This is a Validated Antibody Database (VAD) review about mouse Grin2a, based on 23 published articles (read how Labome selects the articles), using Grin2a antibody in all methods. It is aimed to help Labome visitors find the most suited Grin2a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Grin2a synonym: GluN2A; GluRepsilon1; NMDAR2A; NR2A

Abcam
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2d
Abcam Grin2a antibody (Abcam, ab203197) was used in western blot on mouse samples at 1:1000 (fig 2d). Front Neurosci (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:50; loading ...; fig s1a
Abcam Grin2a antibody (Abcam, ab16646) was used in immunohistochemistry on mouse samples at 1:50 (fig s1a). Front Neurosci (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2d
Abcam Grin2a antibody (Abcam, ab106590) was used in western blot on mouse samples at 1:1000 (fig 2d). Front Neurosci (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4a
Abcam Grin2a antibody (Abcam, ab16646) was used in western blot on mouse samples at 1:1000 (fig 4a). Front Pharmacol (2020) ncbi
domestic rabbit monoclonal (EPR2465(2))
  • western blot; rat; 1:500; fig 5
Abcam Grin2a antibody (Abcam, ab124913) was used in western blot on rat samples at 1:500 (fig 5). Sci Rep (2016) ncbi
domestic rabbit monoclonal (EPR2465(2))
  • western blot; mouse; fig 5
Abcam Grin2a antibody (Abcam, ab124913) was used in western blot on mouse samples (fig 5). Physiol Rep (2016) ncbi
domestic rabbit monoclonal (EPR7063)
  • western blot; mouse; loading ...; fig 2b
Abcam Grin2a antibody (Abcam, ab133265) was used in western blot on mouse samples (fig 2b). EBioMedicine (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5d
Invitrogen Grin2a antibody (Invitrogen, A6473) was used in western blot on mouse samples at 1:1000 (fig 5d). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 3a
In order to show protein disulfide isomerases bind to N-methyl-D-aspartate receptor in the normal hippocampus, and that this binding is increased in chronic epileptic rats, Invitrogen Grin2a antibody (Thermo Fisher, OPA1-04021) was used in western blot on rat samples at 1:1000 (fig 3a). Sci Rep (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; fig 2
In order to propose that SALM4 negatively regulates excitatory synapses via inhibition of SALM3-LAR adhesion, Invitrogen Grin2a antibody (Invitrogen, A-6473) was used in western blot on mouse samples at 1:500 (fig 2). Nat Commun (2016) ncbi
domestic rabbit polyclonal
In order to assess how rabphilin 3A retains NMDA receptors through interaction with GluN2A/PSD-95 complex synapse sites, Invitrogen Grin2a antibody (Invitrogen, 480031) was used . Nat Commun (2015) ncbi
domestic rabbit polyclonal
In order to study translocated genes, MIZ-type containing 1 and proline-rich 12, Invitrogen Grin2a antibody (Invitrogen, 480031) was used . Neurogenetics (2015) ncbi
domestic rabbit polyclonal
In order to study the effect of copper exposure on memory, Invitrogen Grin2a antibody (Molecular Probes/Invitrogen, A-6473) was used . J Alzheimers Dis (2015) ncbi
Alomone Labs
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:1000; loading ...; fig 2c
Alomone Labs Grin2a antibody (Alomone, AGC-002) was used in immunohistochemistry on human samples at 1:1000 (fig 2c). Sci Rep (2021) ncbi
domestic rabbit polyclonal
  • other; mouse; 1:200; loading ...; fig 1b
Alomone Labs Grin2a antibody (alomone laboratories, AGC-002) was used in other on mouse samples at 1:200 (fig 1b). Aging Cell (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - free floating section; mouse; 1:500; loading ...; fig 8e
Alomone Labs Grin2a antibody (Alamone, AGC-002) was used in immunohistochemistry - free floating section on mouse samples at 1:500 (fig 8e). Front Neurosci (2019) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:100; loading ...; fig s2
Alomone Labs Grin2a antibody (Alomone Labs, AGC-002) was used in immunocytochemistry on mouse samples at 1:100 (fig s2). Diabetes (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal
  • western blot; human; 1:500; loading ...; fig 2c
Santa Cruz Biotechnology Grin2a antibody (Santa Cruz, sc-515148) was used in western blot on human samples at 1:500 (fig 2c). Cell Div (2020) ncbi
mouse monoclonal (D-8)
  • western blot; mouse; 1:500; fig 4
Santa Cruz Biotechnology Grin2a antibody (Santa Cruz, sc-390094) was used in western blot on mouse samples at 1:500 (fig 4). Front Cell Neurosci (2015) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1b, s1g
Cell Signaling Technology Grin2a antibody (Cell Signaling, 4205) was used in western blot on mouse samples (fig 1b, s1g). Sci Adv (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig 5f
Cell Signaling Technology Grin2a antibody (CST, 4205) was used in western blot on mouse samples at 1:2000 (fig 5f). elife (2022) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 4d
Cell Signaling Technology Grin2a antibody (Cell Signaling, 4205S) was used in western blot on human samples at 1:1000 (fig 4d). Nat Neurosci (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 1
Cell Signaling Technology Grin2a antibody (Cell Signaling Tech, 4205) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 6b
Cell Signaling Technology Grin2a antibody (Cell Signaling Technology, 4205) was used in western blot on rat samples at 1:1000 (fig 6b). Sci Rep (2016) ncbi
BD Biosciences
mouse monoclonal (5/NMDAR2A)
  • western blot; mouse; fig 5
In order to analyze selective partitioning into complexes and supercomplexes during synapse maturation by NMDA receptors, BD Biosciences Grin2a antibody (BD Biosciences, 612286) was used in western blot on mouse samples (fig 5). Nat Commun (2016) ncbi
Articles Reviewed
  1. Azarnia Tehran D, Kochlamazashvili G, Pampaloni N, Sposini S, Shergill J, Lehmann M, et al. Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity. Sci Adv. 2022;8:eabl5032 pubmed publisher
  2. Zheng R, Du Y, Wang X, Liao T, Zhang Z, Wang N, et al. KIF2C regulates synaptic plasticity and cognition in mice through dynamic microtubule depolymerization. elife. 2022;11: pubmed publisher
  3. Wang Y, Han J, Zhu J, Zhang M, Ju M, Du Y, et al. GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity. Front Neurosci. 2021;15:703044 pubmed publisher
  4. Dong Y, Hsu F, Koziol White C, Stepanova V, Jude J, Gritsiuta A, et al. Functional NMDA receptors are expressed by human pulmonary artery smooth muscle cells. Sci Rep. 2021;11:8205 pubmed publisher
  5. Gordon A, Yoon S, Tran S, Makinson C, Park J, Andersen J, et al. Long-term maturation of human cortical organoids matches key early postnatal transitions. Nat Neurosci. 2021;24:331-342 pubmed publisher
  6. Al Abed A, Sellami A, Potier M, Ducourneau E, Gerbeaud Lassau P, Brayda Bruno L, et al. Age-related impairment of declarative memory: linking memorization of temporal associations to GluN2B redistribution in dorsal CA1. Aging Cell. 2020;19:e13243 pubmed publisher
  7. Tan Y, Xu Y, Cheng C, Zheng C, Zeng W, Wang J, et al. LY354740 Reduces Extracellular Glutamate Concentration, Inhibits Phosphorylation of Fyn/NMDARs, and Expression of PLK2/pS129 α-Synuclein in Mice Treated With Acute or Sub-Acute MPTP. Front Pharmacol. 2020;11:183 pubmed publisher
  8. Dong C, Zhang J, Fang S, Liu F. IGFBP5 increases cell invasion and inhibits cell proliferation by EMT and Akt signaling pathway in Glioblastoma multiforme cells. Cell Div. 2020;15:4 pubmed publisher
  9. Yeung J, Palpagama T, Tate W, Peppercorn K, Waldvogel H, Faull R, et al. The Acute Effects of Amyloid-Beta1-42 on Glutamatergic Receptor and Transporter Expression in the Mouse Hippocampus. Front Neurosci. 2019;13:1427 pubmed publisher
  10. Sclip A, Sudhof T. LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses. elife. 2020;9: pubmed publisher
  11. Kim J, Ko A, Hyun H, Min S, Kim J. PDI regulates seizure activity via NMDA receptor redox in rats. Sci Rep. 2017;7:42491 pubmed publisher
  12. Lie E, Ko J, Choi S, Roh J, Cho Y, Noh R, et al. SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion. Nat Commun. 2016;7:12328 pubmed publisher
  13. Pan B, Huang X, Deng C. Chronic administration of aripiprazole activates GSK3β-dependent signalling pathways, and up-regulates GABAA receptor expression and CREB1 activity in rats. Sci Rep. 2016;6:30040 pubmed publisher
  14. Chandler J, Wongtrakool C, Banton S, Li S, Orr M, Barr D, et al. Low-dose oral cadmium increases airway reactivity and lung neuronal gene expression in mice. Physiol Rep. 2016;4: pubmed publisher
  15. Roshanravan H, Kim E, Dryer S. NMDA Receptors as Potential Therapeutic Targets in Diabetic Nephropathy: Increased Renal NMDA Receptor Subunit Expression in Akita Mice and Reduced Nephropathy Following Sustained Treatment With Memantine or MK-801. Diabetes. 2016;65:3139-50 pubmed publisher
  16. Emanuele M, Esposito A, Camerini S, Antonucci F, Ferrara S, Seghezza S, et al. Exogenous Alpha-Synuclein Alters Pre- and Post-Synaptic Activity by Fragmenting Lipid Rafts. EBioMedicine. 2016;7:191-204 pubmed publisher
  17. Zhang H, Kang E, Wang Y, Yang C, Yu H, Wang Q, et al. Brain-specific Crmp2 deletion leads to neuronal development deficits and behavioural impairments in mice. Nat Commun. 2016;7: pubmed publisher
  18. Zhao T, Li C, Wei W, Zhang H, Ma D, Song X, et al. Prenatal ketamine exposure causes abnormal development of prefrontal cortex in rat. Sci Rep. 2016;6:26865 pubmed publisher
  19. Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed publisher
  20. Stanic J, Carta M, Eberini I, Pelucchi S, Marcello E, Genazzani A, et al. Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex. Nat Commun. 2015;6:10181 pubmed publisher
  21. Brai E, Marathe S, Astori S, Fredj N, Perry E, Lamy C, et al. Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling. Front Cell Neurosci. 2015;9:447 pubmed publisher
  22. Córdova Fletes C, Domínguez M, Delint Ramirez I, Martínez Rodríguez H, Rivas Estilla A, Barros Núñez P, et al. A de novo t(10;19)(q22.3;q13.33) leads to ZMIZ1/PRR12 reciprocal fusion transcripts in a girl with intellectual disability and neuropsychiatric alterations. Neurogenetics. 2015;16:287-98 pubmed publisher
  23. Ma Q, Ying M, Sui X, Zhang H, Huang H, Yang L, et al. Chronic copper exposure causes spatial memory impairment, selective loss of hippocampal synaptic proteins, and activation of PKR/eIF2α pathway in mice. J Alzheimers Dis. 2015;43:1413-27 pubmed publisher