This is a Validated Antibody Database (VAD) review about mouse IRAK 4, based on 12 published articles (read how Labome selects the articles), using IRAK 4 antibody in all methods. It is aimed to help Labome visitors find the most suited IRAK 4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
IRAK 4 synonym: 8430405M07Rik; 9330209D03Rik; IRAK-4; NY-REN-64

Knockout validation
Invitrogen
mouse monoclonal (2H9)
  • western blot knockout validation; human; fig 5
  • western blot knockout validation; mouse; fig 5
In order to identify species-specific preferences in signaling protein use by comprehensive RNAi-based screening of human and mouse TLR pathways, Invitrogen IRAK 4 antibody (Pierce, MA5-15883) was used in western blot knockout validation on human samples (fig 5) and in western blot knockout validation on mouse samples (fig 5). Sci Signal (2016) ncbi
Abcam
mouse monoclonal (2H9)
  • western blot; mouse; 1:1000; loading ...; fig 6
Abcam IRAK 4 antibody (Abcam, ab119942) was used in western blot on mouse samples at 1:1000 (fig 6). Front Immunol (2021) ncbi
Abnova
mouse monoclonal (2H9)
  • western blot; human; 1:500; loading ...; fig 2g
Abnova IRAK 4 antibody (Abnova, MAB10701) was used in western blot on human samples at 1:500 (fig 2g). Biochem Biophys Res Commun (2018) ncbi
mouse monoclonal (A8A8)
  • western blot; human; 1:500; loading ...; fig 2g
Abnova IRAK 4 antibody (Abnova, MAB2538) was used in western blot on human samples at 1:500 (fig 2g). Biochem Biophys Res Commun (2018) ncbi
Invitrogen
mouse monoclonal (2H9)
  • western blot knockout validation; human; fig 5
  • western blot knockout validation; mouse; fig 5
In order to identify species-specific preferences in signaling protein use by comprehensive RNAi-based screening of human and mouse TLR pathways, Invitrogen IRAK 4 antibody (Pierce, MA5-15883) was used in western blot knockout validation on human samples (fig 5) and in western blot knockout validation on mouse samples (fig 5). Sci Signal (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2d
Cell Signaling Technology IRAK 4 antibody (Cell Signaling, 4363) was used in western blot on mouse samples at 1:1000 (fig 2d). Mol Med (2022) ncbi
domestic rabbit monoclonal (D6D7)
  • western blot; mouse; 1:1000; loading ...; fig 2d
Cell Signaling Technology IRAK 4 antibody (Cell Signaling, 11927) was used in western blot on mouse samples at 1:1000 (fig 2d). Mol Med (2022) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4e
Cell Signaling Technology IRAK 4 antibody (Cell Signaling Technology, 4363) was used in western blot on human samples (fig 4e). Nat Cell Biol (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 6b
Cell Signaling Technology IRAK 4 antibody (Cell Signaling, 4363) was used in western blot on mouse samples (fig 6b). Infect Immun (2017) ncbi
domestic rabbit monoclonal (D6D7)
  • western blot; mouse; fig 6b
Cell Signaling Technology IRAK 4 antibody (Cell Signaling, 11927) was used in western blot on mouse samples (fig 6b). Infect Immun (2017) ncbi
domestic rabbit monoclonal (D6D7)
  • western blot; human; loading ...; fig 4a
In order to study the the activation of T lymphocyte death by Ebola virus glycoprotein, Cell Signaling Technology IRAK 4 antibody (Cell Signaling, 11927S) was used in western blot on human samples (fig 4a). PLoS Pathog (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4a
In order to study the the activation of T lymphocyte death by Ebola virus glycoprotein, Cell Signaling Technology IRAK 4 antibody (Cell Signaling, 4363S) was used in western blot on human samples (fig 4a). PLoS Pathog (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3c
Cell Signaling Technology IRAK 4 antibody (Cell Signaling, 4363) was used in western blot on human samples (fig 3c). Oncotarget (2017) ncbi
domestic rabbit polyclonal
Cell Signaling Technology IRAK 4 antibody (Cell Signaling, 4363) was used . Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:200; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology IRAK 4 antibody (Cell Signaling, 4363P) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D6D7)
  • western blot; human; 1:100; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology IRAK 4 antibody (Cell Signaling, 11927) was used in western blot on human samples at 1:100 (fig st1). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 5d
In order to study the contribution of neutrophil extracellular traps to pulmonary hypertension, Cell Signaling Technology IRAK 4 antibody (Cell Signaling, 4363P) was used in western blot on human samples (fig 5d). Arterioscler Thromb Vasc Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; fig 3
Cell Signaling Technology IRAK 4 antibody (Cell Signaling Tech, 4363) was used in western blot on mouse samples at 1:500 (fig 3). J Am Heart Assoc (2016) ncbi
Articles Reviewed
  1. Zhao L, Li Y, Xu T, Lv Q, Bi X, Liu X, et al. Dendritic cell-mediated chronic low-grade inflammation is regulated by the RAGE-TLR4-PKCβ1 signaling pathway in diabetic atherosclerosis. Mol Med. 2022;28:4 pubmed publisher
  2. Zhang S, Qu J, Wang L, Li M, Xu D, Zhao Y, et al. Activation of Toll-Like Receptor 7 Signaling Pathway in Primary Sjögren's Syndrome-Associated Thrombocytopenia. Front Immunol. 2021;12:637659 pubmed publisher
  3. Liu P, Shah R, Li Y, Arora A, Ung P, Raman R, et al. An IRAK1-PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy. Nat Cell Biol. 2019;21:203-213 pubmed publisher
  4. Hiromura M, Nohtomi K, Mori Y, Kataoka H, Sugano M, Ohnuma K, et al. Caveolin-1, a binding protein of CD26, is essential for the anti-inflammatory effects of dipeptidyl peptidase-4 inhibitors on human and mouse macrophages. Biochem Biophys Res Commun. 2018;495:223-229 pubmed publisher
  5. Naik S, Padhi A, Ganguli G, Sengupta S, Pati S, Das D, et al. Mouse Bone Marrow Sca-1+ CD44+ Mesenchymal Stem Cells Kill Avirulent Mycobacteria but Not Mycobacterium tuberculosis through Modulation of Cathelicidin Expression via the p38 Mitogen-Activated Protein Kinase-Dependent Pathway. Infect Immun. 2017;85: pubmed publisher
  6. Iampietro M, Younan P, Nishida A, Dutta M, Lubaki N, Santos R, et al. Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection. PLoS Pathog. 2017;13:e1006397 pubmed publisher
  7. Mondello P, Derenzini E, Asgari Z, Philip J, Brea E, SESHAN V, et al. Dual inhibition of histone deacetylases and phosphoinositide 3-kinase enhances therapeutic activity against B cell lymphoma. Oncotarget. 2017;8:14017-14028 pubmed publisher
  8. Boro M, Singh V, Balaji K. Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses. Sci Rep. 2016;6:37695 pubmed publisher
  9. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  10. Aldabbous L, Abdul Salam V, McKinnon T, Duluc L, Pepke Zaba J, Southwood M, et al. Neutrophil Extracellular Traps Promote Angiogenesis: Evidence From Vascular Pathology in Pulmonary Hypertension. Arterioscler Thromb Vasc Biol. 2016;36:2078-87 pubmed publisher
  11. Nishikido T, Oyama J, Shiraki A, Komoda H, Node K. Deletion of Apoptosis Inhibitor of Macrophage (AIM)/CD5L Attenuates the Inflammatory Response and Infarct Size in Acute Myocardial Infarction. J Am Heart Assoc. 2016;5:e002863 pubmed publisher
  12. Sun J, Li N, Oh K, Dutta B, Vayttaden S, Lin B, et al. Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use. Sci Signal. 2016;9:ra3 pubmed publisher