This is a Validated Antibody Database (VAD) review about mouse Gnai2, based on 10 published articles (read how Labome selects the articles), using Gnai2 antibody in all methods. It is aimed to help Labome visitors find the most suited Gnai2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Gnai2 synonym: C76432; Galphai2; Gia; Gnai-2

Knockout validation
Abcam
domestic rabbit monoclonal (EPR9469)
  • western blot knockout validation; mouse; 1:5000; fig 2
  • western blot; human; 1:5000; fig 2
Abcam Gnai2 antibody (Abcam, ab157204) was used in western blot knockout validation on mouse samples at 1:5000 (fig 2) and in western blot on human samples at 1:5000 (fig 2). Sci Rep (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (L5)
  • immunohistochemistry - frozen section; rat; loading ...; fig 2b
  • western blot; rat; fig 2e
Santa Cruz Biotechnology Gnai2 antibody (Santa Cruz, sc-13534) was used in immunohistochemistry - frozen section on rat samples (fig 2b) and in western blot on rat samples (fig 2e). J Neuroinflammation (2022) ncbi
mouse monoclonal (L5)
  • immunocytochemistry; human; loading ...; fig 7a
  • western blot; human; loading ...; fig 2d
Santa Cruz Biotechnology Gnai2 antibody (Santa Cruz Biotechnology, sc-13534) was used in immunocytochemistry on human samples (fig 7a) and in western blot on human samples (fig 2d). Biol Open (2019) ncbi
mouse monoclonal (35)
  • immunoprecipitation; mouse; fig 7
Santa Cruz Biotechnology Gnai2 antibody (Santa Cruz Biotechnology, sc-136478) was used in immunoprecipitation on mouse samples (fig 7). Nat Commun (2016) ncbi
mouse monoclonal (L5)
  • western blot; human
In order to study the role of gep oncogenes in ovarian cancer growth, Santa Cruz Biotechnology Gnai2 antibody (Santa Cruz Biotechnology, sc-13534) was used in western blot on human samples . Genes Cancer (2015) ncbi
mouse monoclonal (L5)
  • western blot; mouse; fig 2d
In order to investigate the role of GNB1 and GNB2 in cancer cells., Santa Cruz Biotechnology Gnai2 antibody (Santa Cruz, sc-13534) was used in western blot on mouse samples (fig 2d). Nat Med (2015) ncbi
mouse monoclonal (L5)
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 1
Santa Cruz Biotechnology Gnai2 antibody (Santa Cruz, sc-13534) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 1). Cancer Lett (2015) ncbi
mouse monoclonal (L5)
  • western blot; human
Santa Cruz Biotechnology Gnai2 antibody (Santa Cruz Biotechnology, sc-13534) was used in western blot on human samples . Pigment Cell Melanoma Res (2013) ncbi
Abcam
domestic rabbit monoclonal (EPR9469)
  • western blot; mouse; 1:5000; loading ...; fig 9a
Abcam Gnai2 antibody (Abcam, ab157204) was used in western blot on mouse samples at 1:5000 (fig 9a). Nat Commun (2021) ncbi
domestic rabbit monoclonal (EPR9469)
  • western blot knockout validation; mouse; 1:5000; fig 2
  • western blot; human; 1:5000; fig 2
Abcam Gnai2 antibody (Abcam, ab157204) was used in western blot knockout validation on mouse samples at 1:5000 (fig 2) and in western blot on human samples at 1:5000 (fig 2). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1 ug/ml; fig 3b
Abcam Gnai2 antibody (Abcam, ab3522) was used in western blot on human samples at 1 ug/ml (fig 3b). Nat Commun (2016) ncbi
Articles Reviewed
  1. Lan T, Wu Y, Zhang Y, Li S, Zhu Z, Wang L, et al. Agomelatine rescues lipopolysaccharide-induced neural injury and depression-like behaviors via suppression of the Gαi-2-PKA-ASK1 signaling pathway. J Neuroinflammation. 2022;19:117 pubmed publisher
  2. Chen X, Yuan J, Xue G, Campanario S, Wang D, Wang W, et al. Translational control by DHX36 binding to 5'UTR G-quadruplex is essential for muscle stem-cell regenerative functions. Nat Commun. 2021;12:5043 pubmed publisher
  3. Xiong X, Lee C, Li W, Yu J, Zhu L, Kim Y, et al. Acid Sphingomyelinase regulates the localization and trafficking of palmitoylated proteins. Biol Open. 2019;: pubmed publisher
  4. Bissinger R, Lang E, Ghashghaeinia M, Singh Y, Zelenak C, Fehrenbacher B, et al. Blunted apoptosis of erythrocytes in mice deficient in the heterotrimeric G-protein subunit Gαi2. Sci Rep. 2016;6:30925 pubmed publisher
  5. Yuan X, Cao J, He X, Serra R, Qu J, Cao X, et al. Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation. Nat Commun. 2016;7:11024 pubmed publisher
  6. Doi M, Murai I, Kunisue S, Setsu G, Uchio N, Tanaka R, et al. Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour. Nat Commun. 2016;7:10583 pubmed publisher
  7. Ha J, Gomathinayagam R, Yan M, Jayaraman M, Ramesh R, Dhanasekaran D. Determinant role for the gep oncogenes, Gα12/13, in ovarian cancer cell proliferation and xenograft tumor growth. Genes Cancer. 2015;6:356-364 pubmed
  8. Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, et al. Mutations in G protein β subunits promote transformation and kinase inhibitor resistance. Nat Med. 2015;21:71-5 pubmed publisher
  9. Ward J, Ha J, Jayaraman M, Dhanasekaran D. LPA-mediated migration of ovarian cancer cells involves translocalization of Gαi2 to invadopodia and association with Src and β-pix. Cancer Lett. 2015;356:382-91 pubmed publisher
  10. Devi S, Markandeya Y, Maddodi N, Dhingra A, Vardi N, Balijepalli R, et al. Metabotropic glutamate receptor 6 signaling enhances TRPM1 calcium channel function and increases melanin content in human melanocytes. Pigment Cell Melanoma Res. 2013;26:348-56 pubmed publisher