This is a Validated Antibody Database (VAD) review about mouse Hnf4a, based on 18 published articles (read how Labome selects the articles), using Hnf4a antibody in all methods. It is aimed to help Labome visitors find the most suited Hnf4a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Hnf4a synonym: HNF-4; Hnf4; Hnf4alpha; MODY1; Nr2a1; TCF-14; Tcf14

Abcam
mouse monoclonal (K9218)
  • immunohistochemistry; mouse; 1:200; loading ...; fig 1c
Abcam Hnf4a antibody (abcam, ab41898) was used in immunohistochemistry on mouse samples at 1:200 (fig 1c). Nat Commun (2022) ncbi
mouse monoclonal (K9218)
  • immunohistochemistry; human; 1:1000; loading ...; fig 3
Abcam Hnf4a antibody (Abcam, ab41898) was used in immunohistochemistry on human samples at 1:1000 (fig 3). Front Med (Lausanne) (2021) ncbi
domestic rabbit monoclonal (EPR16885)
  • immunohistochemistry; mouse; 1:50; loading ...; fig 3e
Abcam Hnf4a antibody (Abcam, ab181604) was used in immunohistochemistry on mouse samples at 1:50 (fig 3e). Dis Model Mech (2021) ncbi
domestic rabbit monoclonal (EPR16885-99)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1b
Abcam Hnf4a antibody (Abcam, ab201460) was used in immunohistochemistry - paraffin section on human samples (fig 1b). EBioMedicine (2021) ncbi
mouse monoclonal (K9218)
  • immunocytochemistry; rat; loading ...; fig 2a
Abcam Hnf4a antibody (Abcam, 41898) was used in immunocytochemistry on rat samples (fig 2a). PLoS ONE (2019) ncbi
mouse monoclonal (K9218)
  • western blot; mouse; loading ...; fig 8b
Abcam Hnf4a antibody (Abcam, ab41898) was used in western blot on mouse samples (fig 8b). J Cell Biol (2017) ncbi
mouse monoclonal (K9218)
  • flow cytometry; human; loading ...; fig 6
  • immunocytochemistry; human; fig 4a
In order to characterize the effect of the growth factor Activin A during early human embryonic stem cell fate determination in cardiac differentiation, Abcam Hnf4a antibody (Abcam, K9218) was used in flow cytometry on human samples (fig 6) and in immunocytochemistry on human samples (fig 4a). Stem Cells Int (2017) ncbi
mouse monoclonal (K9218)
  • immunocytochemistry; rat; loading ...; fig 5a
  • immunocytochemistry; human; loading ...; fig 5b
Abcam Hnf4a antibody (Abcam, ab41898) was used in immunocytochemistry on rat samples (fig 5a) and in immunocytochemistry on human samples (fig 5b). Toxicol In Vitro (2017) ncbi
mouse monoclonal (K9218)
  • immunocytochemistry; mouse; 1:1000; fig 7
Abcam Hnf4a antibody (Abcam, ab41898) was used in immunocytochemistry on mouse samples at 1:1000 (fig 7). Sci Rep (2016) ncbi
mouse monoclonal (K9218)
  • chromatin immunoprecipitation; human; fig s9
Abcam Hnf4a antibody (Abcam, ab41898) was used in chromatin immunoprecipitation on human samples (fig s9). Nucleic Acids Res (2016) ncbi
mouse monoclonal (K9218)
  • immunohistochemistry; mouse; fig 1
Abcam Hnf4a antibody (Abcam, ab41898) was used in immunohistochemistry on mouse samples (fig 1). Nat Commun (2016) ncbi
mouse monoclonal (K9218)
  • immunocytochemistry; human; fig 1
Abcam Hnf4a antibody (Abcam, ab41898) was used in immunocytochemistry on human samples (fig 1). Mol Cancer (2015) ncbi
mouse monoclonal (K9218)
  • immunohistochemistry - paraffin section; mouse; fig 5
  • immunohistochemistry - paraffin section; human; fig 5
Abcam Hnf4a antibody (Abcam, ab41898) was used in immunohistochemistry - paraffin section on mouse samples (fig 5) and in immunohistochemistry - paraffin section on human samples (fig 5). Nat Genet (2015) ncbi
mouse monoclonal (K9218)
  • immunohistochemistry - paraffin section; human; 1:70
Abcam Hnf4a antibody (Abcam, ab41898) was used in immunohistochemistry - paraffin section on human samples at 1:70. PLoS ONE (2014) ncbi
mouse monoclonal (K9218)
  • western blot; human; fig 2
Abcam Hnf4a antibody (Abcam, ab41898) was used in western blot on human samples (fig 2). Nature (2014) ncbi
mouse monoclonal (K9218)
  • chromatin immunoprecipitation; mouse
Abcam Hnf4a antibody (Abcam, ab41898) was used in chromatin immunoprecipitation on mouse samples . J Biol Chem (2013) ncbi
mouse monoclonal (K9218)
  • chromatin immunoprecipitation; mouse
  • chromatin immunoprecipitation; human
Abcam Hnf4a antibody (Abcam, ab41898) was used in chromatin immunoprecipitation on mouse samples and in chromatin immunoprecipitation on human samples . PLoS ONE (2013) ncbi
Invitrogen
mouse monoclonal (K9218)
  • immunoprecipitation; mouse; loading ...; fig 3c
  • immunocytochemistry; mouse; loading ...; fig 6a
  • western blot; mouse; loading ...; fig 1b
Invitrogen Hnf4a antibody (Thermo Fisher, MA1-199) was used in immunoprecipitation on mouse samples (fig 3c), in immunocytochemistry on mouse samples (fig 6a) and in western blot on mouse samples (fig 1b). Mol Cell Biol (2018) ncbi
Articles Reviewed
  1. Bahn M, Yu D, Lee M, Jo S, Lee J, Kim H, et al. Central role of Prominin-1 in lipid rafts during liver regeneration. Nat Commun. 2022;13:6219 pubmed publisher
  2. Wu C, Cheng D, Peng Y, Li Y, Fu C, Wang Y, et al. Hepatic BRD4 Is Upregulated in Liver Fibrosis of Various Etiologies and Positively Correlated to Fibrotic Severity. Front Med (Lausanne). 2021;8:683506 pubmed publisher
  3. Niborski L, Paces Fessy M, Ricci P, Bourgeois A, Magalh xe3 es P, Kuzma Kuzniarska M, et al. Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. Dis Model Mech. 2021;14: pubmed publisher
  4. Wang H, Huang J, Sue M, Ho W, Hsu Y, Chang K, et al. Interleukin-24 protects against liver injury in mouse models. EBioMedicine. 2021;64:103213 pubmed publisher
  5. Alsaeedi F, Wilson R, Candlish C, Ibrahim I, Leitch A, Abdelghany T, et al. Expression of serine/threonine protein kinase SGK1F promotes an hepatoblast state in stem cells directed to differentiate into hepatocytes. PLoS ONE. 2019;14:e0218135 pubmed publisher
  6. Bi Y, Shi X, Zhu J, Guan X, Garbacz W, Huang Y, et al. Regulation of Cholesterol Sulfotransferase SULT2B1b by Hepatocyte Nuclear Factor 4α Constitutes a Negative Feedback Control of Hepatic Gluconeogenesis. Mol Cell Biol. 2018;38: pubmed publisher
  7. Yao J, Guihard P, Wu X, Blázquez Medela A, Spencer M, Jumabay M, et al. Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. J Cell Biol. 2017;216:3369-3385 pubmed publisher
  8. Duelen R, Gilbert G, Patel A, de Schaetzen N, de Waele L, Roderick L, et al. Activin A Modulates CRIPTO-1/HNF4?+ Cells to Guide Cardiac Differentiation from Human Embryonic Stem Cells. Stem Cells Int. 2017;2017:4651238 pubmed publisher
  9. Chang S, Voellinger J, Van Ness K, Chapron B, Shaffer R, Neumann T, et al. Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity. Toxicol In Vitro. 2017;40:170-183 pubmed publisher
  10. Moshfegh C, Aires L, Kisielow M, Vogel V. A gonogenic stimulated transition of mouse embryonic stem cells with enhanced control of diverse differentiation pathways. Sci Rep. 2016;6:25104 pubmed publisher
  11. Chang H, Liu Y, Xue M, Liu H, Du S, Zhang L, et al. Synergistic action of master transcription factors controls epithelial-to-mesenchymal transition. Nucleic Acids Res. 2016;44:2514-27 pubmed publisher
  12. Wang P, Zhang X, Luo P, Jiang X, Zhang P, Guo J, et al. Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling. Nat Commun. 2016;7:10592 pubmed publisher
  13. Conigliaro A, Costa V, Lo Dico A, Saieva L, Buccheri S, Dieli F, et al. CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA. Mol Cancer. 2015;14:155 pubmed publisher
  14. Liao J, Karnik R, Gu H, Ziller M, Clement K, Tsankov A, et al. Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells. Nat Genet. 2015;47:469-78 pubmed publisher
  15. Simeone P, Trerotola M, Urbanella A, Lattanzio R, Ciavardelli D, Di Giuseppe F, et al. A unique four-hub protein cluster associates to glioblastoma progression. PLoS ONE. 2014;9:e103030 pubmed publisher
  16. Saha S, Parachoniak C, Ghanta K, Fitamant J, Ross K, Najem M, et al. Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer. Nature. 2014;513:110-4 pubmed publisher
  17. Tümer E, Bröer A, Balkrishna S, Jülich T, Broer S. Enterocyte-specific regulation of the apical nutrient transporter SLC6A19 (B(0)AT1) by transcriptional and epigenetic networks. J Biol Chem. 2013;288:33813-23 pubmed publisher
  18. Ouyang H, Qin Y, Liu Y, Xie Y, Liu J. Prox1 directly interacts with LSD1 and recruits the LSD1/NuRD complex to epigenetically co-repress CYP7A1 transcription. PLoS ONE. 2013;8:e62192 pubmed publisher