This is a Validated Antibody Database (VAD) review about mouse Gjc2, based on 6 published articles (read how Labome selects the articles), using Gjc2 antibody in all methods. It is aimed to help Labome visitors find the most suited Gjc2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Gjc2 synonym: B230382L12Rik; Cx47; Gja12; gap junction gamma-2 protein; connexin 47 type A; connexin 47 type C; connexin 47 type D; connexin-47; gap junction alpha-12 protein; gap junction membrane channel protein alpha 12; gap junction protein, chi 2

Invitrogen
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; fig 1
In order to compare valve phenotypes of Cx37, Cx43, and Cx47 knockout mice by NFATc1 and connexin expression in normal developing venous valves, segregated Foxc2, and connexin-specific differences, Invitrogen Gjc2 antibody (Invitrogen, 364700) was used in immunohistochemistry - frozen section on mouse samples (fig 1). Dev Biol (2016) ncbi
mouse monoclonal (4A11A2)
  • immunohistochemistry; mouse; 1:500; fig 2
In order to study how different stages of inflammatory demyelination affect oligodendrocyte gap junctions, Invitrogen Gjc2 antibody (Zymed, 37-4500) was used in immunohistochemistry on mouse samples at 1:500 (fig 2). Glia (2012) ncbi
mouse monoclonal (4A11A2)
  • immunohistochemistry - frozen section; mouse; 2 ug/ml
In order to study localization of connexins in the brain, Invitrogen Gjc2 antibody (Invitrogen, 37-4500) was used in immunohistochemistry - frozen section on mouse samples at 2 ug/ml. Eur J Neurosci (2011) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 2 ug/ml
In order to study localization of connexins in the brain, Invitrogen Gjc2 antibody (Invitrogen, 36-4700) was used in immunohistochemistry - frozen section on mouse samples at 2 ug/ml. Eur J Neurosci (2011) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:250; fig 2
In order to characterize Cx47M282T mice, Invitrogen Gjc2 antibody (Invitrogen, 36-4700) was used in immunohistochemistry - frozen section on mouse samples at 1:250 (fig 2). PLoS Genet (2011) ncbi
rabbit polyclonal
  • other; rat; 10 ug/ml; fig 8
In order to determine the abundance and connexin composition of neuronal and glial gap junctions in developing and adult rat and mouse locus coeruleus, Invitrogen Gjc2 antibody (Invitrogen/Zymed, 36-4700) was used in other on rat samples at 10 ug/ml (fig 8). Neuroscience (2007) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:400
  • western blot; mouse
In order to examine the connexin associations at oligodendrocyte/astrocyte gap junctions on oligodendrocytes in normal and Cx32 knockout mice, Invitrogen Gjc2 antibody (Zymed, 36?C4700) was used in immunohistochemistry - frozen section on mouse samples at 1:400 and in western blot on mouse samples . Glia (2003) ncbi
Articles Reviewed
  1. Munger S, Geng X, Srinivasan R, Witte M, Paul D, Simon A. Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice. Dev Biol. 2016;412:173-90 pubmed publisher
  2. Markoullis K, Sargiannidou I, Gardner C, Hadjisavvas A, Reynolds R, Kleopa K. Disruption of oligodendrocyte gap junctions in experimental autoimmune encephalomyelitis. Glia. 2012;60:1053-66 pubmed publisher
  3. Lynn B, Tress O, May D, Willecke K, Nagy J. Ablation of connexin30 in transgenic mice alters expression patterns of connexin26 and connexin32 in glial cells and leptomeninges. Eur J Neurosci. 2011;34:1783-93 pubmed publisher
  4. Tress O, Maglione M, Zlomuzica A, May D, Dicke N, Degen J, et al. Pathologic and phenotypic alterations in a mouse expressing a connexin47 missense mutation that causes Pelizaeus-Merzbacher-like disease in humans. PLoS Genet. 2011;7:e1002146 pubmed publisher
  5. Rash J, Olson C, Davidson K, Yasumura T, Kamasawa N, Nagy J. Identification of connexin36 in gap junctions between neurons in rodent locus coeruleus. Neuroscience. 2007;147:938-56 pubmed
  6. Nagy J, Ionescu A, Lynn B, Rash J. Coupling of astrocyte connexins Cx26, Cx30, Cx43 to oligodendrocyte Cx29, Cx32, Cx47: Implications from normal and connexin32 knockout mice. Glia. 2003;44:205-18 pubmed