This is a Validated Antibody Database (VAD) review about mouse Hnrnpl, based on 19 published articles (read how Labome selects the articles), using Hnrnpl antibody in all methods. It is aimed to help Labome visitors find the most suited Hnrnpl antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Hnrnpl synonym: C79783; D830027H13Rik; Hnrpl; heterogeneous nuclear ribonucleoprotein L; hnRNP L

Abcam
mouse monoclonal (4D11)
  • proximity ligation assay; human; 1:200; fig 3c
  • western blot; human; 1:2000; fig 2c
  • immunohistochemistry - paraffin section; mouse; 1:100
Abcam Hnrnpl antibody (Abcam, ab6106) was used in proximity ligation assay on human samples at 1:200 (fig 3c), in western blot on human samples at 1:2000 (fig 2c) and in immunohistochemistry - paraffin section on mouse samples at 1:100. Sci Rep (2017) ncbi
mouse monoclonal (4D11)
  • western blot; mouse; fig 7
In order to characterize the involvement of concerted non-productive splicing of post-transcriptional regulators that involves the alternative splicing program of differentiatied smooth muscle cells, Abcam Hnrnpl antibody (Abcam, ab6106) was used in western blot on mouse samples (fig 7). Nucleic Acids Res (2016) ncbi
mouse monoclonal (4D11)
  • RNA immunoprecipitation; human
In order to develop reagents to study RNA binding proteins, Abcam Hnrnpl antibody (Abcam, ab6106) was used in RNA immunoprecipitation on human samples . Mol Cell (2016) ncbi
mouse monoclonal (4D11)
  • immunocytochemistry; human; fig 2
In order to analyze flat-mounted human corneas by optimizing immunostaining, Abcam Hnrnpl antibody (Abcam, 4D11) was used in immunocytochemistry on human samples (fig 2). Mol Vis (2015) ncbi
mouse monoclonal (4D11)
In order to characterize human osteosarcoma U2OS cells for genome landscape of SRSF3-regulated splicing events and gene expression, Abcam Hnrnpl antibody (Abcam, 4D11) was used . Nucleic Acids Res (2016) ncbi
mouse monoclonal (4D11)
  • western blot; mouse; fig 5
Abcam Hnrnpl antibody (Abcam, ab6106) was used in western blot on mouse samples (fig 5). PLoS ONE (2015) ncbi
mouse monoclonal (4D11)
  • western blot; human; fig 3
In order to assess JNK-dependent alternative splicing in T-cell activation through CELF2-mediated regulation of MKK7, Abcam Hnrnpl antibody (Abcam, ab6106) was used in western blot on human samples (fig 3). Genes Dev (2015) ncbi
mouse monoclonal (4D11)
  • western blot; human
In order to investigate the interaction between TRAP150 and PSF and its effect in T cells, Abcam Hnrnpl antibody (Abcam, 4D11) was used in western blot on human samples . Nucleic Acids Res (2015) ncbi
mouse monoclonal (4D11)
  • immunoprecipitation; human; fig 6
  • western blot; human; fig 4
Abcam Hnrnpl antibody (Abcam, ab6106) was used in immunoprecipitation on human samples (fig 6) and in western blot on human samples (fig 4). PLoS ONE (2015) ncbi
mouse monoclonal (4D11)
  • western blot; mouse; fig 5
Abcam Hnrnpl antibody (Abcam, ab6106) was used in western blot on mouse samples (fig 5). Methods (2014) ncbi
mouse monoclonal (4D11)
  • western blot; human
Abcam Hnrnpl antibody (Abcam, ab6106) was used in western blot on human samples . Genome Res (2014) ncbi
mouse monoclonal (4D11)
  • western blot; human
Abcam Hnrnpl antibody (Abcam, ab6106) was used in western blot on human samples . Nucleic Acids Res (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (4D11)
  • RNA immunoprecipitation; human; loading ...; fig s4b
  • immunohistochemistry - paraffin section; human; loading ...; fig 6b
Santa Cruz Biotechnology Hnrnpl antibody (SantaCruz, 4D11) was used in RNA immunoprecipitation on human samples (fig s4b) and in immunohistochemistry - paraffin section on human samples (fig 6b). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal
  • RNA immunoprecipitation; human; loading ...; fig s4b
Santa Cruz Biotechnology Hnrnpl antibody (SantaCruz, 4D11) was used in RNA immunoprecipitation on human samples (fig s4b). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (D-5)
  • RNA immunoprecipitation; human; loading ...; fig s4b
Santa Cruz Biotechnology Hnrnpl antibody (SantaCruz, sc-48391) was used in RNA immunoprecipitation on human samples (fig s4b). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (4D11)
  • immunohistochemistry; human; loading ...; fig 6a
  • western blot; human; loading ...; fig 2b
In order to explore the function of heterogeneous nuclear ribonucleoprotein L in oral squamous cell carcinoma, Santa Cruz Biotechnology Hnrnpl antibody (Santa Cruz, 4D11) was used in immunohistochemistry on human samples (fig 6a) and in western blot on human samples (fig 2b). Sci Rep (2016) ncbi
mouse monoclonal (4D11)
  • western blot; human; 1:5000; fig 1
Santa Cruz Biotechnology Hnrnpl antibody (Santa Cruz, sc32317) was used in western blot on human samples at 1:5000 (fig 1). Nat Commun (2016) ncbi
mouse monoclonal (4D11)
  • western blot; human
Santa Cruz Biotechnology Hnrnpl antibody (Santa Cruz Biotech, 4D11) was used in western blot on human samples . Biochim Biophys Acta (2015) ncbi
mouse monoclonal (4D11)
  • western blot; human; fig 3f
Santa Cruz Biotechnology Hnrnpl antibody (Santa, sc-32317) was used in western blot on human samples (fig 3f). Sci Rep (2014) ncbi
mouse monoclonal (4D11)
  • RNA immunoprecipitation; human; loading ...; fig 6a
Santa Cruz Biotechnology Hnrnpl antibody (Santa Cruz, sc-32317) was used in RNA immunoprecipitation on human samples (fig 6a). Mol Cancer (2014) ncbi
MilliporeSigma
mouse monoclonal (4D11)
  • western blot; human; fig ev2b
MilliporeSigma Hnrnpl antibody (Sigma-Aldrich, R4903) was used in western blot on human samples (fig ev2b). EMBO J (2015) ncbi
Articles Reviewed
  1. Fei T, Chen Y, Xiao T, Li W, Cato L, Zhang P, et al. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc Natl Acad Sci U S A. 2017;114:E5207-E5215 pubmed publisher
  2. Coppin L, Vincent A, Frénois F, Duchene B, Lahdaoui F, Stechly L, et al. Galectin-3 is a non-classic RNA binding protein that stabilizes the mucin MUC4 mRNA in the cytoplasm of cancer cells. Sci Rep. 2017;7:43927 pubmed publisher
  3. Jia R, Zhang S, Liu M, Zhang Y, Liu Y, Fan M, et al. HnRNP L is important for the expression of oncogene SRSF3 and oncogenic potential of oral squamous cell carcinoma cells. Sci Rep. 2016;6:35976 pubmed publisher
  4. Wilhelmi I, Kanski R, Neumann A, Herdt O, Hoff F, Jacob R, et al. Sec16 alternative splicing dynamically controls COPII transport efficiency. Nat Commun. 2016;7:12347 pubmed publisher
  5. Llorian M, Gooding C, Bellora N, Hallegger M, Buckroyd A, Wang X, et al. The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators. Nucleic Acids Res. 2016;44:8933-8950 pubmed
  6. Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016;61:903-13 pubmed publisher
  7. Forest F, Thuret G, Gain P, Dumollard J, Peoc h M, Perrache C, et al. Optimization of immunostaining on flat-mounted human corneas. Mol Vis. 2015;21:1345-56 pubmed
  8. Ajiro M, Jia R, Yang Y, Zhu J, Zheng Z. A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells. Nucleic Acids Res. 2016;44:1854-70 pubmed publisher
  9. Kim S, Sim C, Tang H, Han W, Zhang K, Xu F. Acetylome Analysis Identifies SIRT1 Targets in mRNA-Processing and Chromatin-Remodeling in Mouse Liver. PLoS ONE. 2015;10:e0140619 pubmed publisher
  10. Martinez N, Agosto L, Qiu J, Mallory M, Gazzara M, Barash Y, et al. Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation. Genes Dev. 2015;29:2054-66 pubmed publisher
  11. Yao X, Tang Z, Fu X, Yin J, Liang Y, Li C, et al. The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination. EMBO J. 2015;34:2885-902 pubmed publisher
  12. Yarosh C, Tapescu I, Thompson M, Qiu J, Mallory M, Fu X, et al. TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells. Nucleic Acids Res. 2015;43:9006-16 pubmed publisher
  13. Roda D, Castillo J, Telechea Fernández M, Gil A, López Rodas G, Franco L, et al. EGF-Induced Acetylation of Heterogeneous Nuclear Ribonucleoproteins Is Dependent on KRAS Mutational Status in Colorectal Cancer Cells. PLoS ONE. 2015;10:e0130543 pubmed publisher
  14. Koumbadinga G, Mahmood N, Lei L, Kan Y, Cao W, Lobo V, et al. Increased stability of heterogeneous ribonucleoproteins by a deacetylase inhibitor. Biochim Biophys Acta. 2015;1849:1095-103 pubmed publisher
  15. Nasrin F, Rahman M, Masuda A, Ohe K, Takeda J, Ohno K. HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform. Sci Rep. 2014;4:6841 pubmed publisher
  16. DERY K, Kujawski M, Grunert D, Wu X, Ngyuen T, Cheung C, et al. IRF-1 regulates alternative mRNA splicing of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in breast epithelial cells generating an immunoreceptor tyrosine-based inhibition motif (ITIM) containing isoform. Mol Cancer. 2014;13:64 pubmed publisher
  17. Gazzara M, Vaquero Garcia J, Lynch K, Barash Y. In silico to in vivo splicing analysis using splicing code models. Methods. 2014;67:3-12 pubmed publisher
  18. Gregory B, Cheung V. Natural variation in the histone demethylase, KDM4C, influences expression levels of specific genes including those that affect cell growth. Genome Res. 2014;24:52-63 pubmed publisher
  19. Peddigari S, Li P, Rabe J, Martin S. hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition. Nucleic Acids Res. 2013;41:575-85 pubmed publisher