This is a Validated Antibody Database (VAD) review about mouse Gm20746, based on 12 published articles (read how Labome selects the articles), using Gm20746 antibody in all methods. It is aimed to help Labome visitors find the most suited Gm20746 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Abcam
rabbit monoclonal (EPR5260)
  • immunohistochemistry knockout validation; mouse; fig 3
  • western blot knockout validation; mouse; fig 4
  • immunohistochemistry - paraffin section; mouse; fig 3
In order to use Fth and Ftl knock out mice to study iron metabolism in the brain, Abcam Gm20746 antibody (Abcam, ab109373) was used in immunohistochemistry knockout validation on mouse samples (fig 3), in western blot knockout validation on mouse samples (fig 4) and in immunohistochemistry - paraffin section on mouse samples (fig 3). PLoS ONE (2015) ncbi
Abcam
rabbit polyclonal
  • western blot; rat; loading ...; fig 2e
  • western blot; human; loading ...; fig 2e
Abcam Gm20746 antibody (Abcam, ab69090) was used in western blot on rat samples (fig 2e) and in western blot on human samples (fig 2e). Cancer Lett (2018) ncbi
rabbit polyclonal
  • western blot; human; 1:5000; loading ...; fig 5
In order to report polyphenols with iron-chelating potential, Abcam Gm20746 antibody (Abcam, AB69090) was used in western blot on human samples at 1:5000 (fig 5). Mol Nutr Food Res (2017) ncbi
rabbit polyclonal
  • immunohistochemistry; human; fig 2D
In order to report the transcriptomes of thousands of single pancreatic cells, Abcam Gm20746 antibody (Abcam, ab69090) was used in immunohistochemistry on human samples (fig 2D). Cell Syst (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 7a
In order to develop StemID, an algorithm for identifying stem cells among all detectable cell types within a population, Abcam Gm20746 antibody (Abcam, ab69090) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 7a). Cell Stem Cell (2016) ncbi
rabbit monoclonal (EPR5260)
  • immunohistochemistry knockout validation; mouse; fig 3
  • western blot knockout validation; mouse; fig 4
  • immunohistochemistry - paraffin section; mouse; fig 3
In order to use Fth and Ftl knock out mice to study iron metabolism in the brain, Abcam Gm20746 antibody (Abcam, ab109373) was used in immunohistochemistry knockout validation on mouse samples (fig 3), in western blot knockout validation on mouse samples (fig 4) and in immunohistochemistry - paraffin section on mouse samples (fig 3). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human
Abcam Gm20746 antibody (Abcam, ab69090) was used in western blot on human samples . J Biol Chem (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - free floating section; mouse; 1:250
  • immunohistochemistry - free floating section; human; 1:250
Abcam Gm20746 antibody (Abcam, 69090) was used in immunohistochemistry - free floating section on mouse samples at 1:250 and in immunohistochemistry - free floating section on human samples at 1:250. Acta Neuropathol Commun (2013) ncbi
rabbit polyclonal
  • western blot; mouse
Abcam Gm20746 antibody (Abcam, ab69090) was used in western blot on mouse samples . Anal Biochem (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-1)
  • western blot; human; 1:1000; loading ...; fig 4b
In order to study the role of mitochondrial ferritin protein in iron-dependent cell death (ferroptosis)., Santa Cruz Biotechnology Gm20746 antibody (Santa Cruz, sc-390558) was used in western blot on human samples at 1:1000 (fig 4b). Front Aging Neurosci (2016) ncbi
mouse monoclonal (D-1)
  • western blot; human; 1:1000; fig 4
In order to characterize inhibition of neuronal tumor cell proliferation by mitochondrial ferritin, Santa Cruz Biotechnology Gm20746 antibody (Santa Cruz Biotechnology, sc-390558) was used in western blot on human samples at 1:1000 (fig 4). Cell Mol Life Sci (2015) ncbi
Proteintech Group
rabbit polyclonal
  • immunocytochemistry; human; 1:100; fig 5
  • western blot; human; 1:500; fig 6
Proteintech Group Gm20746 antibody (Proteintech, 10727-1-AP) was used in immunocytochemistry on human samples at 1:100 (fig 5) and in western blot on human samples at 1:500 (fig 6). Nat Cell Biol (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100
Proteintech Group Gm20746 antibody (Proteintech, 10727-1-AP) was used in immunohistochemistry - paraffin section on human samples at 1:100. Ann Neurol (2013) ncbi
Articles Reviewed
  1. Wang Z, Ding Y, Wang X, Lu S, Wang C, He C, et al. Pseudolaric acid B triggers ferroptosis in glioma cells via activation of Nox4 and inhibition of xCT. Cancer Lett. 2018;428:21-33 pubmed publisher
  2. Wang Y, Chang S, Wu Q, Gou Y, Jia L, Cui Y, et al. The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis. Front Aging Neurosci. 2016;8:308 pubmed publisher
  3. Horniblow R, Henesy D, Iqbal T, Tselepis C. Modulation of iron transport, metabolism and reactive oxygen status by quercetin-iron complexes in vitro. Mol Nutr Food Res. 2017;61: pubmed publisher
  4. Muraro M, Dharmadhikari G, Grün D, Groen N, Dielen T, Jansen E, et al. A Single-Cell Transcriptome Atlas of the Human Pancreas. Cell Syst. 2016;3:385-394.e3 pubmed publisher
  5. Grün D, Muraro M, Boisset J, Wiebrands K, Lyubimova A, Dharmadhikari G, et al. De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data. Cell Stem Cell. 2016;19:266-277 pubmed publisher
  6. Li W, Garringer H, GOODWIN C, Richine B, Acton A, Vanduyn N, et al. Systemic and cerebral iron homeostasis in ferritin knock-out mice. PLoS ONE. 2015;10:e0117435 pubmed publisher
  7. Dowdle W, Nyfeler B, Nagel J, Elling R, Liu S, Triantafellow E, et al. Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat Cell Biol. 2014;16:1069-79 pubmed publisher
  8. Yang N, Tan S, Ng S, Shi Y, Zhou J, Tan K, et al. Artesunate induces cell death in human cancer cells via enhancing lysosomal function and lysosomal degradation of ferritin. J Biol Chem. 2014;289:33425-41 pubmed publisher
  9. Shi Z, Shi F, Wang Y, Sheftel A, Nie G, Zhao Y, et al. Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation. Cell Mol Life Sci. 2015;72:983-97 pubmed publisher
  10. Raha A, VAISHNAV R, FRIEDLAND R, Bomford A, Raha Chowdhury R. The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer's disease. Acta Neuropathol Commun. 2013;1:55 pubmed publisher
  11. Carberry S, Zweyer M, Swandulla D, Ohlendieck K. Comparative proteomic analysis of the contractile-protein-depleted fraction from normal versus dystrophic skeletal muscle. Anal Biochem. 2014;446:108-15 pubmed publisher
  12. Hametner S, Wimmer I, Haider L, Pfeifenbring S, Bruck W, Lassmann H. Iron and neurodegeneration in the multiple sclerosis brain. Ann Neurol. 2013;74:848-61 pubmed publisher