This is a Validated Antibody Database (VAD) review about mouse Hmga2, based on 11 published articles (read how Labome selects the articles), using Hmga2 antibody in all methods. It is aimed to help Labome visitors find the most suited Hmga2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Hmga2 synonym: 9430083A20Rik; HMGI-C; Hmgic; pygmy; high mobility group protein HMGI-C; high mobility group AT-hook protein 2; high mobility group protein I

Abcam
rabbit polyclonal
  • western blot; mouse; fig 5b
Abcam Hmga2 antibody (Abcam, ab97276) was used in western blot on mouse samples (fig 5b). RNA (2015) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; loading ...; fig 3c
Cell Signaling Technology Hmga2 antibody (Cell Signaling, 5269S) was used in western blot on human samples (fig 3c). Cancer Cell (2018) ncbi
rabbit monoclonal (D1A7)
  • western blot; human; loading ...; fig 4a
In order to investigate the effect off miR-509-5p and miR-1243 on gemcitabine efficacy in pancreatic cancer and its mechanism, Cell Signaling Technology Hmga2 antibody (Cell Signaling, 8179) was used in western blot on human samples (fig 4a). Sci Rep (2017) ncbi
rabbit monoclonal (D1A7)
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 3
  • immunohistochemistry - paraffin section; human; 1:400; loading ...; fig 1
Cell Signaling Technology Hmga2 antibody (Cell Signaling, 8179) was used in immunohistochemistry - paraffin section on mouse samples at 1:400 (fig 3) and in immunohistochemistry - paraffin section on human samples at 1:400 (fig 1). Br J Cancer (2017) ncbi
rabbit monoclonal (D1A7)
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology Hmga2 antibody (Cell Signaling, 8179) was used in western blot on human samples at 1:1000 (fig 3b). J Drug Target (2017) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; mouse; 1:100; fig 6a
  • western blot; mouse; 1:500; fig 1d
Cell Signaling Technology Hmga2 antibody (Cell Signaling, 5269) was used in chromatin immunoprecipitation on mouse samples at 1:100 (fig 6a) and in western blot on mouse samples at 1:500 (fig 1d). BMC Biol (2016) ncbi
rabbit monoclonal (D1A7)
  • western blot; human; loading ...; fig 4c
In order to present the role of nuclear Src and p300 signaling axis in pancreatic cancer, Cell Signaling Technology Hmga2 antibody (Cell Signaling, D1A7) was used in western blot on human samples (fig 4c). Oncotarget (2016) ncbi
rabbit monoclonal (D1A7)
  • western blot; mouse; 1:1000; fig s1
Cell Signaling Technology Hmga2 antibody (Cell Signalling, 8179) was used in western blot on mouse samples at 1:1000 (fig s1). Nat Commun (2015) ncbi
rabbit monoclonal (D1A7)
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 3d
Cell Signaling Technology Hmga2 antibody (Cell Signaling, 8179) was used in immunohistochemistry - paraffin section on mouse samples at 1:400 (fig 3d). PLoS Genet (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology Hmga2 antibody (Cell Signaling, 5269) was used in western blot on human samples . PLoS Genet (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100
  • immunocytochemistry; human
Cell Signaling Technology Hmga2 antibody (Cell Signaling, 5269) was used in immunohistochemistry - paraffin section on human samples at 1:100 and in immunocytochemistry on human samples . Cancer Res (2013) ncbi
Articles Reviewed
  1. Stewart E, McEvoy J, Wang H, Chen X, Honnell V, Ocarz M, et al. Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses. Cancer Cell. 2018;34:411-426.e19 pubmed publisher
  2. Hiramoto H, Muramatsu T, Ichikawa D, Tanimoto K, Yasukawa S, Otsuji E, et al. miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer. Sci Rep. 2017;7:4002 pubmed publisher
  3. Strell C, Norberg K, Mezheyeuski A, Schnittert J, Kuninty P, Moro C, et al. Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC. Br J Cancer. 2017;117:65-77 pubmed publisher
  4. Yang X, Zhao Q, Yin H, Lei X, Gan R. MiR-33b-5p sensitizes gastric cancer cells to chemotherapy drugs via inhibiting HMGA2 expression. J Drug Target. 2017;25:653-660 pubmed publisher
  5. Navarra A, Musto A, Gargiulo A, Petrosino G, Pierantoni G, Fusco A, et al. Hmga2 is necessary for Otx2-dependent exit of embryonic stem cells from the pluripotent ground state. BMC Biol. 2016;14:24 pubmed publisher
  6. Paladino D, Yue P, Furuya H, Acoba J, Rosser C, Turkson J. A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer. Oncotarget. 2016;7:7253-67 pubmed publisher
  7. Gökbuget D, Pereira J, Bachofner S, Marchais A, Ciaudo C, Stoffel M, et al. The Lin28/let-7 axis is critical for myelination in the peripheral nervous system. Nat Commun. 2015;6:8584 pubmed publisher
  8. Galicia Vázquez G, Chu J, Pelletier J. eIF4AII is dispensable for miRNA-mediated gene silencing. RNA. 2015;21:1826-33 pubmed publisher
  9. Madison B, Jeganathan A, Mizuno R, Winslow M, Castells A, Cuatrecasas M, et al. Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2. PLoS Genet. 2015;11:e1005408 pubmed publisher
  10. Suh S, Yoo J, Cui R, Kaur B, Huebner K, Lee T, et al. FHIT suppresses epithelial-mesenchymal transition (EMT) and metastasis in lung cancer through modulation of microRNAs. PLoS Genet. 2014;10:e1004652 pubmed publisher
  11. Li Z, Zhang Y, Ramanujan K, Ma Y, Kirsch D, Glass D. Oncogenic NRAS, required for pathogenesis of embryonic rhabdomyosarcoma, relies upon the HMGA2-IGF2BP2 pathway. Cancer Res. 2013;73:3041-50 pubmed publisher