This is a Validated Antibody Database (VAD) review about mouse Hif1a, based on 193 published articles (read how Labome selects the articles), using Hif1a antibody in all methods. It is aimed to help Labome visitors find the most suited Hif1a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Hif1a synonym: AA959795; HIF-1-alpha; HIF1-alpha; HIF1alpha; MOP1; bHLHe78

Knockout validation
Novus Biologicals
mouse monoclonal (H1alpha67)
  • western blot knockout validation; human; loading ...; fig 5b
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot knockout validation on human samples (fig 5b). Free Radic Biol Med (2019) ncbi
Novus Biologicals
mouse monoclonal (H1alpha67)
  • western blot knockout validation; mouse; loading ...; fig 2f
Novus Biologicals Hif1a antibody (Novus, NB100-123) was used in western blot knockout validation on mouse samples (fig 2f). Nat Commun (2016) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • western blot knockout validation; mouse; fig 3
  • western blot; human; fig 3
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-134) was used in western blot knockout validation on mouse samples (fig 3) and in western blot on human samples (fig 3). Sci Rep (2016) ncbi
Novus Biologicals
mouse monoclonal (H1alpha67)
  • western blot; human; fig 3
  • western blot knockout validation; mouse; fig 3
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on human samples (fig 3) and in western blot knockout validation on mouse samples (fig 3). Sci Rep (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR16897)
  • immunocytochemistry knockout validation; human; 1:100; loading ...; fig 2a
  • western blot knockout validation; human; 1:1000; loading ...; fig 2c
  • immunohistochemistry; human; loading ...; fig 1b
Abcam Hif1a antibody (abcam, ab179483) was used in immunocytochemistry knockout validation on human samples at 1:100 (fig 2a), in western blot knockout validation on human samples at 1:1000 (fig 2c) and in immunohistochemistry on human samples (fig 1b). Cell Death Dis (2021) ncbi
Novus Biologicals
mouse monoclonal (ESEE122)
  • proximity ligation assay; mouse; fig 8a
Novus Biologicals Hif1a antibody (Novus, NB100-131) was used in proximity ligation assay on mouse samples (fig 8a). Cell Mol Life Sci (2022) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; loading ...; fig 5a
  • western blot; rhesus macaque; loading ...; fig 7a, 7b
Novus Biologicals Hif1a antibody (Novus Biological Company, NB100-449) was used in western blot on human samples (fig 5a) and in western blot on rhesus macaque samples (fig 7a, 7b). Aging Dis (2021) ncbi
domestic rabbit polyclonal (OTI2B3)
  • chromatin immunoprecipitation; human; loading ...; fig 1d, s2
Novus Biologicals Hif1a antibody (Novus, NB100-479) was used in chromatin immunoprecipitation on human samples (fig 1d, s2). Sci Adv (2021) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:1000
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on human samples at 1:1000. Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6b
Novus Biologicals Hif1a antibody (Novus, NB100-134) was used in immunohistochemistry - paraffin section on mouse samples (fig 6b). Bone Res (2021) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; rat; 1:1000; loading ...; fig 3a
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-479) was used in western blot on rat samples at 1:1000 (fig 3a). Front Physiol (2021) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; loading ...; fig 6c
Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in western blot on human samples (fig 6c). J Exp Clin Cancer Res (2021) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunohistochemistry; human; 1:100; loading ...; fig s15
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-479) was used in immunohistochemistry on human samples at 1:100 (fig s15). Adv Sci (Weinh) (2021) ncbi
mouse monoclonal (H1alpha67)
  • western blot; mouse; 1:500; loading ...; fig 4c
Novus Biologicals Hif1a antibody (NovusBio, NBP100123) was used in western blot on mouse samples at 1:500 (fig 4c). Cardiovasc Diabetol (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:150; loading ...; fig 5a, 7a
  • immunohistochemistry - paraffin section; human; 1:150; loading ...; fig 5e
Novus Biologicals Hif1a antibody (Novus, NB100-134) was used in immunohistochemistry - paraffin section on mouse samples at 1:150 (fig 5a, 7a) and in immunohistochemistry - paraffin section on human samples at 1:150 (fig 5e). Oncogene (2021) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; 1:1000; loading ...; fig 5, s8a
  • western blot; mouse; 1:1000; loading ...; fig s7a
Novus Biologicals Hif1a antibody (Novus, NB100-479) was used in western blot on human samples at 1:1000 (fig 5, s8a) and in western blot on mouse samples at 1:1000 (fig s7a). Cancer Sci (2021) ncbi
mouse monoclonal (H1alpha67)
  • other; human; 1:50; loading ...; fig 1d
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in other on human samples at 1:50 (fig 1d). Nat Commun (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 8e
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-134) was used in immunohistochemistry on mouse samples at 1:200 (fig 8e). Acta Neuropathol (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 5a
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-134) was used in immunohistochemistry - paraffin section on human samples (fig 5a). J Clin Invest (2020) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; mouse; 1:200; loading ...; fig s4d
Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in immunohistochemistry on mouse samples at 1:200 (fig s4d). Nat Commun (2020) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunohistochemistry; rat; 1:200; loading ...; fig 4a
  • western blot; rat; 1:10,000; loading ...; fig s1a
Novus Biologicals Hif1a antibody (Novus, NB100-479) was used in immunohistochemistry on rat samples at 1:200 (fig 4a) and in western blot on rat samples at 1:10,000 (fig s1a). Int J Mol Med (2020) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:1000; loading ...; fig s13a
Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in western blot on human samples at 1:1000 (fig s13a). Nat Commun (2019) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; domestic rabbit; 1:100; loading ...; fig 7
Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in immunohistochemistry - paraffin section on domestic rabbit samples at 1:100 (fig 7). Kidney Blood Press Res (2019) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; loading ...; fig 3a
Novus Biologicals Hif1a antibody (Novus, NB100-479) was used in western blot on human samples (fig 3a). Nat Commun (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4b
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-134) was used in western blot on mouse samples (fig 4b). Cell Rep (2018) ncbi
mouse monoclonal (H1alpha67)
  • western blot knockout validation; human; loading ...; fig 5b
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot knockout validation on human samples (fig 5b). Free Radic Biol Med (2019) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s4a
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-479) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s4a). Am J Pathol (2018) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry - paraffin section; human; loading ...; fig 10a
  • western blot; human; loading ...; fig 9c
Novus Biologicals Hif1a antibody (Novus Biologics, NB100-131) was used in immunohistochemistry - paraffin section on human samples (fig 10a) and in western blot on human samples (fig 9c). J Clin Invest (2018) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 3a
Novus Biologicals Hif1a antibody (Novus, NB100-449) was used in immunohistochemistry - frozen section on mouse samples (fig 3a). Dis Model Mech (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; fig s4e
Novus Biologicals Hif1a antibody (Novus Biological, NB100-134) was used in western blot on human samples at 1:500 (fig s4e). Nat Cell Biol (2018) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 5e
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry on mouse samples at 1:500 (fig 5e). Nature (2018) ncbi
mouse monoclonal (H1alpha67)
  • western blot; mouse; loading ...; fig 2f
Novus Biologicals Hif1a antibody (Novus, NB100-105SS) was used in western blot on mouse samples (fig 2f). Science (2018) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 2o
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-479) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 2o). Genes Dev (2018) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; 1:500; tbl s1
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-479) was used in western blot on human samples at 1:500 (tbl s1). Stem Cell Reports (2017) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1c
  • western blot; human; 1:600; loading ...; fig 5f
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry - paraffin section on human samples (fig 1c) and in western blot on human samples at 1:600 (fig 5f). J Cell Mol Med (2017) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; mouse; loading ...; fig 3a
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-134) was used in chromatin immunoprecipitation on mouse samples (fig 3a). J Clin Invest (2017) ncbi
mouse monoclonal (H1alpha67)
  • western blot; mouse; loading ...; fig s2a
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on mouse samples (fig s2a). elife (2017) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5c
Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in immunohistochemistry - paraffin section on mouse samples (fig 5c). Cancer Res (2017) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; mouse; 1:500; loading ...; fig s3a
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry on mouse samples at 1:500 (fig s3a). Science (2017) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; mouse; loading ...; fig 5b
In order to report the role of hypoxia inducible factors in myeloid trafficking during inflammation in a mouse model of human uveitis, Novus Biologicals Hif1a antibody (Novus, NB100-449) was used in western blot on mouse samples (fig 5b). Sci Rep (2017) ncbi
domestic rabbit polyclonal (14F468)
  • western blot; mouse; 1:200; loading ...; fig 3a
Novus Biologicals Hif1a antibody (Novus Biologicals, NB-100-654) was used in western blot on mouse samples at 1:200 (fig 3a). Br J Cancer (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1a
In order to define distinct functional subgroups of clear cell renal cell carcinoma based on expression of BAF180, Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-134) was used in western blot on human samples (fig 1a). Oncogenesis (2017) ncbi
mouse monoclonal (H1alpha67)
  • western blot knockout validation; mouse; loading ...; fig 2f
Novus Biologicals Hif1a antibody (Novus, NB100-123) was used in western blot knockout validation on mouse samples (fig 2f). Nat Commun (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunocytochemistry; human; 1:50; loading ...; fig s4a
  • western blot; human; 1:500; loading ...; fig s6
In order to elucidate tumor-derived factors and genetic changes in endothelial cells that contribute to excess centrosomes in tumor endothelial cells, Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in immunocytochemistry on human samples at 1:50 (fig s4a) and in western blot on human samples at 1:500 (fig s6). PLoS ONE (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunoprecipitation; rat; fig 4a
  • western blot; rat; fig 2d
Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in immunoprecipitation on rat samples (fig 4a) and in western blot on rat samples (fig 2d). Am J Transl Res (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; mouse; loading ...; fig 4a
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-479) was used in western blot on mouse samples (fig 4a). Mol Cell Biol (2017) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; mouse; 1:500; loading ...; fig e4a
  • western blot; mouse; 1,000 ug/ml; loading ...; fig 2b
Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in immunohistochemistry on mouse samples at 1:500 (fig e4a) and in western blot on mouse samples at 1,000 ug/ml (fig 2b). Nature (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; 1:1000; loading ...; fig 2c
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-479) was used in western blot on human samples at 1:1000 (fig 2c). Oncotarget (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1). Mol Clin Oncol (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunocytochemistry; mouse; 1:100; fig 1
  • western blot; mouse; 1:500; fig 5
Novus Biologicals Hif1a antibody (Novus Biologicals, H1alpha67) was used in immunocytochemistry on mouse samples at 1:100 (fig 1) and in western blot on mouse samples at 1:500 (fig 5). Sci Rep (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; fig 1B
  • western blot; human; 1:500; fig 1B
Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in immunohistochemistry on human samples (fig 1B) and in western blot on human samples at 1:500 (fig 1B). Front Pharmacol (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1a
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1a). Nat Commun (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 4
Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 4). Theranostics (2016) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig 4f
In order to report that human CD11c positive cells are the main VEGF-A-producing cell population in reactive secondary lymphoid organs, Novus Biologicals Hif1a antibody (Novus Biologicals, NB 10134) was used in chromatin immunoprecipitation on human samples (fig 4f). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; dogs; 1:500; fig 5
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-134) was used in immunohistochemistry - paraffin section on dogs samples at 1:500 (fig 5). Brain Behav (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; mouse; fig 2
Novus Biologicals Hif1a antibody (Novus, NB100-449) was used in western blot on mouse samples (fig 2). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; mouse
Novus Biologicals Hif1a antibody (Novus, NB100-134) was used in chromatin immunoprecipitation on mouse samples . Nat Commun (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; mouse; loading ...; fig 1b
In order to investigate the role of Vhl, Trp53 and Kif3a in renal integrity, Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in immunohistochemistry on mouse samples (fig 1b). J Pathol (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; mouse; loading ...; fig s7a
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-449) was used in western blot on mouse samples (fig s7a). J Clin Invest (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; loading ...; fig 2b
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on human samples (fig 2b). Oncol Lett (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; fig 4
Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in immunohistochemistry on human samples (fig 4). Oncotarget (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunohistochemistry - frozen section; mouse; fig 3
In order to study enhancing mucosal inflammation by chronic ethanol feeding that promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis, Novus Biologicals Hif1a antibody (Novus Biologicals, NB-100-449) was used in immunohistochemistry - frozen section on mouse samples (fig 3). BMC Cancer (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; fig 1
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-479) was used in western blot on human samples (fig 1). Int J Cancer (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; rat; 1:1000; fig 5
Novus Biologicals Hif1a antibody (Novus, NB100-479) was used in western blot on rat samples at 1:1000 (fig 5). Mol Med Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; fig 3
  • western blot; human; fig 3
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-134) was used in western blot knockout validation on mouse samples (fig 3) and in western blot on human samples (fig 3). Sci Rep (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; fig 3
  • western blot knockout validation; mouse; fig 3
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on human samples (fig 3) and in western blot knockout validation on mouse samples (fig 3). Sci Rep (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; fig 2a
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-479) was used in western blot on human samples (fig 2a). Cancer Res (2016) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; 1:200; loading ...; fig 2f
  • western blot; human; 1:1000; loading ...; fig 2f
In order to discuss the contribution of LINK-A to cancer, Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-134) was used in immunoprecipitation on human samples at 1:200 (fig 2f) and in western blot on human samples at 1:1000 (fig 2f). Nat Cell Biol (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:500; fig 3
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on human samples at 1:500 (fig 3). J Cell Sci (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:500; fig 3a
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on human samples at 1:500 (fig 3a). Cell Tissue Res (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:500
In order to report the contribution of DYRK1A and DYRK1B in cancer stem cells, Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on human samples at 1:500. Nature (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; 1:100; loading ...; fig 2b
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry on human samples at 1:100 (fig 2b). Oncotarget (2016) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; mouse; 1:200; fig s5
Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s5). Cancer Sci (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 1
Novus Biologicals Hif1a antibody (Novus, NB100-134) was used in western blot on human samples (fig 1). J Cell Mol Med (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunocytochemistry; human; 1:100; fig 4
  • western blot; human; 1:500; fig 3
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-479) was used in immunocytochemistry on human samples at 1:100 (fig 4) and in western blot on human samples at 1:500 (fig 3). Oncol Rep (2016) ncbi
domestic rabbit polyclonal
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-134) was used . Nucleic Acids Res (2015) ncbi
domestic rabbit polyclonal (OTI2B3)
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-449) was used . Antioxid Redox Signal (2015) ncbi
domestic rabbit polyclonal (OTI2B3)
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-479) was used . PLoS ONE (2015) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry - paraffin section; human; fig 2
Novus Biologicals Hif1a antibody (Novus Biologicals, ESEE122) was used in immunohistochemistry - paraffin section on human samples (fig 2). J Cancer (2015) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:2000
Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in western blot on human samples at 1:2000. Life Sci (2015) ncbi
mouse monoclonal (H1alpha67)
  • ELISA; human; fig s4
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in ELISA on human samples (fig s4). PLoS ONE (2015) ncbi
domestic rabbit polyclonal (OTI2B3)
In order to investigate how PHD2 and PHD3 modulate contractile function, Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-479) was used . J Clin Invest (2015) ncbi
domestic rabbit polyclonal
In order to assess the effect of low-level light irradiation prior to transplantation of adipose-derived stromal cell spheroids on a skin wound model, Novus Biologicals Hif1a antibody (Novus, NB100-134) was used . PLoS ONE (2015) ncbi
domestic rabbit polyclonal (OTI2B3)
In order to investigate the effects of prior treatment of simvastatin on mitochondrial enzyme, ghrelin, and hypoxia-inducible factor 1 alpha in septic rats, Novus Biologicals Hif1a antibody (Novus, NB100-479) was used . Int J Clin Exp Med (2015) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; mouse
  • western blot; human; 1:500
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry on mouse samples and in western blot on human samples at 1:500. Sci Rep (2015) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; loading ...; fig 3a
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on human samples (fig 3a). Int J Biol Sci (2015) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; fig 4c
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on human samples (fig 4c). Int J Mol Med (2015) ncbi
domestic rabbit polyclonal (OTI2B3)
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-449) was used . Nat Commun (2015) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; fig 1
Novus Biologicals Hif1a antibody (Biologicals, NB100-105) was used in western blot on human samples (fig 1). Nucleic Acids Res (2015) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; tbl 2
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on human samples (tbl 2). PLoS ONE (2015) ncbi
domestic rabbit polyclonal
Novus Biologicals Hif1a antibody (Novus, NB100-134) was used . Nat Commun (2015) ncbi
domestic rabbit polyclonal (OTI2B3)
In order to describe the multiple lentiviral expression (MuLE) system that allows multiple genetic alterations to be introduced simultaneously into mammalian cells, Novus Biologicals Hif1a antibody (Novus, NB100-479) was used . J Clin Invest (2015) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry; human
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-131) was used in immunohistochemistry on human samples . Acta Neuropathol Commun (2014) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:600
  • western blot; rat
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-134) was used in western blot on mouse samples at 1:600 and in western blot on rat samples . Mol Neurobiol (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot; mouse
In order to identify DUBA as a suppressor of IL-17 production in T cells, Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in western blot on mouse samples . Nature (2015) ncbi
domestic rabbit polyclonal (OTI2B3)
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-479) was used . Neurosci Lett (2015) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - frozen section; rat; 1:200; loading ...; fig s2
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in immunohistochemistry - frozen section on rat samples at 1:200 (fig s2). J Cell Biochem (2015) ncbi
mouse monoclonal (H1alpha67)
  • western blot; mouse; 1:1000
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on mouse samples at 1:1000. Neuroreport (2014) ncbi
mouse monoclonal (ESEE122)
  • western blot; mouse; 1:2000; fig 2
In order to study vascular endothelial growth factor signaling in mice infected with Plasmodium berghei ANKA, Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-131A1) was used in western blot on mouse samples at 1:2000 (fig 2). Front Immunol (2014) ncbi
mouse monoclonal (H1alpha67)
  • immunocytochemistry; rat; 1:200
Novus Biologicals Hif1a antibody (Novus Biological, NB-100-123) was used in immunocytochemistry on rat samples at 1:200. Acta Neuropathol Commun (2014) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; loading ...; fig 6c
Novus Biologicals Hif1a antibody (Novus, NB100-105) was used in immunohistochemistry on human samples (fig 6c). Nucleic Acids Res (2014) ncbi
mouse monoclonal (H1alpha67)
  • western blot; rat
Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on rat samples . J Biol Chem (2013) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human
Novus Biologicals Hif1a antibody (Novus, NB100-123) was used in western blot on human samples . Cell Cycle (2012) ncbi
mouse monoclonal (H1alpha67)
  • western blot; rat
In order to study the role of low-level laser therapy in neuropathic pain alleviation and recovery from chronic constriction injury, Novus Biologicals Hif1a antibody (Novus Biologicals, NB100-105) was used in western blot on rat samples . J Comp Neurol (2012) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; human; 1:200
  • immunohistochemistry; human
Novus Biologicals Hif1a antibody (Novus Biologicals, NB 100-105) was used in immunohistochemistry - paraffin section on human samples at 1:200 and in immunohistochemistry on human samples . J Histochem Cytochem (2007) ncbi
Abcam
domestic rabbit monoclonal (EPR16897)
  • immunohistochemistry; mouse; loading ...; fig s1j
Abcam Hif1a antibody (Abcam, ab179483) was used in immunohistochemistry on mouse samples (fig s1j). Sci Rep (2022) ncbi
mouse monoclonal (H1alpha67)
  • chromatin immunoprecipitation; human; loading ...; fig 3e
Abcam Hif1a antibody (Abcam, ab1) was used in chromatin immunoprecipitation on human samples (fig 3e). Nat Commun (2022) ncbi
domestic rabbit monoclonal (EPR16897)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 7a
Abcam Hif1a antibody (Abcam, ab179483) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 7a). Mol Med Rep (2022) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:3000; loading ...; fig 4d
Abcam Hif1a antibody (Abcam, ab1) was used in western blot on human samples at 1:3000 (fig 4d). Oncol Lett (2021) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; rat; 1:100; fig 3c
Abcam Hif1a antibody (Abcam, ab1) was used in immunohistochemistry on rat samples at 1:100 (fig 3c). J Tissue Eng (2021) ncbi
domestic rabbit monoclonal (EPR16897)
  • immunohistochemistry - paraffin section; mouse; 1:250; loading ...; fig s2
  • western blot; mouse; 1:1000; fig 3a
Abcam Hif1a antibody (Abcam, ab179483) was used in immunohistochemistry - paraffin section on mouse samples at 1:250 (fig s2) and in western blot on mouse samples at 1:1000 (fig 3a). Aging (Albany NY) (2021) ncbi
domestic rabbit monoclonal (EPR16897)
  • immunocytochemistry knockout validation; human; 1:100; loading ...; fig 2a
  • western blot knockout validation; human; 1:1000; loading ...; fig 2c
  • immunohistochemistry; human; loading ...; fig 1b
Abcam Hif1a antibody (abcam, ab179483) was used in immunocytochemistry knockout validation on human samples at 1:100 (fig 2a), in western blot knockout validation on human samples at 1:1000 (fig 2c) and in immunohistochemistry on human samples (fig 1b). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (EPR16897)
  • western blot; mouse; loading ...; fig 3e, 3f
Abcam Hif1a antibody (Abcam, ab179483) was used in western blot on mouse samples (fig 3e, 3f). EMBO J (2021) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:500; fig 5d
Abcam Hif1a antibody (Abcam Technology, ab1) was used in western blot on human samples at 1:500 (fig 5d). Oncogene (2021) ncbi
mouse monoclonal (H1alpha67)
  • chromatin immunoprecipitation; human; loading ...; fig 3k
Abcam Hif1a antibody (Abcam, ab1) was used in chromatin immunoprecipitation on human samples (fig 3k). Cell Death Dis (2020) ncbi
domestic rabbit monoclonal (EPR16897)
  • immunohistochemistry; rat; 1:50; loading ...; fig 5c
Abcam Hif1a antibody (Abcam, ab179483) was used in immunohistochemistry on rat samples at 1:50 (fig 5c). Cell Prolif (2020) ncbi
domestic rabbit monoclonal (EPR16897)
  • western blot; mouse; loading ...; fig 5c
Abcam Hif1a antibody (Abcam, ab179483) was used in western blot on mouse samples (fig 5c). Cell (2019) ncbi
domestic rabbit monoclonal (EPR16897)
  • western blot; human; loading ...; fig s6d
Abcam Hif1a antibody (Abcam, 179483) was used in western blot on human samples (fig s6d). J Clin Invest (2019) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; 1:100; loading ...; fig 6a
Abcam Hif1a antibody (Abcam, ab1) was used in immunohistochemistry on human samples at 1:100 (fig 6a). Nature (2018) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry - frozen section; mouse; fig 1d
Abcam Hif1a antibody (Abcam, ab8366) was used in immunohistochemistry - frozen section on mouse samples (fig 1d). J Clin Invest (2018) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry - frozen section; human; 1:100; loading ...; fig 7b
Abcam Hif1a antibody (Abcam, ab8366) was used in immunohistochemistry - frozen section on human samples at 1:100 (fig 7b). J Histochem Cytochem (2018) ncbi
mouse monoclonal (H1alpha67)
  • immunocytochemistry; human; 1:200; loading ...; fig 1e
  • western blot; human; loading ...; fig 1d
Abcam Hif1a antibody (Abcam, ab1) was used in immunocytochemistry on human samples at 1:200 (fig 1e) and in western blot on human samples (fig 1d). Stem Cells Dev (2017) ncbi
domestic rabbit monoclonal (EPR16897)
  • immunohistochemistry - frozen section; mouse; fig s6e
In order to demonstrate that type 1 T helper cells play a crucial role in vessel normalization, Abcam Hif1a antibody (Abcam, EPR16897) was used in immunohistochemistry - frozen section on mouse samples (fig s6e). Nature (2017) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry - paraffin section; human; 1:250; loading ...; fig 2
In order to test if BiP and CHOP expressions correlate with pre-malignant lesion progression, Abcam Hif1a antibody (Abcam, ab8366) was used in immunohistochemistry - paraffin section on human samples at 1:250 (fig 2). Virchows Arch (2016) ncbi
mouse monoclonal (H1alpha67)
  • chromatin immunoprecipitation; mouse; loading ...; fig 6g
In order to research the atheroprotective effect of OCT4 in smooth muscle cells, Abcam Hif1a antibody (Abcam, ab1) was used in chromatin immunoprecipitation on mouse samples (fig 6g). Nat Med (2016) ncbi
mouse monoclonal (ESEE122)
  • immunocytochemistry; human; fig 1
Abcam Hif1a antibody (Abcam, ab8366) was used in immunocytochemistry on human samples (fig 1). J Diabetes Res (2016) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry - paraffin section; human; loading ...; tbl 4
Abcam Hif1a antibody (Abcam, ESEE122) was used in immunohistochemistry - paraffin section on human samples (tbl 4). Chin J Cancer (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot; mouse; loading ...; fig 1a
Abcam Hif1a antibody (Abcam, ab1) was used in western blot on mouse samples (fig 1a). PLoS ONE (2015) ncbi
mouse monoclonal (ESEE122)
  • western blot; human; 1:1000; fig 3
In order to discuss the consequences of Diabetes Associated Protein in Insulin-sensitive Tissues overexpression, Abcam Hif1a antibody (Abcam, ab8366) was used in western blot on human samples at 1:1000 (fig 3). PLoS ONE (2015) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry; human; 1:500; fig 6c
Abcam Hif1a antibody (Abcam, ab8366) was used in immunohistochemistry on human samples at 1:500 (fig 6c). Oncotarget (2015) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human
Abcam Hif1a antibody (Abcam, ab1) was used in western blot on human samples . Br J Pharmacol (2015) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; 1:500
In order to identify genetic alterations and corresponding stable phenotypes that develop in cancer cells following cyclic hypoxia, Abcam Hif1a antibody (Abcam, ab1) was used in immunohistochemistry on human samples at 1:500. PLoS ONE (2015) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; human; 1:200
  • western blot; human; 1:5000
Abcam Hif1a antibody (Abcam, ab1) was used in immunohistochemistry - paraffin section on human samples at 1:200 and in western blot on human samples at 1:5000. Stem Cells (2014) ncbi
mouse monoclonal (ESEE122)
  • western blot; rat; 1:1000
Abcam Hif1a antibody (Abcam, ab8366) was used in western blot on rat samples at 1:1000. Cell Signal (2014) ncbi
mouse monoclonal (H1alpha67)
  • western blot; rat; 1:200
In order to study HIF-1alpha mediated metabolic switching and mitochondrial remodeling in bladder outlet obstruction, Abcam Hif1a antibody (Abcam, H1alpha67) was used in western blot on rat samples at 1:200. Lab Invest (2014) ncbi
mouse monoclonal (ESEE122)
  • immunohistochemistry - paraffin section; rat; 1:100
Abcam Hif1a antibody (Abcam, ab8366) was used in immunohistochemistry - paraffin section on rat samples at 1:100. Stem Cells Dev (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H1alpha 67)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 6e
  • western blot; human; 1:2000; loading ...; fig 6h
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-53546) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 6e) and in western blot on human samples at 1:2000 (fig 6h). Front Oncol (2022) ncbi
mouse monoclonal (28b)
  • chromatin immunoprecipitation; human; loading ...; fig 10e
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-13515) was used in chromatin immunoprecipitation on human samples (fig 10e). Theranostics (2021) ncbi
mouse monoclonal (H1alpha 67)
  • immunocytochemistry; mouse; 1:80; loading ...; fig 5a
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-53546) was used in immunocytochemistry on mouse samples at 1:80 (fig 5a). Biomolecules (2020) ncbi
mouse monoclonal (28b)
  • western blot; human; 1:300; loading ...; fig 6a
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-13515) was used in western blot on human samples at 1:300 (fig 6a). PLoS ONE (2020) ncbi
mouse monoclonal (28b)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 4e
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, 28b) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 4e). Chin Med J (Engl) (2020) ncbi
mouse monoclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 4e
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, 28b) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 4e). Chin Med J (Engl) (2020) ncbi
mouse monoclonal (28b)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 5a
  • western blot; mouse; loading ...; fig 4g
Santa Cruz Biotechnology Hif1a antibody (Santa, sc-13515) was used in immunohistochemistry on mouse samples at 1:100 (fig 5a) and in western blot on mouse samples (fig 4g). Invest Ophthalmol Vis Sci (2019) ncbi
mouse monoclonal (28b)
  • immunohistochemistry - paraffin section; human; 1:50; fig 2a
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, 28b) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 2a). Arch Med Sci (2017) ncbi
mouse monoclonal
  • immunohistochemistry - paraffin section; human; 1:50; fig 2a
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, 28b) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 2a). Arch Med Sci (2017) ncbi
mouse monoclonal (28b)
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-13515) was used in western blot on human samples (fig 2a). Am J Transl Res (2017) ncbi
mouse monoclonal (28b)
  • western blot; human; 1:500; loading ...; fig 3A
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-13515) was used in western blot on human samples at 1:500 (fig 3A). Oncol Lett (2017) ncbi
mouse monoclonal (28b)
  • immunohistochemistry; human; fig 1e
In order to describe a function for NQO1 in stabilizing HIF-1alpha, Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-13515) was used in immunohistochemistry on human samples (fig 1e). Nat Commun (2016) ncbi
mouse monoclonal (H1alpha 67)
  • western blot; human; loading ...; fig 9d
In order to assess the anticancer properties of 3',4',5'-trimethoxy-5-chloro-isatinylchalcone, Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, H1alpha 67) was used in western blot on human samples (fig 9d). PLoS ONE (2016) ncbi
mouse monoclonal (H1alpha 67)
  • immunocytochemistry; human; 1:50; fig 2
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-53546) was used in immunocytochemistry on human samples at 1:50 (fig 2). Oncol Lett (2016) ncbi
mouse monoclonal (H1alpha 67)
  • immunohistochemistry - paraffin section; mouse; 1:25; fig 3
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, 67) was used in immunohistochemistry - paraffin section on mouse samples at 1:25 (fig 3). Stem Cells Int (2016) ncbi
mouse monoclonal (3C144)
  • western blot; mouse; 1:1000; loading ...; fig 2a
In order to examine the effects of hypoxia on glucose transporters expressed by astrocytes, Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-71247) was used in western blot on mouse samples at 1:1000 (fig 2a). Mol Med Rep (2016) ncbi
mouse monoclonal (H1alpha 67)
  • immunohistochemistry - paraffin section; human; 1:20; fig 1
In order to characterize aggressive tumors in African breast cancer and the strong expression of hypoxia-inducible factor-1 alpha (HIF-1alpha) and its association with Axl expression, Santa Cruz Biotechnology Hif1a antibody (Santa Cruz Biotechnology, sc-53546) was used in immunohistochemistry - paraffin section on human samples at 1:20 (fig 1). PLoS ONE (2016) ncbi
mouse monoclonal (28b)
  • immunoprecipitation; human; 1:200; loading ...; fig 2f
  • western blot; human; 1:1000; loading ...; fig 2f
In order to discuss the contribution of LINK-A to cancer, Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-13515) was used in immunoprecipitation on human samples at 1:200 (fig 2f) and in western blot on human samples at 1:1000 (fig 2f). Nat Cell Biol (2016) ncbi
mouse monoclonal (H1alpha 67)
  • immunoprecipitation; human; 1:1000; fig 5
  • western blot; human; 1:1000; fig 4
In order to investigate factors that control PHD1 activity, Santa Cruz Biotechnology Hif1a antibody (Santa Cruz Biotechnology, sc-53546) was used in immunoprecipitation on human samples at 1:1000 (fig 5) and in western blot on human samples at 1:1000 (fig 4). J Cell Sci (2016) ncbi
mouse monoclonal (28b)
  • western blot; human; 1:500; fig 1
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-13515) was used in western blot on human samples at 1:500 (fig 1). Mol Med Rep (2015) ncbi
mouse monoclonal (28b)
  • immunocytochemistry; human; fig 4
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-13515) was used in immunocytochemistry on human samples (fig 4). PLoS ONE (2015) ncbi
mouse monoclonal (3C144)
  • western blot; human
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-71247) was used in western blot on human samples . PLoS ONE (2015) ncbi
mouse monoclonal (H1alpha 67)
  • western blot; human; fig 3
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-53546) was used in western blot on human samples (fig 3). EBioMedicine (2015) ncbi
mouse monoclonal (28b)
  • immunohistochemistry - paraffin section; human; 1:200; fig 1
  • western blot; human; 1:1000; fig 1
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-13515) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1) and in western blot on human samples at 1:1000 (fig 1). Oncotarget (2015) ncbi
mouse monoclonal (28b)
  • immunohistochemistry - paraffin section; human; fig 4
  • western blot; human; loading ...; fig 3
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz Biotechnology, sc-13515) was used in immunohistochemistry - paraffin section on human samples (fig 4) and in western blot on human samples (fig 3). Mol Med Rep (2015) ncbi
mouse monoclonal (28b)
  • immunohistochemistry - paraffin section; human; fig 4
  • western blot; human; fig 4
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz Biotechnology, sc-13515) was used in immunohistochemistry - paraffin section on human samples (fig 4) and in western blot on human samples (fig 4). PLoS ONE (2015) ncbi
mouse monoclonal (H1alpha 67)
  • western blot; human; fig 3
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-53546) was used in western blot on human samples (fig 3). Oncotarget (2015) ncbi
mouse monoclonal (H1alpha 67)
  • western blot; human; 1:500; fig 1
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz, sc-53546) was used in western blot on human samples at 1:500 (fig 1). Mol Med Rep (2015) ncbi
mouse monoclonal (H1alpha 67)
  • immunocytochemistry; human; 1:50; fig 4
In order to identify PITX1 as a key specificity factor for HIF-1alpha dependent gene expression, Santa Cruz Biotechnology Hif1a antibody (anta Cruz, sc-53546) was used in immunocytochemistry on human samples at 1:50 (fig 4). Cell Cycle (2014) ncbi
mouse monoclonal (H1alpha 67)
  • western blot; human
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz Biotechnology, sc-53546) was used in western blot on human samples . Oncotarget (2015) ncbi
mouse monoclonal (H1alpha 67)
  • immunohistochemistry - paraffin section; human; loading ...; fig 4
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz Biotechnology, sc-53546) was used in immunohistochemistry - paraffin section on human samples (fig 4). Front Physiol (2014) ncbi
mouse monoclonal (H1alpha 67)
  • immunohistochemistry; rat; 1:100
  • western blot; rat; 1:2000
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz Biotechnology, sc-53546) was used in immunohistochemistry on rat samples at 1:100 and in western blot on rat samples at 1:2000. Br J Neurosurg (2014) ncbi
mouse monoclonal (28b)
  • EMSA; human; 1 ug
Santa Cruz Biotechnology Hif1a antibody (Santa-Cruz Biotechnology Inc., sc13515) was used in EMSA on human samples at 1 ug. Liver Int (2015) ncbi
mouse monoclonal (H1alpha 67)
  • western blot; rat
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz Biotechnology, sc-53546) was used in western blot on rat samples . Vascular (2015) ncbi
mouse monoclonal (H1alpha 67)
  • western blot; rat
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz Biotechnology, sc-53546) was used in western blot on rat samples . PLoS ONE (2014) ncbi
mouse monoclonal (H1alpha 67)
  • immunohistochemistry - paraffin section; human; 1:50; tbl 1
In order to measure the expression of VEGF, HIF-1alpha, and CD34 in breast tumors and correlate the findings with clinical and pathological variables, Santa Cruz Biotechnology Hif1a antibody (Santa Cruz Biotechnology, clone H1alpha67) was used in immunohistochemistry - paraffin section on human samples at 1:50 (tbl 1). Acta Histochem (2014) ncbi
mouse monoclonal (H1alpha 67)
  • immunohistochemistry - paraffin section; human; 1:100
Santa Cruz Biotechnology Hif1a antibody (Santa Cruz Biotechnology, sc-53546) was used in immunohistochemistry - paraffin section on human samples at 1:100. Brain Tumor Pathol (2014) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1b
In order to determine the effect of ginsenoside Rg5 on adipose dysfunction and muscle insulin resistance, Invitrogen Hif1a antibody (Thermo Scientific, PA1-16601) was used in western blot on mouse samples at 1:1000 (fig 1b). Front Pharmacol (2017) ncbi
mouse monoclonal (mgc3)
  • immunocytochemistry; mouse; 1:200; fig s1a
In order to ask whether PrP+ cTnT+ cells are present in the human heart tissue with myocardial infarction, Invitrogen Hif1a antibody (Pierce, MA1-516) was used in immunocytochemistry on mouse samples at 1:200 (fig s1a). Sci Rep (2017) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; loading ...; fig 1b
In order to define distinct functional subgroups of clear cell renal cell carcinoma based on expression of BAF180, Invitrogen Hif1a antibody (Thermo Fisher Scientific, H1alpha67) was used in immunohistochemistry on human samples (fig 1b). Oncogenesis (2017) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; pigs ; 1:1000; loading ...; tbl 1
In order to analyze oxidative stress markers after remote ischemic preconditioning in pig., Invitrogen Hif1a antibody (NeoMarkers, Ab-4) was used in immunohistochemistry on pigs samples at 1:1000 (tbl 1). Semin Thorac Cardiovasc Surg (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 3
In order to characterize prevention of lipolysis and inflammation in hypoxic adipose tissue by studying metformin and resveratrol that ameliorate muscle insulin resistance, Invitrogen Hif1a antibody (Thermo Fisher Scientific, PA1-16601) was used in western blot on mouse samples (fig 3). Cell Signal (2016) ncbi
mouse monoclonal (mgc3)
  • western blot; human; loading ...; fig 1a
In order to propose that HIF-2-alpha is a negative regulator of estrogen receptor expression in breast cancer, Invitrogen Hif1a antibody (Affinity Bioreagents, mgc3) was used in western blot on human samples (fig 1a). FEBS Lett (2016) ncbi
mouse monoclonal (H1alpha67)
  • western blot; human; 1:1000; fig 1
In order to characterize the association with RASAL1 promoter hypermethylation in human coronary endothelial cells and hypoxia-induced endothelial-mesenchymal transition, Invitrogen Hif1a antibody (Thermo Scientific, MA1-16504) was used in western blot on human samples at 1:1000 (fig 1). FEBS Lett (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 9a
In order to test if nicotinamide adenosine diphosphate oxidase 2 contributes to cyclosporine A-induced chronic hypoxia, Invitrogen Hif1a antibody (Thermo Fisher, PA3-16521) was used in western blot on mouse samples at 1:500 (fig 9a). Transplantation (2016) ncbi
domestic rabbit polyclonal
In order to elucidate the contributions of low oxygen in fracture healing impairment, Invitrogen Hif1a antibody (ThermoFisher Scientific, PA1-16601) was used . Mol Med Rep (2015) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; human; 1:200
Invitrogen Hif1a antibody (LabVision, H1alpha67) was used in immunohistochemistry on human samples at 1:200. Int Urol Nephrol (2015) ncbi
domestic rabbit polyclonal
In order to demonstrate that coumaric acid is protective after a ischemia-reperfusion injury of the spinal cord, Invitrogen Hif1a antibody (Thermo Fisher Scientific, PA1-16601) was used . Inflammation (2015) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry - paraffin section; human; 1:50
In order to correlate 18-F-fluoro-deoxyglucose uptake and aggressive tumor biology in predicting outcome in esophageal cancer, Invitrogen Hif1a antibody (Neomarkers, MS-1164) was used in immunohistochemistry - paraffin section on human samples at 1:50. Ann Surg Oncol (2014) ncbi
mouse monoclonal (mgc3)
  • EMSA; mouse
  • EMSA; rat
In order to study the upregulation of pancreatic beta cell ARAP1 by a functional regulatory DNA variant at a type 2 diabetes locus, Invitrogen Hif1a antibody (Thermo Scientific, MA1-516) was used in EMSA on mouse samples and in EMSA on rat samples . Am J Hum Genet (2014) ncbi
mouse monoclonal (H1alpha67)
  • immunohistochemistry; rat; 1:200
In order to study the role of low-level laser therapy in neuropathic pain alleviation and recovery from chronic constriction injury, Invitrogen Hif1a antibody (Thermo, MS-1164-P0) was used in immunohistochemistry on rat samples at 1:200. J Comp Neurol (2012) ncbi
R&D Systems
domestic goat polyclonal
  • western blot; human; loading ...; fig 4e, 5e
R&D Systems Hif1a antibody (R&D Systems, AF1935) was used in western blot on human samples (fig 4e, 5e). Cancer Cell Int (2021) ncbi
domestic goat polyclonal
  • immunocytochemistry; human; 1:20; loading ...; fig s4
R&D Systems Hif1a antibody (R&D Systems, AF1935) was used in immunocytochemistry on human samples at 1:20 (fig s4). Commun Biol (2021) ncbi
SICGEN
domestic goat polyclonal
In order to report that K63 ubiquitination is required for chaperone-mediated autophagy degradation of HIF1A in vitro and in vivo, SICGEN Hif1a antibody (Sicgen, AB0112-200) was used . Sci Rep (2015) ncbi
Active Motif
mouse monoclonal (ESEE122)
  • western blot; human; 1:1000; fig 4
Active Motif Hif1a antibody (Active Motif, 61275) was used in western blot on human samples at 1:1000 (fig 4). Oncotarget (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D43B5)
  • western blot; human; 1:1000; loading ...; fig 3d
  • western blot; mouse; 1:1000; loading ...; fig 3d
Cell Signaling Technology Hif1a antibody (Cell Signaling, 3434) was used in western blot on human samples at 1:1000 (fig 3d) and in western blot on mouse samples at 1:1000 (fig 3d). Oncogene (2021) ncbi
domestic rabbit monoclonal (D43B5)
  • western blot; human; 1:1000; loading ...; fig s6b
Cell Signaling Technology Hif1a antibody (Cell Signaling, 3434) was used in western blot on human samples at 1:1000 (fig s6b). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (D43B5)
  • western blot; human; 1:1000; loading ...; fig 7c
Cell Signaling Technology Hif1a antibody (Cell Signaling, 3434) was used in western blot on human samples at 1:1000 (fig 7c). Hypoxia (Auckl) (2019) ncbi
domestic rabbit monoclonal (D43B5)
  • western blot; human; 1:500; loading ...; fig 4b
Cell Signaling Technology Hif1a antibody (Cell Signaling, 3434) was used in western blot on human samples at 1:500 (fig 4b). Nat Commun (2019) ncbi
domestic rabbit monoclonal (D43B5)
  • western blot; human; loading ...; fig 8e
Cell Signaling Technology Hif1a antibody (Cell Signaling Technology, 3434) was used in western blot on human samples (fig 8e). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (D43B5)
  • immunohistochemistry - frozen section; mouse; fig s3g
Cell Signaling Technology Hif1a antibody (Cell Signaling, D43B5) was used in immunohistochemistry - frozen section on mouse samples (fig s3g). Science (2017) ncbi
domestic rabbit monoclonal (D43B5)
  • western blot; human; 1:2000; loading ...; fig 7E
In order to identify cellular processes that regulate HIF1alpha, Cell Signaling Technology Hif1a antibody (Cell signaling, 3434) was used in western blot on human samples at 1:2000 (fig 7E). elife (2017) ncbi
domestic rabbit monoclonal (D43B5)
  • western blot; mouse; 1:1000
Cell Signaling Technology Hif1a antibody (Cell Signaling, 3434S) was used in western blot on mouse samples at 1:1000. Sci Transl Med (2016) ncbi
domestic rabbit monoclonal (D43B5)
  • western blot; human; 1:5000; fig s1
Cell Signaling Technology Hif1a antibody (Cell Signaling Technology, 3434) was used in western blot on human samples at 1:5000 (fig s1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D43B5)
  • western blot; human; 1:1000; loading ...; fig 4g
In order to discuss the contribution of LINK-A to cancer, Cell Signaling Technology Hif1a antibody (Cell Signaling, 3434) was used in western blot on human samples at 1:1000 (fig 4g). Nat Cell Biol (2016) ncbi
domestic rabbit monoclonal (D43B5)
  • western blot; human; 1:1000; fig 4
In order to investigate factors that control PHD1 activity, Cell Signaling Technology Hif1a antibody (Cell Signaling, 3434) was used in western blot on human samples at 1:1000 (fig 4). J Cell Sci (2016) ncbi
domestic rabbit monoclonal (D43B5)
  • western blot; human; 1:500; fig 3
Cell Signaling Technology Hif1a antibody (Cell Signaling, 3434S) was used in western blot on human samples at 1:500 (fig 3). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D43B5)
  • immunoprecipitation; human; fig 8
Cell Signaling Technology Hif1a antibody (Cell signaling, D43B5) was used in immunoprecipitation on human samples (fig 8). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D43B5)
  • western blot; human; 1:1000
In order to study the effect of allopurinol treatment during hypoxia, Cell Signaling Technology Hif1a antibody (Cell Signaling Technology, 3434) was used in western blot on human samples at 1:1000. PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D43B5)
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology Hif1a antibody (Cell Signaling, 3434) was used in western blot on human samples at 1:1000 (fig 3). Nat Cell Biol (2015) ncbi
domestic rabbit monoclonal (D43B5)
  • western blot; human; fig 2a
In order to elucidate how EglN2 regulates FOXO3a degradation, Cell Signaling Technology Hif1a antibody (Cell Signaling, 3434) was used in western blot on human samples (fig 2a). Genes Dev (2014) ncbi
BD Biosciences
mouse monoclonal (29/HIF-1b)
  • western blot; human; fig 1f
BD Biosciences Hif1a antibody (BD Laboratories, 611078) was used in western blot on human samples (fig 1f). Cell Rep (2021) ncbi
mouse monoclonal (29/HIF-1b)
  • western blot; human; fig 1e
In order to find compounds that are synthetically lethal with von Hippel-Lindau deficiency in clear cell renal cell carcinoma, BD Biosciences Hif1a antibody (BD Biosciences, 611078) was used in western blot on human samples (fig 1e). Oncogene (2017) ncbi
mouse monoclonal (29/HIF-1b)
  • western blot; mouse; fig 3
BD Biosciences Hif1a antibody (BD, 611078) was used in western blot on mouse samples (fig 3). Toxicol Sci (2015) ncbi
mouse monoclonal (29/HIF-1b)
  • western blot; human; fig 4a
In order to elucidate how EglN2 regulates FOXO3a degradation, BD Biosciences Hif1a antibody (BD, 611079) was used in western blot on human samples (fig 4a). Genes Dev (2014) ncbi
Articles Reviewed
  1. Pandey S, Shteinfer Kuzmine A, Chalifa Caspi V, Shoshan Barmatz V. Non-apoptotic activity of the mitochondrial protein SMAC/Diablo in lung cancer: Novel target to disrupt survival, inflammation, and immunosuppression. Front Oncol. 2022;12:992260 pubmed publisher
  2. Yoshida Y, Shimizu I, Shimada A, Nakahara K, Yanagisawa S, Kubo M, et al. Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism. Sci Rep. 2022;12:14883 pubmed publisher
  3. Ka N, Lim G, Kim S, Hwang S, Han J, Lee Y, et al. Type I IFN stimulates IFI16-mediated aromatase expression in adipocytes that promotes E2-dependent growth of ER-positive breast cancer. Cell Mol Life Sci. 2022;79:306 pubmed publisher
  4. Zhang M, Cui J, Lee D, Yuen V, Chiu D, Goh C, et al. Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer. Nat Commun. 2022;13:954 pubmed publisher
  5. Méndez Solís O, Bendjennat M, Naipauer J, Theodoridis P, Ho J, Verdun R, et al. Kaposi's sarcoma herpesvirus activates the hypoxia response to usurp HIF2α-dependent translation initiation for replication and oncogenesis. Cell Rep. 2021;37:110144 pubmed publisher
  6. Yeh C, Liu H, Lee M, Leu Y, Chiang W, Chang H, et al. Phytochemical‑rich herbal formula ATG‑125 protects against sucrose‑induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice. Mol Med Rep. 2022;25: pubmed publisher
  7. Sil S, Singh S, Chemparathy D, Chivero E, Gordon L, Buch S. Astrocytes & Astrocyte derived Extracellular Vesicles in Morphine Induced Amyloidopathy: Implications for Cognitive Deficits in Opiate Abusers. Aging Dis. 2021;12:1389-1408 pubmed publisher
  8. Wang Y, Lyu Y, Tu K, Xu Q, Yang Y, Salman S, et al. Histone citrullination by PADI4 is required for HIF-dependent transcriptional responses to hypoxia and tumor vascularization. Sci Adv. 2021;7: pubmed publisher
  9. Tang X, Li G, Shi L, Su F, Qian M, Liu Z, et al. Combined intermittent fasting and ERK inhibition enhance the anti-tumor effects of chemotherapy via the GSK3β-SIRT7 axis. Nat Commun. 2021;12:5058 pubmed publisher
  10. Wu Q, Zhang W, Liu Y, Huang Y, Wu H, Ma C. Histone deacetylase 1 facilitates aerobic glycolysis and growth of endometrial cancer. Oncol Lett. 2021;22:721 pubmed publisher
  11. Han E, Wang J, Kural M, Jiang B, Leiby K, Chowdhury N, et al. Development of a Bioartificial Vascular Pancreas. J Tissue Eng. 2021;12:20417314211027714 pubmed publisher
  12. Shao R, Zhang Z, Xu Z, Ouyang H, Wang L, Ouyang H, et al. H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair. Bone Res. 2021;9:30 pubmed publisher
  13. Wang N, Peng Y, Su X, Prabhakar N, Nanduri J. Histone Deacetylase 5 Is an Early Epigenetic Regulator of Intermittent Hypoxia Induced Sympathetic Nerve Activation and Blood Pressure. Front Physiol. 2021;12:688322 pubmed publisher
  14. Pan W, Song X, Hu Q, Zhang Y. miR-485 inhibits histone deacetylase HDAC5, HIF1α and PFKFB3 expression to alleviate epilepsy in cellular and rodent models. Aging (Albany NY). 2021;13:14416-14432 pubmed publisher
  15. Sánchez del Campo L, Martí Díaz R, Montenegro M, González Guerrero R, Hernández Caselles T, Martínez Barba E, et al. MITF induces escape from innate immunity in melanoma. J Exp Clin Cancer Res. 2021;40:117 pubmed publisher
  16. Wang P, Zhao L, Gong S, Xiong S, Wang J, Zou D, et al. HIF1α/HIF2α-Sox2/Klf4 promotes the malignant progression of glioblastoma via the EGFR-PI3K/AKT signalling pathway with positive feedback under hypoxia. Cell Death Dis. 2021;12:312 pubmed publisher
  17. Du J, Yu Q, Liu Y, Du S, Huang L, Xu D, et al. A novel role of kallikrein-related peptidase 8 in the pathogenesis of diabetic cardiac fibrosis. Theranostics. 2021;11:4207-4231 pubmed publisher
  18. Fan X, Zhao Z, Song J, Zhang D, Wu F, Tu J, et al. LncRNA-SNHG6 promotes the progression of hepatocellular carcinoma by targeting miR-6509-5p and HIF1A. Cancer Cell Int. 2021;21:150 pubmed publisher
  19. Choi Y, Kim Y, Oh S, Suh K, Kim Y, Lee G, et al. Senescent Tumor Cells Build a Cytokine Shield in Colorectal Cancer. Adv Sci (Weinh). 2021;8:2002497 pubmed publisher
  20. Saw E, Pearson J, Schwenke D, Munasinghe P, Tsuchimochi H, Rawal S, et al. Activation of the cardiac non-neuronal cholinergic system prevents the development of diabetes-associated cardiovascular complications. Cardiovasc Diabetol. 2021;20:50 pubmed publisher
  21. Turgu B, Zhang F, El Naggar A, Negri G, Kogler M, Tortola L, et al. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner. Oncogene. 2021;40:1988-2001 pubmed publisher
  22. Liu M, Li N, Qu C, Gao Y, Wu L, Hu L. Amylin deposition activates HIF1α and 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 (PFKFB3) signaling in failing hearts of non-human primates. Commun Biol. 2021;4:188 pubmed publisher
  23. Yagi M, Toshima T, Amamoto R, Do Y, Hirai H, Setoyama D, et al. Mitochondrial translation deficiency impairs NAD+ -mediated lysosomal acidification. EMBO J. 2021;40:e105268 pubmed publisher
  24. Isomura H, Taguchi A, Kajino T, Asai N, Nakatochi M, Kato S, et al. Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF-1α regulator. Cancer Sci. 2021;: pubmed publisher
  25. Wang Z, Shi Y, Ying C, Jiang Y, Hu J. Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling. Oncogene. 2021;: pubmed publisher
  26. Guo S, Chen Y, Yang Y, Zhang X, Ma L, Xue X, et al. TRIB2 modulates proteasome function to reduce ubiquitin stability and protect liver cancer cells against oxidative stress. Cell Death Dis. 2021;12:42 pubmed publisher
  27. Capaci V, Bascetta L, Fantuz M, Beznoussenko G, Sommaggio R, Cancila V, et al. Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome. Nat Commun. 2020;11:3945 pubmed publisher
  28. Devraj G, Guérit S, Seele J, Spitzer D, Macas J, Khel M, et al. HIF-1α is involved in blood-brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis. Acta Neuropathol. 2020;140:183-208 pubmed publisher
  29. Dmitrieva N, Walts A, Nguyen D, Grubb A, Zhang X, Wang X, et al. Impaired angiogenesis and extracellular matrix metabolism in autosomal-dominant hyper-IgE syndrome. J Clin Invest. 2020;130:4167-4181 pubmed publisher
  30. Zhang S, Kim B, Zhu X, Gui X, Wang Y, Lan Z, et al. Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways. Nat Commun. 2020;11:2027 pubmed publisher
  31. Zhou Y, Huang Y, Hu K, Zhang Z, Yang J, Wang Z. HIF1A activates the transcription of lncRNA RAET1K to modulate hypoxia-induced glycolysis in hepatocellular carcinoma cells via miR-100-5p. Cell Death Dis. 2020;11:176 pubmed publisher
  32. Li J, Tao T, Xu J, Liu Z, Zou Z, Jin M. HIF‑1α attenuates neuronal apoptosis by upregulating EPO expression following cerebral ischemia‑reperfusion injury in a rat MCAO model. Int J Mol Med. 2020;45:1027-1036 pubmed publisher
  33. Merlo S, Luaces J, Spampinato S, Toro Urrego N, Caruso G, D Amico F, et al. SIRT1 Mediates Melatonin's Effects on Microglial Activation in Hypoxia: In Vitro and In Vivo Evidence. Biomolecules. 2020;10: pubmed publisher
  34. Potilinski M, Ortiz G, Salica J, Lopez E, Fernández Acquier M, Chuluyan E, et al. Elucidating the mechanism of action of alpha-1-antitrypsin using retinal pigment epithelium cells exposed to high glucose. Potential use in diabetic retinopathy. PLoS ONE. 2020;15:e0228895 pubmed publisher
  35. Yang W, Chen Z, Ma X, Ouyang X, Fang J, Wei H. Co-overexpression of VEGF and GDNF in adipose-derived stem cells optimizes therapeutic effect in neurogenic erectile dysfunction model. Cell Prolif. 2020;53:e12756 pubmed publisher
  36. Tang H, Feng H, Wang M, Zhu Q, Liu Y, Jiang Y. In vivo longitudinal and multimodal imaging of hypoxia-inducible factor 1α and angiogenesis in breast cancer. Chin Med J (Engl). 2020;133:205-211 pubmed publisher
  37. Ghezzi C, Wong A, Chen B, Ribalet B, Damoiseaux R, Clark P. A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. Nat Commun. 2019;10:5444 pubmed publisher
  38. Wang Y, Chiang I, Ohara T, Fujii S, Cheng J, Muegge B, et al. Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells. Cell. 2019;179:1144-1159.e15 pubmed publisher
  39. Wang Y, Zhang X, Hua Z, Xie L, Jiang X, Wang R, et al. Blood Oxygen Level-Dependent Imaging and Intravoxel Incoherent Motion MRI of Early Contrast-Induced Acute Kidney Injury in a Rabbit Model. Kidney Blood Press Res. 2019;44:496-512 pubmed publisher
  40. Wohlrab C, Kuiper C, Vissers M, Phillips E, Robinson B, Dachs G. Ascorbate modulates the hypoxic pathway by increasing intracellular activity of the HIF hydroxylases in renal cell carcinoma cells. Hypoxia (Auckl). 2019;7:17-31 pubmed publisher
  41. Kurelac I, Iommarini L, Vatrinet R, Amato L, De Luise M, Leone G, et al. Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses. Nat Commun. 2019;10:903 pubmed publisher
  42. Guo H, Ci X, Ahmed M, Hua J, Soares F, Lin D, et al. ONECUT2 is a driver of neuroendocrine prostate cancer. Nat Commun. 2019;10:278 pubmed publisher
  43. Jassim A, Inman D. Evidence of Hypoxic Glial Cells in a Model of Ocular Hypertension. Invest Ophthalmol Vis Sci. 2019;60:1-15 pubmed publisher
  44. Cheng Y, Sun M, Chen L, Li Y, Lin L, Yao B, et al. Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice. Cell Rep. 2018;25:3194-3203.e4 pubmed publisher
  45. Lee M, Wang C, Jin S, Labrecque M, Beischlag T, Brockman M, et al. Expression of human inducible nitric oxide synthase in response to cytokines is regulated by hypoxia-inducible factor-1. Free Radic Biol Med. 2019;130:278-287 pubmed publisher
  46. Schwartz A, Das N, Ramakrishnan S, Jain C, Jurkovic M, Wu J, et al. Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload. J Clin Invest. 2019;129:336-348 pubmed publisher
  47. Aoki A, Nakashima A, Kusabiraki T, Ono Y, Yoshino O, Muto M, et al. Trophoblast-Specific Conditional Atg7 Knockout Mice Develop Gestational Hypertension. Am J Pathol. 2018;188:2474-2486 pubmed publisher
  48. Song K, Kim J, Lee Y, Bae H, Lee H, Woo S, et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018;128:4098-4114 pubmed publisher
  49. Kim Y, Lee M, Gu H, Kim J, Jeong S, Yeo S, et al. HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice. Dis Model Mech. 2018;11: pubmed publisher
  50. Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, de Tullio P, et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018;558:605-609 pubmed publisher
  51. Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nat Cell Biol. 2018;20:823-835 pubmed publisher
  52. Wendeln A, Degenhardt K, Kaurani L, Gertig M, Ulas T, Jain G, et al. Innate immune memory in the brain shapes neurological disease hallmarks. Nature. 2018;556:332-338 pubmed publisher
  53. Kornberg M, Bhargava P, Kim P, Putluri V, Snowman A, Putluri N, et al. Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity. Science. 2018;360:449-453 pubmed publisher
  54. Takai K, Drain A, Lawson D, Littlepage L, Karpuj M, Kessenbrock K, et al. Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers. Genes Dev. 2018;32:244-257 pubmed publisher
  55. La Porta S, Roth L, Singhal M, Mogler C, Spegg C, Schieb B, et al. Endothelial Tie1-mediated angiogenesis and vascular abnormalization promote tumor progression and metastasis. J Clin Invest. 2018;128:834-845 pubmed publisher
  56. Hira V, Wormer J, Kakar H, Breznik B, van der Swaan B, Hulsbos R, et al. Periarteriolar Glioblastoma Stem Cell Niches Express Bone Marrow Hematopoietic Stem Cell Niche Proteins. J Histochem Cytochem. 2018;66:155-173 pubmed publisher
  57. Badowska Kozakiewicz A, Sobol M, Patera J. Expression of multidrug resistance protein P-glycoprotein in correlation with markers of hypoxia (HIF-1?, EPO, EPO-R) in invasive breast cancer with metastasis to lymph nodes. Arch Med Sci. 2017;13:1303-1314 pubmed publisher
  58. Ho L, van Dijk M, Chye S, Messerschmidt D, Chng S, Ong S, et al. ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice. Science. 2017;357:707-713 pubmed publisher
  59. Yasui T, Uezono N, Nakashima H, Noguchi H, Matsuda T, Noda Andoh T, et al. Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells. Stem Cell Reports. 2017;8:1743-1756 pubmed publisher
  60. Li W, Chen C, Zhao X, Ye H, Zhao Y, Fu Z, et al. HIF-2? regulates non-canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma. J Cell Mol Med. 2017;21:2896-2908 pubmed publisher
  61. Ciria M, García N, Ontoria Oviedo I, González King H, Carrero R, de la Pompa J, et al. Mesenchymal Stem Cell Migration and Proliferation Are Mediated by Hypoxia-Inducible Factor-1α Upstream of Notch and SUMO Pathways. Stem Cells Dev. 2017;26:973-985 pubmed publisher
  62. Yuan X, Qi H, Li X, Wu F, Fang J, Bober E, et al. Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice. J Clin Invest. 2017;127:2235-2248 pubmed publisher
  63. Li S, Liu H, Tang S, Li X, Wang X. MicroRNA-150 regulates glycolysis by targeting von Hippel-Lindau in glioma cells. Am J Transl Res. 2017;9:1058-1066 pubmed
  64. Tian L, Goldstein A, Wang H, Ching Lo H, Sun Kim I, Welte T, et al. Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming. Nature. 2017;544:250-254 pubmed publisher
  65. Guo Q, He J, Shen F, Zhang W, Yang X, Zhang C, et al. TCN, an AKT inhibitor, exhibits potent antitumor activity and enhances radiosensitivity in hypoxic esophageal squamous cell carcinoma in vitro and in vivo. Oncol Lett. 2017;13:949-954 pubmed publisher
  66. An Y, Sun K, Joffin N, Zhang F, Deng Y, Donze O, et al. Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis. elife. 2017;6: pubmed publisher
  67. Liao L, Song M, Li X, Tang L, Zhang T, Zhang L, et al. E3 Ubiquitin Ligase UBR5 Drives the Growth and Metastasis of Triple-Negative Breast Cancer. Cancer Res. 2017;77:2090-2101 pubmed publisher
  68. Miles A, Burr S, Grice G, Nathan J. The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1? prolyl hydroxylation by regulating cellular iron levels. elife. 2017;6: pubmed publisher
  69. Xiao N, Yang L, Yang Y, Liu L, Li J, Liu B, et al. Ginsenoside Rg5 Inhibits Succinate-Associated Lipolysis in Adipose Tissue and Prevents Muscle Insulin Resistance. Front Pharmacol. 2017;8:43 pubmed publisher
  70. Williams P, Harder J, Foxworth N, Cochran K, Philip V, Porciatti V, et al. Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. Science. 2017;355:756-760 pubmed publisher
  71. Omatsu Kanbe M, Nozuchi N, Nishino Y, Mukaisho K, Sugihara H, Matsuura H. Identification of cardiac progenitors that survive in the ischemic human heart after ventricular myocyte death. Sci Rep. 2017;7:41318 pubmed publisher
  72. Gardner P, Liyanage S, Cristante E, Sampson R, Dick A, Ali R, et al. Hypoxia inducible factors are dispensable for myeloid cell migration into the inflamed mouse eye. Sci Rep. 2017;7:40830 pubmed publisher
  73. Bouchard G, Therriault H, Geha S, Bujold R, Saucier C, Paquette B. Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model. Br J Cancer. 2017;116:479-488 pubmed publisher
  74. Murakami A, Wang L, Kalhorn S, Schraml P, Rathmell W, Tan A, et al. Context-dependent role for chromatin remodeling component PBRM1/BAF180 in clear cell renal cell carcinoma. Oncogenesis. 2017;6:e287 pubmed publisher
  75. Jablonska B, Gierdalski M, Chew L, Hawley T, Catron M, Lichauco A, et al. Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury. Nat Commun. 2016;7:13866 pubmed publisher
  76. Yu Z, Mouillesseaux K, Kushner E, Bautch V. Tumor-Derived Factors and Reduced p53 Promote Endothelial Cell Centrosome Over-Duplication. PLoS ONE. 2016;11:e0168334 pubmed publisher
  77. Oh E, Kim J, Kim J, Kim S, Lee J, Hong S, et al. NQO1 inhibits proteasome-mediated degradation of HIF-1α. Nat Commun. 2016;7:13593 pubmed publisher
  78. Li F, Li Z, Jiang Z, Tian Y, Wang Z, Yi W, et al. Enhancement of early cardiac differentiation of dedifferentiated fat cells by dimethyloxalylglycine via notch signaling pathway. Am J Transl Res. 2016;8:4791-4801 pubmed
  79. Thompson J, Nguyen Q, Singh M, Pavesic M, Nesterenko I, Nelson L, et al. Rho-associated kinase 1 inhibition is synthetically lethal with von Hippel-Lindau deficiency in clear cell renal cell carcinoma. Oncogene. 2017;36:1080-1089 pubmed publisher
  80. Myllymäki M, Määttä J, Dimova E, Izzi V, Väisänen T, Myllyharju J, et al. Notch Downregulation and Extramedullary Erythrocytosis in Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2-Deficient Mice. Mol Cell Biol. 2017;37: pubmed publisher
  81. Chen W, Hill H, Christie A, Kim M, Holloman E, Pavía Jiménez A, et al. Targeting renal cell carcinoma with a HIF-2 antagonist. Nature. 2016;539:112-117 pubmed publisher
  82. Arvola O, Haapanen H, Herajärvi J, Anttila T, Puistola U, Karihtala P, et al. Remote Ischemic Preconditioning Reduces Cerebral Oxidative Stress Following Hypothermic Circulatory Arrest in a Porcine Model. Semin Thorac Cardiovasc Surg. 2016;28:92-102 pubmed publisher
  83. Cao L, Zhang L, Zhao X, Zhang Y. A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells. PLoS ONE. 2016;11:e0161025 pubmed publisher
  84. Guimarães T, Farias L, Santos E, De Carvalho Fraga C, Orsini L, de Freitas Teles L, et al. Metformin increases PDH and suppresses HIF-1? under hypoxic conditions and induces cell death in oral squamous cell carcinoma. Oncotarget. 2016;7:55057-55068 pubmed publisher
  85. Takasaki C, Kobayashi M, Ishibashi H, Akashi T, Okubo K. Expression of hypoxia-inducible factor-1? affects tumor proliferation and antiapoptosis in surgically resected lung cancer. Mol Clin Oncol. 2016;5:295-300 pubmed
  86. Schokrpur S, Hu J, Moughon D, Liu P, Lin L, Hermann K, et al. CRISPR-Mediated VHL Knockout Generates an Improved Model for Metastatic Renal Cell Carcinoma. Sci Rep. 2016;6:29032 pubmed publisher
  87. Colombo J, Maciel J, Ferreira L, da Silva R, Zuccari D. Effects of melatonin on HIF-1? and VEGF expression and on the invasive properties of hepatocarcinoma cells. Oncol Lett. 2016;12:231-237 pubmed
  88. Zhao W, Li A, Feng X, Hou T, Liu K, Liu B, et al. Metformin and resveratrol ameliorate muscle insulin resistance through preventing lipolysis and inflammation in hypoxic adipose tissue. Cell Signal. 2016;28:1401-11 pubmed publisher
  89. Higashimura Y, Kitakaze T, Harada N, Inui H, Nakano Y, Yamaji R. pVHL-mediated degradation of HIF-2? regulates estrogen receptor ? expression in normoxic breast cancer cells. FEBS Lett. 2016;590:2690-9 pubmed publisher
  90. Maugeri G, D Amico A, Reitano R, Magro G, Cavallaro S, Salomone S, et al. PACAP and VIP Inhibit the Invasiveness of Glioblastoma Cells Exposed to Hypoxia through the Regulation of HIFs and EGFR Expression. Front Pharmacol. 2016;7:139 pubmed publisher
  91. Hoefflin R, Lahrmann B, Warsow G, Hübschmann D, Spath C, Walter B, et al. Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity. Nat Commun. 2016;7:ncomms11845 pubmed publisher
  92. Lo Dico A, Costa V, Martelli C, Diceglie C, Rajata F, Rizzo A, et al. MiR675-5p Acts on HIF-1? to Sustain Hypoxic Responses: A New Therapeutic Strategy for Glioma. Theranostics. 2016;6:1105-18 pubmed publisher
  93. Salvi V, Vermi W, Gianello V, Lonardi S, Gagliostro V, Naldini A, et al. Dendritic cell-derived VEGF-A plays a role in inflammatory angiogenesis of human secondary lymphoid organs and is driven by the coordinated activation of multiple transcription factors. Oncotarget. 2016;7:39256-39269 pubmed publisher
  94. Spitzbarth I, Lempp C, Kegler K, Ulrich R, Kalkuhl A, Deschl U, et al. Immunohistochemical and transcriptome analyses indicate complex breakdown of axonal transport mechanisms in canine distemper leukoencephalitis. Brain Behav. 2016;6:e00472 pubmed publisher
  95. Piton N, Wason J, Colasse É, Cornic M, Lemoine F, Le Pessot F, et al. Endoplasmic reticulum stress, unfolded protein response and development of colon adenocarcinoma. Virchows Arch. 2016;469:145-54 pubmed publisher
  96. Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, et al. HIF-1?-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity. Nat Commun. 2016;7:11635 pubmed publisher
  97. Cherepanova O, Gomez D, Shankman L, Swiatlowska P, Williams J, Sarmento O, et al. Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective. Nat Med. 2016;22:657-65 pubmed publisher
  98. Guinot A, Lehmann H, Wild P, Frew I. Combined deletion of Vhl, Trp53 and Kif3a causes cystic and neoplastic renal lesions. J Pathol. 2016;239:365-73 pubmed publisher
  99. Okawa H, Kayashima H, Sasaki J, Miura J, Kamano Y, Kosaka Y, et al. Scaffold-Free Fabrication of Osteoinductive Cellular Constructs Using Mouse Gingiva-Derived Induced Pluripotent Stem Cells. Stem Cells Int. 2016;2016:6240794 pubmed publisher
  100. Kobayashi H, Liu Q, Binns T, Urrutia A, Davidoff O, Kapitsinou P, et al. Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin. J Clin Invest. 2016;126:1926-38 pubmed publisher
  101. Xu X, Tan X, Hulshoff M, Wilhelmi T, Zeisberg M, Zeisberg E. Hypoxia-induced endothelial-mesenchymal transition is associated with RASAL1 promoter hypermethylation in human coronary endothelial cells. FEBS Lett. 2016;590:1222-33 pubmed publisher
  102. Park S, Kim J, Kim N, Yang K, Shim J, Heo K. Estradiol, TGF-?1 and hypoxia promote breast cancer stemness and EMT-mediated breast cancer migration. Oncol Lett. 2016;11:1895-1902 pubmed
  103. Ananthula S, Sinha A, El Gassim M, Batth S, Marshall G, Gardner L, et al. Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers. Oncotarget. 2016;7:20869-89 pubmed publisher
  104. Shukla P, Chaudhry K, Mir H, Gangwar R, Yadav N, Manda B, et al. Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation. BMC Cancer. 2016;16:189 pubmed publisher
  105. Djamali A, Wilson N, Sadowski E, Zha W, Niles D, Hafez O, et al. Nox2 and Cyclosporine-Induced Renal Hypoxia. Transplantation. 2016;100:1198-210 pubmed publisher
  106. Ruf M, Moch H, Schraml P. PD-L1 expression is regulated by hypoxia inducible factor in clear cell renal cell carcinoma. Int J Cancer. 2016;139:396-403 pubmed publisher
  107. Karuppagounder S, Alim I, Khim S, Bourassa M, Sleiman S, John R, et al. Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Sci Transl Med. 2016;8:328ra29 pubmed publisher
  108. Zhou F, Dai A, Jiang Y, Tan X, Zhang X. SENP‑1 enhances hypoxia‑induced proliferation of rat pulmonary artery smooth muscle cells by regulating hypoxia‑inducible factor‑1α. Mol Med Rep. 2016;13:3482-90 pubmed publisher
  109. Edalat L, Stegen B, Klumpp L, Haehl E, Schilbach K, Lukowski R, et al. BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells. Oncotarget. 2016;7:14259-78 pubmed publisher
  110. Chowdhury H, Velebit J, Radić N, Frančič V, Kreft M, Zorec R. Hypoxia Alters the Expression of Dipeptidyl Peptidase 4 and Induces Developmental Remodeling of Human Preadipocytes. J Diabetes Res. 2016;2016:7481470 pubmed publisher
  111. Adighibe O, Leek R, Fernandez Mercado M, Hu J, Snell C, Gatter K, et al. Why some tumours trigger neovascularisation and others don't: the story thus far. Chin J Cancer. 2016;35:18 pubmed publisher
  112. Mori H, Yao Y, Learman B, Kurozumi K, Ishida J, Ramakrishnan S, et al. Induction of WNT11 by hypoxia and hypoxia-inducible factor-1α regulates cell proliferation, migration and invasion. Sci Rep. 2016;6:21520 pubmed publisher
  113. Wang P, Li L, Zhang Z, Kan Q, Chen S, Gao F. Time-dependent homeostasis between glucose uptake and consumption in astrocytes exposed to CoClâ‚‚ treatment. Mol Med Rep. 2016;13:2909-17 pubmed publisher
  114. Regan Anderson T, Ma S, Raj G, Cidlowski J, Helle T, Knutson T, et al. Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer. Cancer Res. 2016;76:1653-63 pubmed publisher
  115. Nalwoga H, Ahmed L, Arnes J, Wabinga H, Akslen L. Strong Expression of Hypoxia-Inducible Factor-1α (HIF-1α) Is Associated with Axl Expression and Features of Aggressive Tumors in African Breast Cancer. PLoS ONE. 2016;11:e0146823 pubmed publisher
  116. Kim Y, Nam H, Lee J, Park D, Kim C, Yu Y, et al. Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis. Nat Commun. 2016;7:10347 pubmed publisher
  117. Lin A, Li C, Xing Z, Hu Q, Liang K, Han L, et al. The LINK-A lncRNA activates normoxic HIF1? signalling in triple-negative breast cancer. Nat Cell Biol. 2016;18:213-24 pubmed publisher
  118. Chen K, Zeng J, Xiao H, Huang C, Hu J, Yao W, et al. Regulation of glucose metabolism by p62/SQSTM1 through HIF1α. J Cell Sci. 2016;129:817-30 pubmed publisher
  119. Maugeri G, D Amico A, Reitano R, Saccone S, Federico C, Cavallaro S, et al. Parkin modulates expression of HIF-1α and HIF-3α during hypoxia in gliobastoma-derived cell lines in vitro. Cell Tissue Res. 2016;364:465-474 pubmed publisher
  120. Lee S, Frattini V, Bansal M, Castano A, Sherman D, Hutchinson K, et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016;529:172-7 pubmed publisher
  121. Sharpe M, Baskin D. Monoamine oxidase B levels are highly expressed in human gliomas and are correlated with the expression of HiF-1α and with transcription factors Sp1 and Sp3. Oncotarget. 2016;7:3379-93 pubmed publisher
  122. Yamano S, Gi M, Tago Y, Doi K, Okada S, Hirayama Y, et al. Role of deltaNp63(pos)CD44v(pos) cells in the development of N-nitroso-tris-chloroethylurea-induced peripheral-type mouse lung squamous cell carcinomas. Cancer Sci. 2016;107:123-32 pubmed publisher
  123. Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed publisher
  124. de Jong O, van Balkom B, Gremmels H, Verhaar M. Exosomes from hypoxic endothelial cells have increased collagen crosslinking activity through up-regulation of lysyl oxidase-like 2. J Cell Mol Med. 2016;20:342-50 pubmed publisher
  125. Aquino Gálvez A, González Ávila G, Delgado Tello J, Castillejos López M, Mendoza Milla C, Zúñiga J, et al. Effects of 2-methoxyestradiol on apoptosis and HIF-1α and HIF-2α expression in lung cancer cells under normoxia and hypoxia. Oncol Rep. 2016;35:577-83 pubmed publisher
  126. Shen G, Ning N, Zhao X, Liu X, Wang G, Wang T, et al. Adipose differentiation-related protein is not involved in hypoxia inducible factor-1-induced lipid accumulation under hypoxia. Mol Med Rep. 2015;12:8055-61 pubmed publisher
  127. Chen P, Weng J, Hsu P, Shew J, Huang Y, Lee W. NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress. Nucleic Acids Res. 2015;43:9393-404 pubmed publisher
  128. Konzack A, Jakupovic M, Kubaichuk K, Görlach A, Dombrowski F, Miinalainen I, et al. Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis. Antioxid Redox Signal. 2015;23:1059-75 pubmed publisher
  129. Saini Y, Proper S, Dornbos P, Greenwood K, Kopec A, Lynn S, et al. Loss of Hif-2α Rescues the Hif-1α Deletion Phenotype of Neonatal Respiratory Distress In Mice. PLoS ONE. 2015;10:e0139270 pubmed publisher
  130. Singh S, Chand H, Gundavarapu S, Saeed A, Langley R, Tesfaigzi Y, et al. HIF-1α Plays a Critical Role in the Gestational Sidestream Smoke-Induced Bronchopulmonary Dysplasia in Mice. PLoS ONE. 2015;10:e0137757 pubmed publisher
  131. Rodríguez C, Reidel S, Bal de Kier Joffé E, Jasnis M, Fiszman G. Autophagy Protects from Trastuzumab-Induced Cytotoxicity in HER2 Overexpressing Breast Tumor Spheroids. PLoS ONE. 2015;10:e0137920 pubmed publisher
  132. Ochi F, Shiozaki A, Ichikawa D, Fujiwara H, Nakashima S, Takemoto K, et al. Carbonic Anhydrase XII as an Independent Prognostic Factor in Advanced Esophageal Squamous Cell Carcinoma. J Cancer. 2015;6:922-9 pubmed publisher
  133. Huang J, Liu L, Feng M, An S, Zhou M, Li Z, et al. Effect of CoClâ‚‚ on fracture repair in a rat model of bone fracture. Mol Med Rep. 2015;12:5951-6 pubmed publisher
  134. Wang I, Sun K, Tsai T, Chen C, Chang S, Yu T, et al. MiR-20a-5p mediates hypoxia-induced autophagy by targeting ATG16L1 in ischemic kidney injury. Life Sci. 2015;136:133-41 pubmed publisher
  135. Kontro H, Cannino G, Rustin P, Dufour E, Kainulainen H. DAPIT Over-Expression Modulates Glucose Metabolism and Cell Behaviour in HEK293T Cells. PLoS ONE. 2015;10:e0131990 pubmed publisher
  136. Chan M, Atasoylu O, Hodson E, Tumber A, Leung I, Chowdhury R, et al. Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain. PLoS ONE. 2015;10:e0132004 pubmed publisher
  137. Yang X, Zheng K, Lin K, Zheng G, Zou H, Wang J, et al. Energy Metabolism Disorder as a Contributing Factor of Rheumatoid Arthritis: A Comparative Proteomic and Metabolomic Study. PLoS ONE. 2015;10:e0132695 pubmed publisher
  138. Yang L, Li Y, Bhattacharya A, Zhang Y. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015;2:396-405 pubmed
  139. Li X, Yang X, Biskup E, Zhou J, Li H, Wu Y, et al. Co-expression of CXCL8 and HIF-1α is associated with metastasis and poor prognosis in hepatocellular carcinoma. Oncotarget. 2015;6:22880-9 pubmed
  140. Xie L, Pi X, Townley Tilson W, Li N, Wehrens X, Entman M, et al. PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban. J Clin Invest. 2015;125:2759-71 pubmed publisher
  141. Park I, Chung P, Ahn J. Enhancement of Ischemic Wound Healing by Spheroid Grafting of Human Adipose-Derived Stem Cells Treated with Low-Level Light Irradiation. PLoS ONE. 2015;10:e0122776 pubmed publisher
  142. Yorulmaz H, Ozkok E, Erguven M, Ates G, Aydın I, Tamer S. Effect of simvastatin on mitochondrial enzyme activities, ghrelin, hypoxia-inducible factor 1α in hepatic tissue during early phase of sepsis. Int J Clin Exp Med. 2015;8:3640-50 pubmed
  143. Espana Agusti J, Tuveson D, Adams D, Matakidou A. A minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules. Sci Rep. 2015;5:11061 pubmed publisher
  144. Sun L, Xu C, Chen G, Yu M, Yang S, Qiu Y, et al. A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway. Int J Biol Sci. 2015;11:664-71 pubmed publisher
  145. Zhang Y, Fan N, Yang J. Expression and clinical significance of hypoxia-inducible factor 1?, Snail and E-cadherin in human ovarian cancer cell lines. Mol Med Rep. 2015;12:3393-3399 pubmed publisher
  146. Kumar P, Gullberg U, Olsson I, Ajore R. Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1. PLoS ONE. 2015;10:e0123725 pubmed publisher
  147. Ferreira J, Soares A, Ramalho J, Pereira P, Girao H. K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy. Sci Rep. 2015;5:10210 pubmed publisher
  148. Park H, Lee D, Yim M, Choi Y, Park S, Seo S, et al. 3,3'-Diindolylmethane inhibits VEGF expression through the HIF-1α and NF-κB pathways in human retinal pigment epithelial cells under chemical hypoxic conditions. Int J Mol Med. 2015;36:301-8 pubmed publisher
  149. Bánfi G, Teleki I, Nyirády P, Keszthelyi A, Romics I, Fintha A, et al. Changes of protein expression in prostate cancer having lost its androgen sensitivity. Int Urol Nephrol. 2015;47:1149-54 pubmed publisher
  150. Sadowski S, Boufraqech M, Zhang L, Mehta A, Kapur P, Zhang Y, et al. Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis. Oncotarget. 2015;6:18038-49 pubmed
  151. Guven M, Sehitoglu M, Yüksel Y, Tokmak M, Aras A, Akman T, et al. The Neuroprotective Effect of Coumaric Acid on Spinal Cord Ischemia/Reperfusion Injury in Rats. Inflammation. 2015;38:1986-95 pubmed publisher
  152. Basu S, Majumder S, Bhowal A, Ghosh A, Naskar S, Nandy S, et al. A study of molecular signals deregulating mismatch repair genes in prostate cancer compared to benign prostatic hyperplasia. PLoS ONE. 2015;10:e0125560 pubmed publisher
  153. Kim B, Lee J, Choi J, Park D, Song H, Park T, et al. Imidazole-based alkaloid derivative LCB54-0009 suppresses ocular angiogenesis and lymphangiogenesis in models of experimental retinopathy and corneal neovascularization. Br J Pharmacol. 2015;172:3875-89 pubmed publisher
  154. Qiao S, Dennis M, Song X, Vadysirisack D, Salunke D, Nash Z, et al. A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity. Nat Commun. 2015;6:7014 pubmed publisher
  155. Liu X, Chen Z, Xu C, Leng X, Cao H, Ouyang G, et al. Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation. Nucleic Acids Res. 2015;43:5081-98 pubmed publisher
  156. Sun Y, George J, Rocha S. Dose-dependent effects of allopurinol on human foreskin fibroblast cells and human umbilical vein endothelial cells under hypoxia. PLoS ONE. 2015;10:e0123649 pubmed publisher
  157. Verduzco D, Lloyd M, Xu L, Ibrahim Hashim A, Balagurunathan Y, Gatenby R, et al. Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance. PLoS ONE. 2015;10:e0120958 pubmed publisher
  158. Chan N, He S, Spee C, Ishikawa K, Hinton D. Attenuation of choroidal neovascularization by histone deacetylase inhibitor. PLoS ONE. 2015;10:e0120587 pubmed publisher
  159. Koh H, Chang C, Jeon S, Yoon H, Ahn Y, Kim H, et al. The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia. Nat Commun. 2015;6:6340 pubmed publisher
  160. Albers J, Danzer C, Rechsteiner M, Lehmann H, Brandt L, Hejhal T, et al. A versatile modular vector system for rapid combinatorial mammalian genetics. J Clin Invest. 2015;125:1603-19 pubmed publisher
  161. Yang L, Liu L, Xu Z, Liao W, Feng D, Dong X, et al. EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma. Oncotarget. 2015;6:5804-17 pubmed
  162. Yu C, Yang S, Fang X, Jiang J, Sun C, Huang T. Hypoxia disrupts the expression levels of circadian rhythm genes in hepatocellular carcinoma. Mol Med Rep. 2015;11:4002-8 pubmed publisher
  163. Shankar G, Taylor Weiner A, Lelic N, Jones R, Kim J, FRANCIS J, et al. Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathol Commun. 2014;2:167 pubmed publisher
  164. Mudie S, Bandarra D, Batie M, Biddlestone J, Moniz S, Ortmann B, et al. PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia. Cell Cycle. 2014;13:3878-91 pubmed publisher
  165. Cannito S, Turato C, Paternostro C, Biasiolo A, Colombatto S, Cambieri I, et al. Hypoxia up-regulates SERPINB3 through HIF-2α in human liver cancer cells. Oncotarget. 2015;6:2206-21 pubmed
  166. Hung Y, Chang S, Huang C, Yin J, Hwang C, Yang L, et al. Inhibitor of Differentiation-1 and Hypoxia-Inducible Factor-1 Mediate Sonic Hedgehog Induction by Amyloid Beta-Peptide in Rat Cortical Neurons. Mol Neurobiol. 2016;53:793-809 pubmed publisher
  167. Rutz S, Kayagaki N, Phung Q, Eidenschenk C, Noubade R, Wang X, et al. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature. 2015;518:417-21 pubmed publisher
  168. Fine J, Renner D, Forsberg A, Cameron R, Galick B, Le C, et al. Intranasal deferoxamine engages multiple pathways to decrease memory loss in the APP/PS1 model of amyloid accumulation. Neurosci Lett. 2015;584:362-7 pubmed publisher
  169. Ma B, Chen Y, Chen L, Cheng H, Mu C, Li J, et al. Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase. Nat Cell Biol. 2015;17:95-103 pubmed publisher
  170. Mazzatenta A, Marconi G, Zara S, Cataldi A, Porzionato A, Di Giulio C. In the carotid body, galanin is a signal for neurogenesis in young, and for neurodegeneration in the old and in drug-addicted subjects. Front Physiol. 2014;5:427 pubmed publisher
  171. Basham K, Leonard C, Kieffer C, Shelton D, McDowell M, Bhonde V, et al. Dioxin exposure blocks lactation through a direct effect on mammary epithelial cells mediated by the aryl hydrocarbon receptor repressor. Toxicol Sci. 2015;143:36-45 pubmed publisher
  172. Lee H, Kim K, Lim H, Choi M, Kim H, Ahn H, et al. Priming Wharton's jelly-derived mesenchymal stromal/stem cells with ROCK inhibitor improves recovery in an intracerebral hemorrhage model. J Cell Biochem. 2015;116:310-9 pubmed publisher
  173. Miao Z, Wang Z, Zhao T, Xu Y, Gao J, Miao F, et al. Peritoneal milky spots serve as a hypoxic niche and favor gastric cancer stem/progenitor cell peritoneal dissemination through hypoxia-inducible factor 1α. Stem Cells. 2014;32:3062-74 pubmed publisher
  174. Huang T, Huang W, Zhang Z, Yu L, Xie C, Zhu D, et al. Hypoxia-inducible factor-1? upregulation in microglia following hypoxia protects against ischemia-induced cerebral infarction. Neuroreport. 2014;25:1122-8 pubmed publisher
  175. Hempel C, Hoyer N, Kildemoes A, Jendresen C, Kurtzhals J. Systemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment. Front Immunol. 2014;5:291 pubmed publisher
  176. Zheng X, Zhai B, Koivunen P, Shin S, Lu G, Liu J, et al. Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase. Genes Dev. 2014;28:1429-44 pubmed publisher
  177. Schreurs L, Smit J, Pavlov K, Pultrum B, Pruim J, Groen H, et al. Prognostic impact of clinicopathological features and expression of biomarkers related to (18)F-FDG uptake in esophageal cancer. Ann Surg Oncol. 2014;21:3751-7 pubmed publisher
  178. Ramamoorthy P, Shi H. Ischemia induces different levels of hypoxia inducible factor-1? protein expression in interneurons and pyramidal neurons. Acta Neuropathol Commun. 2014;2:51 pubmed publisher
  179. Waza A, Andrabi K, Hussain M. Protein kinase C (PKC) mediated interaction between conexin43 (Cx43) and K(+)(ATP) channel subunit (Kir6.1) in cardiomyocyte mitochondria: Implications in cytoprotection against hypoxia induced cell apoptosis. Cell Signal. 2014;26:1909-17 pubmed publisher
  180. Wu W, Tian R, Hao S, Xu F, Mao X, Liu B. A pre-injury high ethanol intake in rats promotes brain edema following traumatic brain injury. Br J Neurosurg. 2014;28:739-45 pubmed publisher
  181. Schaffner C, Mwinyi J, Gai Z, Thasler W, Eloranta J, Kullak Ublick G. The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes. Liver Int. 2015;35:1152-61 pubmed publisher
  182. Aksu V, Yuksel V, Chousein S, Tastekin E, Iscan S, Sagiroglu G, et al. The effects of sildenafil and n-acetylcysteine on ischemia and reperfusion injury in gastrocnemius muscle and femoral artery endothelium. Vascular. 2015;23:21-30 pubmed publisher
  183. Sun X, Fang B, Zhao X, Zhang G, Ma H. Preconditioning of mesenchymal stem cells by sevoflurane to improve their therapeutic potential. PLoS ONE. 2014;9:e90667 pubmed publisher
  184. Ekman M, Uvelius B, Albinsson S, Swärd K. HIF-mediated metabolic switching in bladder outlet obstruction mitigates the relaxing effect of mitochondrial inhibition. Lab Invest. 2014;94:557-68 pubmed publisher
  185. Kulzer J, Stitzel M, Morken M, Huyghe J, Fuchsberger C, Kuusisto J, et al. A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell. Am J Hum Genet. 2014;94:186-97 pubmed publisher
  186. Chen T, Shih Y, Tseng J, Lai M, Wu C, Li Y, et al. Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation. Nucleic Acids Res. 2014;42:2932-44 pubmed publisher
  187. Ding H, Gao Y, Wang Y, Hu C, Sun Y, Zhang C. Dimethyloxaloylglycine increases the bone healing capacity of adipose-derived stem cells by promoting osteogenic differentiation and angiogenic potential. Stem Cells Dev. 2014;23:990-1000 pubmed publisher
  188. Maschio L, Madallozo B, Capellasso B, Jardim B, Moschetta M, Jampietro J, et al. Immunohistochemical investigation of the angiogenic proteins VEGF, HIF-1? and CD34 in invasive ductal carcinoma of the breast. Acta Histochem. 2014;116:148-57 pubmed publisher
  189. Xie L, Collins J. Transcription factors Sp1 and Hif2α mediate induction of the copper-transporting ATPase (Atp7a) gene in intestinal epithelial cells during hypoxia. J Biol Chem. 2013;288:23943-52 pubmed publisher
  190. Cao W, Kawai N, Miyake K, Zhang X, Fei Z, Tamiya T. Relationship of 14-3-3zeta (?), HIF-1?, and VEGF expression in human brain gliomas. Brain Tumor Pathol. 2014;31:1-10 pubmed publisher
  191. Salem A, Howell A, Sartini M, Sotgia F, Lisanti M. Downregulation of stromal BRCA1 drives breast cancer tumor growth via upregulation of HIF-1?, autophagy and ketone body production. Cell Cycle. 2012;11:4167-73 pubmed publisher
  192. Hsieh Y, Chou L, Chang P, Yang C, Kao M, Hong C. Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury: possible involvements in hypoxia-inducible factor 1? (HIF-1?). J Comp Neurol. 2012;520:2903-16 pubmed publisher
  193. Groenman F, Rutter M, Caniggia I, Tibboel D, Post M. Hypoxia-inducible factors in the first trimester human lung. J Histochem Cytochem. 2007;55:355-63 pubmed