This is a Validated Antibody Database (VAD) review about mouse Gpx4, based on 15 published articles (read how Labome selects the articles), using Gpx4 antibody in all methods. It is aimed to help Labome visitors find the most suited Gpx4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Gpx4 synonym: GPx-4; GSHPx-4; PHGPx; mtPHGPx; snGPx

Abcam
domestic rabbit monoclonal (EPNCIR144)
  • western blot; mouse; 1:500; loading ...; fig 1c
Abcam Gpx4 antibody (Abcam, ab125066) was used in western blot on mouse samples at 1:500 (fig 1c). Nat Chem Biol (2020) ncbi
domestic rabbit monoclonal (EPNCIR144)
  • western blot; mouse; loading ...; fig s3
Abcam Gpx4 antibody (Abcam, ab125066) was used in western blot on mouse samples (fig s3). Sci Adv (2019) ncbi
domestic rabbit monoclonal (EPNCIR144)
  • western blot; human; 1:2000; loading ...; fig s1c
Abcam Gpx4 antibody (Abcam, ab125066) was used in western blot on human samples at 1:2000 (fig s1c). Atherosclerosis (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig e10e
Abcam Gpx4 antibody (Abcam, ab41787) was used in western blot on human samples (fig e10e). Nature (2019) ncbi
domestic rabbit monoclonal (EPNCIR144)
  • western blot; human; 1:250; loading ...; fig 2j
Abcam Gpx4 antibody (Abcam, ab125066) was used in western blot on human samples at 1:250 (fig 2j). Cell Chem Biol (2019) ncbi
domestic rabbit monoclonal (EPNCIR144)
  • western blot; human; loading ...; fig 6a
  • western blot; rat; loading ...; fig 6a
Abcam Gpx4 antibody (Abcam, ab125066) was used in western blot on human samples (fig 6a) and in western blot on rat samples (fig 6a). Cancer Lett (2018) ncbi
domestic rabbit monoclonal (EPNCIR144)
  • immunohistochemistry - paraffin section; mouse; 1:250; fig 2d
  • western blot; mouse; fig 2b
Abcam Gpx4 antibody (Abcam, 125066) was used in immunohistochemistry - paraffin section on mouse samples at 1:250 (fig 2d) and in western blot on mouse samples (fig 2b). Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig ex7a
Abcam Gpx4 antibody (Abcam, ab41787) was used in western blot on human samples at 1:1000 (fig ex7a). Nature (2017) ncbi
domestic rabbit monoclonal (EPNCIR144)
  • western blot; human; 1:1000; loading ...; fig 4b
Abcam Gpx4 antibody (Abcam, ab125066) was used in western blot on human samples at 1:1000 (fig 4b). Nat Chem Biol (2017) ncbi
domestic rabbit monoclonal (EPNCIR144)
  • western blot; mouse; 1:500; loading ...; fig s1c
Abcam Gpx4 antibody (Abcam, ab125066) was used in western blot on mouse samples at 1:500 (fig s1c). Nat Chem Biol (2017) ncbi
domestic rabbit monoclonal (EPNCIR144)
  • western blot; human; 1:1000; loading ...; fig 5
In order to report polyphenols with iron-chelating potential, Abcam Gpx4 antibody (Abcam, AB125066) was used in western blot on human samples at 1:1000 (fig 5). Mol Nutr Food Res (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 1
Abcam Gpx4 antibody (abcam, ab41787) was used in western blot on human samples (fig 1). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (EPNCIR144)
  • western blot; human; loading ...; fig s14a
Abcam Gpx4 antibody (AbCam, ab125066) was used in western blot on human samples (fig s14a). Cell Death Dis (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:2000; fig s6c
Abcam Gpx4 antibody (Abcam, ab41787) was used in western blot on human samples at 1:2000 (fig s6c). Nat Chem Biol (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-12)
  • flow cytometry; mouse; loading ...; fig s1c
Santa Cruz Biotechnology Gpx4 antibody (Santa, sc-166120) was used in flow cytometry on mouse samples (fig s1c). Nat Chem Biol (2020) ncbi
mouse monoclonal (B-12)
  • western blot; mouse; loading ...; fig 3a
Santa Cruz Biotechnology Gpx4 antibody (Santa, sc-166120) was used in western blot on mouse samples (fig 3a). Biology (Basel) (2019) ncbi
Articles Reviewed
  1. Kapralov A, Yang Q, Dar H, Tyurina Y, Anthonymuthu T, Kim R, et al. Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death. Nat Chem Biol. 2020;16:278-290 pubmed publisher
  2. Yang M, Chen P, Liu J, Zhu S, Kroemer G, Klionsky D, et al. Clockophagy is a novel selective autophagy process favoring ferroptosis. Sci Adv. 2019;5:eaaw2238 pubmed publisher
  3. Eleftheriadis T, Pissas G, Liakopoulos V, Stefanidis I. Factors that May Protect the Native Hibernator Syrian Hamster Renal Tubular Epithelial Cells from Ferroptosis Due to Warm Anoxia-Reoxygenation. Biology (Basel). 2019;8: pubmed publisher
  4. Zhu Y, Zhang Y, Huang X, Xie Y, Qu Y, Long H, et al. Z-Ligustilide protects vascular endothelial cells from oxidative stress and rescues high fat diet-induced atherosclerosis by activating multiple NRF2 downstream genes. Atherosclerosis. 2019;284:110-120 pubmed publisher
  5. Garcia Bermudez J, Baudrier L, Bayraktar E, Shen Y, La K, Guarecuco R, et al. Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death. Nature. 2019;567:118-122 pubmed publisher
  6. Magtanong L, Ko P, To M, Cao J, Forcina G, Tarangelo A, et al. Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State. Cell Chem Biol. 2019;26:420-432.e9 pubmed publisher
  7. Wang Z, Ding Y, Wang X, Lu S, Wang C, He C, et al. Pseudolaric acid B triggers ferroptosis in glioma cells via activation of Nox4 and inhibition of xCT. Cancer Lett. 2018;428:21-33 pubmed publisher
  8. Ingold I, Berndt C, Schmitt S, Doll S, Poschmann G, Buday K, et al. Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis. Cell. 2018;172:409-422.e21 pubmed publisher
  9. Viswanathan V, Ryan M, Dhruv H, Gill S, Eichhoff O, Seashore Ludlow B, et al. Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway. Nature. 2017;547:453-457 pubmed publisher
  10. Doll S, Proneth B, Tyurina Y, Panzilius E, Kobayashi S, Ingold I, et al. ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. Nat Chem Biol. 2017;13:91-98 pubmed publisher
  11. Kagan V, Mao G, Qu F, Angeli J, Doll S, Croix C, et al. Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. Nat Chem Biol. 2017;13:81-90 pubmed publisher
  12. Horniblow R, Henesy D, Iqbal T, Tselepis C. Modulation of iron transport, metabolism and reactive oxygen status by quercetin-iron complexes in vitro. Mol Nutr Food Res. 2017;61: pubmed publisher
  13. Yang W, Kim K, Gaschler M, Patel M, Shchepinov M, Stockwell B. Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis. Proc Natl Acad Sci U S A. 2016;113:E4966-75 pubmed publisher
  14. Ma S, Henson E, Chen Y, Gibson S. Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells. Cell Death Dis. 2016;7:e2307 pubmed publisher
  15. Shimada K, Skouta R, Kaplan A, Yang W, Hayano M, Dixon S, et al. Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis. Nat Chem Biol. 2016;12:497-503 pubmed publisher