This is a Validated Antibody Database (VAD) review about mouse Gclc, based on 27 published articles (read how Labome selects the articles), using Gclc antibody in all methods. It is aimed to help Labome visitors find the most suited Gclc antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Gclc synonym: D9Wsu168e; GLCL-H; Ggcs-hs; Glclc

Abcam
domestic rabbit monoclonal (EP13475)
  • western blot; mouse; 1:1000; loading ...; fig 3b
Abcam Gclc antibody (Abcam, ab190685) was used in western blot on mouse samples at 1:1000 (fig 3b). Int J Mol Sci (2022) ncbi
domestic rabbit monoclonal (EP13475)
  • western blot; human; loading ...; fig 3b
Abcam Gclc antibody (Abcam, ab190685) was used in western blot on human samples (fig 3b). Sci Adv (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 7a
Abcam Gclc antibody (Abcam, ab53179) was used in western blot on mouse samples at 1:500 (fig 7a). Cell Mol Gastroenterol Hepatol (2021) ncbi
domestic rabbit monoclonal (EP13475)
  • western blot; mouse; 1:1000; loading ...; fig s4a
Abcam Gclc antibody (Abcam, Ab190685) was used in western blot on mouse samples at 1:1000 (fig s4a). Cancer Cell (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s5d
Abcam Gclc antibody (Abcam, ab53179) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig s5d). Atherosclerosis (2019) ncbi
domestic rabbit monoclonal (EP13475)
  • western blot; human; 1:10,000; loading ...; fig s1c
Abcam Gclc antibody (Abcam, ab190685) was used in western blot on human samples at 1:10,000 (fig s1c). Atherosclerosis (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3c
Abcam Gclc antibody (Abcam, ab53179) was used in western blot on mouse samples (fig 3c). Neuroscience (2018) ncbi
domestic rabbit monoclonal (EP13475)
  • immunohistochemistry; human; 1:200; fig 1a
Abcam Gclc antibody (Abcam, ab190685) was used in immunohistochemistry on human samples at 1:200 (fig 1a). Am J Physiol Gastrointest Liver Physiol (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 6
Abcam Gclc antibody (Abcam, ab41463) was used in western blot on mouse samples (fig 6). Redox Biol (2016) ncbi
domestic rabbit monoclonal (EP13475)
  • western blot; mouse; 1:25,000; loading ...; fig 2d
Abcam Gclc antibody (Abcam, ab19068) was used in western blot on mouse samples at 1:25,000 (fig 2d). Toxicol Appl Pharmacol (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:500; fig 3
Abcam Gclc antibody (Abcam, ab41463) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 3). J Transl Med (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig 6a
Abcam Gclc antibody (Abcam, ab53179) was used in western blot on mouse samples at 1:2000 (fig 6a). Redox Biol (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (G-12)
  • western blot; mouse; 1:1000; fig s7c
Santa Cruz Biotechnology Gclc antibody (Santa Cruz, sc-166345) was used in western blot on mouse samples at 1:1000 (fig s7c). Nat Commun (2021) ncbi
mouse monoclonal (H-5)
  • western blot; human; loading ...; fig s3f
Santa Cruz Biotechnology Gclc antibody (Santa Cruz, sc390811) was used in western blot on human samples (fig s3f). Nat Commun (2020) ncbi
mouse monoclonal (G-12)
  • western blot; human; 1:200; fig 4
Santa Cruz Biotechnology Gclc antibody (Santa Cruz, sc166345) was used in western blot on human samples at 1:200 (fig 4). Biochem Pharmacol (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; 1:1000
In order to study the epigenetic regulation of oxidative genes involved in the pathogenesis of chronic obstructive pulmonary disease, Invitrogen Gclc antibody (Lab Vision, PA5-19702) was used in western blot on human samples at 1:1000. Chest (2016) ncbi
domestic rabbit polyclonal
In order to test if erythroid 2-like 2 regulates expression of ITPR3, Invitrogen Gclc antibody (Thermo Scientific, PA5-19702) was used . Gastroenterology (2015) ncbi
Bio-Rad
rat monoclonal (LO-ME-3)
  • ELISA; mouse; loading ...; fig 1c
Bio-Rad Gclc antibody (AbD Serotec, LO-ME-3) was used in ELISA on mouse samples (fig 1c). J Exp Med (2017) ncbi
rat monoclonal (LO-ME-3)
Bio-Rad Gclc antibody (AbD, MCA419) was used . Biol Pharm Bull (2015) ncbi
Aviva Systems Biology
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 3d
Aviva Systems Biology Gclc antibody (Aviva biologicals, ARP54577_P050) was used in western blot on human samples at 1:500 (fig 3d). Biomolecules (2019) ncbi
Kamiya Biomedical Company
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig s4d
In order to determine the impact of smooth muscle cell beta-catenin to vascular homeostasis and arterial injury, Kamiya Biomedical Company Gclc antibody (Kamiya biomedical company, MC-352) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig s4d). Arterioscler Thromb Vasc Biol (2017) ncbi
  • immunohistochemistry; mouse; loading ...; fig s4
In order to research the atheroprotective effect of OCT4 in smooth muscle cells, Kamiya Biomedical Company Gclc antibody (Kamia Biomedical Company, MC-352) was used in immunohistochemistry on mouse samples (fig s4). Nat Med (2016) ncbi
  • immunohistochemistry - paraffin section; mouse; fig s1
Kamiya Biomedical Company Gclc antibody (Kamiya Biomedical Company, MC-352) was used in immunohistochemistry - paraffin section on mouse samples (fig s1). Nat Med (2015) ncbi
Vector Laboratories
  • immunohistochemistry; mouse; 1:30; loading ...; fig 5a
Vector Laboratories Gclc antibody (Vector, VP- M664) was used in immunohistochemistry on mouse samples at 1:30 (fig 5a). Sci Rep (2019) ncbi
  • immunohistochemistry - frozen section; mouse; fig 5b
Vector Laboratories Gclc antibody (Vector Laboratories, VP-M664) was used in immunohistochemistry - frozen section on mouse samples (fig 5b). PLoS ONE (2016) ncbi
ECM Biosciences
domestic rabbit polyclonal
  • western blot; mouse; 1 ug/ml; fig 3
In order to determine the role of TRPM7 channel function defects and how they deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture, ECM Biosciences Gclc antibody (ECM Biosciences, MP3791) was used in western blot on mouse samples at 1 ug/ml (fig 3). Nat Commun (2016) ncbi
ATCC
mouse monoclonal
  • immunohistochemistry; mouse; fig s1
ATCC Gclc antibody (ATCC, HB287) was used in immunohistochemistry on mouse samples (fig s1). Sci Rep (2016) ncbi
mouse monoclonal
  • immunohistochemistry; mouse; fig s1
ATCC Gclc antibody (ATCC, HB283) was used in immunohistochemistry on mouse samples (fig s1). Sci Rep (2016) ncbi
Developmental Studies Hybridoma Bank
mouse monoclonal (2E9)
  • immunohistochemistry - paraffin section; mouse; 1:100
In order to study the role of endothelial cells in myofiber differentiation and the development of bioengineered muscle tissue in vivo, Developmental Studies Hybridoma Bank Gclc antibody (DSHB, 2E9) was used in immunohistochemistry - paraffin section on mouse samples at 1:100. Biomaterials (2013) ncbi
Articles Reviewed
  1. Stancic A, Velickovic K, Markelic M, Grigorov I, Saksida T, Savić N, et al. Involvement of Ferroptosis in Diabetes-Induced Liver Pathology. Int J Mol Sci. 2022;23: pubmed publisher
  2. von M xe4 ssenhausen A, Zamora Gonzalez N, Maremonti F, Belavgeni A, Tonnus W, Meyer C, et al. Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion. Sci Adv. 2022;8:eabl8920 pubmed publisher
  3. Bebber C, Thomas E, Stroh J, Chen Z, Androulidaki A, Schmitt A, et al. Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes. Nat Commun. 2021;12:2048 pubmed publisher
  4. Buitrago Molina L, Marhenke S, Becker D, Geffers R, Itzel T, Teufel A, et al. p53-Independent Induction of p21 Fails to Control Regeneration and Hepatocarcinogenesis in a Murine Liver Injury Model. Cell Mol Gastroenterol Hepatol. 2021;11:1387-1404 pubmed publisher
  5. Cao J, Chen X, Jiang L, Lu B, Yuan M, Zhu D, et al. DJ-1 suppresses ferroptosis through preserving the activity of S-adenosyl homocysteine hydrolase. Nat Commun. 2020;11:1251 pubmed publisher
  6. Cheung E, DeNicola G, Nixon C, Blyth K, Labuschagne C, Tuveson D, et al. Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer. Cancer Cell. 2020;37:168-182.e4 pubmed publisher
  7. Ribeiro A, Souza L, Almeida C, Ishiba R, Fernandes S, Guerrieri D, et al. Muscle satellite cells and impaired late stage regeneration in different murine models for muscular dystrophies. Sci Rep. 2019;9:11842 pubmed publisher
  8. Zhu Y, Zhang Y, Huang X, Xie Y, Qu Y, Long H, et al. Z-Ligustilide protects vascular endothelial cells from oxidative stress and rescues high fat diet-induced atherosclerosis by activating multiple NRF2 downstream genes. Atherosclerosis. 2019;284:110-120 pubmed publisher
  9. McCambridge G, Agrawal M, Keady A, Kern P, Hasturk H, Nikolajczyk B, et al. Saturated Fatty Acid Activates T Cell Inflammation Through a Nicotinamide Nucleotide Transhydrogenase (NNT)-Dependent Mechanism. Biomolecules. 2019;9: pubmed publisher
  10. Lv W, Deng B, Duan W, Li Y, Liu Y, Li Z, et al. Schwann Cell Plasticity is Regulated by a Weakened Intrinsic Antioxidant Defense System in Acute Peripheral Nerve Injury. Neuroscience. 2018;382:1-13 pubmed publisher
  11. Brown I, Gulbransen B. The antioxidant glutathione protects against enteric neuron death in situ, but its depletion is protective during colitis. Am J Physiol Gastrointest Liver Physiol. 2018;314:G39-G52 pubmed publisher
  12. Laffont S, Blanquart E, Savignac M, Cenac C, Laverny G, Metzger D, et al. Androgen signaling negatively controls group 2 innate lymphoid cells. J Exp Med. 2017;214:1581-1592 pubmed publisher
  13. Riascos Bernal D, Chinnasamy P, Gross J, Almonte V, Egaña Gorroño L, Parikh D, et al. Inhibition of Smooth Muscle ?-Catenin Hinders Neointima Formation After Vascular Injury. Arterioscler Thromb Vasc Biol. 2017;37:879-888 pubmed publisher
  14. Shanmugam G, Narasimhan M, Sakthivel R, Kumar R R, Davidson C, Palaniappan S, et al. A biphasic effect of TNF-? in regulation of the Keap1/Nrf2 pathway in cardiomyocytes. Redox Biol. 2016;9:77-89 pubmed publisher
  15. Wang Y, Chen M, Zhang Y, Huo T, Fang Y, Jiao X, et al. Effects of realgar on GSH synthesis in the mouse hippocampus: Involvement of system XAG(-), system XC(-), MRP-1 and Nrf2. Toxicol Appl Pharmacol. 2016;308:91-101 pubmed publisher
  16. Morisaki Y, Niikura M, Watanabe M, Onishi K, Tanabe S, Moriwaki Y, et al. Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9. Sci Rep. 2016;6:27354 pubmed publisher
  17. Cherepanova O, Gomez D, Shankman L, Swiatlowska P, Williams J, Sarmento O, et al. Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective. Nat Med. 2016;22:657-65 pubmed publisher
  18. Kumar R, Narasimhan M, Shanmugam G, Hong J, Devarajan A, Palaniappan S, et al. Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress. J Transl Med. 2016;14:86 pubmed publisher
  19. Stritt S, Nurden P, Favier R, Favier M, Ferioli S, Gotru S, et al. Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture. Nat Commun. 2016;7:11097 pubmed publisher
  20. Calyjur P, Almeida C, Ayub Guerrieri D, Ribeiro A, Fernandes S, Ishiba R, et al. The mdx Mutation in the 129/Sv Background Results in a Milder Phenotype: Transcriptome Comparative Analysis Searching for the Protective Factors. PLoS ONE. 2016;11:e0150748 pubmed publisher
  21. Koyani C, Kitz K, Rossmann C, Bernhart E, Huber E, Trummer C, et al. Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death. Biochem Pharmacol. 2016;104:29-41 pubmed publisher
  22. Chaiprasongsuk A, Onkoksoong T, Pluemsamran T, Limsaengurai S, Panich U. Photoprotection by dietary phenolics against melanogenesis induced by UVA through Nrf2-dependent antioxidant responses. Redox Biol. 2016;8:79-90 pubmed publisher
  23. Matsui N, Ito D, Takabatake Y, Nashioka E, Tada S, Kanagawa M, et al. Compound 48/80, a Mast Cell Stimulator, Enhances Synthesis of IgE and IgG Induced by Intranasal Application of Ovalbumin in Mice. Biol Pharm Bull. 2015;38:1954-9 pubmed publisher
  24. Cheng L, Liu J, Li B, Liu S, Li X, Tu H. Cigarette Smoke-Induced Hypermethylation of the GCLC Gene Is Associated With COPD. Chest. 2016;149:474-482 pubmed publisher
  25. Shankman L, Gomez D, Cherepanova O, Salmon M, Alencar G, Haskins R, et al. KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nat Med. 2015;21:628-37 pubmed publisher
  26. Weerachayaphorn J, Amaya M, Spirli C, Chansela P, Mitchell Richards K, Ananthanarayanan M, et al. Nuclear Factor, Erythroid 2-Like 2 Regulates Expression of Type 3 Inositol 1,4,5-Trisphosphate Receptor and Calcium Signaling in Cholangiocytes. Gastroenterology. 2015;149:211-222.e10 pubmed publisher
  27. Criswell T, Corona B, Wang Z, Zhou Y, Niu G, Xu Y, et al. The role of endothelial cells in myofiber differentiation and the vascularization and innervation of bioengineered muscle tissue in vivo. Biomaterials. 2013;34:140-9 pubmed publisher