This is a Validated Antibody Database (VAD) review about mouse Gm10053, based on 39 published articles (read how Labome selects the articles), using Gm10053 antibody in all methods. It is aimed to help Labome visitors find the most suited Gm10053 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Gm10053 synonym: ENSMUSG00000058927

Enzo Life Sciences
mouse monoclonal (6H2.B4)
  • immunocytochemistry; human; fig 3
Enzo Life Sciences Gm10053 antibody (Enzo Life Sciences, 6H2-B4) was used in immunocytochemistry on human samples (fig 3). Autophagy (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; rat; loading ...; fig 3c
Cell Signaling Technology Gm10053 antibody (Cell Signaling Technology, 4272) was used in western blot on rat samples (fig 3c). Oncotarget (2018) ncbi
rabbit monoclonal (D18C7)
  • western blot; human; loading ...; fig 7a
In order to study the synergistic antitumor effect of simultaneously targeting CD47 and autophagy in non-small cell lung cancer, Cell Signaling Technology Gm10053 antibody (Cell Signaling, 11940) was used in western blot on human samples (fig 7a). Cancer Immunol Res (2017) ncbi
rabbit monoclonal (136F3)
  • western blot; mouse; 1:1000; loading ...; fig 4c
In order to elucidate the mechanism by which the I4895T mutation in the type 1 ryanodine receptor/Ca(2+) release channel results in disease, Cell Signaling Technology Gm10053 antibody (Cell Signaling, 4280) was used in western blot on mouse samples at 1:1000 (fig 4c). Nat Commun (2017) ncbi
rabbit monoclonal (136F3)
  • western blot; mouse; 1:1000; loading ...; fig 4e
In order to study the contribution of Id1 to brown adipose tissue thermogenesis and to the regulation of beige adipocytes in white adipose tissue, Cell Signaling Technology Gm10053 antibody (Cell Signaling, 4280) was used in western blot on mouse samples at 1:1000 (fig 4e). Diabetes (2017) ncbi
rabbit monoclonal (136F3)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology Gm10053 antibody (Cell Signaling, 4280) was used in western blot on human samples (fig 5a). Sci Rep (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s2n
In order to elucidate that mTORC1 presents tumor suppressor features in conditions of nutrient restrictions, Cell Signaling Technology Gm10053 antibody (Cell Signaling, 4272) was used in western blot on human samples at 1:1000 (fig s2n). Nat Commun (2017) ncbi
rabbit monoclonal (136F3)
  • western blot; rat; loading ...; fig 3b
In order to ask if SK channels in the mitochondria inner membrane play an important role in regulating mitochondrial function in chronic cardiac diseases, Cell Signaling Technology Gm10053 antibody (Cell Signaling, 136F3) was used in western blot on rat samples (fig 3b). Cardiovasc Res (2017) ncbi
rabbit monoclonal (D18C7)
  • western blot; rat; 1:1000; loading ...; fig 7a
In order to assess the possible mechanism underlying the protective effect of tetramethylpyrazine against disuse-induced muscle atrophy, Cell Signaling Technology Gm10053 antibody (Cell Signaling, 11940T) was used in western blot on rat samples at 1:1000 (fig 7a). Appl Physiol Nutr Metab (2017) ncbi
rabbit monoclonal (136F3)
  • western blot; mouse; 1:1000; loading ...; fig 2e
In order to report that maternal resveratrol intervention protects offspring against high-fat diet-induced obesity, Cell Signaling Technology Gm10053 antibody (Cell Signaling, 4280) was used in western blot on mouse samples at 1:1000 (fig 2e). J Physiol (2017) ncbi
rabbit monoclonal (D18C7)
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology Gm10053 antibody (Cell Signaling, 11940) was used in western blot on mouse samples (fig 4a). Front Physiol (2016) ncbi
rabbit monoclonal (D18C7)
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology Gm10053 antibody (Cell Signaling, 11940S) was used in western blot on human samples (fig 2c). Sci Rep (2016) ncbi
rabbit monoclonal (136F3)
  • western blot; human; 1:500; loading ...; fig 6c
Cell Signaling Technology Gm10053 antibody (Cell Signaling, 4280) was used in western blot on human samples at 1:500 (fig 6c). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 1b
In order to elucidate how FADD contributes to mitochondrial-associated apoptosis, Cell Signaling Technology Gm10053 antibody (Cell Signaling, 4272S) was used in western blot on human samples at 1:500 (fig 1b). Mol Cell Biochem (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4b
In order to use a mitochondrial single-channel patch clamp and cyclophilin D-deficient mice with streptozotocin-induced diabetes to study mitochondrial dysfunction, Cell Signaling Technology Gm10053 antibody (Cell signaling, 4272s) was used in western blot on mouse samples (fig 4b). Diabetes (2016) ncbi
rabbit monoclonal (136F3)
  • western blot; human; 1:1000; fig 2
In order to create and assess the potential use of Adpa manganese as an antitumor agent, Cell Signaling Technology Gm10053 antibody (Cell Signaling, 4280) was used in western blot on human samples at 1:1000 (fig 2). Mol Med Rep (2016) ncbi
rabbit monoclonal (136F3)
  • western blot; human; loading ...; fig 4d
Cell Signaling Technology Gm10053 antibody (Cell Signaling Technology, 4280) was used in western blot on human samples (fig 4d). FEBS Open Bio (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:500; fig 4f
In order to show how FADD regulates NF-kappaB activation and promotes ubiquitination of cFLIPL, which induces apoptosis, Cell Signaling Technology Gm10053 antibody (Cell Signaling Technology, 4272S) was used in western blot on human samples at 1:500 (fig 4f). Sci Rep (2016) ncbi
rabbit monoclonal (136F3)
  • western blot; mouse; 1:1000; fig 4
Cell Signaling Technology Gm10053 antibody (Cell Signaling, 4280) was used in western blot on mouse samples at 1:1000 (fig 4). Sci Rep (2016) ncbi
rabbit monoclonal (D18C7)
  • western blot; human; 1:1000; fig 4
In order to study increased dissociation of hexokinase II from mitochondrial outer membrane by overexpression or ErbB2 rendering breast cancer cells susceptible to 3-BrPA, Cell Signaling Technology Gm10053 antibody (Cell signaling, 11940) was used in western blot on human samples at 1:1000 (fig 4). Oncol Lett (2016) ncbi
rabbit monoclonal (D18C7)
  • western blot; human; 1:2000; fig 4
Cell Signaling Technology Gm10053 antibody (Cell Signaling Technology, 11940) was used in western blot on human samples at 1:2000 (fig 4). Int J Mol Med (2016) ncbi
rabbit monoclonal (136F3)
  • western blot; mouse; 1:100; tbl 1
In order to elucidate a deletion of AMP-activated protein kinase in mouse Sertoli cells that modify germ cell quality, Cell Signaling Technology Gm10053 antibody (Cell Signalling, 4280) was used in western blot on mouse samples at 1:100 (tbl 1). Mol Cell Endocrinol (2016) ncbi
rabbit monoclonal (D18C7)
  • western blot; human; 1:1000; fig 5
Cell Signaling Technology Gm10053 antibody (Cell Signaling, 11940) was used in western blot on human samples at 1:1000 (fig 5). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; rat; fig 3
In order to analyze acute pulmonary exposure to mountaintop removal mining particulate matter and cardiac and mitochondrial dysfunction, Cell Signaling Technology Gm10053 antibody (Cell Signaling Technology, 4272) was used in western blot on rat samples (fig 3). Am J Physiol Heart Circ Physiol (2015) ncbi
rabbit monoclonal (136F3)
  • western blot; mouse; 1:1000; fig s2
Cell Signaling Technology Gm10053 antibody (Cell Signaling Technology, 4280) was used in western blot on mouse samples at 1:1000 (fig s2). Nat Immunol (2015) ncbi
rabbit polyclonal
  • proximity ligation assay; mouse; fig 4
  • immunohistochemistry - frozen section; mouse; fig 4
Cell Signaling Technology Gm10053 antibody (Cell signaling, 4272) was used in proximity ligation assay on mouse samples (fig 4) and in immunohistochemistry - frozen section on mouse samples (fig 4). PLoS ONE (2015) ncbi
rabbit monoclonal (D18C7)
  • western blot; rat; 1:1000
In order to expand our understanding of the mechanisms involved in Pb-induced mitochondrial apoptosis, Cell Signaling Technology Gm10053 antibody (Cell signaling technology, 11940) was used in western blot on rat samples at 1:1000. Arch Toxicol (2016) ncbi
rabbit polyclonal
  • western blot; rat; fig 4
Cell Signaling Technology Gm10053 antibody (Cell signaling, 4272s) was used in western blot on rat samples (fig 4). Int J Mol Med (2015) ncbi
rabbit monoclonal (D18C7)
  • western blot; mouse
Cell Signaling Technology Gm10053 antibody (Cell Signaling Technology, D18C7) was used in western blot on mouse samples . Oncogene (2016) ncbi
rabbit monoclonal (D18C7)
  • western blot; rat; fig 4
In order to test if acute pharmacological activation of AKT induces cardioprotection, Cell Signaling Technology Gm10053 antibody (Cell Signaling, 11940) was used in western blot on rat samples (fig 4). J Transl Med (2015) ncbi
rabbit monoclonal (136F3)
  • western blot; human; loading ...; fig 4D
Cell Signaling Technology Gm10053 antibody (Cell Signaling, 4280) was used in western blot on human samples (fig 4D). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 6
Cell Signaling Technology Gm10053 antibody (Cell Signaling, 4272S) was used in western blot on mouse samples (fig 6). Circ Res (2015) ncbi
rabbit monoclonal (136F3)
  • western blot; mouse
Cell Signaling Technology Gm10053 antibody (Cell Signaling Technology, 4280) was used in western blot on mouse samples . Br J Nutr (2014) ncbi
rabbit polyclonal
  • western blot; rat
Cell Signaling Technology Gm10053 antibody (CST, 4272) was used in western blot on rat samples . FASEB J (2014) ncbi
rabbit polyclonal
  • western blot; rat; fig 10
Cell Signaling Technology Gm10053 antibody (Cell Signaling Technologies, 4272) was used in western blot on rat samples (fig 10). Nat Protoc (2014) ncbi
rabbit monoclonal (D18C7)
  • western blot; mouse
Cell Signaling Technology Gm10053 antibody (Cell Signaling, 11940) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
rabbit monoclonal (D18C7)
  • western blot; mouse; 1:1000
Cell Signaling Technology Gm10053 antibody (Cell Signaling Technology, 11940) was used in western blot on mouse samples at 1:1000. J Biol Chem (2014) ncbi
rabbit monoclonal (136F3)
  • western blot; human; fig s5
Cell Signaling Technology Gm10053 antibody (Cell Signaling, 4280) was used in western blot on human samples (fig s5). Nat Chem Biol (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse
Cell Signaling Technology Gm10053 antibody (Cell Signaling Technology, 4272) was used in immunohistochemistry - frozen section on mouse samples . J Biol Chem (2012) ncbi
Articles Reviewed
  1. Kim J, Shin S, Kang J, Kim J. HX-1171 attenuates pancreatic β-cell apoptosis and hyperglycemia-mediated oxidative stress via Nrf2 activation in streptozotocin-induced diabetic model. Oncotarget. 2018;9:24260-24271 pubmed publisher
  2. Zhang X, Fan J, Wang S, Li Y, Wang Y, Li S, et al. Targeting CD47 and Autophagy Elicited Enhanced Antitumor Effects in Non-Small Cell Lung Cancer. Cancer Immunol Res. 2017;5:363-375 pubmed publisher
  3. Lee C, Hanna A, Wang H, Dagnino Acosta A, Joshi A, Knoblauch M, et al. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017;8:14659 pubmed publisher
  4. Patil M, Sharma B, Elattar S, Chang J, Kapil S, Yuan J, et al. Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning. Diabetes. 2017;66:1611-1625 pubmed publisher
  5. Møller A, Kampmann U, Hedegaard J, Thorsen K, Nordentoft I, Vendelbo M, et al. Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes. Sci Rep. 2017;7:43775 pubmed publisher
  6. Villar V, Nguyen T, Delcroix V, Terés S, Bouchecareilh M, Salin B, et al. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Nat Commun. 2017;8:14124 pubmed publisher
  7. Kim T, Terentyeva R, Roder K, Li W, Liu M, Greener I, et al. SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR. Cardiovasc Res. 2017;113:343-353 pubmed publisher
  8. Hu N, Chang H, Du B, Zhang Q, Arfat Y, Dang K, et al. Tetramethylpyrazine ameliorated disuse-induced gastrocnemius muscle atrophy in hindlimb unloading rats through suppression of Ca2+/ROS-mediated apoptosis. Appl Physiol Nutr Metab. 2017;42:117-127 pubmed publisher
  9. Zou T, Chen D, Yang Q, Wang B, Zhu M, Nathanielsz P, et al. Resveratrol supplementation of high-fat diet-fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring. J Physiol. 2017;595:1547-1562 pubmed publisher
  10. Barreto R, Mandili G, Witzmann F, Novelli F, Zimmers T, Bonetto A. Cancer and Chemotherapy Contribute to Muscle Loss by Activating Common Signaling Pathways. Front Physiol. 2016;7:472 pubmed
  11. Wang C, Zhang F, Cao Y, Zhang M, Wang A, Xu M, et al. Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress. Sci Rep. 2016;6:34330 pubmed publisher
  12. Cao R, Meng Z, Liu T, Wang G, Qian G, Cao T, et al. Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway. Oncotarget. 2016;7:72941-72960 pubmed publisher
  13. Ranjan K, Pathak C. Expression of FADD and cFLIPL balances mitochondrial integrity and redox signaling to substantiate apoptotic cell death. Mol Cell Biochem. 2016;422:135-150 pubmed
  14. Yan S, Du F, Wu L, Zhang Z, Zhong C, Yu Q, et al. F1F0 ATP Synthase-Cyclophilin D Interaction Contributes to Diabetes-Induced Synaptic Dysfunction and Cognitive Decline. Diabetes. 2016;65:3482-3494 pubmed
  15. Geng J, Li J, Huang T, Zhao K, Chen Q, Guo W, et al. A novel manganese complex selectively induces malignant glioma cell death by targeting mitochondria. Mol Med Rep. 2016;14:1970-8 pubmed publisher
  16. Qi J, Li T, Bian H, Li F, Ju Y, Gao S, et al. SNAI1 promotes the development of HCC through the enhancement of proliferation and inhibition of apoptosis. FEBS Open Bio. 2016;6:326-37 pubmed publisher
  17. Strappazzon F, Di Rita A, Cianfanelli V, D Orazio M, Nazio F, Fimia G, et al. Prosurvival AMBRA1 turns into a proapoptotic BH3-like protein during mitochondrial apoptosis. Autophagy. 2016;12:963-75 pubmed publisher
  18. Ranjan K, Pathak C. FADD regulates NF-κB activation and promotes ubiquitination of cFLIPL to induce apoptosis. Sci Rep. 2016;6:22787 pubmed publisher
  19. Zhao Y, Xu L, Qiao Z, Gao L, Ding S, Ying X, et al. YiXin-Shu, a ShengMai-San-based traditional Chinese medicine formula, attenuates myocardial ischemia/reperfusion injury by suppressing mitochondrial mediated apoptosis and upregulating liver-X-receptor α. Sci Rep. 2016;6:23025 pubmed publisher
  20. Gao S, Chen X, Jin H, Ren S, Liu Z, Fang X, et al. Overexpression of ErbB2 renders breast cancer cells susceptible to 3-BrPA through the increased dissociation of hexokinase II from mitochondrial outer membrane. Oncol Lett. 2016;11:1567-1573 pubmed
  21. Zhang Y, Zou C, Yang S, Fu J. P120 catenin attenuates the angiotensin II-induced apoptosis of human umbilical vein endothelial cells by suppressing the mitochondrial pathway. Int J Mol Med. 2016;37:623-30 pubmed publisher
  22. Bertoldo M, Guibert E, Faure M, Guillou F, Ramé C, Nadal Desbarats L, et al. Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality. Mol Cell Endocrinol. 2016;423:96-112 pubmed publisher
  23. Xu Y, Wu D, Zheng W, Yu F, Yang F, Yao Y, et al. Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. Oncotarget. 2016;7:6146-58 pubmed publisher
  24. Nichols C, Shepherd D, Knuckles T, Thapa D, Stricker J, Stapleton P, et al. Cardiac and mitochondrial dysfunction following acute pulmonary exposure to mountaintop removal mining particulate matter. Am J Physiol Heart Circ Physiol. 2015;309:H2017-30 pubmed publisher
  25. Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H, et al. Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity. Nat Immunol. 2015;16:1142-52 pubmed publisher
  26. Zulliger R, Conley S, Mwoyosvi M, Stuck M, Azadi S, Naash M. SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting. PLoS ONE. 2015;10:e0138508 pubmed publisher
  27. Liu G, Wang Z, Wang Z, Yang D, Liu Z, Wang L. Mitochondrial permeability transition and its regulatory components are implicated in apoptosis of primary cultures of rat proximal tubular cells exposed to lead. Arch Toxicol. 2016;90:1193-209 pubmed publisher
  28. Zhang F, Cui J, Lv B, Yu B. Nicorandil protects mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis. Int J Mol Med. 2015;36:415-23 pubmed publisher
  29. Chen C, Kim K, Lau L. The matricellular protein CCN1 suppresses hepatocarcinogenesis by inhibiting compensatory proliferation. Oncogene. 2016;35:1314-23 pubmed publisher
  30. Moreira J, Wohlwend M, Alves M, Wisløff U, Bye A. A small molecule activator of AKT does not reduce ischemic injury of the rat heart. J Transl Med. 2015;13:76 pubmed publisher
  31. Ma H, Yue X, Gao L, Liang X, Yan W, Zhang Z, et al. ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA. Oncotarget. 2015;6:1049-63 pubmed
  32. Ikeda Y, Shirakabe A, Maejima Y, Zhai P, Sciarretta S, Toli J, et al. Endogenous Drp1 mediates mitochondrial autophagy and protects the heart against energy stress. Circ Res. 2015;116:264-78 pubmed publisher
  33. Sun R, Wang X, Liu Y, Xia M. Dietary supplementation with fish oil alters the expression levels of proteins governing mitochondrial dynamics and prevents high-fat diet-induced endothelial dysfunction. Br J Nutr. 2014;112:145-53 pubmed publisher
  34. Smith I, Godinez G, Singh B, McCaughey K, Alcantara R, Gururaja T, et al. Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction. FASEB J. 2014;28:2790-803 pubmed publisher
  35. Salabei J, Gibb A, Hill B. Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis. Nat Protoc. 2014;9:421-38 pubmed publisher
  36. Mahajan I, Chen M, Muro I, Robertson J, Wright C, Bratton S. BH3-only protein BIM mediates heat shock-induced apoptosis. PLoS ONE. 2014;9:e84388 pubmed publisher
  37. Tsuneki M, Madri J. CD44 regulation of endothelial cell proliferation and apoptosis via modulation of CD31 and VE-cadherin expression. J Biol Chem. 2014;289:5357-70 pubmed publisher
  38. Wang W, Wang Y, Chen H, Xing Y, Li F, Zhang Q, et al. Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway. Nat Chem Biol. 2014;10:133-40 pubmed publisher
  39. Singh K, Shukla P, Quan A, Desjardins J, Lovren F, Pan Y, et al. BRCA2 protein deficiency exaggerates doxorubicin-induced cardiomyocyte apoptosis and cardiac failure. J Biol Chem. 2012;287:6604-14 pubmed publisher