This is a Validated Antibody Database (VAD) review about mouse Hspa2, based on 16 published articles (read how Labome selects the articles), using Hspa2 antibody in all methods. It is aimed to help Labome visitors find the most suited Hspa2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Hspa2 synonym: 70kDa; HSP70.2; HSP70A2; Hsp70-2; heat shock-related 70 kDa protein 2; heat shock 70kDa protein 2; heat shock protein 70.2; heat shock protein, 70 kDa 2

Knockout validation
Enzo Life Sciences
mouse monoclonal (N27F3-4)
  • western blot knockout validation; mouse; 1:2000
In order to investigate the impact of autophagy on photoreceptors, Enzo Life Sciences Hspa2 antibody (Enzo, ADI-SPA-820) was used in western blot knockout validation on mouse samples at 1:2000. Cell Death Differ (2015) ncbi
Enzo Life Sciences
mouse monoclonal (N27F3-4)
  • western blot; human; 1:1000; loading ...; fig 6a
Enzo Life Sciences Hspa2 antibody (Enzo, N27F3-4) was used in western blot on human samples at 1:1000 (fig 6a). Sci Rep (2018) ncbi
mouse monoclonal (N27F3-4)
  • western blot; human; 1:2000; loading ...; fig sf10a
In order to describe a function for NQO1 in stabilizing HIF-1alpha, Enzo Life Sciences Hspa2 antibody (Stratagene, ADI-SPA-820D) was used in western blot on human samples at 1:2000 (fig sf10a). Nat Commun (2016) ncbi
mouse monoclonal (N27F3-4)
  • western blot; Nicotiana benthamiana; fig 1b
Enzo Life Sciences Hspa2 antibody (Enzo Life Sciences, ADI-SPA-820-F) was used in western blot on Nicotiana benthamiana samples (fig 1b). J Virol (2017) ncbi
mouse monoclonal (N27F3-4)
  • western blot; mouse; 1:1000; fig 4
Enzo Life Sciences Hspa2 antibody (ENZO, N27F3-4) was used in western blot on mouse samples at 1:1000 (fig 4). MBio (2016) ncbi
mouse monoclonal (BB70)
  • immunoprecipitation; human; fig 3
In order to characterize novel pancreas-targeting activity through the binding of Sec 61 by Apratoxin A, Enzo Life Sciences Hspa2 antibody (Enzo, BB70) was used in immunoprecipitation on human samples (fig 3). Mol Cancer Ther (2016) ncbi
mouse monoclonal (BB70)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Enzo Life Sciences Hspa2 antibody (ENZO, BB70) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (N27F3-4)
  • western blot; mouse; fig 4b
In order to use gene therapy to generate a receptor fusion protein that targets IL-6, Enzo Life Sciences Hspa2 antibody (Enzo Life Sciences, ADI-SPA-820) was used in western blot on mouse samples (fig 4b). Sci Rep (2015) ncbi
mouse monoclonal (N27F3-4)
  • western blot; mouse; 1:1000; fig 5
Enzo Life Sciences Hspa2 antibody (Enzo Life Sciences, ADI-SPA-820) was used in western blot on mouse samples at 1:1000 (fig 5). Mol Med Rep (2015) ncbi
mouse monoclonal (N27F3-4)
  • western blot knockout validation; mouse; 1:2000
In order to investigate the impact of autophagy on photoreceptors, Enzo Life Sciences Hspa2 antibody (Enzo, ADI-SPA-820) was used in western blot knockout validation on mouse samples at 1:2000. Cell Death Differ (2015) ncbi
mouse monoclonal (N27F3-4)
  • western blot; mouse; 1:1000
In order to determine the effect of STA-2842 on liver size and cystic burden in Pkd-/- mice with established polycystic liver disease, Enzo Life Sciences Hspa2 antibody (Enzo, ADI-SPA-820) was used in western blot on mouse samples at 1:1000. PLoS ONE (2014) ncbi
mouse monoclonal (N27F3-4)
  • flow cytometry; human
Enzo Life Sciences Hspa2 antibody (Alexis Biochemicals, ADI-SPA-820PE-D) was used in flow cytometry on human samples . Cytometry A (2014) ncbi
mouse monoclonal (N27F3-4)
  • western blot; human; 1:1000
Enzo Life Sciences Hspa2 antibody (Enzo Life Sciences, ADI-SPA-820-D) was used in western blot on human samples at 1:1000. Oncogene (2013) ncbi
mouse monoclonal (N27F3-4)
  • western blot; rat
In order to investigate the mechanism for neuronal nitric-oxide synthase activity and degradation, Enzo Life Sciences Hspa2 antibody (Enzo Life Sciences, N27F3-4) was used in western blot on rat samples . J Biol Chem (2012) ncbi
Abcam
rabbit monoclonal (EPR4596)
  • western blot; human; fig s2f
Abcam Hspa2 antibody (Abcam, ab108416) was used in western blot on human samples (fig s2f). Am J Respir Crit Care Med (2018) ncbi
rabbit monoclonal (EPR4596)
  • immunocytochemistry; mouse; loading ...; fig 6a2
Abcam Hspa2 antibody (Abcam, EPR4596) was used in immunocytochemistry on mouse samples (fig 6a2). Stem Cell Res (2016) ncbi
Proteintech Group
rabbit polyclonal
  • immunocytochemistry; mouse; 1:500; loading ...; fig 5a
Proteintech Group Hspa2 antibody (ProteinTech, 12797-1-AP) was used in immunocytochemistry on mouse samples at 1:500 (fig 5a). Biol Reprod (2018) ncbi
Articles Reviewed
  1. Tamaki Y, Shodai A, Morimura T, Hikiami R, Minamiyama S, Ayaki T, et al. Elimination of TDP-43 inclusions linked to amyotrophic lateral sclerosis by a misfolding-specific intrabody with dual proteolytic signals. Sci Rep. 2018;8:6030 pubmed publisher
  2. Ghosh A, Coakley R, Mascenik T, Rowell T, Davis E, Rogers K, et al. Chronic E-Cigarette Exposure Alters the Human Bronchial Epithelial Proteome. Am J Respir Crit Care Med. 2018;198:67-76 pubmed publisher
  3. Hu J, Sun F, Handel M. Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice. Biol Reprod. 2018;98:102-114 pubmed publisher
  4. Oh E, Kim J, Kim J, Kim S, Lee J, Hong S, et al. NQO1 inhibits proteasome-mediated degradation of HIF-1α. Nat Commun. 2016;7:13593 pubmed publisher
  5. Alam S, Rochon D. Evidence that Hsc70 Is Associated with Cucumber Necrosis Virus Particles and Plays a Role in Particle Disassembly. J Virol. 2017;91: pubmed publisher
  6. Gunnarsson A, Christensen R, Li J, Jensen U. Global gene expression and comparison between multiple populations in the mouse epidermis. Stem Cell Res. 2016;17:191-202 pubmed publisher
  7. Liu S, Hossinger A, Hofmann J, Denner P, Vorberg I. Horizontal Transmission of Cytosolic Sup35 Prions by Extracellular Vesicles. MBio. 2016;7: pubmed publisher
  8. Huang K, Chen Z, Jiang Y, Akare S, Kolber Simonds D, Condon K, et al. Apratoxin A Shows Novel Pancreas-Targeting Activity through the Binding of Sec 61. Mol Cancer Ther. 2016;15:1208-16 pubmed publisher
  9. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  10. Görtz D, Braun G, Maruta Y, Djudjaj S, van Roeyen C, Martin I, et al. Anti-interleukin-6 therapy through application of a monogenic protein inhibitor via gene delivery. Sci Rep. 2015;5:14685 pubmed publisher
  11. Jiang Q, Zhang Z, Li S, Wang Z, Ma Y, Hu Y. Defective heat shock factor 1 inhibits the growth of fibrosarcoma derived from simian virus 40/T antigen‑transformed MEF cells. Mol Med Rep. 2015;12:6517-26 pubmed publisher
  12. Zhou Z, Doggett T, Sene A, Apte R, Ferguson T. Autophagy supports survival and phototransduction protein levels in rod photoreceptors. Cell Death Differ. 2015;22:488-98 pubmed publisher
  13. Smithline Z, Nikonova A, Hensley H, Cai K, Egleston B, Proia D, et al. Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice. PLoS ONE. 2014;9:e114403 pubmed publisher
  14. Cao F, Xu L, Zhang X, Wang Y, Li M, Uzan G, et al. IP-FCM platform detects the existence and regulator-caused dissociation of components in naturally assembled HSP90 complex. Cytometry A. 2014;85:359-67 pubmed publisher
  15. Chatain N, Ziegler P, Fahrenkamp D, Jost E, Moriggl R, Schmitz Van de Leur H, et al. Src family kinases mediate cytoplasmic retention of activated STAT5 in BCR-ABL-positive cells. Oncogene. 2013;32:3587-97 pubmed publisher
  16. Peng H, Morishima Y, Pratt W, Osawa Y. Modulation of heme/substrate binding cleft of neuronal nitric-oxide synthase (nNOS) regulates binding of Hsp90 and Hsp70 proteins and nNOS ubiquitination. J Biol Chem. 2012;287:1556-65 pubmed publisher