This is a Validated Antibody Database (VAD) review about mouse Hdac3, based on 39 published articles (read how Labome selects the articles), using Hdac3 antibody in all methods. It is aimed to help Labome visitors find the most suited Hdac3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Hdac3 synonym: AW537363

Knockout validation
Cell Signaling Technology
mouse monoclonal (7G6C5)
  • immunohistochemistry knockout validation; mouse; fig S1a
Cell Signaling Technology Hdac3 antibody (Cell Signaling, 3949) was used in immunohistochemistry knockout validation on mouse samples (fig S1a). Nat Neurosci (2016) ncbi
Abcam
domestic rabbit monoclonal (Y415)
  • western blot; human; 1:2000; loading ...; fig 6e
Abcam Hdac3 antibody (Abcam, ab32369) was used in western blot on human samples at 1:2000 (fig 6e). Bioengineered (2022) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:2000; loading ...
Abcam Hdac3 antibody (Abcam, ab7030) was used in western blot on rat samples at 1:2000. Signal Transduct Target Ther (2021) ncbi
domestic rabbit polyclonal
  • ChIP-Seq; mouse; ; loading ...; fig s11a
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s3c
  • chromatin immunoprecipitation; mouse; ; loading ...; fig 2i
  • immunoprecipitation; mouse; ; loading ...; fig 2e
  • western blot; mouse; loading ...; fig 2c
Abcam Hdac3 antibody (Abcam, ab7030) was used in ChIP-Seq on mouse samples at (fig s11a), in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s3c), in chromatin immunoprecipitation on mouse samples at (fig 2i), in immunoprecipitation on mouse samples at (fig 2e) and in western blot on mouse samples (fig 2c). Science (2019) ncbi
domestic rabbit monoclonal (Y415)
  • immunocytochemistry; human; loading ...; fig 3d
  • western blot; human; loading ...; fig 3c
Abcam Hdac3 antibody (Abcam, ab32369) was used in immunocytochemistry on human samples (fig 3d) and in western blot on human samples (fig 3c). Cell (2019) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig s4b
  • western blot; human; 1:100; loading ...; fig 3a
Abcam Hdac3 antibody (Abcam, ab7030) was used in chromatin immunoprecipitation on human samples (fig s4b) and in western blot on human samples at 1:100 (fig 3a). Nat Commun (2018) ncbi
domestic rabbit monoclonal (Y415)
  • western blot; zebrafish ; 1:1000; loading ...; fig 7p
In order to investigate the genetic regulators of endothelial precursors in great vessel vasculogenesis, Abcam Hdac3 antibody (Abcam, ab32369) was used in western blot on zebrafish samples at 1:1000 (fig 7p). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; mouse; 1:50; loading ...; fig 4D
  • immunoprecipitation; mouse; 1:50; loading ...; fig 4C
  • western blot; mouse; 1:1000; loading ...; fig 4C
Abcam Hdac3 antibody (Abcam, ab7030) was used in chromatin immunoprecipitation on mouse samples at 1:50 (fig 4D), in immunoprecipitation on mouse samples at 1:50 (fig 4C) and in western blot on mouse samples at 1:1000 (fig 4C). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig 3i
In order to discuss how c-jun regulates astrocyte elevated gene-1 in gliomas, Abcam Hdac3 antibody (Abcam, ab7030) was used in chromatin immunoprecipitation on human samples (fig 3i). Mol Cell Biol (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:500; loading ...; fig s1c
Abcam Hdac3 antibody (Abcam, ab7030) was used in immunocytochemistry on human samples at 1:500 (fig s1c). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (Y415)
  • chromatin immunoprecipitation; human; fig 6
  • western blot; human; fig s1
Abcam Hdac3 antibody (Abcam, ab32369) was used in chromatin immunoprecipitation on human samples (fig 6) and in western blot on human samples (fig s1). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • flow cytometry; mouse; loading ...; fig 5d
Abcam Hdac3 antibody (Abcam, ab7030) was used in flow cytometry on mouse samples (fig 5d). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; mouse; fig S5f
Abcam Hdac3 antibody (Abcam, ab7030) was used in chromatin immunoprecipitation on mouse samples (fig S5f). Nat Neurosci (2016) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; mouse; fig 1
Abcam Hdac3 antibody (Abcam, AB7030) was used in chromatin immunoprecipitation on mouse samples (fig 1). elife (2016) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; fig 2
  • western blot; human; 1:2000; fig 7
In order to study how nuclear corepressor 1 contributes to cancer, Abcam Hdac3 antibody (Abcam, 7030) was used in chromatin immunoprecipitation on human samples (fig 2) and in western blot on human samples at 1:2000 (fig 7). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (Y415)
  • western blot; human; 1:1000; fig 6a
Abcam Hdac3 antibody (Abcam, ab32369) was used in western blot on human samples at 1:1000 (fig 6a). Oncotarget (2016) ncbi
domestic rabbit monoclonal (Y415)
  • immunohistochemistry; human; 1:200; fig 2
Abcam Hdac3 antibody (Abcam, ab32369) was used in immunohistochemistry on human samples at 1:200 (fig 2). Cancer Sci (2015) ncbi
domestic rabbit polyclonal
Abcam Hdac3 antibody (Abcam, ab7030) was used . PLoS ONE (2014) ncbi
domestic rabbit monoclonal (Y415)
  • western blot; mouse; 1:2000; fig 3
Abcam Hdac3 antibody (Abcam, Ab32369) was used in western blot on mouse samples at 1:2000 (fig 3). Proc Natl Acad Sci U S A (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (3G6)
  • western blot; rat; 1:5000; loading ...; fig 1c
Santa Cruz Biotechnology Hdac3 antibody (Santa Cruz, sc81600) was used in western blot on rat samples at 1:5000 (fig 1c). J Neuroinflammation (2021) ncbi
mouse monoclonal (A-3)
  • western blot; human; fig 4a
Santa Cruz Biotechnology Hdac3 antibody (Santa Cruz, sc376957) was used in western blot on human samples (fig 4a). Cell Death Dis (2021) ncbi
mouse monoclonal (A-3)
  • western blot; mouse; 1:500; loading ...; fig 4n
Santa Cruz Biotechnology Hdac3 antibody (Santa Cruz, sc-376957) was used in western blot on mouse samples at 1:500 (fig 4n). PLoS Biol (2020) ncbi
mouse monoclonal (A-3)
  • western blot; human; fig 7c
Santa Cruz Biotechnology Hdac3 antibody (Santa Cruz Biotechnology, sc-376957) was used in western blot on human samples (fig 7c). iScience (2019) ncbi
mouse monoclonal (A-3)
Santa Cruz Biotechnology Hdac3 antibody (Santa Cruz, sc-376957) was used . Cell (2019) ncbi
mouse monoclonal (B-12)
  • western blot; human; fig 3
In order to analyze tamoxifen-resistance in ERalpha-positive breast cancer by degradation of NCoR due to COPS5 amplification and overexpression, Santa Cruz Biotechnology Hdac3 antibody (Santa Cruz, sc-17795) was used in western blot on human samples (fig 3). Nat Commun (2016) ncbi
mouse monoclonal (B-12)
  • western blot; mouse; fig 5
Santa Cruz Biotechnology Hdac3 antibody (Santa Cruz, sc-17795) was used in western blot on mouse samples (fig 5). elife (2016) ncbi
mouse monoclonal (40)
  • western blot; rat
Santa Cruz Biotechnology Hdac3 antibody (Santa Cruz Biotechnology, sc-136290) was used in western blot on rat samples . Cell Signal (2014) ncbi
mouse monoclonal (B-12)
  • western blot; human
Santa Cruz Biotechnology Hdac3 antibody (Santa Cruz, sc-17795) was used in western blot on human samples . Cancer Res (2013) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D2O1K)
  • chromatin immunoprecipitation; human; 1:50; loading ...; fig 6f
Cell Signaling Technology Hdac3 antibody (Cell Signaling, 85057) was used in chromatin immunoprecipitation on human samples at 1:50 (fig 6f). Redox Biol (2022) ncbi
mouse monoclonal (7G6C5)
  • western blot; human; 1:1000; fig s1b
Cell Signaling Technology Hdac3 antibody (Cell Signaling, 3949) was used in western blot on human samples at 1:1000 (fig s1b). JCI Insight (2021) ncbi
mouse monoclonal (7G6C5)
  • western blot; human; loading ...; fig 3s2a
Cell Signaling Technology Hdac3 antibody (Cell Signaling, 3949) was used in western blot on human samples (fig 3s2a). elife (2019) ncbi
domestic rabbit monoclonal (D2O1K)
  • chromatin immunoprecipitation; mouse; loading ...; fig 5h
Cell Signaling Technology Hdac3 antibody (Cell Signaling, 85057) was used in chromatin immunoprecipitation on mouse samples (fig 5h). elife (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s1
Cell Signaling Technology Hdac3 antibody (Cell Signaling Technology, 2632) was used in western blot on human samples (fig s1). Cell Rep (2018) ncbi
mouse monoclonal (7G6C5)
  • western blot; human; 1:1000; loading ...; fig s4a
Cell Signaling Technology Hdac3 antibody (Cell Signaling, 3949) was used in western blot on human samples at 1:1000 (fig s4a). Nature (2018) ncbi
mouse monoclonal (7G6C5)
  • western blot; human; loading ...; fig 6c
Cell Signaling Technology Hdac3 antibody (Cell signaling, 3949) was used in western blot on human samples (fig 6c). Ann Neurol (2016) ncbi
mouse monoclonal (7G6C5)
  • immunohistochemistry knockout validation; mouse; fig S1a
Cell Signaling Technology Hdac3 antibody (Cell Signaling, 3949) was used in immunohistochemistry knockout validation on mouse samples (fig S1a). Nat Neurosci (2016) ncbi
mouse monoclonal (7G6C5)
  • western blot; rat; fig 5c
Cell Signaling Technology Hdac3 antibody (Cell signaling, 3949) was used in western blot on rat samples (fig 5c). Cell Signal (2016) ncbi
mouse monoclonal (7G6C5)
  • western blot; human; fig 7
Cell Signaling Technology Hdac3 antibody (Cell signaling, 3949) was used in western blot on human samples (fig 7). Oncogenesis (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:100; fig 5
  • western blot; human; 1:500; fig 1b
Cell Signaling Technology Hdac3 antibody (Cell Signaling Technology, 2632) was used in immunocytochemistry on human samples at 1:100 (fig 5) and in western blot on human samples at 1:500 (fig 1b). PLoS Pathog (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1b
In order to study the effects of a HDAC 3-selective inhibitor, RGFP966, on NF-kB and histones, Cell Signaling Technology Hdac3 antibody (Cell Signaling, 2632) was used in western blot on mouse samples at 1:1000 (fig 1b). Biochem Pharmacol (2016) ncbi
mouse monoclonal (7G6C5)
  • immunocytochemistry; mouse; 1:100; loading ...; fig 7a
  • western blot; mouse; 1:1000; loading ...; fig 1b
In order to study the effects of a HDAC 3-selective inhibitor, RGFP966, on NF-kB and histones, Cell Signaling Technology Hdac3 antibody (Cell Signaling, 3949) was used in immunocytochemistry on mouse samples at 1:100 (fig 7a) and in western blot on mouse samples at 1:1000 (fig 1b). Biochem Pharmacol (2016) ncbi
mouse monoclonal (7G6C5)
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology Hdac3 antibody (Cell Signaling, 3949P) was used in western blot on human samples at 1:1000 (fig 4). Cancer Sci (2015) ncbi
mouse monoclonal (7G6C5)
  • western blot; mouse; 1:1000
Cell Signaling Technology Hdac3 antibody (Cell Signaling, 3949) was used in western blot on mouse samples at 1:1000. Am J Physiol Heart Circ Physiol (2013) ncbi
BD Biosciences
mouse monoclonal (40/HDAC3)
  • western blot; human
BD Biosciences Hdac3 antibody (BD Biosciences, 611125) was used in western blot on human samples . PLoS ONE (2014) ncbi
Articles Reviewed
  1. Li M, Jiang H, Chen S, Ma Y. GATA binding protein 1 recruits histone deacetylase 2 to the promoter region of nuclear receptor binding protein 2 to affect the tumor microenvironment and malignancy of thyroid carcinoma. Bioengineered. 2022;13:11320-11341 pubmed publisher
  2. Huang S, Liu C, Wang Z, Fu Z, Britton W, Blomfield A, et al. REV-ERBα regulates age-related and oxidative stress-induced degeneration in retinal pigment epithelium via NRF2. Redox Biol. 2022;51:102261 pubmed publisher
  3. Yadav A, Huang T, Chen S, Ramasamy T, Hsueh Y, Lin S, et al. Sodium phenylbutyrate inhibits Schwann cell inflammation via HDAC and NFκB to promote axonal regeneration and remyelination. J Neuroinflammation. 2021;18:238 pubmed publisher
  4. Lo Cascio C, McNamara J, Melendez E, Lewis E, Dufault M, Sanai N, et al. Nonredundant, isoform-specific roles of HDAC1 in glioma stem cells. JCI Insight. 2021;6: pubmed publisher
  5. Lee M, Nam H, Kang H, Lee W, Lee G, Sung G, et al. Epigenetic regulation of p62/SQSTM1 overcomes the radioresistance of head and neck cancer cells via autophagy-dependent senescence induction. Cell Death Dis. 2021;12:250 pubmed publisher
  6. Xu S, Tao H, Cao W, Cao L, Lin Y, Zhao S, et al. Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis. Signal Transduct Target Ther. 2021;6:54 pubmed publisher
  7. Mia M, Cibi D, Abdul Ghani S, Song W, Tee N, Ghosh S, et al. YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction. PLoS Biol. 2020;18:e3000941 pubmed publisher
  8. Kuang Z, Wang Y, Li Y, Ye C, Ruhn K, Behrendt C, et al. The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3. Science. 2019;365:1428-1434 pubmed publisher
  9. Shi K, Yin X, Cai M, Yan Y, Jia C, Ma P, et al. PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors. elife. 2019;8: pubmed publisher
  10. Patel N, Wang J, Shiozawa K, Jones K, Zhang Y, Prokop J, et al. HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression. iScience. 2019;13:43-54 pubmed publisher
  11. Dai J, Huang Y, He X, Zhao M, Wang X, Liu Z, et al. Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity. Cell. 2019;: pubmed publisher
  12. Philips R, Lee J, Gaonkar K, Chanana P, Chung J, Romero Arocha S, et al. HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4+CD8+ thymocytes for CD4-lineage commitment. elife. 2019;8: pubmed publisher
  13. Żylicz J, Bousard A, Zumer K, Dossin F, Mohammad E, da Rocha S, et al. The Implication of Early Chromatin Changes in X Chromosome Inactivation. Cell. 2019;176:182-197.e23 pubmed publisher
  14. Bainor A, Saini S, Calderon A, Casado Polanco R, Giner Ramirez B, Moncada C, et al. The HDAC-Associated Sin3B Protein Represses DREAM Complex Targets and Cooperates with APC/C to Promote Quiescence. Cell Rep. 2018;25:2797-2807.e8 pubmed publisher
  15. Zhu Y, Wang G, Cingoz O, Goff S. NP220 mediates silencing of unintegrated retroviral DNA. Nature. 2018;564:278-282 pubmed publisher
  16. Lino Cardenas C, Kessinger C, Cheng Y, MacDonald C, Macgillivray T, Ghoshhajra B, et al. An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm. Nat Commun. 2018;9:1009 pubmed publisher
  17. Meng Z, Liu W, Xia Y, Yin H, Zhang C, Su D, et al. The pro-inflammatory signalling regulator Stat4 promotes vasculogenesis of great vessels derived from endothelial precursors. Nat Commun. 2017;8:14640 pubmed publisher
  18. Chakraborty K, Raundhal M, Chen B, Morse C, Tyurina Y, Khare A, et al. The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia. Nat Commun. 2017;8:13944 pubmed publisher
  19. Liu L, Guan H, Li Y, Ying Z, Wu J, Zhu X, et al. Astrocyte Elevated Gene 1 Interacts with Acetyltransferase p300 and c-Jun To Promote Tumor Aggressiveness. Mol Cell Biol. 2017;37: pubmed publisher
  20. Phelps M, Bailey J, Vleeshouwer Neumann T, Chen E. CRISPR screen identifies the NCOR/HDAC3 complex as a major suppressor of differentiation in rhabdomyosarcoma. Proc Natl Acad Sci U S A. 2016;113:15090-15095 pubmed publisher
  21. Hu B, Arpag S, Zuchner S, Li J. A novel missense mutation of CMT2P alters transcription machinery. Ann Neurol. 2016;80:834-845 pubmed publisher
  22. Romani B, Kamali Jamil R, Hamidi Fard M, Rahimi P, Momen S, Aghasadeghi M, et al. HIV-1 Vpr reactivates latent HIV-1 provirus by inducing depletion of class I HDACs on chromatin. Sci Rep. 2016;6:31924 pubmed publisher
  23. Chen W, Gao L, Wang J, Wang Y, Dong Z, Zhao J, et al. Conditional ablation of HDAC3 in islet beta cells results in glucose intolerance and enhanced susceptibility to STZ-induced diabetes. Oncotarget. 2016;7:57485-57497 pubmed publisher
  24. Nott A, Cheng J, Gao F, Lin Y, Gjoneska E, Ko T, et al. Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior. Nat Neurosci. 2016;19:1497-1505 pubmed publisher
  25. Lu R, Hu X, Zhou J, Sun J, Zhu A, Xu X, et al. COPS5 amplification and overexpression confers tamoxifen-resistance in ER?-positive breast cancer by degradation of NCoR. Nat Commun. 2016;7:12044 pubmed publisher
  26. Rando G, Tan C, Khaled N, Montagner A, Leuenberger N, Bertrand Michel J, et al. Glucocorticoid receptor-PPAR? axis in fetal mouse liver prepares neonates for milk lipid catabolism. elife. 2016;5: pubmed publisher
  27. Lin Y, Warren C, Li J, McKinsey T, Russell B. Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ. Cell Signal. 2016;28:1015-24 pubmed publisher
  28. Chaudhary S, Madhukrishna B, Adhya A, Keshari S, Mishra S. Overexpression of caspase 7 is ER? dependent to affect proliferation and cell growth in breast cancer cells by targeting p21(Cip). Oncogenesis. 2016;5:e219 pubmed publisher
  29. Dreer M, Fertey J, van de Poel S, Straub E, Madlung J, Macek B, et al. Interaction of NCOR/SMRT Repressor Complexes with Papillomavirus E8^E2C Proteins Inhibits Viral Replication. PLoS Pathog. 2016;12:e1005556 pubmed publisher
  30. Leus N, van der Wouden P, van den Bosch T, Hooghiemstra W, Ourailidou M, Kistemaker L, et al. HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity. Biochem Pharmacol. 2016;108:58-74 pubmed publisher
  31. Martínez Iglesias O, Alonso Merino E, Gómez Rey S, Velasco Martín J, Martín Orozco R, Luengo E, et al. Autoregulatory loop of nuclear corepressor 1 expression controls invasion, tumor growth, and metastasis. Proc Natl Acad Sci U S A. 2016;113:E328-37 pubmed publisher
  32. Huang R, Langdon S, Tse M, Mullen P, Um I, Faratian D, et al. The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer. Oncotarget. 2016;7:4695-711 pubmed publisher
  33. Liu X, Wang J, Li S, Li L, Huang M, Zhang Y, et al. Histone deacetylase 3 expression correlates with vasculogenic mimicry through the phosphoinositide3-kinase / ERK-MMP-laminin5γ2 signaling pathway. Cancer Sci. 2015;106:857-66 pubmed publisher
  34. Huichalaf C, Micheloni S, Ferri G, Caccia R, Gabellini D. DNA methylation analysis of the macrosatellite repeat associated with FSHD muscular dystrophy at single nucleotide level. PLoS ONE. 2014;9:e115278 pubmed publisher
  35. Joliot V, Ait Mohamed O, Battisti V, Pontis J, Philipot O, Robin P, et al. The SWI/SNF subunit/tumor suppressor BAF47/INI1 is essential in cell cycle arrest upon skeletal muscle terminal differentiation. PLoS ONE. 2014;9:e108858 pubmed publisher
  36. Blakeslee W, Wysoczynski C, Fritz K, Nyborg J, Churchill M, McKinsey T. Class I HDAC inhibition stimulates cardiac protein SUMOylation through a post-translational mechanism. Cell Signal. 2014;26:2912-20 pubmed publisher
  37. Jamaladdin S, Kelly R, O Regan L, Dovey O, Hodson G, Millard C, et al. Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells. Proc Natl Acad Sci U S A. 2014;111:9840-5 pubmed publisher
  38. Medford H, Porter K, Marsh S. Immediate effects of a single exercise bout on protein O-GlcNAcylation and chromatin regulation of cardiac hypertrophy. Am J Physiol Heart Circ Physiol. 2013;305:H114-23 pubmed publisher
  39. Isaacs J, Antony L, Dalrymple S, Brennen W, Gerber S, Hammers H, et al. Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment. Cancer Res. 2013;73:1386-99 pubmed publisher