This is a Validated Antibody Database (VAD) review about mouse Havcr1, based on 17 published articles (read how Labome selects the articles), using Havcr1 antibody in all methods. It is aimed to help Labome visitors find the most suited Havcr1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Havcr1 synonym: AI503787; KIM-1; TIM-1; Tim1; Timd1

R&D Systems
domestic goat polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig e4b
R&D Systems Havcr1 antibody (R&D, AF1817) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig e4b). Nature (2022) ncbi
domestic goat polyclonal
  • immunohistochemistry; mouse; 1:1000; fig 1a
R&D Systems Havcr1 antibody (RD Systems, AF1817) was used in immunohistochemistry on mouse samples at 1:1000 (fig 1a). Kidney360 (2021) ncbi
domestic goat polyclonal
  • immunohistochemistry; mouse; 1:500; loading ...; fig 2b
R&D Systems Havcr1 antibody (R&D, AF 1817) was used in immunohistochemistry on mouse samples at 1:500 (fig 2b). Front Pharmacol (2021) ncbi
domestic goat polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1c
R&D Systems Havcr1 antibody (R&D, AF1817) was used in western blot on mouse samples at 1:1000 (fig 1c). Clin Transl Med (2021) ncbi
domestic goat polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 13a
R&D Systems Havcr1 antibody (R&D Systems, AF1817) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 13a). Front Pharmacol (2020) ncbi
domestic goat polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2f
R&D Systems Havcr1 antibody (R&D systems, AF1817) was used in western blot on mouse samples at 1:1000 (fig 2f). Cell Death Dis (2021) ncbi
domestic goat polyclonal
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1a
R&D Systems Havcr1 antibody (R&D Systems, AF1817) was used in immunohistochemistry - paraffin section on mouse samples (fig 1a). Sci Rep (2021) ncbi
domestic goat polyclonal
  • immunohistochemistry; mouse; loading ...; fig 8f
R&D Systems Havcr1 antibody (R&D Systems, AF1817) was used in immunohistochemistry on mouse samples (fig 8f). J Clin Invest (2019) ncbi
domestic goat polyclonal
  • immunohistochemistry; mouse; 1:800; loading ...; fig 4b
  • western blot; mouse; loading ...; fig 2d
R&D Systems Havcr1 antibody (R&D Systems, AF1817) was used in immunohistochemistry on mouse samples at 1:800 (fig 4b) and in western blot on mouse samples (fig 2d). J Clin Invest (2019) ncbi
domestic goat polyclonal
  • immunohistochemistry - paraffin section; mouse; fig 6
In order to study the reversal of renal injury and high blood pressure by renal rescue of dopamine D2 receptor function, R&D Systems Havcr1 antibody (R&D Systems, AF1817) was used in immunohistochemistry - paraffin section on mouse samples (fig 6). JCI Insight (2016) ncbi
domestic goat polyclonal
  • immunohistochemistry; mouse; fig 5d
  • western blot; mouse; fig 6f
In order to elucidate sonoporation and its role in gene transfer in regards to kidneys, R&D Systems Havcr1 antibody (R&D Systems, AF1817) was used in immunohistochemistry on mouse samples (fig 5d) and in western blot on mouse samples (fig 6f). Mol Ther (2016) ncbi
Invitrogen
rat monoclonal (RMT1-4)
  • flow cytometry; mouse; loading ...; fig 2b
In order to explore the contribution of natural killer and natural killer T cells In B regulatory cell-induced tolerance, Invitrogen Havcr1 antibody (eBioscience, RMT1-4) was used in flow cytometry on mouse samples (fig 2b). Am J Transplant (2017) ncbi
rat monoclonal (RMT1-4)
In order to study apoptosis inhibitor of macrophage protein, intraluminal debris clearance and acute kidney injury in mice, Invitrogen Havcr1 antibody (eBioscience, RMT1-4) was used . Nat Med (2016) ncbi
rat monoclonal (RMT1-4)
  • flow cytometry; mouse; loading ...; fig 4d
In order to determine if specific B cell subsets or if B cell-derived interleukin-10 contributes to tolerance, Invitrogen Havcr1 antibody (eBioscience, RMT1-4) was used in flow cytometry on mouse samples (fig 4d). Transplantation (2015) ncbi
rat monoclonal (RMT1-4)
  • flow cytometry; mouse; fig s1
In order to test if blocking several checkpoint receptors boosts anti-tumor immunity in a low-dose, lymphodepleting whole body radiation model, Invitrogen Havcr1 antibody (eBioscience, RMT1-4) was used in flow cytometry on mouse samples (fig s1). J Immunother Cancer (2015) ncbi
BioLegend
rat monoclonal (RMT1-4)
  • flow cytometry; mouse; fig 1a
In order to elucidate how schistosome-induced B cells protect against allergic airway inflammation, BioLegend Havcr1 antibody (Biolegend, RMT1-4) was used in flow cytometry on mouse samples (fig 1a). Int J Parasitol (2017) ncbi
rat monoclonal (RMT1-4)
  • flow cytometry; mouse; loading ...; fig s2a
In order to research the role of Tim-1 and Tim-4 blockade in the atherosclerotic pathogenesis, BioLegend Havcr1 antibody (Biolegend, RMT1-4) was used in flow cytometry on mouse samples (fig s2a). Arterioscler Thromb Vasc Biol (2016) ncbi
Bio X Cell
rat monoclonal (RMT1-10)
  • blocking or activating experiments; mouse; loading ...; fig 1
In order to explore the contribution of natural killer and natural killer T cells In B regulatory cell-induced tolerance, Bio X Cell Havcr1 antibody (BioXCell, RMT1-10) was used in blocking or activating experiments on mouse samples (fig 1). Am J Transplant (2017) ncbi
Bio-Rad
rat monoclonal (RMT1-10)
  • immunohistochemistry; human; loading ...; fig 4a
  • immunocytochemistry; mouse; loading ...; fig 3e
  • immunohistochemistry; mouse; loading ...; fig 4a
In order to study apoptosis inhibitor of macrophage protein, intraluminal debris clearance and acute kidney injury in mice, Bio-Rad Havcr1 antibody (AbDSerotec, RMT1-10) was used in immunohistochemistry on human samples (fig 4a), in immunocytochemistry on mouse samples (fig 3e) and in immunohistochemistry on mouse samples (fig 4a). Nat Med (2016) ncbi
Articles Reviewed
  1. Mishima E, Ito J, Wu Z, Nakamura T, Wahida A, Doll S, et al. A non-canonical vitamin K cycle is a potent ferroptosis suppressor. Nature. 2022;608:778-783 pubmed publisher
  2. Ranea Robles P, Portman K, Bender A, Lee K, He J, Mulholland D, et al. Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice. Kidney360. 2021;2:1441-1454 pubmed publisher
  3. Marquez Exposito L, Tejedor Santamaria L, Santos Sánchez L, Valentijn F, Cantero Navarro E, Rayego Mateos S, et al. Acute Kidney Injury is Aggravated in Aged Mice by the Exacerbation of Proinflammatory Processes. Front Pharmacol. 2021;12:662020 pubmed publisher
  4. Yang Y, Cai F, Zhou N, Liu S, Wang P, Zhang S, et al. Dimethyl fumarate prevents ferroptosis to attenuate acute kidney injury by acting on NRF2. Clin Transl Med. 2021;11:e382 pubmed publisher
  5. Alawi L, Dhakal S, Emberesh S, Sawant H, Hosawi A, Thanekar U, et al. Effects of Angiotensin II Type 1A Receptor on ACE2, Neprilysin and KIM-1 in Two Kidney One Clip (2K1C) Model of Renovascular Hypertension. Front Pharmacol. 2020;11:602985 pubmed publisher
  6. Xia W, Li Y, Wu M, Jin Q, Wang Q, Li S, et al. Gasdermin E deficiency attenuates acute kidney injury by inhibiting pyroptosis and inflammation. Cell Death Dis. 2021;12:139 pubmed publisher
  7. Arita M, Watanabe S, Aoki N, Kuwahara S, Suzuki R, Goto S, et al. Combination therapy of cisplatin with cilastatin enables an increased dose of cisplatin, enhancing its antitumor effect by suppression of nephrotoxicity. Sci Rep. 2021;11:750 pubmed publisher
  8. Ying W, Li X, Rangarajan S, Feng W, Curtis L, Sanders P. Immunoglobulin light chains generate proinflammatory and profibrotic kidney injury. J Clin Invest. 2019;129:2792-2806 pubmed publisher
  9. Li L, Kang H, Zhang Q, D Agati V, Al Awqati Q, Lin F. FoxO3 activation in hypoxic tubules prevents chronic kidney disease. J Clin Invest. 2019;129:2374-2389 pubmed publisher
  10. van der Vlugt L, Obieglo K, Ozir Fazalalikhan A, Sparwasser T, Haeberlein S, Smits H. Schistosome-induced pulmonary B cells inhibit allergic airway inflammation and display a reduced Th2-driving function. Int J Parasitol. 2017;47:545-554 pubmed publisher
  11. Schuetz C, Lee K, Scott R, Kojima L, Washburn L, Liu L, et al. Regulatory B Cell-Dependent Islet Transplant Tolerance Is Also Natural Killer Cell Dependent. Am J Transplant. 2017;17:1656-1662 pubmed publisher
  12. Konkalmatt P, Asico L, Zhang Y, Yang Y, Drachenberg C, Zheng X, et al. Renal rescue of dopamine D2 receptor function reverses renal injury and high blood pressure. JCI Insight. 2016;1: pubmed
  13. Foks A, Engelbertsen D, Kuperwaser F, Alberts Grill N, Gonen A, Witztum J, et al. Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice. Arterioscler Thromb Vasc Biol. 2016;36:456-65 pubmed publisher
  14. Arai S, Kitada K, Yamazaki T, Takai R, Zhang X, Tsugawa Y, et al. Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice. Nat Med. 2016;22:183-93 pubmed publisher
  15. Ishida R, Kami D, Kusaba T, Kirita Y, Kishida T, Mazda O, et al. Kidney-specific Sonoporation-mediated Gene Transfer. Mol Ther. 2016;24:125-34 pubmed publisher
  16. Lal G, Nakayama Y, Sethi A, Singh A, Burrell B, Kulkarni N, et al. Interleukin-10 From Marginal Zone Precursor B-Cell Subset Is Required for Costimulatory Blockade-Induced Transplantation Tolerance. Transplantation. 2015;99:1817-28 pubmed publisher
  17. Jing W, Gershan J, Weber J, Tlomak D, McOlash L, Sabatos Peyton C, et al. Combined immune checkpoint protein blockade and low dose whole body irradiation as immunotherapy for myeloma. J Immunother Cancer. 2015;3:2 pubmed publisher