences, TM-b1) was used in flow cytometry on mouse samples at 1:200 (fig 1a). Nat Commun (2016) ncbi
rat monoclonal (TM-b1 (TM-beta1))
  • flow cytometry; mouse; loading ...; fig 2
In order to determine the function of the SLAM family of proteins in natural killer cells, Invitrogen Il2rb antibody (eBioscience, TMb1) was used in flow cytometry on mouse samples (fig 2). J Exp Med (2016) ncbi
rat monoclonal (TM-b1 (TM-beta1))
  • flow cytometry; mouse; loading ...; fig 2e
In order to demonstrate that the negative regulation of T cell receptor signaling during natural killer T cell development regulates NKT1 and NKT2 differentiation and survival, Invitrogen Il2rb antibody (eBioscience, TM-b1) was used in flow cytometry on mouse samples (fig 2e). J Exp Med (2016) ncbi
rat monoclonal (5H4)
  • flow cytometry; mouse; loading ...; fig 3b
In order to investigate the mechanism for adoptively transferred effector T-cell survival and memory formation, Invitrogen Il2rb antibody (eBioscience, 5H4) was used in flow cytometry on mouse samples (fig 3b). Cell Biosci (2016) ncbi
rat monoclonal (TM-b1 (TM-beta1))
  • flow cytometry; mouse; 1:100; fig s2
In order to assess the role of NLRC5 to NK-T-cell crosstalk, Invitrogen Il2rb antibody (eBioscience, TM-b1) was used in flow cytometry on mouse samples at 1:100 (fig s2). Nat Commun (2016) ncbi
rat monoclonal (TM-b1 (TM-beta1))
  • flow cytometry; mouse; 5 ug/ml; fig 3c
Invitrogen Il2rb antibody (eBioscience, Tm-b1) was used in flow cytometry on mouse samples at 5 ug/ml (fig 3c). Nat Commun (2015) ncbi
rat monoclonal (TM-b1 (TM-beta1))
  • flow cytometry; mouse; fig 3
In order to study how DNAM-1 controls NK cell-mediated cytotoxicity and cytokine production, Invitrogen Il2rb antibody (eBioscience, TMb1) was used in flow cytometry on mouse samples (fig 3). J Exp Med (2015) ncbi
rat monoclonal (TM-b1 (TM-beta1))
  • flow cytometry; mouse
In order to investigate the role of thoracic thymus in T cell development and homeostasis, Invitrogen Il2rb antibody (eBioscience, TM-b1) was used in flow cytometry on mouse samples . Eur J Immunol (2014) ncbi
rat monoclonal (5H4)
  • flow cytometry; mouse
In order to study splenic natural killer T cells, Invitrogen Il2rb antibody (eBioscience, 5H4) was used in flow cytometry on mouse samples . EMBO J (2012) ncbi
rat monoclonal (5H4)
  • flow cytometry; mouse; fig 2
In order to examine the role of T-bet in Valpha14i natural killer T cell function, Invitrogen Il2rb antibody (eBioscience, 5H4) was used in flow cytometry on mouse samples (fig 2). Blood (2006) ncbi
BioLegend
rat monoclonal (TM-β1)
  • flow cytometry; mouse; 1:100; loading ...; fig 5s1
BioLegend Il2rb antibody (BioLegend, 123214) was used in flow cytometry on mouse samples at 1:100 (fig 5s1). elife (2021) ncbi
rat monoclonal (5H4)
  • flow cytometry; mouse; loading ...; fig 1c
BioLegend Il2rb antibody (BioLegend, 5H4) was used in flow cytometry on mouse samples (fig 1c). Am J Transplant (2021) ncbi
rat monoclonal (5H4)
  • flow cytometry; mouse; loading ...; fig 5d
BioLegend Il2rb antibody (BioLegend, 5H4) was used in flow cytometry on mouse samples (fig 5d). J Immunol (2019) ncbi
rat monoclonal (5H4)
  • flow cytometry; mouse; loading ...; fig 3c
BioLegend Il2rb antibody (Biolegend, 105905) was used in flow cytometry on mouse samples (fig 3c). Cell Rep (2019) ncbi
rat monoclonal (5H4)
  • flow cytometry; mouse; loading ...; fig s5a
BioLegend Il2rb antibody (Biolegend, 5H4) was used in flow cytometry on mouse samples (fig s5a). Front Immunol (2018) ncbi
rat monoclonal (TM-β1)
  • flow cytometry; mouse; loading ...; fig 3b
In order to study the role of lysine acetyltransferase GCN5 in iNKT cell development and its mechanism, BioLegend Il2rb antibody (BioLegend, 123208) was used in flow cytometry on mouse samples (fig 3b). Cell Rep (2017) ncbi
rat monoclonal (5H4)
  • flow cytometry; mouse; loading ...; fig 3b
In order to study the role of lysine acetyltransferase GCN5 in iNKT cell development and its mechanism, BioLegend Il2rb antibody (BioLegend, 105905) was used in flow cytometry on mouse samples (fig 3b). Cell Rep (2017) ncbi
rat monoclonal (TM-β1)
  • flow cytometry; mouse; fig 1
In order to investigate how organ-specific Btnl genes shape local T cell compartments, BioLegend Il2rb antibody (BioLegend, 123213) was used in flow cytometry on mouse samples (fig 1). Cell (2016) ncbi
rat monoclonal (5H4)
  • flow cytometry; mouse; fig 2
In order to research skin-resident memory T cell homeostasis and lymphoma mediated by hair follicle-derived IL-7 and IL-15, BioLegend Il2rb antibody (BioLegend, 5H4) was used in flow cytometry on mouse samples (fig 2). Nat Med (2015) ncbi
BD Biosciences
rat monoclonal (TM-BETA 1)
  • flow cytometry; mouse; loading ...; fig 2f
BD Biosciences Il2rb antibody (BD Biosciences, 9TM-beta1) was used in flow cytometry on mouse samples (fig 2f). Science (2019) ncbi
rat monoclonal (TM-BETA 1)
  • flow cytometry; mouse; 1:50; loading ...; fig 4d
BD Biosciences Il2rb antibody (BD Biosciences, 562960) was used in flow cytometry on mouse samples at 1:50 (fig 4d). Nat Commun (2018) ncbi
rat monoclonal (TM-BETA 1)
  • flow cytometry; mouse; loading ...; fig 4a
BD Biosciences Il2rb antibody (BD Biosciences, TM-beta1) was used in flow cytometry on mouse samples (fig 4a). J Clin Invest (2018) ncbi
rat monoclonal (5H4)
  • flow cytometry; mouse; loading ...; fig s4
BD Biosciences Il2rb antibody (BD Biosciences, 554452) was used in flow cytometry on mouse samples (fig s4). J Immunol (2018) ncbi
rat monoclonal (TM-BETA 1)
  • flow cytometry; mouse; fig 2d
In order to examine the localization and function of FHL2 in natural killer cells, BD Biosciences Il2rb antibody (BD Biosciences, TM-beta1) was used in flow cytometry on mouse samples (fig 2d). Front Immunol (2017) ncbi
rat monoclonal (TM-BETA 1)
  • flow cytometry; mouse; fig s3b
In order to investigate the mechanisms by which eomesodermin regulates memory fitness in T cells, BD Biosciences Il2rb antibody (BD Pharmingen, TMbeta1) was used in flow cytometry on mouse samples (fig s3b). Proc Natl Acad Sci U S A (2017) ncbi
rat monoclonal (TM-BETA 1)
  • flow cytometry; mouse; fig 1
In order to investigate how organ-specific Btnl genes shape local T cell compartments, BD Biosciences Il2rb antibody (BD, 562960) was used in flow cytometry on mouse samples (fig 1). Cell (2016) ncbi
rat monoclonal (TM-BETA 1)
  • flow cytometry; mouse; loading ...
In order to demonstrate that DNMT3a directs early CD8 positive T-cell effector and memory fate decisions, BD Biosciences Il2rb antibody (BD Biosciences, TM-beta1) was used in flow cytometry on mouse samples . Proc Natl Acad Sci U S A (2016) ncbi
rat monoclonal (5H4)
  • flow cytometry; mouse
BD Biosciences Il2rb antibody (BD Biosciences, 5H4) was used in flow cytometry on mouse samples . J Leukoc Biol (2015) ncbi
rat monoclonal (TM-BETA 1)
  • flow cytometry; mouse
BD Biosciences Il2rb antibody (BD Biosciences, TM-Beta1) was used in flow cytometry on mouse samples . PLoS ONE (2014) ncbi
rat monoclonal (TM-BETA 1)
  • blocking or activating experiments; mouse; fig 2
In order to examine how IL-2-signaling regulates the Bcl-6-Blimp-1 axis in Th1 cells, BD Biosciences Il2rb antibody (BD Biosciences, TM-beta1) was used in blocking or activating experiments on mouse samples (fig 2). Nat Immunol (2012) ncbi
Articles Reviewed
  1. James O, Vandereyken M, Marchingo J, Singh F, Bray S, Wilson J, et al. IL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial lymphocytes. Nat Commun. 2021;12:4290 pubmed publisher
  2. Glassman C, Su L, Majri Morrison S, Winkelmann H, Mo F, Li P, et al. Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist. elife. 2021;10: pubmed publisher
  3. Mahr B, Pilat N, Granofszky N, Muckenhuber M, Unger L, Weijler A, et al. Distinct roles for major and minor antigen barriers in chimerism-based tolerance under irradiation-free conditions. Am J Transplant. 2021;21:968-977 pubmed publisher
  4. Leone R, Zhao L, Englert J, Sun I, Oh M, Sun I, et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 2019;366:1013-1021 pubmed publisher
  5. Collins N, Han S, Enamorado M, Link V, Huang B, Moseman E, et al. The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction. Cell. 2019;178:1088-1101.e15 pubmed publisher
  6. Khanom U, Ohigashi I, Fujimori S, Kondo K, Takada K, Takahama Y. TCR Affinity for In Vivo Peptide-Induced Thymic Positive Selection Fine-Tunes TCR Responsiveness of Peripheral CD8+ T Cells. J Immunol. 2019;: pubmed publisher
  7. Misumi I, Starmer J, Uchimura T, Beck M, Magnuson T, Whitmire J. Obesity Expands a Distinct Population of T Cells in Adipose Tissue and Increases Vulnerability to Infection. Cell Rep. 2019;27:514-524.e5 pubmed publisher
  8. Wang F, Meng M, Mo B, Yang Y, Ji Y, Huang P, et al. Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function. Nat Commun. 2018;9:4874 pubmed publisher
  9. Zhu L, Xie X, Zhang L, Wang H, Jie Z, Zhou X, et al. TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival. Nat Commun. 2018;9:2812 pubmed publisher
  10. Prado C, Gaiazzi M, Gonzalez H, Ugalde V, Figueroa A, Osorio Barrios F, et al. Dopaminergic Stimulation of Myeloid Antigen-Presenting Cells Attenuates Signal Transducer and Activator of Transcription 3-Activation Favouring the Development of Experimental Autoimmune Encephalomyelitis. Front Immunol. 2018;9:571 pubmed publisher
  11. Khan A, Carpenter B, Santos e Sousa P, Pospori C, Khorshed R, Griffin J, et al. Redirection to the bone marrow improves T cell persistence and antitumor functions. J Clin Invest. 2018;128:2010-2024 pubmed publisher
  12. Delong J, Hall A, Konradt C, Coppock G, Park J, Harms Pritchard G, et al. Cytokine- and TCR-Mediated Regulation of T Cell Expression of Ly6C and Sca-1. J Immunol. 2018;200:1761-1770 pubmed publisher
  13. Linehan J, Harrison O, Han S, Byrd A, Vujkovic Cvijin I, Villarino A, et al. Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair. Cell. 2018;172:784-796.e18 pubmed publisher
  14. Muschaweckh A, Petermann F, Korn T. IL-1? and IL-23 Promote Extrathymic Commitment of CD27+CD122- ?? T Cells to ??T17 Cells. J Immunol. 2017;199:2668-2679 pubmed publisher
  15. Wang Y, Yun C, Gao B, Xu Y, Zhang Y, Wang Y, et al. The Lysine Acetyltransferase GCN5 Is Required for iNKT Cell Development through EGR2 Acetylation. Cell Rep. 2017;20:600-612 pubmed publisher
  16. Baranek T, Morello E, Valayer A, Aimar R, Bréa D, Henry C, et al. FHL2 Regulates Natural Killer Cell Development and Activation during Streptococcus pneumoniae Infection. Front Immunol. 2017;8:123 pubmed publisher
  17. Knudson K, Pritzl C, Saxena V, Altman A, Daniels M, Teixeiro E. NFκB-Pim-1-Eomesodermin axis is critical for maintaining CD8 T-cell memory quality. Proc Natl Acad Sci U S A. 2017;114:E1659-E1667 pubmed publisher
  18. Georgiev H, Ravens I, Benarafa C, Forster R, Bernhardt G. Distinct gene expression patterns correlate with developmental and functional traits of iNKT subsets. Nat Commun. 2016;7:13116 pubmed publisher
  19. Di Marco Barros R, Roberts N, Dart R, Vantourout P, Jandke A, Nussbaumer O, et al. Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments. Cell. 2016;167:203-218.e17 pubmed publisher
  20. Ladle B, Li K, Phillips M, Pucsek A, Haile A, Powell J, et al. De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation. Proc Natl Acad Sci U S A. 2016;113:10631-6 pubmed publisher
  21. Guo H, Cranert S, Lu Y, Zhong M, Zhang S, Chen J, et al. Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1. J Exp Med. 2016;213:2187-207 pubmed publisher
  22. Drennan M, Govindarajan S, Verheugen E, Coquet J, Staal J, McGuire C, et al. NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20. J Exp Med. 2016;213:1973-81 pubmed publisher
  23. Xu A, Bhanumathy K, Wu J, Ye Z, Freywald A, Leary S, et al. IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia. Cell Biosci. 2016;6:30 pubmed publisher
  24. Ludigs K, Jandus C, Utzschneider D, Staehli F, Bessoles S, Dang A, et al. NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nat Commun. 2016;7:10554 pubmed publisher
  25. Bothur E, Raifer H, Haftmann C, Stittrich A, Brüstle A, Brenner D, et al. Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1. Nat Commun. 2015;6:8576 pubmed publisher
  26. Zhang Z, Wu N, Lu Y, Davidson D, Colonna M, Veillette A. DNAM-1 controls NK cell activation via an ITT-like motif. J Exp Med. 2015;212:2165-82 pubmed publisher
  27. Adachi T, Kobayashi T, Sugihara E, Yamada T, Ikuta K, Pittaluga S, et al. Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma. Nat Med. 2015;21:1272-9 pubmed publisher
  28. Spada R, Rojas J, Pérez Yagüe S, Mulens V, Cannata Ortiz P, Bragado R, et al. NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery. J Leukoc Biol. 2015;97:583-98 pubmed publisher
  29. Dang V, Tanabe K, Tanaka Y, Tokumoto N, Misumi T, Saeki Y, et al. Fasting enhances TRAIL-mediated liver natural killer cell activity via HSP70 upregulation. PLoS ONE. 2014;9:e110748 pubmed publisher
  30. Smolarchuk C, Zhu L, Chan W, Anderson C. T cells generated in the absence of a thoracic thymus fail to establish homeostasis. Eur J Immunol. 2014;44:2263-73 pubmed publisher
  31. Barral P, Sanchez Nino M, Van Rooijen N, Cerundolo V, Batista F. The location of splenic NKT cells favours their rapid activation by blood-borne antigen. EMBO J. 2012;31:2378-90 pubmed publisher
  32. Oestreich K, Mohn S, Weinmann A. Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile. Nat Immunol. 2012;13:405-11 pubmed publisher
  33. Matsuda J, Zhang Q, Ndonye R, Richardson S, Howell A, Gapin L. T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells. Blood. 2006;107:2797-805 pubmed