This is a Validated Antibody Database (VAD) review about mouse Il22, based on 25 published articles (read how Labome selects the articles), using Il22 antibody in all methods. It is aimed to help Labome visitors find the most suited Il22 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Il22 synonym: IL-22; IL-22a; ILTIFa; Iltif

Invitrogen
rat monoclonal (IL22JOP)
  • flow cytometry; mouse; 1:100; loading ...; fig s9a
Invitrogen Il22 antibody (eBioscience, 17-7222-82) was used in flow cytometry on mouse samples at 1:100 (fig s9a). Nature (2021) ncbi
rat monoclonal (IL22JOP)
  • flow cytometry; mouse; loading ...; fig 1f
Invitrogen Il22 antibody (eBioscience, IL22JOP) was used in flow cytometry on mouse samples (fig 1f). elife (2020) ncbi
rat monoclonal (IL22JOP)
  • flow cytometry; mouse; 1:200; loading ...; fig 8c
Invitrogen Il22 antibody (BioLegend, 17-7222) was used in flow cytometry on mouse samples at 1:200 (fig 8c). Front Immunol (2018) ncbi
rat monoclonal (1H8PWSR)
  • flow cytometry; mouse; fig s2b
In order to study intestinal immune responses during acute graft-versus-host disease, Invitrogen Il22 antibody (eBiosciences, 1H8PWSR) was used in flow cytometry on mouse samples (fig s2b). J Clin Invest (2017) ncbi
rat monoclonal (IL22JOP)
  • flow cytometry; human; loading ...; fig 5a
In order to describe complete autosomal recessive IL-17RA deficiency in patients with chronic mucocutaneous candidiasis, Invitrogen Il22 antibody (Ebiosciences, IL22JOP) was used in flow cytometry on human samples (fig 5a). Proc Natl Acad Sci U S A (2016) ncbi
rat monoclonal (1H8PWSR)
  • flow cytometry; mouse; loading ...; fig 2a
In order to study changes in IL-23 and IL-22 after scratching, Invitrogen Il22 antibody (eBioscience, 1H8PWSR) was used in flow cytometry on mouse samples (fig 2a). J Exp Med (2016) ncbi
rat monoclonal (IL22JOP)
  • flow cytometry; mouse; fig s3g
Invitrogen Il22 antibody (eBioscience, IL22JOP) was used in flow cytometry on mouse samples (fig s3g). Immunity (2016) ncbi
rat monoclonal (1H8PWSR)
  • flow cytometry; mouse; loading ...; fig 1f
In order to explain how glial cells impact ILC3-derived IL-22, Invitrogen Il22 antibody (eBioscience, 1H8PWSR) was used in flow cytometry on mouse samples (fig 1f). Nature (2016) ncbi
rat monoclonal (IL22JOP)
  • flow cytometry; human; fig s12b
In order to find predictive markers for patients that will develop gastrointestinal graft-versus-host-disease, Invitrogen Il22 antibody (eBiosciences, IL22JOP) was used in flow cytometry on human samples (fig s12b). JCI Insight (2016) ncbi
rat monoclonal (IL22JOP)
  • flow cytometry; mouse; fig s4
Invitrogen Il22 antibody (eBioscience, 17-7222-82) was used in flow cytometry on mouse samples (fig s4). Cell (2016) ncbi
rat monoclonal (IL22JOP)
  • flow cytometry; rhesus macaque; fig 1c
Invitrogen Il22 antibody (eBiosciences, IL22JOP) was used in flow cytometry on rhesus macaque samples (fig 1c). J Immunol (2016) ncbi
rat monoclonal (1H8PWSR)
  • flow cytometry; mouse; fig s1d
In order to report that the maternal microbiota shapes the offspring's immune system, Invitrogen Il22 antibody (eBioscinece, 1H8PWSR) was used in flow cytometry on mouse samples (fig s1d). Science (2016) ncbi
rat monoclonal (IL22JOP)
  • flow cytometry; mouse; 1:100; fig s4
Invitrogen Il22 antibody (eBioscience, 17-7222-82) was used in flow cytometry on mouse samples at 1:100 (fig s4). Nat Commun (2015) ncbi
rat monoclonal (1H8PWSR)
  • flow cytometry; mouse; loading ...; fig 3a
Invitrogen Il22 antibody (eBioscience, clone 1H8PWSR) was used in flow cytometry on mouse samples (fig 3a). Cell Host Microbe (2015) ncbi
rat monoclonal (IL22JOP)
  • flow cytometry; human; fig 3
Invitrogen Il22 antibody (eBioscience, 17-7222-82) was used in flow cytometry on human samples (fig 3). Scand J Immunol (2015) ncbi
rat monoclonal (IL22JOP)
  • dot blot; human; tbl s1
In order to use polydimethylsiloxane microchambers to co-detect 42 immune effector proteins secreted from a single LPS-stimulation macrophage, Invitrogen Il22 antibody (Ebioscience, 16- 7222-85) was used in dot blot on human samples (tbl s1). Proc Natl Acad Sci U S A (2015) ncbi
rat monoclonal (IL22JOP)
  • flow cytometry; mouse
Invitrogen Il22 antibody (eBioscience, IL22JOP) was used in flow cytometry on mouse samples . J Exp Med (2014) ncbi
rat monoclonal (1H8PWSR)
  • flow cytometry; mouse; fig 8
In order to identify CD11b(+) classical dendritic cells as the source of IL-23 in C. rodentium infected mice, Invitrogen Il22 antibody (eBioscience, 1H8PWSR) was used in flow cytometry on mouse samples (fig 8). Nat Immunol (2013) ncbi
rat monoclonal (IL22JOP)
  • flow cytometry; African green monkey; loading ...; fig s1b
In order to investigate mucosal dysfunction in relation to HIV/SIV pathogenesis, Invitrogen Il22 antibody (eBioscience, IL22JOP) was used in flow cytometry on African green monkey samples (fig s1b). J Immunol (2013) ncbi
rat monoclonal (1H8PWSR)
  • flow cytometry; mouse
In order to examine IL-7R signaling in Tbx21 and Rag2 knockout mice, Invitrogen Il22 antibody (ebiosciences, IH8PWSR) was used in flow cytometry on mouse samples . Immunity (2012) ncbi
rat monoclonal (IL22JOP)
  • flow cytometry; rhesus macaque
In order to study alterations in mucosal immunity during SIV infection, Invitrogen Il22 antibody (eBioscience, IL22JOP) was used in flow cytometry on rhesus macaque samples . Mucosal Immunol (2012) ncbi
rat monoclonal (1H8PWSR)
  • flow cytometry; mouse; fig s3
Invitrogen Il22 antibody (eBioscience, 1H8PWSR) was used in flow cytometry on mouse samples (fig s3). Nat Immunol (2011) ncbi
BioLegend
domestic goat polyclonal (Poly5164)
  • flow cytometry; mouse; loading ...
BioLegend Il22 antibody (BioLegend, 516411) was used in flow cytometry on mouse samples . Int J Mol Sci (2021) ncbi
domestic goat polyclonal (Poly5164)
  • flow cytometry; mouse; loading ...; fig 3b
BioLegend Il22 antibody (Biolegend, Poly5164) was used in flow cytometry on mouse samples (fig 3b). Sci Rep (2021) ncbi
domestic goat polyclonal (Poly5164)
  • flow cytometry; mouse; loading ...; fig s3a
BioLegend Il22 antibody (BioLegend, Poly5164) was used in flow cytometry on mouse samples (fig s3a). Nat Commun (2016) ncbi
Articles Reviewed
  1. Hering L, Katkeviciute E, Schwarzfischer M, Niechcial A, Riggs J, Wawrzyniak M, et al. Macrophages Compensate for Loss of Protein Tyrosine Phosphatase N2 in Dendritic Cells to Protect from Elevated Colitis. Int J Mol Sci. 2021;22: pubmed publisher
  2. Kong W, Tsuyama N, Inoue H, Guo Y, Mokuda S, Nobukiyo A, et al. Long-chain saturated fatty acids in breast milk are associated with the pathogenesis of atopic dermatitis via induction of inflammatory ILC3s. Sci Rep. 2021;11:13109 pubmed publisher
  3. Bielecki P, Riesenfeld S, Hütter J, Torlai Triglia E, Kowalczyk M, Ricardo Gonzalez R, et al. Skin-resident innate lymphoid cells converge on a pathogenic effector state. Nature. 2021;592:128-132 pubmed publisher
  4. Tizian C, Lahmann A, Hölsken O, Cosovanu C, Kofoed Branzk M, Heinrich F, et al. c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells. elife. 2020;9: pubmed publisher
  5. Glal D, Sudhakar J, Lu H, Liu M, Chiang H, Liu Y, et al. ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases. Front Immunol. 2018;9:2522 pubmed publisher
  6. Bruce D, Stefanski H, Vincent B, Dant T, Reisdorf S, Bommiasamy H, et al. Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease. J Clin Invest. 2017;127:1813-1825 pubmed publisher
  7. Tripathi D, Venkatasubramanian S, Cheekatla S, Paidipally P, Welch E, Tvinnereim A, et al. A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice. Nat Commun. 2016;7:13896 pubmed publisher
  8. Lévy R, Okada S, Béziat V, Moriya K, Liu C, Chai L, et al. Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency. Proc Natl Acad Sci U S A. 2016;113:E8277-E8285 pubmed publisher
  9. Yoon J, Leyva Castillo J, Wang G, Galand C, Oyoshi M, Kumar L, et al. IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. J Exp Med. 2016;213:2147-66 pubmed publisher
  10. Wang S, Xia P, Chen Y, Huang G, Xiong Z, Liu J, et al. Natural Killer-like B Cells Prime Innate Lymphocytes against Microbial Infection. Immunity. 2016;45:131-44 pubmed publisher
  11. Ibiza S, García Cassani B, Ribeiro H, Carvalho T, Almeida L, Marques R, et al. Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence. Nature. 2016;535:440-443 pubmed publisher
  12. Li W, Liu L, Gomez A, Zhang J, Ramadan A, Zhang Q, et al. Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease. JCI Insight. 2016;1: pubmed publisher
  13. Xiong H, Keith J, Samilo D, Carter R, Leiner I, Pamer E. Innate Lymphocyte/Ly6C(hi) Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance. Cell. 2016;165:679-89 pubmed publisher
  14. Rueda C, Presicce P, Jackson C, Miller L, Kallapur S, Jobe A, et al. Lipopolysaccharide-Induced Chorioamnionitis Promotes IL-1-Dependent Inflammatory FOXP3+ CD4+ T Cells in the Fetal Rhesus Macaque. J Immunol. 2016;196:3706-15 pubmed publisher
  15. Gomez de Agüero M, Ganal Vonarburg S, Fuhrer T, Rupp S, Uchimura Y, Li H, et al. The maternal microbiota drives early postnatal innate immune development. Science. 2016;351:1296-302 pubmed publisher
  16. Zanvit P, Konkel J, Jiao X, Kasagi S, Zhang D, Wu R, et al. Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis. Nat Commun. 2015;6:8424 pubmed publisher
  17. Abt M, Lewis B, Caballero S, Xiong H, Carter R, Sušac B, et al. Innate Immune Defenses Mediated by Two ILC Subsets Are Critical for Protection against Acute Clostridium difficile Infection. Cell Host Microbe. 2015;18:27-37 pubmed publisher
  18. Dyring Andersen B, Bonefeld C, Bzorek M, Løvendorf M, Lauritsen J, Skov L, et al. The Vitamin D Analogue Calcipotriol Reduces the Frequency of CD8+ IL-17+ T Cells in Psoriasis Lesions. Scand J Immunol. 2015;82:84-91 pubmed publisher
  19. Lu Y, Xue Q, Eisele M, Sulistijo E, Brower K, Han L, et al. Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands. Proc Natl Acad Sci U S A. 2015;112:E607-15 pubmed publisher
  20. Longman R, Diehl G, Victorio D, Huh J, Galan C, Miraldi E, et al. CX?CR1? mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22. J Exp Med. 2014;211:1571-83 pubmed publisher
  21. Satpathy A, Briseño C, Lee J, Ng D, Manieri N, Kc W, et al. Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol. 2013;14:937-48 pubmed publisher
  22. Canary L, Vinton C, Morcock D, Pierce J, Estes J, Brenchley J, et al. Rate of AIDS progression is associated with gastrointestinal dysfunction in simian immunodeficiency virus-infected pigtail macaques. J Immunol. 2013;190:2959-65 pubmed publisher
  23. Powell N, Walker A, Stolarczyk E, Canavan J, Gökmen M, Marks E, et al. The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells. Immunity. 2012;37:674-84 pubmed publisher
  24. Klatt N, Estes J, Sun X, Ortiz A, Barber J, Harris L, et al. Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection. Mucosal Immunol. 2012;5:646-57 pubmed publisher
  25. Ota N, Wong K, Valdez P, Zheng Y, Crellin N, Diehl L, et al. IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium. Nat Immunol. 2011;12:941-8 pubmed publisher